Our Funded Research Projects

Updated April 2024

Title Principal Investigator / Supervisor Program Project Start Date Project End Date Sort ascending Total $ Awarded
Clot-targeting the novel thrombolytic activity of recombinant factor X Principal Investigator: PRYZDIAL, Ed

Co-Investigator(s) / Trainee: HAO, Lihua
Postdoctoral Fellowship Program $164,200
Novel techniques in transfusion medicine: Advancing clinical investigations and discovering new ligands of platelets Principal Investigator: BECKETT, Andrew

Co-Investigator(s) / Trainee: SHOARA, Aron
Postdoctoral Fellowship Program $164,200
Generation of a coagulation factor-based thrombotic agent Principal Investigator: PRYZDIAL, Ed

Co-Investigator(s) / Trainee: WITT, Alexandra
Graduate Fellowship Program $122,000
Modified platelet storage containers to improve quality during storage Principal Investigator: KIZHAKKEDATHU, Jayachandran

Co-Investigator(s) / Trainee: PEREYRA DOS SANTOS, Nicolas
Graduate Fellowship Program $122,000
Accelerating the clinical translation of hematopoietic stem cell gene editing to correct hemoglobin disorders Principal Investigator: MAGANTI, Harinad

Co-Investigator(s) / Trainee: HANOTAUX, Justine
Graduate Fellowship Program $70,000
Defining the stem cell regulatory functions of GAS6 and FTO Principal Investigator: MAGANTI, Harinad

Co-Investigator(s) / Trainee: PASALA, Ajay
Graduate Fellowship Program $122,000
Assessing the relationship between red blood cell deformability and transfusion lifetime Principal Investigator: MA, Hongshen

Co-Investigator(s) / Trainee: LAMOUREUX, Erik
Graduate Fellowship Program $122,000
Ice Recrystallization Inhibitors as a Glycerol Replacement in Red Blood Cell Cryopreservation Principal Investigator: BEN, Robert

Co-Investigator(s) / Trainee: WALSH, Ellyssa
Graduate Fellowship Program $70,000
External validation of a prediction model for diagnosing immune thrombocytopenia Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee: MAHAMAD, Syed
Graduate Fellowship Program $70,000
Sexual orientation and gender identity in organ and tissue donation and transplantation: a curriculum in cultural humility Principal Investigator: LEEIES, Murdoch

Co-Investigator(s) / Trainee: COLLISTER, David, HO, Julie, DOUCETTE, Karen, FINGRUT, Warren, CHRISTIE, Emily, MACKENZIE, Lauren J., HRYMAK, Carmen, MOONEY, Owen, WHITLEY, Cameron, SHEMIE, Sam, DHANANI, Sonny, WEISS, Matthew, CARTA, Tricia, BURNS, Karen, PIQUETTE, Dominique, SHIMMIN, Carolyn, CHANDLER, Jennifer, DUNGAVELL, Sara, SUTHA, Ken, KOLTON, Mackenzie, JAKUBIEC, Brittany, LALANI, Jehan
BloodTechNet Award Program $49,938
Management of critical bleeding in patients with immune thrombocytopenia Principal Investigator: GUYATT, Gordon

Co-Investigator(s) / Trainee: CHOWDHURY, Saifur
Graduate Fellowship Program $70,000
Developing educational tools and resources to improve living donor care Principal Investigator: SANDAL, Shaifali

Co-Investigator(s) / Trainee: NUGUS, Peter, FORTIN, Marie-Chantal, LOBAN, Katya, BUGEJA, Ann, MAINRA, Rahul, DIPCHAND, Christine, BADENOCH, Heather
BloodTechNet Award Program $50,000
Monovalent anti-FcγRI strategy in transfusion medicine Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: TUNDIDOR, Yaima
Postdoctoral Fellowship Program $162,400
Revisiting the universal donor: Does exposure to O blood products affect patient outcomes? Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee: ACKER, Jason, BUCKSTEIN, Rena, CALLUM, Jeannie, COOK, Richard, HEDDLE, Nancy, SOLH, Ziad, WEBERT, Kathryn, BARTY, Rebecca, LEBER, Brian, LALIT, Saini
Intramural Research Grant Program $378,365
Small molecule inhibitors of phagocytosis Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: KOTRA, Lakshmi P.
Intramural Research Grant Program $399,130
Innovative strategies for detection of uncharacterized platelet ligands from blood plasma and autoantibodies in blood Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee: SLAVKOVIC, Sladjana
Postdoctoral Fellowship Program $162,400
Fc receptor blockade in transfusion medicine Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: NI, Heyu, GUPTA, Akash, SHEHATA, Nadine, KJELDSEN-KRAGH, Jens, NEWMAN, Peter J., CSERTI-GAZDEWICH, Christine, RAVETCH, Jeffery
Intramural Research Grant Program $400,000
Controlling coagulopathy and bleeding in a mouse model of hemorrhagic shock Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: NAZY, Ishac
Intramural Research Grant Program $274,854
Biomarkers in patients with anemia-induced thrombocytopenic bleeding (BAIT): A pilot study Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee: WEBERT, Kathryn, LIAW, Patricia, BERG, Tobias, HEDDLE, Nancy
Intramural Research Grant Program $200,000
Preservation of red blood cells by the novel isochoric oil-sealing supercooling system Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: ZHAO, Yuanheng
Postdoctoral Fellowship Program $167,000
Evaluating transfusion medicine patterns of practice across GEMINI sites Principal Investigator: CALLUM, Jeannie

