Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Manufacturing method affects mitochondrial DNA release and extracellular vesicle composition in stored red blood cells Bakkour S, Acker JP, Chafets DM, Inglis HC, Norris PJ, Lee TH, Busch MP 2016 Vox Sang View Researchers Basic research
Transfusion of fresher vs older red blood cells in hospitalized patients: a systematic review and meta-analysis Alexander PE, Barty R, Fei Y, Vandvik PO, Pai M, Siemieniuk RA, Heddle NM, Blumberg N, McLeod SL, Liu J, Eikelboom JW, Guyatt GH 2016 Blood View Researchers Clinical research
Using simulation for strategic blood supply chain design in the Canadian prairies Blake J, McTaggart K 2016 Proceedings of the 6th International Conference on SIMULTECH View Blood operators New or improved product or process
Comments on: Bernardo et al. 2016 (Blood)Working together to block alloimmunization Stowell SR 2016 Blood View Researchers Basic research
ResearchUnit: Data mining: digging for deeper understanding of blood components and transfusion outcomes Heddle NM, Acker JP 2016 Blood.ca website View Other Other
Strain-promoted azide-alkyne cycloaddition for protein-protein coupling in the formation of a bis-hemoglobin as a copper-free oxygen carrier Singh S, Dubinsky-Davidchik IS, Kluger R 2016 Org Biomol Chem View Researchers Basic research
Alleviation of gram-negative bacterial lung inflammation by targeting HECTD2 Kapur R, Semple JW 2016 Ann Transl Med View Researchers Basic research
Dengue virus persists and replicates during storage of platelet and red blood cell units Sutherland MR, Simon AY, Serrano K, Schubert P, Acker JP, Pryzdial ELG 2016 Transfusion View Researchers Basic research
Effects of methoxypoly (Ethylene glycol) mediated immunocamouflage on leukocyte surface marker detection, cell conjugation, activation and alloproliferation Kyluik-Price DL, Scott MD 2016 Biomaterials View Researchers Basic research
Evaluating the "family veto" of consent for organ donation Toews M, Caulfield T 2016 CMAJ View Health care providers Other
Introducing the red cell storage lesion Chen D, Serrano K, Devine DV 2016 ISBT Sci Ser View Blood operators Basic research
Myasthenia gravis treated with autologous hematopoietic stem cell transplantation Bryant A, Atkins H, Pringle C, Allan D, Anstee G, Bence-Bruckler I, Hamelin L, Hodgins M, Hopkins HS, Huebsch L, McDiarmid S, Sabloff M, Sheppard D, Tay J, Bredeson C 2016 JAMA Neurol View Researchers Clinical research
Plasma and cryoprecipitate for transfusion Stanworth SJ, Tinmouth AT 2016 Rossi's Principles of Transfusion Medicine View Researchers Basic research
Thymic-derived tolerizing dendritic cells are upregulated in the spleen upon treatment with intravenous immunoglobulin in a murine model of immune thrombocytopenia Kapur R, Aslam R, Kim M, Guo L, Ni H, Segel GB, Semple JW 2016 Platelets View Researchers Basic research
Corticosteroids compared with intravenous immunoglobulin for the treatment of immune thrombocytopenia in pregnancy Sun D, Shehata N, Ye XY, Gregorovich S, De France B, Arnold DM, Shah PS, Malinowski AK 2016 Blood View Researchers Clinical research
Impact of informing donors of low ferritin results Goldman M, Uzicanin S, Scalia J, Scalia V, O'Brien SF 2016 Transfusion View Blood operators Clinical research
Monovalent Fc receptor blockade by an anti-Fc? receptor/albumin fusion protein ameliorates murine ITP with abrogated toxicity Yu X, Menard M, Prechl J, Bhakta V, Sheffield WP, Lazarus AH 2016 Blood View Researchers Basic research
Platelets and platelet adhesion molecules: novel mechanisms of thrombosis and anti-thrombotic therapies Xu XR, Carrim N, Neves MAD, McKeown T, Stratton TW, Coelho RMP, Lei X, Chen P, Xu J, Dai X, Li BX, Ni H 2016 Thromb J View Health care providers Clinical research
