Our Funded Research Projects
Updated February 2025
| Title | Principal Investigator / Supervisor | Program | Project Start Date | Project End Date Sort ascending | Total $ Awarded |
|---|---|---|---|---|---|
| The threshold or operative hemoglobin trigger for red blood cell transfustion pilot trial (TOPGUN-pilot) | Principal Investigator: MARTEL, Guillaume Co-Investigator(s) / Trainee: MCISAAC, Daniel, FERGUSSON, Dean, TINMOUTH, Alan, BREAU, Rodney, CARRIER, Francois Martin, VERRET, Michael, TALJAARD, Monica, BROUSSEAU, Karine |
Intramural Research Grant Program | $400,000 | ||
| Increased cell product potency through improved storage solution | Principal Investigator: PINEAULT, Nicolas Co-Investigator(s) / Trainee: BEN, Robert |
Intramural Research Grant Program | $261,812 | ||
| Novel techniques in transfusion medicine: Advancing clinical investigations and discovering new ligands of platelets | Principal Investigator: BECKETT, Andrew Co-Investigator(s) / Trainee: SHOARA, Aron |
Postdoctoral Fellowship Program | $164,200 | ||
| Improving platelet storage and blood transfusion: unveiling the role of apolipoprotein A-IV | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: LAZARUS, Alan, BRANCH, Donald |
Intramural Research Grant Program | $400,000 | ||
| Accelerating the clinical translation of “off the shelf” NK cell products for immunotherapies | Principal Investigator: MAGANTI, Harinad Co-Investigator(s) / Trainee: JEZIERSKI, Anna, ALLAN, David |
Intramural Research Grant Program | $300,000 | ||
| Blocking human Fcγ receptor 1 in transfusion medicine | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: NI, Heyu |
Intramural Research Grant Program | $400,000 | ||
| Facilitating RBC-mediated Nitric Oxide Release and Boosting Antioxidant Capacity during Ex Vivo Heart Perfusions as a Strategy to Improve Oxygen Delivery | Principal Investigator: ACKER, Jason Co-Investigator(s) / Trainee: FREED, Darren |
Intramural Research Grant Program | $377,997 | ||
| Clot-targeting the novel thrombolytic activity of recombinant factor X | Principal Investigator: PRYZDIAL, Ed Co-Investigator(s) / Trainee: HAO, Lihua |
Postdoctoral Fellowship Program | $164,200 | ||
| Generation of a coagulation factor-based thrombotic agent | Principal Investigator: PRYZDIAL, Ed Co-Investigator(s) / Trainee: WITT, Alexandra |
Graduate Fellowship Program | $122,000 | ||
| Modified platelet storage containers to improve quality during storage | Principal Investigator: KIZHAKKEDATHU, Jayachandran Co-Investigator(s) / Trainee: PEREYRA DOS SANTOS, Nicolas |
Graduate Fellowship Program | $122,000 | ||
| Accelerating the clinical translation of hematopoietic stem cell gene editing to correct hemoglobin disorders | Principal Investigator: MAGANTI, Harinad Co-Investigator(s) / Trainee: HANOTAUX, Justine |
Graduate Fellowship Program | $70,000 | ||
| Defining the stem cell regulatory functions of GAS6 and FTO | Principal Investigator: MAGANTI, Harinad Co-Investigator(s) / Trainee: PASALA, Ajay |
Graduate Fellowship Program | $122,000 | ||
| Assessing the relationship between red blood cell deformability and transfusion lifetime | Principal Investigator: MA, Hongshen Co-Investigator(s) / Trainee: LAMOUREUX, Erik |
Graduate Fellowship Program | $122,000 | ||
| Ice Recrystallization Inhibitors as a Glycerol Replacement in Red Blood Cell Cryopreservation | Principal Investigator: BEN, Robert Co-Investigator(s) / Trainee: WALSH, Ellyssa |
