Our Funded Research Projects

Updated April 2024

Title Sort ascending Principal Investigator / Supervisor Program Project Start Date Project End Date Total $ Awarded
Estimating the probability of HIV risk in MSM donor policies through biobehavioural and mathematical modelling studies Principal Investigator: HART, Trevor

Co-Investigator(s) / Trainee: LAMBERT, Gilles, GRACE, Daniel, BAUER, Greta, MOORE, David, COX, Joseph, LACHOWSKY, Nathan, MISHRA, Sharmistha, BRENNAN, David, TAN, Darrell, SKAKOON-SPARLING, Shayna
MSM Research Grant Program 452500.0
Establishing national best practices for out-of-hospital blood transfusion: A collaboration of the Canadian Prehospital and Transport Transfusion (CAN-PATT) network Principal Investigator: NOLAN, Brodie

Co-Investigator(s) / Trainee: TROJANOWSKI, Jan, SHIH, Andrew, GREENE, Adam, EVANS, Rob, MULVEY, Jamin, CHANG, Eddie, NAHIRNIAK, Susan, PEARSON, Dallas, PROKOPCHUK-GAUK, Oksana, MARTIN, Doug, MUSUKA, Charles, SEIDL, Cindy, PEDDLE, Michael, LIN, Yulia, SMITH, Justin, MACDONALD, Scott, RICHARDS, Lindsay, FARRELL, Michael, KHANDELWAL, Aditi, CALLUM, Jeannie
Blood Efficiency Accelerator Program 30000.0
Enabling next generation hematopoietic-based therapeutics and manufacturing Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: MCCOMB, Scott, JEZIERSKI, Anna, MAGALHAES, Ana, IQBAL, Umer
Intramural Research Grant Program 300000.0
Elucidation of the mechanism of IVIG-associated hemolysis Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: PENDERGRAST, Jacob , CSERTI-GAZDEWICH, Christine , SHEHATA, Nadine , PAVENSKI, Katerina , LAU, Wendy , CALLUM, Jeannie , LIN, Yulia , LIEBERMAN, Lani , HANNACH, Barbara
Intramural Research Grant Program 393712.0
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: LAU, Wendy

Co-Investigator(s) / Trainee: TORDON, Bryan
Elianna Saidenberg Transfusion Medicine Traineeship Award 210000.0
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: LAU, Wendy

Co-Investigator(s) / Trainee: VANDERMEULEN, Heather
Elianna Saidenberg Transfusion Medicine Traineeship Award 210000.0
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: SHIH, Andrew

Co-Investigator(s) / Trainee: TAPLEY, Laura
Elianna Saidenberg Transfusion Medicine Traineeship Award 105000.0
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: ZELLER, Michelle

Co-Investigator(s) / Trainee: GABARIN, Nadia
Elianna Saidenberg Transfusion Medicine Traineeship Award 210000.0
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: LIN, Yulia

Co-Investigator(s) / Trainee: ARYA, Sumedha
Elianna Saidenberg Transfusion Medicine Traineeship Award 210000.0
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: LIN, Yulia

Co-Investigator(s) / Trainee: ROTIN, Lianne
Elianna Saidenberg Transfusion Medicine Traineeship Award 210000.0
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: LIN, Yulia

Co-Investigator(s) / Trainee: RAZA, Sheharyar
Elianna Saidenberg Transfusion Medicine Traineeship Award 210000.0
Donor factors and product quality Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: YAZDANBAKHSH, Mahsa
Graduate Fellowship Program 122000.0
Donor characteristics and the quality of red cell concentrates Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: MYKHAILOVA, Olga
Postdoctoral Fellowship Program 165000.0
DNA aptamers for detection of red blood cells destined for rapid post-transfusion clearance Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: DONKOR, David
Postdoctoral Fellowship Program 150000.0
Development of porcine equivalent RCC and plasma units for translatable ex vivo organ perfusion research Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: FREED, Darren
Intramural Research Grant Program 121834.0
Development of novel blood vessel and organ sealants for blood conservation in surgical practice Principal Investigator: BROOKS, Don

Co-Investigator(s) / Trainee: DU, Caigan , HSIANG, York N. , KIZHAKKEDATHU, Jayachandran N. , KO, Frank K.
Canadian Blood Services-CIHR Partnership Operating Grant Program 240996.0
Development of internet modules for serology curriculum delivery Principal Investigator: YAN, Matthew

Co-Investigator(s) / Trainee: PENDERGRAST, Jacob, TAIT, Gordon
BloodTechNet Award Program 35500.0
Development of a small molecule-based stem and progenitor expansion protocol to accelerate engraftment after cord blood transplantation Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: MANESIA, Javed
Postdoctoral Fellowship Program 101200.0
Development of a small molecule cocktail for the expansion of cord blood stem cells Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: BLAKE, John, AUDET, Julie
Intramural Research Grant Program 237600.0
Development of a drug to replace IVIg, and ADCC as cause for unexplained hemolysis post-transfusion Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: ALMIZRAQ, Ruqayyah
Postdoctoral Fellowship Program 165000.0
Developing educational tools and resources to improve living donor care Principal Investigator: SANDAL, Shaifali

