Our Funded Research Projects

Updated April 2024

Title Principal Investigator / Supervisor Program Project Start Date Project End Date Sort ascending Total $ Awarded
Novel techniques in transfusion medicine: Advancing clinical investigations and discovering new ligands of platelets Principal Investigator: BECKETT, Andrew

Co-Investigator(s) / Trainee: SHOARA, Aron
Postdoctoral Fellowship Program 164200.0
Clot-targeting the novel thrombolytic activity of recombinant factor X Principal Investigator: PRYZDIAL, Ed

Co-Investigator(s) / Trainee: HAO, Lihua
Postdoctoral Fellowship Program 164200.0
Developing educational tools and resources to improve living donor care Principal Investigator: SANDAL, Shaifali

Co-Investigator(s) / Trainee: NUGUS, Peter, FORTIN, Marie-Chantal, LOBAN, Katya, BUGEJA, Ann, MAINRA, Rahul, DIPCHAND, Christine, BADENOCH, Heather
BloodTechNet Award Program 50000.0
Monovalent anti-FcγRI strategy in transfusion medicine Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: TUNDIDOR, Yaima
Postdoctoral Fellowship Program 162400.0
Innovative strategies for detection of uncharacterized platelet ligands from blood plasma and autoantibodies in blood Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee: SLAVKOVIC, Sladjana
Postdoctoral Fellowship Program 162400.0
Fc receptor blockade in transfusion medicine Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: NI, Heyu, GUPTA, Akash, SHEHATA, Nadine, KJELDSEN-KRAGH, Jens, NEWMAN, Peter J., CSERTI-GAZDEWICH, Christine, RAVETCH, Jeffery
Intramural Research Grant Program 400000.0
Revisiting the universal donor: Does exposure to O blood products affect patient outcomes? Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee: ACKER, Jason, BUCKSTEIN, Rena, CALLUM, Jeannie, COOK, Richard, HEDDLE, Nancy, SOLH, Ziad, WEBERT, Kathryn, BARTY, Rebecca, LEBER, Brian, LALIT, Saini
Intramural Research Grant Program 378365.0
Controlling coagulopathy and bleeding in a mouse model of hemorrhagic shock Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: NAZY, Ishac
Intramural Research Grant Program 274854.0
Replacing plasma-derived C1 Esterase inhibitor Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: SIVANANTHAN, Sangavi
Graduate Fellowship Program 70000.0
Donor factors and product quality Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: YAZDANBAKHSH, Mahsa
Graduate Fellowship Program 122000.0
Preservation of red blood cells by the novel isochoric oil-sealing supercooling system Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: ZHAO, Yuanheng
Postdoctoral Fellowship Program 167000.0
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: LIN, Yulia

Co-Investigator(s) / Trainee: ROTIN, Lianne
Elianna Saidenberg Transfusion Medicine Traineeship Award 210000.0
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: LIN, Yulia

Co-Investigator(s) / Trainee: RAZA, Sheharyar
Elianna Saidenberg Transfusion Medicine Traineeship Award 210000.0
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: LIN, Yulia

Co-Investigator(s) / Trainee: ARYA, Sumedha
Elianna Saidenberg Transfusion Medicine Traineeship Award 210000.0
Transcriptome analyses of Staphylococcus aureus grown in platelet concentrates with focus on virulence Principal Investigator: RAMIREZ-ARCOS, Sandra

Co-Investigator(s) / Trainee: DA SILVA PAREDES, Carina
Graduate Fellowship Program 122000.0
CD71 Erythroid Cells, RBC Clearance and Sepsis in Donor - Recipient Sex- Mismatched Transfusion Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: LI, Wenhui
Graduate Fellowship Program 70000.0
Anemia-induced bleeding in thrombocytopenic patients with blood cancer Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee: MODI, Dimpy
Graduate Fellowship Program 70000.0
Fc receptor blockade related to fetal and neonatal alloimmune thrombocytopenia Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: TAWHIDI, Zoya
Graduate Fellowship Program 70000.0
Improving blood product quality Principal Investigator: DEVINE, Dana

Co-Investigator(s) / Trainee: MA, Hongshen, JOHNSON, James, D'ALESSANDRO, Angelo
Intramural Research Grant Program 304462.0
Cold- versus room-temperature storage of platelets for bleeding in hematologic malignancy trials (CoVeRTS-HM Trial) Principal Investigator: MACK, Johnathan

Co-Investigator(s) / Trainee: TINMOUTH, Alan, FERGUSSON, Dean, SABLOFF, Mitchell
Blood Efficiency Accelerator Program 26385.0
Demonstration of genetic blood group transition in patients undergoing ABO-mismatched allogeneic hematopoietic stem cell transplantation by peripheral blood quantitative polymerase chain reaction targeting the ABO locus – Full Study Principal Investigator: MCGINNIS, ERIC