Co-Investigator(s) / Trainee: ARNOLD, Donald, VERMA, Amol, SRIVASTAVA, Siddhartha, CHENG, Calvino, ESMAIL, Tariq, DESVEAUX, Laura, TYRYSHKIN, Kathrin, KARKOUTI, Keyvan, LADHA, Karim, LI, Na, PAVENSKI, Katerina, PENDERGRAST, Jacob, PRESSEAU, Justin, SCHNEIDER, Henry, SHEHATA, Nadine, SHIH, Andrew, THIRUMURTHY, Harsha, BREHAUT, Jamie, RAZAK, Fahad, MCLCEARY, Nicola, ZUCKERMAN, Jesse
Kenneth J. Fyke Award Program $98,822
Replacing plasma-derived C1 Esterase inhibitor Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: SIVANANTHAN, Sangavi
Graduate Fellowship Program $70,000
Donor factors and product quality Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: YAZDANBAKHSH, Mahsa
Graduate Fellowship Program $122,000
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: LIN, Yulia

Co-Investigator(s) / Trainee: RAZA, Sheharyar
Elianna Saidenberg Transfusion Medicine Traineeship Award $210,000
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: LIN, Yulia

Co-Investigator(s) / Trainee: ROTIN, Lianne
Elianna Saidenberg Transfusion Medicine Traineeship Award $210,000
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: LIN, Yulia

Co-Investigator(s) / Trainee: ARYA, Sumedha
Elianna Saidenberg Transfusion Medicine Traineeship Award $210,000
Transcriptome analyses of Staphylococcus aureus grown in platelet concentrates with focus on virulence Principal Investigator: RAMIREZ-ARCOS, Sandra

Co-Investigator(s) / Trainee: DA SILVA PAREDES, Carina
Graduate Fellowship Program $122,000
Fc receptor blockade related to fetal and neonatal alloimmune thrombocytopenia Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: TAWHIDI, Zoya
Graduate Fellowship Program $70,000
Improving blood product quality Principal Investigator: DEVINE, Dana

Co-Investigator(s) / Trainee: MA, Hongshen, JOHNSON, James, D'ALESSANDRO, Angelo
Intramural Research Grant Program $304,462
Anemia-induced bleeding in thrombocytopenic patients with blood cancer Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee: MODI, Dimpy
Graduate Fellowship Program $70,000
CD71 Erythroid Cells, RBC Clearance and Sepsis in Donor - Recipient Sex- Mismatched Transfusion Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: LI, Wenhui
Graduate Fellowship Program $70,000
Assessing acceptability, understanding and effectiveness of alternative screening questions for current donors Principal Investigator: FISHER, William
HAW, Jennie

Co-Investigator(s) / Trainee: HAW, Jennie, GOLDMAN, Mindy, FOSTER, Terrie, O'BRIEN, Sheila, HOFKIRCHNER, Alexander
MSM Plasma Program $129,400
Demonstration of genetic blood group transition in patients undergoing ABO-mismatched allogeneic hematopoietic stem cell transplantation by peripheral blood quantitative polymerase chain reaction targeting the ABO locus – Full Study Principal Investigator: MCGINNIS, ERIC

Co-Investigator(s) / Trainee: SHIH, Andrew, WANG, Xiu Qing, STUBBINS, Ryan, HUDOBA, Monika, PETRASZKO, Tanya
Blood Efficiency Accelerator Program $30,000
Hypothermic Storage as an Alternative to Irradiation of Red Cell Concentrates Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: CLARKE, Gwen, NAHIRNIAK, Susan, BRANDON-COATHAM, Mackenzie, OLAFSON, Carly
Blood Efficiency Accelerator Program $30,000
Cold- versus room-temperature storage of platelets for bleeding in hematologic malignancy trials (CoVeRTS-HM Trial) Principal Investigator: MACK, Johnathan

Co-Investigator(s) / Trainee: TINMOUTH, Alan, FERGUSSON, Dean, SABLOFF, Mitchell
Blood Efficiency Accelerator Program $26,385
A Simulation Model to Inform Best Practices for Inventory Management of Group O Negative Red Blood Cells Principal Investigator: RUTHERFORD, Alexander