Co-Investigator(s) / Trainee: NUGUS, Peter, FORTIN, Marie-Chantal, LOBAN, Katya, BUGEJA, Ann, MAINRA, Rahul, DIPCHAND, Christine, BADENOCH, Heather
BloodTechNet Award Program 50000.0
Developing a Canadian policy on the responsible use of umbilical cord blood for proven indications in regenerative therapy Principal Investigator: ALLAN, David

Co-Investigator(s) / Trainee: HUTTON, Brian, CAULFIELD, Timothy
Kenneth J. Fyke Award Program 100000.0
Determining potential policy solutions for normothermic regional perfusion in organ donation in Canada through analysis and resolution of two key ethical challenges Principal Investigator: WEIJER, Charles

Co-Investigator(s) / Trainee: BADENOCH, Heather, BASMAJI, John, BRAHMANIA, Mayur, CHANDLER, Jennifer, HEALEY, Andrew, LINGARD, Lorelei, MURPHY, Nicholas, OTT, Mary, SHEMIE, Sam, SKARO, Anton, SLESSAREV, Marat
James Kreppner Award Program 50000.0
Design and implementation of circulatory oxygen therapeutics derived from human hemoglobin by improved systematic chemical coupling and cross-linking Principal Investigator: KLUGER, Ronald

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership Operating Grant Program 192039.0
Dengue virus replication by anucleate cells: impact on pathogen reduction efficacy Principal Investigator: PRYZDIAL, Ed

Co-Investigator(s) / Trainee: FELGENHAUER, Ulrike
Graduate Fellowship Program 52000.0
Demonstration of genetic blood group transition in patients undergoing ABO-mismatched hematopoietic stem cell transplantation by peripheral blood quantitative polymerase chain reaction targeting the ABO locus Principal Investigator: SHIH, Andrew

Co-Investigator(s) / Trainee: LAZO-LANGER, Alejandro, D'SOUZA, David, CALLUM, Jeannie, LEUNG, Eric, CHIN-YEE, Ian
Blood Efficiency Accelerator Program 15990.0
Demonstration of genetic blood group transition in patients undergoing ABO-mismatched allogeneic hematopoietic stem cell transplantation by peripheral blood quantitative polymerase chain reaction targeting the ABO locus – Full Study Principal Investigator: MCGINNIS, ERIC

Co-Investigator(s) / Trainee: SHIH, Andrew, WANG, Xiu Qing, STUBBINS, Ryan, HUDOBA, Monika, PETRASZKO, Tanya
Blood Efficiency Accelerator Program 30000.0
Deformability based cell sorting enabling quality control of stored red blood cells Principal Investigator: MA, Hongshen

Co-Investigator(s) / Trainee: ISLAMZADA, Emel
Graduate Fellowship Program 112333.0
Defining the stem cell regulatory functions of GAS6 and FTO Principal Investigator: MAGANTI, Harinad

Co-Investigator(s) / Trainee: PASALA, Ajay
Graduate Fellowship Program 52000.0
Defining the components of transfusable plasma that reduce bleeding Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: PRYZDIAL, Edward, NI, Heyu
Intramural Research Grant Program 218230.0
Defining disease mechanisms in Immune Thrombocytopenia (ITP) and their association with clinical outcomes Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee: COOK, Richard J., NAZY, Ishac
Canadian Blood Services-CIHR Partnership Operating Grant Program 317469.0
Data sharing with CBMTG registry Principal Investigator: ALLAN, David

Co-Investigator(s) / Trainee: PAULSON, Kristjan
Small Project Funding Program 15000.0
COVID-19 vaccination refusal and access to transplantation: an ethical conundrum. A legal analysis and a qualitative study with key stakeholders Principal Investigator: FORTIN, Marie-Chantal

Co-Investigator(s) / Trainee: CHANDLER, Jennifer, GILL, Justin, GOLDBERG, Aviva, GRUBEN, Vanessa
James Kreppner Award Program 49952.0
Controlling coagulopathy and bleeding in a mouse model of hemorrhagic shock Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: NAZY, Ishac
Intramural Research Grant Program 274854.0
Cold- versus room-temperature storage of platelets for bleeding in hematologic malignancy trials (CoVeRTS-HM Trial) Principal Investigator: MACK, Johnathan

Co-Investigator(s) / Trainee: TINMOUTH, Alan, FERGUSSON, Dean, SABLOFF, Mitchell
Blood Efficiency Accelerator Program 26385.0
Code sepsis: defining and translating optimal resuscitation and care for children with septic shock Principal Investigator: PARKER, Melissa

