Nos projects de recherche

Disponible en anglais seulement

Mise à jour juillet 2020

Title Principal Investigator / Supervisor Program Project Start Date Project End Date Trier par ordre croissant Total $ Awarded
Development of a drug to replace IVIg, and ADCC as cause for unexplained hemolysis post-transfusion Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: ALMIZRAQ, Ruqayyah
Postdoctoral Fellowship Program $150,000.00
Anti-RBC monoclonal antibodies as a replacement for IVIg and anti-D in ITP Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: BRANCH, Donald, DUNN, Shannon
Intramural Research Grant Program $400,000.00
New platform for targeted gene editing of hematopoietic stem cells for cellular
therapy
Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: MAGANTI, Harinad
Postdoctoral Fellowship Program $150,000.00
Identification of mechanisms leading to antibody independent RBC hemolysis Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: FRIAS BOLIGAN, Kayluz
Postdoctoral Fellowship Program $150,000.00
Reducing IVIG usage by developing novel prophylaxis therapies against FNAIT Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee: PASMAN, Yfke
Postdoctoral Fellowship Program $150,000.00
PREMISE: Point-of-care hemoglobin accuracy and transfusion outcomes in non-cardiac surgery Principal Investigator: MARTEL, Guillaume

Co-Investigator(s) / Trainee: TINMOUTH, Alan, FERGUSSON, Dean, MCISAAC, Daniel, SHAW, Julie, RAMSAY, Tim, PRESSEAU, Justin, WHERRETT, Christopher, CARRIER, François-Martin, SEELY, Andrew, BRYSON, Gregory
Intramural Research Grant Program $392,974.00
Development of porcine equivalent RCC and plasma units for translatable ex vivo organ perfusion research Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: FREED, Darren
Intramural Research Grant Program $121,834.00
Revisiting the universal donor: Does exposure to O blood products affect patient outcomes? Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee: ACKER, Jason, BUCKSTEIN, Rena, CALLUM, Jeannie, COOK, Richard, HEDDLE, Nancy, SOLH, Ziad, WEBERT, Kathryn, BARTY, Rebecca, LEBER, Brian, LALIT, Saini
Intramural Research Grant Program $378,364.97
New cryosolution for stem cell-based therapeutics Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: BEN, Robert, HARPER, Marie-Ellen, CHAKRABORTY, Nilay
Intramural Research Grant Program $180,000.00
Assessing the impact of donor manufacturing characteristics on survival of transfused red blood cells Principal Investigator: TINMOUTH, Alan

Co-Investigator(s) / Trainee: ACKER, Jason, FERGUSSON, Dean, CHASSÉ, Michaël
Intramural Research Grant Program $90,935.00
Enabling next generation hematopoietic-based therapeutics and manufacturing Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: MCCOMB, Scott, JEZIERSKI, Anna, MAGALHAES, Ana, IQBAL, Umer
Intramural Research Grant Program $300,000.00
Translating novel clotting factor X function to threat thrombosis Principal Investigator: PRYZDIAL, Ed

Co-Investigator(s) / Trainee: MACVICAR, Brian, SHEFFIELD, William
Intramural Research Grant Program $369,052.00
Evaluation and improvement of cold stored platelets Principal Investigator: DEVINE, Dana

Co-Investigator(s) / Trainee: ZHAO, Hanqi (Wayne)
Graduate Fellowship Program $104,000.00
Replacement of IVIg by small molecule inhibitors of phagocytosis Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: LORIAMINI, Melika
Graduate Fellowship Program $52,000.00
McMaster Centre for Transfusion Research Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee:
Transfusion Medicine Research Program Support Award $1,150,000.00
Investigating a new class of small molecule ice recrystallization inhibitors for red blood cell cryopreservation Principal Investigator: BEN, Robert

Co-Investigator(s) / Trainee: AMPAW, Anna
Graduate Fellowship Program $104,000.00
Synthesis and live cell imaging of ice recrystallization inhibitors in red blood cells Principal Investigator: BEN, Robert

Co-Investigator(s) / Trainee: MCMUNN, Leah
Graduate Fellowship Program $52,000.00
University of Toronto QUEST Research Program Principal Investigator: CALLUM, Jeannie

Co-Investigator(s) / Trainee:
Transfusion Medicine Research Program Support Award $1,137,400.00
The mechanism of action of monoclonal antibody blends in the potential replacement of anti-D in HDFN Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: CRUZ-LEAL, Yoelys
Postdoctoral Fellowship Program $150,000.00
Donor characteristics and the quality of red cell concentrates Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: MYKHAILOVA, Olga
Postdoctoral Fellowship Program $150,000.00
The Calgary Plasma Study: feasibility of implementing source plasma donation with alternative screening eligibility criteria for men who have sex with men Principal Investigator: PRESSEAU, Justin