Transfusion-related alloimmunization in children: epidemiology and effects of chemotherapy Solh Z, Athale U, Arnold DM, Cook RJ, Foley R, Heddle NM 2016 Vox Sang View Health care providers Clinical research
Effects of pathogen reduction systems on platelet microRNAs, mRNAs, activation, and function Osman A, Hitzler WE, Meyer CU, Landry P, Corduan A, Laffont B, Boilard E, Hellstern P, Vamvakas EC, Provost P 2015 Platelets View Researchers Basic research
Improved Prediction of CD34+ Cell Yield before Peripheral Blood Hematopoietic Progenitor Cell Collection Using a Modified Target Value–Tailored Approach Sheppard D, Tay J, Palmer D, Xenocostas A, Doulaverakis C, Huebsch L, McDiarmid S, Tinmouth A, Mallick R, Martin L, Birch P, Hamelin L, Allan D, Bredeson C 2015 Biol Blood Marrow Transplant View Health care providers New or improved product or process
Plasma and Plasma Protein Product Transfusion: A Canadian Blood Services Centre for Innovation Symposium Zeller MP, Al-Habsi KS, Golder M, Walsh GM, Sheffield WP 2015 Transfus Med Rev View Health care providers Other
Reduced deformability of parasitized red blood cells as a biomarker for anti-malarial drug efficacy Deng X, Duffy SP, Myrand-Lapierre M-E, Matthews K, Santoso AT, Du Y-L, Ryan KS, Ma H 2015 Malar J View Researchers New or improved product or process
BK virus prophylaxis with levofloxacin--reply Gill JS, Knoll GA, Humar A 2015 JAMA View Other Other
Clinical effects of blood donor characteristics in transfusion recipients: protocol of a framework to study the blood donor-recipient continuum Chasse M, McIntyre L, Tinmouth A, Acker J, English SW, Knoll G, Forster A, Shehata N, Wilson K, van Walraven C, Ducharme R, Fergusson DA 2015 BMJ Open View Researchers Other
Determining the Volume of Additive Solution and Residual Plasma in Whole Blood Filtered and Buffy Coat Processed Red Cell Concentrates Jordan A, Acker J 2015 Transfus Med Hemother View Researchers New or improved product or process
Maternal anti-platelet beta-3 integrins impair angiogenesis and cause intracranial hemorrhage Yougbaré I, Lang S, Yang H, Chen P, Zhao X, Tai W-S, Zdravic D, Vadasz B, Li C, Piran S, Marshall A, Zhu G, Tiller H, Killie MK, Boyd S, Leong-Poi H, Wen X-Y, Skogen B, Adamson SL, Freedman J, Ni H 2015 J Clin Invest View Researchers Basic research
Intermittent bacteremia detected in an asymptomatic apheresis platelet donor with repeat positive culture for Escherichia coli: a case report Ramirez-Arcos S, Alport T, Goldman M 2015 Transfusion View Blood operators Clinical research
Platelets and platelet alloantigens: lessons from human patients and animal models of fetal and neonatal alloimmune thrombocytopenia Vadasz B, Chen P, Yougbare I, Zdravic D, Li J, Li C, Carrim N, Ni H 2015 Genes Dis View Researchers Other
Virtual screen for repurposing approved and experimental drugs for candidate inhibitors of EBOLA virus infection Veljkovic V, Loiseau PM, Figadere B, Glisic S, Veljkovic N, Perovic VR, Cavanaugh DP, Branch DR 2015 F1000Res View Researchers Basic research
A systematic review of definitions and reporting of bleeding outcome measures in haemophilia Chai-Adisaksopha C, Hillis C, Thabane L, Iorio A 2015 Haemophilia View Health care providers Clinical research
Alloimmune Red Blood Cell Antibodies: Prevalence and Pathogenicity in a Canadian Prenatal Population Zwingerman R, Jain V, Hannon J, Zwingerman N, Clarke G 2015 J Obstet Gynaecol Can View Health care providers Clinical research
Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia Li J, van der Wal DE, Zhu G, Xu M, Yougbare I, Ma L, Vadasz B, Carrim N, Grozovsky R, Ruan M, Zhu L, Zeng Q, Tao L, Zhai Z-m, Peng J, Hou M, Leytin V, Freedman J, Hoffmeister KM, Ni H 2015 Nat Commun View Researchers Basic research