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership New Investigator Program 300000.0
Clot-targeting the novel thrombolytic activity of recombinant factor X Principal Investigator: PRYZDIAL, Ed

Co-Investigator(s) / Trainee: HAO, Lihua
Postdoctoral Fellowship Program 164200.0
Characterization of the role of MSI2 in human hematopoietic stem cell self-renewal Principal Investigator: HOPE, Kristin

Co-Investigator(s) / Trainee: RENTAS, Stefan
Graduate Fellowship Program 100000.0
Characterization of the hematopoietic reconstitution enhancing activity of osteoblasts derived from human mesenchymal stromal cells Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: CAMPBELL, Pearl , GARNIER, Alain
Canadian Blood Services-CIHR Partnership Operating Grant Program 320504.0
Cellular therapy to improve CD4+ T-Cell responses in humanized mice infected with HIV-1: adoptive transfer of CD4+ T-cells lacking s-Src activity Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: McCARTHY, Stephen
Graduate Fellowship Program 96000.0
CD71 Erythroid Cells, RBC Clearance and Sepsis in Donor - Recipient Sex- Mismatched Transfusion Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: LI, Wenhui
Graduate Fellowship Program 70000.0
Canadians’ attitudes and opinions regarding cardiac donation after cardiocirculatory death: A mixed-methods study Principal Investigator: BALL, Ian

Co-Investigator(s) / Trainee: WEISS, Matt, D'ARAGON, Fred, PARSONS LEIGH, Jenna, HONARMAND, Kimia, BASMAJI, John, SIBBALD, Robert
Kenneth J. Fyke Award Program 95929.0
Canadian cord blood banking: Legal and policy responses Principal Investigator: CAULFIELD, Timothy

Co-Investigator(s) / Trainee: MURDOCH, Blake, MARCON, Alessandro
James Kreppner Award Program 50000.0
Can pre-operative anemia be timely identified and optimized in patients awaiting primary arthroplasty surgery? A randomized clinical trial Principal Investigator: GRAMMATOPOULOS, George

Co-Investigator(s) / Trainee: FERGUSSON, Dean, RAMSAY, Tim, TINMOUTH, Alan, GAGNE, Sylvain, MACK, Johnathan, BELZILE, Etienne, BEALE, Paul, THAVORN, Kednapa, TOUCHIE, Donna, GERMAIN, Genevieve, LAROCHE, Vincent
Intramural Research Grant Program 276081.0
Blood utilization epidemiological profile to evaluate appropriate use (BLUE) Principal Investigator: ZELLER, Michelle

Co-Investigator(s) / Trainee: ARNOLD, Donald, WEBERT, Kathryn, HEDDLE, Nancy, NING, Shuoyan, BARTY, Rebecca
Blood Efficiency Accelerator Program 29964.0
Blood product demand forecast modeling using clinical predictors Principal Investigator: DOWN, Douglas

Co-Investigator(s) / Trainee: BLAKE, John , TRIFUNOV, Rick, COURTNEY, Thomas, HEDDLE, Nancy, CHIANG, Fei, LI, Na
Blood Efficiency Accelerator Program 30000.0
Blood and stem cell donation for men who have sex with men in Canada: A toolkit for healthcare professionals Principal Investigator: FINGRUT, Warren

Co-Investigator(s) / Trainee: GOLDMAN, Mindy, SHIH, Andrew, ELMOAZZEN, Heidi, ALLAN, David, PETRASZKO, Tanya, YAN, Matthew, COUPAL, Dylan, SEGALL, Romy, CHOWDHURY, Fuad, CAI, Helen, KUMAR, Shamini Vijaya, TRAADE, Daniel, ROSENFELD, Aaron, KAVEH, Farrokhi
BloodTechNet Award Program 20000.0
Biomarkers in patients with anemia-induced thrombocytopenic bleeding (BAIT): A pilot study Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee: WEBERT, Kathryn, LIAW, Patricia, BERG, Tobias, HEDDLE, Nancy
Intramural Research Grant Program 200000.0
Better blood transfusion - Phase two Principal Investigator: O'REILLY, Clare

Co-Investigator(s) / Trainee: PARKE, Graham, MORRISON, Douglas, CHIPPERFIELD, Kate, EVELEIGH, Shari, WILSON, Sophie
BloodTechNet Award Program 5250.0
Awareness and understanding of apheresis plasma donation and effectiveness of alternative donor screening questions for diverse gbMSM and trans populations Principal Investigator: GAHAGAN, Jacqueline

Co-Investigator(s) / Trainee: HAW, Jennie, LACHOWSKY, Nathan, DRYDEN, OmiSoore, MANNING, Eli, FOSTER, Terrie, O'BRIEN, Sheila, HACHETTE, Todd, MULLOWNEY, Mike
MSM Plasma Program 200500.0