Graduate Fellowship Program | $70,000 | ||
| External validation of a prediction model for diagnosing immune thrombocytopenia | Principal Investigator: ARNOLD, Donald Co-Investigator(s) / Trainee: MAHAMAD, Syed |
Graduate Fellowship Program | $70,000 | ||
| Sexual orientation and gender identity in organ and tissue donation and transplantation: a curriculum in cultural humility | Principal Investigator: LEEIES, Murdoch Co-Investigator(s) / Trainee: COLLISTER, David, HO, Julie, DOUCETTE, Karen, FINGRUT, Warren, CHRISTIE, Emily, MACKENZIE, Lauren J., HRYMAK, Carmen, MOONEY, Owen, WHITLEY, Cameron, SHEMIE, Sam, DHANANI, Sonny, WEISS, Matthew, CARTA, Tricia, BURNS, Karen, PIQUETTE, Dominique, SHIMMIN, Carolyn, CHANDLER, Jennifer, DUNGAVELL, Sara, SUTHA, Ken, KOLTON, Mackenzie, JAKUBIEC, Brittany, LALANI, Jehan |
BloodTechNet Award Program | $49,938 | ||
| Management of critical bleeding in patients with immune thrombocytopenia | Principal Investigator: GUYATT, Gordon Co-Investigator(s) / Trainee: CHOWDHURY, Saifur |
Graduate Fellowship Program | $70,000 | ||
| Developing educational tools and resources to improve living donor care | Principal Investigator: SANDAL, Shaifali Co-Investigator(s) / Trainee: NUGUS, Peter, FORTIN, Marie-Chantal, LOBAN, Katya, BUGEJA, Ann, MAINRA, Rahul, DIPCHAND, Christine, BADENOCH, Heather |
BloodTechNet Award Program | $50,000 | ||
| Monovalent anti-FcγRI strategy in transfusion medicine | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: TUNDIDOR, Yaima |
Postdoctoral Fellowship Program | $162,400 | ||
| RBC hemolysis and cellular effector mechanisms (RHANCEM) | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: CSERTI-GAZDEWICH, Christine, PENDERGRAST,Jacob, CALLUM, Jeannie, YI, Qilong |
Intramural Research Grant Program | $399,927 | ||
| Revisiting the universal donor: Does exposure to O blood products affect patient outcomes? | Principal Investigator: ARNOLD, Donald Co-Investigator(s) / Trainee: ACKER, Jason, BUCKSTEIN, Rena, CALLUM, Jeannie, COOK, Richard, HEDDLE, Nancy, SOLH, Ziad, WEBERT, Kathryn, BARTY, Rebecca, LEBER, Brian, LALIT, Saini |
Intramural Research Grant Program | $378,365 | ||
| Innovative strategies for detection of uncharacterized platelet ligands from blood plasma and autoantibodies in blood | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: SLAVKOVIC, Sladjana |
Postdoctoral Fellowship Program | $162,400 | ||
| Fc receptor blockade in transfusion medicine | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: NI, Heyu, GUPTA, Akash, SHEHATA, Nadine, KJELDSEN-KRAGH, Jens, NEWMAN, Peter J., CSERTI-GAZDEWICH, Christine, RAVETCH, Jeffery |
Intramural Research Grant Program | $400,000 | ||
| Small molecule inhibitors of phagocytosis | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: KOTRA, Lakshmi P. |
Intramural Research Grant Program | $399,130 | ||
| Controlling coagulopathy and bleeding in a mouse model of hemorrhagic shock | Principal Investigator: SHEFFIELD, William Co-Investigator(s) / Trainee: NAZY, Ishac |
Intramural Research Grant Program | $274,854 | ||
| Biomarkers in patients with anemia-induced thrombocytopenic bleeding (BAIT): A pilot study | Principal Investigator: ARNOLD, Donald Co-Investigator(s) / Trainee: WEBERT, Kathryn, LIAW, Patricia, BERG, Tobias, HEDDLE, Nancy |
