Improving a quality test for cord blood samples

Thursday, February 27, 2020 Dr. Geraldine Walsh

Cord blood — the blood left in the umbilical cord after a baby is born — is a rich and important source of stem cells for transplantation. Stem cell transplants are used to treat more than 80 diseases and disorders, including blood cell cancers such as leukemia. The national Canadian Blood Services’ Cord Blood Bank collects, processes and freezes cord blood units. These units are available to any patient worldwide who needs a stem cell transplant and finds a match in the bank. 

Recent research conducted by the Centre for Innovation and Canadian Blood Services Cord Blood Bank and stem cell manufacturing sought to improve pre-transplant quality tests of thawed cord blood samples. These tests are important as they are used to make decisions about whether the cord blood unit will be suitable for transplantation.

The study, “Overcoming the deceptively low viability of CD45+ cells in thawed cord blood unit segments” was published in November 2019 in Vox Sanguinis.  

The study findings suggest ways to improve the quality test procedure so that the results produced better reflect the quality of the cord blood unit to be transplanted. This could increase the number of cord blood units that can be released for transplantation by reducing the number of cord blood units that fail quality tests.

To learn more about the study, read our latest Research Unit.

Canadian Blood Services – Driving world-class innovation

Through discovery, development and applied research, Canadian Blood Services drives world-class innovation in blood transfusion, cellular therapy and transplantation—bringing clarity and insight to an increasingly complex healthcare future. Our dedicated research team and extended network of partners engage in exploratory and applied research to create new knowledge, inform and enhance best practices, contribute to the development of new services and technologies, and build capacity through training and collaboration. Find out more about our research impact

The opinions reflected in this post are those of the author and do not necessarily reflect the opinions of Canadian Blood Services nor do they reflect the views of Health Canada or any other funding agency.


Related blog posts

Friday, July 19, 2019
Obinna Okwelume

Dr. Nicolas Pineault speaks about his passion for stem cell research, and the exciting new projects he’s currently engaged in.

Wednesday, May 11, 2016
Jenny Ryan

Dr. Pineault and his team are working on a cellular therapy to improve engraftment (the process through which new blood-forming cells start to develop in the patient) following cord blood stem cell transplantation.

Wednesday, July 12, 2017
Jenny Ryan

July marks Cord Blood Awareness Month in certain places around the world. In homage to this important campaign we collected a few related stories from the RED archives and share a bit more information about why Cord Blood matters. Cord blood stem cells can be used in the treatment of more than 80...