Co-Investigator(s) / Trainee: GOLDMAN, Mindy, O'BRIEN, Sheila, MACPHERSON, Paul, OTIS, Joanne, FOSTER, Terrie, VESNAVER, Elisabeth, GERMAIN, Marc, ROSSER, Andrew, LAPIERRE, Don, HILL, Nolan
MSM Plasma Program $399,875.00
Awareness and understanding of apheresis plasma donation and effectiveness of alternative donor screening questions for diverse gbMSM and trans populations Principal Investigator: GAHAGAN, Jacqueline

Co-Investigator(s) / Trainee: HAW, Jennie, LACHOWSKY, Nathan, DRYDEN, OmiSoore, MANNING, Eli, FOSTER, Terrie, O'BRIEN, Sheila, HACHETTE, Todd, MULLOWNEY, Mike
MSM Plasma Program $200,500.00
Assessing the acceptability and feasibility of a plasma donation program for gbMSM in Montréal from the point of view of cis and trans gbMSM, volunteers from Héma-Québec, current donors, and plasma product recipients Principal Investigator: OTIS, Joanne

Co-Investigator(s) / Trainee: GERMAIN, Marc, HAW, Jennie, MONTEITH, Kenneth, MYHAL, Geneviève, PRESSEAU, Justin, PIRNAT, Bojan, LAPIERRE, Don
MSM Plasma Program $390,970.00
Assessing acceptability, understanding and effectiveness of alternative screening questions for current donors Principal Investigator: FISHER, William

Co-Investigator(s) / Trainee: HAW, Jennie, GOLDMAN, Mindy, FOSTER, Terrie, O'BRIEN, Sheila, HOFKIRCHNER, Alexander
MSM Plasma Program $129,400.00
Novel detection strategies for new platelet ligands and anti-platelet antibodies Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee: NEVES, Miguel
Postdoctoral Fellowship Program $150,000.00
IN-TRUST: Using a transfusion database to explore the immune-modulatory impacts of blood transfusion and the clinical impacts of blood processing changes Principal Investigator: NING, Shuoyan

Co-Investigator(s) / Trainee: ARNOLD, Donald, ZELLER, Michelle, ACKER, Jason, LI, Na, HEDDLE, Nancy, HILLIS, Christopher, ROCHWERG, Bram, SYED, Summer
Intramural Research Grant Program $250,326.00
Understanding general population impact and opportunities from changes to blood donation deferral screening and criteria for men who have sex with men Principal Investigator: LACHOWSKY, Nathan

Co-Investigator(s) / Trainee: BRENNAN, David, CARD, Kiffer, DRYDEN, OmiSoore, GASPAR, Mark, GILBERT, Mark, GRACE, Daniel, KNIGHT, Rodney, LEBOUCHÉ, Bertrand, MORGAN, Jeffrey, SALWAY, Travis
MSM Research Grant Program $310,000.00
Modulation of biofilm formation, virulence, and antimicrobial resistance by Staphylococcus aureus during platelet storage Principal Investigator: RAMIREZ-ARCOS, Sandra

Co-Investigator(s) / Trainee: SAD, Subash, MAH, Thien-Fah
Intramural Research Grant Program $299,308.00
Informing the distribution of COVID-19 convalescent plasma through implementation of CONCOR-1 in British Columbia Principal Investigator: SHIH, Andrew

Co-Investigator(s) / Trainee: VASARHELYI, Krisztina, MANUSHA, Stephania Anna, STEINER, Ted, MCMASTER, Robert, DALY, Patricia, LI, Na, DOWN, Douglas, HEDDLE, Nancy, PETRASZKO, Tanya, LIOW, Eric, PAVLOVICH, Sasha, RUTHERFORD, Alexander
Blood Efficiency Accelerator Program $30,000.00
Fc receptors and IVIg in ITP Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: CSERTI-GAZDEICH, Christine, LIN, Yulia, CALLUM, Jeannie, SHOLZBERG, Michelle, NI, Heyu
Intramural Research Grant Program $400,000.00
Feasibility of implementing source plasma donation with alternative eligibility criteria for men who have sex with men Principal Investigator: PRESSEAU, Justin

Co-Investigator(s) / Trainee: GOLDMAN, Mindy, O'BRIEN, Sheila, MACPHERSON, Paul, OTIS, Joanne, GERMAIN, Marc, DEVINE, Dana, ROSSER, Andrew, LAPIERRE, Don
MSM Research Grant Program $309,950.00
TAD-POL (Transfusion-Associated-Dyspnea: Prospective observation and laboratory assessment) Principal Investigator: CSERTI-GAZDEWICH, Christine