Haematological problems in obstetrics Rodger M, Sheppard D, Gandara E, Tinmouth A 2015 Best Pract Res Clin Obstet Gynaecol View Health care providers Other
Public Perceptions of Pathogen Reduction Technology in the Canadian Donor Blood Supply Gray N, Newbold KB, Lane SJ, Heddle NM, Webert K, Eyles J 2015 ISBT Sci Ser View Blood operators Other
The efficacy and safety of heparin in patients with sepsis: a systematic review and metaanalysis Zarychanski R, Abou-Setta AM, Kanji S, Turgeon AF, Kumar A, Houston DS, Rimmer E, Houston BL, McIntyre L, Fox-Robichaud AE, Hebert P, Cook DJ, Fergusson DA 2015 Crit Care Med View Health care providers Clinical research
The prevalence of anti-K in Canadian prenatal patients Goldman M, Lane D, Webert K, Fallis R 2015 Transfusion View Health care providers Clinical research
Western immunoblotting as a new tool for investigating direct antiglobulin test-negative autoimmune hemolytic anemias Bloch EM, Sakac D, Branch HA, Cserti-Gazdewich C, Pendergrast J, Pavenski K, Branch DR 2015 Transfusion View Health care providers New or improved product or process
A monoclonal antibody with anti-D–like activity in murine immune thrombocytopenia requires Fc domain function for immune thrombocytopenia ameliorative effects Yu X, Menard M, Seabright G, Crispin M, Lazarus AH 2015 Transfusion View Researchers Basic research
Bleeding complications from the direct oral anticoagulants Sholzberg M, Pavenski K, Shehata N, Cserti-Gazdewich C, Lin Y 2015 BMC Hematol View Health care providers Clinical research
Costs and benefits of non-invasive fetal RhD determination Teitelbaum L, Metcalfe A, Clarke G, Parboosingh JS, Wilson RD, Johnson JM 2015 Ultrasound Obstet Gynecol View Health care providers New or improved product or process
Developing Educational Resources to Advance Umbilical Cord Blood Banking and Research: A Canadian Perspective Pereira Beak C, Chargé SB, Isasi R, Knoppers BM 2015 J Obstet Gynaecol Can View Other Other
Platelet MicroRNAs: An Overview Dahiya N, Sarachana T, Vu L, Becker KG, Wood WH, Zhang Y, Atreya CD 2015 Transfus Med Rev View Researchers Basic research
Splitting versus lumping: reconsidering the definition of transfusion-related acute lung injury Webert KE 2015 Transfusion View Health care providers Clinical research
[Influence of Anticoagulants on Detection of ITP Platelet-Specific Autoantibodies and Relationship of Autoantibody Types with Glucocorticoid Efficacy] Chen Y, Ge J, Ruan M, Zhu L-Y, Zeng Q-S, Xia R-X, Ni H 2015 Zhongguo shi yan xue ye xue za zhi View Researchers Basic research
Differences in rat and human erythrocytes following blood component manufacturing: the effect of additive solutions da Silveira Cavalcante L, Acker JP, Holovati J 2015 Transfus Med Hemother View Blood operators Basic research
Mesenchymal stromal cells derived from various tissues: Biological, clinical and cryopreservation aspects Marquez-Curtis LA, Janowska-Wieczorek A, McGann LE, Elliott JAW 2015 Cryobiology View Researchers Other
Mortality outcomes in patients receiving direct oral anticoagulants: a systematic review and meta-analysis of randomized controlled trials Chai-Adisaksopha C, Hillis C, Isayama T, Lim W, Iorio A, Crowther M 2015 J Thromb Haemost View Health care providers Clinical research
Progress in RNAi-mediated Molecular Therapy of Acute and Chronic Myeloid Leukemia Landry B, Valencia-Serna J, Gul-Uludag H, Jiang X, Janowska-Wieczorek A, Brandwein J, Uludag H 2015 Mol Ther Nucleic Acids View Researchers Other
A clinical governance framework for blood services Williamson LM, Benjamin RJ, Devine DV, Katz LM, Pink J, for the Alliance of Blood Operators Medical Directors Group 2015 Vox Sang View Blood operators Other