Co-Investigator(s) / Trainee: SHIH, Andrew, WANG, Xiu Qing, STUBBINS, Ryan, HUDOBA, Monika, PETRASZKO, Tanya
Blood Efficiency Accelerator Program 30000.0
Hypothermic Storage as an Alternative to Irradiation of Red Cell Concentrates Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: CLARKE, Gwen, NAHIRNIAK, Susan, BRANDON-COATHAM, Mackenzie, OLAFSON, Carly
Blood Efficiency Accelerator Program 30000.0
Red Cell Transfusion Rate and Allosensitization in Patients with End Stage Kidney Disease Principal Investigator: ZIMMERMAN, Deborah

Co-Investigator(s) / Trainee: FERGUSSON, Dean, FORSTER, Alan, KNOLL, Greg, CALLUM, Jeannie, TINMOUTH, Alan, MACK, Johnathan, CLARK, Edward, RAMSAY, Tim, PERELMAN, Iris
Blood Efficiency Accelerator Program 29015.7
A Simulation Model to Inform Best Practices for Inventory Management of Group O Negative Red Blood Cells Principal Investigator: RUTHERFORD, Alexander

Co-Investigator(s) / Trainee: BLAKE, John, SHIH, Andrew, MORRISON, Douglas, SAREMI, Alireza
Blood Efficiency Accelerator Program 29500.0
RBC hemolysis and cellular effector mechanisms (RHANCEM) Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: CSERTI-GAZDEWICH, Christine, PENDERGRAST,Jacob, CALLUM, Jeannie, YI, Qilong
Intramural Research Grant Program 399927.3
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: ZELLER, Michelle

Co-Investigator(s) / Trainee: GABARIN, Nadia
Elianna Saidenberg Transfusion Medicine Traineeship Award 210000.0
Determining potential policy solutions for normothermic regional perfusion in organ donation in Canada through analysis and resolution of two key ethical challenges Principal Investigator: WEIJER, Charles

Co-Investigator(s) / Trainee: BADENOCH, Heather, BASMAJI, John, BRAHMANIA, Mayur, CHANDLER, Jennifer, HEALEY, Andrew, LINGARD, Lorelei, MURPHY, Nicholas, OTT, Mary, SHEMIE, Sam, SKARO, Anton, SLESSAREV, Marat
James Kreppner Award Program 50000.0
Identifying biomarkers for Staphylococcus aureus contamination of platelet component Principal Investigator: RAMIREZ-ARCOS, Sandra

Co-Investigator(s) / Trainee: CHI, Sylvia Ighem
Postdoctoral Fellowship Program 150000.0
Rationale, development, and feasibility of a prehospital transfusion registry Principal Investigator: NOLAN, Brodie

Co-Investigator(s) / Trainee: PEDDLE, Michael, LIN, Yulia, KHANDELWAL, Aditi, MCGOWAN, Melissa, TROJANOWSKI, Jan, SHIH, Andrew
Blood Efficiency Accelerator Program 30000.0
Development of porcine equivalent RCC and plasma units for translatable ex vivo organ perfusion research Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: FREED, Darren
Intramural Research Grant Program 121834.0
Can pre-operative anemia be timely identified and optimized in patients awaiting primary arthroplasty surgery? A randomized clinical trial Principal Investigator: GRAMMATOPOULOS, George

Co-Investigator(s) / Trainee: FERGUSSON, Dean, RAMSAY, Tim, TINMOUTH, Alan, GAGNE, Sylvain, MACK, Johnathan, BELZILE, Etienne, BEALE, Paul, THAVORN, Kednapa, TOUCHIE, Donna, GERMAIN, Genevieve, LAROCHE, Vincent
Intramural Research Grant Program 276081.0
Small molecule inhibitors of phagocytosis Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: KOTRA, Lakshmi P.
Intramural Research Grant Program 399130.0
A clinical comparison of cold-stored and room temperature-stored allogeneic platelet transfusions in bleeding adult cardiac surgery patients - A randomized multicentre pilot study (PLTS-1 study) Principal Investigator: BARTOSZKO, Justyna

Co-Investigator(s) / Trainee: CALLUM, Jeannie, DEVINE, Dana, KARKOUTI, Keyvan, KAHR, Walter, MCVEY, Mark, PEER, Miki, RAO, Vivek, ABRAHAMYAN, Lusine, LIEBERMAN, Lani, MEWHORT, Holly
Intramural Research Grant Program 242617.0
Enabling next generation hematopoietic-based therapeutics and manufacturing Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: MCCOMB, Scott, JEZIERSKI, Anna, MAGALHAES, Ana, IQBAL, Umer
Intramural Research Grant Program 300000.0
Biomarkers in patients with anemia-induced thrombocytopenic bleeding (BAIT): A pilot study Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee: WEBERT, Kathryn, LIAW, Patricia, BERG, Tobias, HEDDLE, Nancy
Intramural Research Grant Program 200000.0
Options for increasing plasma supply in Canada: A health economic preference and modelling study Principal Investigator: HOLLOWAY, Kelly

Co-Investigator(s) / Trainee: KENNEDY, Kevin
CIHR Health System Impact Fellowship 108500.0
Evaluating transfusion medicine patterns of practice across GEMINI sites Principal Investigator: CALLUM, Jeannie