Intramural Research Grant Program | $200,000 | ||
| Evaluating transfusion medicine patterns of practice across GEMINI sites | Principal Investigator: CALLUM, Jeannie Co-Investigator(s) / Trainee: ARNOLD, Donald, VERMA, Amol, SRIVASTAVA, Siddhartha, CHENG, Calvino, ESMAIL, Tariq, DESVEAUX, Laura, TYRYSHKIN, Kathrin, KARKOUTI, Keyvan, LADHA, Karim, LI, Na, PAVENSKI, Katerina, PENDERGRAST, Jacob, PRESSEAU, Justin, SCHNEIDER, Henry, SHEHATA, Nadine, SHIH, Andrew, THIRUMURTHY, Harsha, BREHAUT, Jamie, RAZAK, Fahad, MCLCEARY, Nicola, ZUCKERMAN, Jesse |
Kenneth J. Fyke Award Program | $98,822 | ||
| Replacing plasma-derived C1 Esterase inhibitor | Principal Investigator: SHEFFIELD, William Co-Investigator(s) / Trainee: SIVANANTHAN, Sangavi |
Graduate Fellowship Program | $70,000 | ||
| Donor factors and product quality | Principal Investigator: ACKER, Jason Co-Investigator(s) / Trainee: YAZDANBAKHSH, Mahsa |
Graduate Fellowship Program | $122,000 | ||
| Preservation of red blood cells by the novel isochoric oil-sealing supercooling system | Principal Investigator: ACKER, Jason Co-Investigator(s) / Trainee: ZHAO, Yuanheng |
Postdoctoral Fellowship Program | $167,000 | ||
| Elianna Saidenberg Transfusion Medicine Trainee | Principal Investigator: LIN, Yulia Co-Investigator(s) / Trainee: RAZA, Sheharyar |
Elianna Saidenberg Transfusion Medicine Traineeship Award | $210,000 | ||
| Elianna Saidenberg Transfusion Medicine Trainee | Principal Investigator: LIN, Yulia Co-Investigator(s) / Trainee: ROTIN, Lianne |
Elianna Saidenberg Transfusion Medicine Traineeship Award | $210,000 | ||
| Elianna Saidenberg Transfusion Medicine Trainee | Principal Investigator: LIN, Yulia Co-Investigator(s) / Trainee: ARYA, Sumedha |
Elianna Saidenberg Transfusion Medicine Traineeship Award | $210,000 | ||
| Transcriptome analyses of Staphylococcus aureus grown in platelet concentrates with focus on virulence | Principal Investigator: RAMIREZ-ARCOS, Sandra Co-Investigator(s) / Trainee: DA SILVA PAREDES, Carina |
Graduate Fellowship Program | $122,000 | ||
| Fc receptor blockade related to fetal and neonatal alloimmune thrombocytopenia | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: TAWHIDI, Zoya |
Graduate Fellowship Program | $70,000 | ||
| Anemia-induced bleeding in thrombocytopenic patients with blood cancer | Principal Investigator: ARNOLD, Donald Co-Investigator(s) / Trainee: MODI, Dimpy |
Graduate Fellowship Program | $70,000 | ||
| Assessing acceptability, understanding and effectiveness of alternative screening questions for current donors | Principal Investigator: FISHER, William HAW, Jennie Co-Investigator(s) / Trainee: HAW, Jennie, GOLDMAN, Mindy, FOSTER, Terrie, O'BRIEN, Sheila, HOFKIRCHNER, Alexander |
MSM Plasma Program | $129,400 | ||
| CD71 Erythroid Cells, RBC Clearance and Sepsis in Donor - Recipient Sex- Mismatched Transfusion | Principal Investigator: ACKER, Jason Co-Investigator(s) / Trainee: LI, Wenhui |
Graduate Fellowship Program | $70,000 | ||
| Improving blood product quality | Principal Investigator: DEVINE, Dana Co-Investigator(s) / Trainee: MA, Hongshen, JOHNSON, James, D'ALESSANDRO, Angelo |
Intramural Research Grant Program | $304,462 | ||