Co-Investigator(s) / Trainee: BRANCH, Donald, LAZARUS, Alan, CALLUM, Jeannie, LIN, Yulia, PENDERGRAST, Jacob, LIEBERMAN, Lani, SHEHATA, Nadine, PAVENSKI, Katerina, SKEATE, Robert
Intramural Research Grant Program $278,027.45
Anti-GPIb mediated thrombocytopenia: Implications for IVIG and other therapies Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee: LAZARUS, Alan, BRANCH, Donald
Intramural Research Grant Program $381,491.00
Evaluating the role of donor characteristics and blood component manufacturing on the quality of red cell concentrates Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: BRANCH, Donald, CLARKE, Gwen, NAHIRNIAK, Susan
Intramural Research Grant Program $368,873.00
A Framework for Accelerated Synthesis of Trial Evidence – FAST Evidence - to assess efficacy of mesenchymal stromal cells and convalescent plasma for COVID-19 Principal Investigator: ALLAN, David

Co-Investigator(s) / Trainee: TINMOUTH, Alan, FERGUSSON, Dean, LALU, Manoj
Blood Efficiency Accelerator Program $25,000.00
Small molecule drug development of phagocytosis inhibitors Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: KOTRA, Lakshmi, P.
Intramural Research Grant Program $396,730.00
Plasma transfusion or plasma protein product infusion in a murine model of trauma Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: PRYZDIAL, Edward
Intramural Research Grant Program $238,347.00
Novel cell-surface engineering methods to increase immune-tolerance of allogenic cell transplantation Principal Investigator: KIZHAKKEDATHU, Jayachandran

Co-Investigator(s) / Trainee: MOON, Haisle
Graduate Fellowship Program $82,000.00
ACB and MSM - it's not an oxymoron: A research project that explores the importance of ACB people in MSM blood donation research Principal Investigator: DRYDEN, OmiSoore

Co-Investigator(s) / Trainee: LEE, Woo Jin Edward, NELSON, LaRon, MARSHALL, Zack, MBUAGBAW, Lawrence
MSM Research Grant Program $410,000.00
Monoclonal antibodies with anti-D like activity in amelioration of murine ITP Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: KHAN, RAMSHA
Graduate Fellowship Program $52,000.00
Investigating the mechanism of anti-CD44 antibody amelioration of IVIg-treatable disease Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: NORRIS, Peter
Graduate Fellowship Program $104,000.00
Deformability based cell sorting enabling quality control of stored red blood cells Principal Investigator: MA, Hongshen

Co-Investigator(s) / Trainee: ISLAMZADA, EMEL
Graduate Fellowship Program $52,000.00
Measurement of heavy metals in donor blood in Canada Principal Investigator: DEVINE, Dana

Co-Investigator(s) / Trainee: SERRANO, Katherine, LEVIN, Elena, MURPHY, Michael, BARAKAUSKAS, Vilte, HADJESFAMDOARI, Narges, ARRIETA, Angele, RICHARDSON-SANCHEZ, Tomas
Blood Efficiency Accelerator Award Program $29,971.00
Optimization of monoclonal anti-erythrocyte antibodies for improved immunoprophylaxis in a murine model Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: NI, Heyu
Intramural Research Grant Program $400,000.00
Virtual transfusions competency assessment Principal Investigator: VAN VLIET, Paula

Co-Investigator(s) / Trainee: DEYDEY, Kim, WESOLOWSKI, Mike
BloodTechNet Award Program $32,795.00
Support of HLA laboratory directors in-training for rotations in specialized laboratories Principal Investigator: WAGNER, Eric

Co-Investigator(s) / Trainee: KEOWN, Paul, LIWSKI, Robert, CAMPBELL, Patricia, BERKA, Noureddine, WANG, Jinguo, MOSTAFA, Ahmed, CHEE-LOONG, Saw, RICHARD, Lucie, CHARGÉ, Sophie, DHARSEE, Fatima
BloodTechNet Award Program $8,490.00
Development of internet modules for serology curriculum delivery Principal Investigator: YAN, Matthew

Co-Investigator(s) / Trainee: PENDERGRAST, Jacob, TAIT, Gordon
BloodTechNet Award Program $35,500.00
Synthesis of carbohydrate derivatives for the improvement of red blood cell storage Principal Investigator: BEN, Robert

Co-Investigator(s) / Trainee: MEYER, Julia
Graduate Fellowship Program $82,000.00
Canadian cord blood banking: Legal and policy responses Principal Investigator: CAULFIELD, Timothy

Co-Investigator(s) / Trainee: MURDOCH, Blake MARCON, Alessandro
James Kreppner Award Program $50,000.00
New solution for cord blood unit preservation Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: KAUSHAL, Richa
Graduate Fellowship Program $52,000.00