Co-Investigator(s) / Trainee: ARNOLD, Donald, VERMA, Amol, SRIVASTAVA, Siddhartha, CHENG, Calvino, ESMAIL, Tariq, DESVEAUX, Laura, TYRYSHKIN, Kathrin, KARKOUTI, Keyvan, LADHA, Karim, LI, Na, PAVENSKI, Katerina, PENDERGRAST, Jacob, PRESSEAU, Justin, SCHNEIDER, Henry, SHEHATA, Nadine, SHIH, Andrew, THIRUMURTHY, Harsha, BREHAUT, Jamie, RAZAK, Fahad, MCLCEARY, Nicola, ZUCKERMAN, Jesse
Kenneth J. Fyke Award Program 98822.0
Modified platelet storage containers to improve quality during storage Principal Investigator: KIZHAKKEDATHU, Jayachandran

Co-Investigator(s) / Trainee: PEREYRA DOS SANTOS, Nicolas
Graduate Fellowship Program 52000.0
Leveraging equity-focused implementation science to evaluate and support the re-integration of men who have sex with men into the blood donation system Principal Investigator: GOLDMAN, Mindy

Co-Investigator(s) / Trainee: VESNAVER, Elisabeth
CIHR Health System Impact Fellowship 108500.0
Generation of a coagulation factor-based thrombotic agent Principal Investigator: PRYZDIAL, Ed

Co-Investigator(s) / Trainee: WITT, Alexandra
Graduate Fellowship Program 52000.0
COVID-19 vaccination refusal and access to transplantation: an ethical conundrum. A legal analysis and a qualitative study with key stakeholders Principal Investigator: FORTIN, Marie-Chantal

Co-Investigator(s) / Trainee: CHANDLER, Jennifer, GILL, Justin, GOLDBERG, Aviva, GRUBEN, Vanessa
James Kreppner Award Program 49952.0
Replacement of IVIg by small molecule inhibitors of phagocytosis Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: LORIAMINI, Melika
Graduate Fellowship Program 112333.0
Defining the stem cell regulatory functions of GAS6 and FTO Principal Investigator: MAGANTI, Harinad

Co-Investigator(s) / Trainee: PASALA, Ajay
Graduate Fellowship Program 52000.0
Synthesis and live cell imaging of ice recrystallization inhibitors in red blood cells Principal Investigator: BEN, Robert

Co-Investigator(s) / Trainee: MCMUNN, Leah
Graduate Fellowship Program 112333.0
Assessing acceptability, understanding and effectiveness of alternative screening questions for current donors Principal Investigator: FISHER, William

Co-Investigator(s) / Trainee: GOLDMAN, Mindy, FOSTER, Terrie, O'BRIEN, Sheila, HOFKIRCHNER, Alexander, Principal Investigator: HAW, Jennie

Co-Investigator(s) / Trainee: GOLDMAN, Mindy, FOSTER, Terrie, O'BRIEN, Sheila, HOFKIRCHNER, Alexander
MSM Plasma Program 129400.0
Assessing the relationship between red blood cell deformability and transfusion lifetime Principal Investigator: MA, Hongshen

Co-Investigator(s) / Trainee: LAMOUREUX, Erik
Graduate Fellowship Program 52000.0
Awareness and understanding of apheresis plasma donation and effectiveness of alternative donor screening questions for diverse gbMSM and trans populations Principal Investigator: GAHAGAN, Jacqueline

Co-Investigator(s) / Trainee: HAW, Jennie, LACHOWSKY, Nathan, DRYDEN, OmiSoore, MANNING, Eli, FOSTER, Terrie, O'BRIEN, Sheila, HACHETTE, Todd, MULLOWNEY, Mike
MSM Plasma Program 200500.0
Translating novel clotting factor X function to treat thrombosis Principal Investigator: PRYZDIAL, Ed

Co-Investigator(s) / Trainee: MACVICAR, Brian, SHEFFIELD, William
Intramural Research Grant Program 369052.0
Transfusion CONsent by a Standardized Evidence-based Novel Tool (Transfusion- CONSENT): Creating and validating novel tools to assess competence in obtaining transfusion consent Principal Investigator: LAUREANO, Marissa

Co-Investigator(s) / Trainee: KHANDELWAL, Aditi, HASPEL, Richard, FUNG, Mark, LANE, Shannon, ZELLER, Michelle
BloodTechNet Award Program 8524.0
Assessing the acceptability and feasibility of a plasma donation program for gbMSM in Montréal from the point of view of cis and trans gbMSM, volunteers from Héma-Québec, current donors, and plasma product recipients Principal Investigator: OTIS, Joanne

Co-Investigator(s) / Trainee: GERMAIN, Marc, HAW, Jennie, MONTEITH, Kenneth, MYHAL, Geneviève, PRESSEAU, Justin, PIRNAT, Bojan, LAPIERRE, Don
MSM Plasma Program 390970.0