Co-Investigator(s) / Trainee: BLAKE, John, SHIH, Andrew, MORRISON, Douglas, SAREMI, Alireza
Blood Efficiency Accelerator Program $29,500
Red Cell Transfusion Rate and Allosensitization in Patients with End Stage Kidney Disease Principal Investigator: ZIMMERMAN, Deborah

Co-Investigator(s) / Trainee: FERGUSSON, Dean, FORSTER, Alan, KNOLL, Greg, CALLUM, Jeannie, TINMOUTH, Alan, MACK, Johnathan, CLARK, Edward, RAMSAY, Tim, PERELMAN, Iris
Blood Efficiency Accelerator Program $29,015.68
RBC hemolysis and cellular effector mechanisms (RHANCEM) Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: CSERTI-GAZDEWICH, Christine, PENDERGRAST,Jacob, CALLUM, Jeannie, YI, Qilong
Intramural Research Grant Program $399,927
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: ZELLER, Michelle

Co-Investigator(s) / Trainee: GABARIN, Nadia
Elianna Saidenberg Transfusion Medicine Traineeship Award $210,000
Determining potential policy solutions for normothermic regional perfusion in organ donation in Canada through analysis and resolution of two key ethical challenges Principal Investigator: WEIJER, Charles

Co-Investigator(s) / Trainee: BADENOCH, Heather, BASMAJI, John, BRAHMANIA, Mayur, CHANDLER, Jennifer, HEALEY, Andrew, LINGARD, Lorelei, MURPHY, Nicholas, OTT, Mary, SHEMIE, Sam, SKARO, Anton, SLESSAREV, Marat
James Kreppner Award Program $50,000
Identifying biomarkers for Staphylococcus aureus contamination of platelet component Principal Investigator: RAMIREZ-ARCOS, Sandra

Co-Investigator(s) / Trainee: CHI, Sylvia Ighem
Postdoctoral Fellowship Program $150,000
Rationale, development, and feasibility of a prehospital transfusion registry Principal Investigator: NOLAN, Brodie

Co-Investigator(s) / Trainee: PEDDLE, Michael, LIN, Yulia, KHANDELWAL, Aditi, MCGOWAN, Melissa, TROJANOWSKI, Jan, SHIH, Andrew
Blood Efficiency Accelerator Program $30,000
Can pre-operative anemia be timely identified and optimized in patients awaiting primary arthroplasty surgery? A randomized clinical trial Principal Investigator: GRAMMATOPOULOS, George

Co-Investigator(s) / Trainee: FERGUSSON, Dean, RAMSAY, Tim, TINMOUTH, Alan, GAGNE, Sylvain, MACK, Johnathan, BELZILE, Etienne, BEALE, Paul, THAVORN, Kednapa, TOUCHIE, Donna, GERMAIN, Genevieve, LAROCHE, Vincent
Intramural Research Grant Program $276,081
Development of porcine equivalent RCC and plasma units for translatable ex vivo organ perfusion research Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: FREED, Darren
Intramural Research Grant Program $121,834
A clinical comparison of cold-stored and room temperature-stored allogeneic platelet transfusions in bleeding adult cardiac surgery patients - A randomized multicentre pilot study (PLTS-1 study) Principal Investigator: BARTOSZKO, Justyna

Co-Investigator(s) / Trainee: CALLUM, Jeannie, DEVINE, Dana, KARKOUTI, Keyvan, KAHR, Walter, MCVEY, Mark, PEER, Miki, RAO, Vivek, ABRAHAMYAN, Lusine, LIEBERMAN, Lani, MEWHORT, Holly
Intramural Research Grant Program $242,617
Enabling next generation hematopoietic-based therapeutics and manufacturing Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: MCCOMB, Scott, JEZIERSKI, Anna, MAGALHAES, Ana, IQBAL, Umer
Intramural Research Grant Program $300,000
COVID-19 vaccination refusal and access to transplantation: an ethical conundrum. A legal analysis and a qualitative study with key stakeholders Principal Investigator: FORTIN, Marie-Chantal

Co-Investigator(s) / Trainee: CHANDLER, Jennifer, GILL, Justin, GOLDBERG, Aviva, GRUBEN, Vanessa
James Kreppner Award Program $49,952
Leveraging equity-focused implementation science to evaluate and support the re-integration of men who have sex with men into the blood donation system Principal Investigator: GOLDMAN, Mindy

Co-Investigator(s) / Trainee: VESNAVER, Elisabeth
CIHR Health System Impact Fellowship $108,500
Options for increasing plasma supply in Canada: A health economic preference and modelling study Principal Investigator: HOLLOWAY, Kelly

Co-Investigator(s) / Trainee: KENNEDY, Kevin
CIHR Health System Impact Fellowship $108,500
Synthesis and live cell imaging of ice recrystallization inhibitors in red blood cells Principal Investigator: BEN, Robert

Co-Investigator(s) / Trainee: MCMUNN, Leah
Graduate Fellowship Program $112,333