| Demonstration of genetic blood group transition in patients undergoing ABO-mismatched allogeneic hematopoietic stem cell transplantation by peripheral blood quantitative polymerase chain reaction targeting the ABO locus – Full Study | Principal Investigator: MCGINNIS, ERIC Co-Investigator(s) / Trainee: SHIH, Andrew, WANG, Xiu Qing, STUBBINS, Ryan, HUDOBA, Monika, PETRASZKO, Tanya |
Blood Efficiency Accelerator Program | $30,000 | ||
| Hypothermic Storage as an Alternative to Irradiation of Red Cell Concentrates | Principal Investigator: ACKER, Jason Co-Investigator(s) / Trainee: CLARKE, Gwen, NAHIRNIAK, Susan, BRANDON-COATHAM, Mackenzie, OLAFSON, Carly |
Blood Efficiency Accelerator Program | $30,000 | ||
| Cold- versus room-temperature storage of platelets for bleeding in hematologic malignancy trials (CoVeRTS-HM Trial) | Principal Investigator: MACK, Johnathan Co-Investigator(s) / Trainee: TINMOUTH, Alan, FERGUSSON, Dean, SABLOFF, Mitchell |
Blood Efficiency Accelerator Program | $26,385 | ||
| A Simulation Model to Inform Best Practices for Inventory Management of Group O Negative Red Blood Cells | Principal Investigator: RUTHERFORD, Alexander Co-Investigator(s) / Trainee: BLAKE, John, SHIH, Andrew, MORRISON, Douglas, SAREMI, Alireza |
Blood Efficiency Accelerator Program | $29,500 | ||
| Red Cell Transfusion Rate and Allosensitization in Patients with End Stage Kidney Disease | Principal Investigator: ZIMMERMAN, Deborah Co-Investigator(s) / Trainee: FERGUSSON, Dean, FORSTER, Alan, KNOLL, Greg, CALLUM, Jeannie, TINMOUTH, Alan, MACK, Johnathan, CLARK, Edward, RAMSAY, Tim, PERELMAN, Iris |
Blood Efficiency Accelerator Program | $29,015.68 | ||
| Elianna Saidenberg Transfusion Medicine Trainee | Principal Investigator: ZELLER, Michelle Co-Investigator(s) / Trainee: GABARIN, Nadia |
Elianna Saidenberg Transfusion Medicine Traineeship Award | $210,000 | ||
| Determining potential policy solutions for normothermic regional perfusion in organ donation in Canada through analysis and resolution of two key ethical challenges | Principal Investigator: WEIJER, Charles Co-Investigator(s) / Trainee: BADENOCH, Heather, BASMAJI, John, BRAHMANIA, Mayur, CHANDLER, Jennifer, HEALEY, Andrew, LINGARD, Lorelei, MURPHY, Nicholas, OTT, Mary, SHEMIE, Sam, SKARO, Anton, SLESSAREV, Marat |
James Kreppner Award Program | $50,000 | ||
| Identifying biomarkers for Staphylococcus aureus contamination of platelet component | Principal Investigator: RAMIREZ-ARCOS, Sandra Co-Investigator(s) / Trainee: CHI, Sylvia Ighem |
Postdoctoral Fellowship Program | $150,000 | ||
| Rationale, development, and feasibility of a prehospital transfusion registry | Principal Investigator: NOLAN, Brodie Co-Investigator(s) / Trainee: PEDDLE, Michael, LIN, Yulia, KHANDELWAL, Aditi, MCGOWAN, Melissa, TROJANOWSKI, Jan, SHIH, Andrew |
Blood Efficiency Accelerator Program | $30,000 | ||
| Can pre-operative anemia be timely identified and optimized in patients awaiting primary arthroplasty surgery? A randomized clinical trial | Principal Investigator: GRAMMATOPOULOS, George Co-Investigator(s) / Trainee: FERGUSSON, Dean, RAMSAY, Tim, TINMOUTH, Alan, GAGNE, Sylvain, MACK, Johnathan, BELZILE, Etienne, BEALE, Paul, THAVORN, Kednapa, TOUCHIE, Donna, GERMAIN, Genevieve, LAROCHE, Vincent |
Intramural Research Grant Program | $276,081 | ||
| Development of porcine equivalent RCC and plasma units for translatable ex vivo organ perfusion research | Principal Investigator: ACKER, Jason Co-Investigator(s) / Trainee: FREED, Darren |
Intramural Research Grant Program | $121,834 |