Our Research Publications

Updated August 2025

Title Authors Year Journal Link to Article Intended Audience Purpose
Clinical Practice Guidelines From the Association for the Advancement of Blood and Biotherapies (AABB): COVID-19 Convalescent Plasma Estcourt LJ, Cohn CS, Pagano MB, Iannizzi C, Kreuzberger N, Skoetz N, Allen ES, Bloch EM, Beaudoin G, Casadevall A, Devine DV, Foroutan F, Gniadek TJ, Goel R, Gorlin J, Grossman BJ, Joyner MJ, Metcalf RA, Raval JS, Rice TW, Shaz BH, Vassallo RR, Winters JL, Tobian AAR 2022 Ann Intern Med View Health care providers Benchmarking and standard setting
How do we decide how representative our donors are for public health surveillance? O'Brien SF, Drews SJ, Lewin A, Russell A, Davison K, Goldman M, International Society for Blood Transfusion Transfusion Transmitted Infectious Disease Working Party Surveillance Risk Assessment Policy Sub-group 2022 Transfusion View Researchers Benchmarking and standard setting
GRADE guidance 35: update on rating imprecision for assessing contextualized certainty of evidence and making decisions Schünemann HJ, Neumann I, Hultcrantz M, Brignardello-Petersen R, Zeng L, Murad MH, Izcovich A, Morgano GP, Baldeh T, Santesso N, Cuello CG, Mbuagbaw L, Guyatt G, Wiercioch W, Piggott T, De Beer H, Vinceti M, Mathioudakis AG, Mayer MG, Mustafa R, Filippini T, Iorio A, Nieuwlaat R, Marcucci M, Coello PA, Bonovas S, Piovani D, Tomlinson G, Akl EA 2022 J Clin Epidemiol View Researchers Clinical research
Cold-stored platelets are effective in an in vitro model of massive transfusion protocol assessed by rotational thromboelastometry Zhao HQ, Serrano K, Culibrk B, Chen Z, Devine DV 2022 Transfusion View Researchers New or improved product or process
The timing of gamma irradiation and its effect on cell-free and microvesicle-bound hemoglobin. The BEST collaborative study William N, Bicahlo B, Hansen A, de Korte D, Acker JP, Biomedical Excellence for Safer Transfusion Collaborative 2022 Transfusion View Researchers Basic research
Circulaire d'information utilisation de composants sanguins humains: Concentrés plaquettaires à pathogènes inactivés Stewart T 2022 Blood.ca website View Health care providers Benchmarking and standard setting
Exploring the reasons for low pertussis vaccine effectiveness in Ontario, Canada, 2006–2008: a Canadian Immunization Research Network study Hughes SL, Kwong JC, Schwartz KL, Chen C, Johnson C, Li Y, Marchand-Austin A, Bolotin S, Jamieson FB, Drews SJ, Russell ML, Svenson LW, Mahmud SM, Crowcroft NS 2022 Can J Public Health View Regulators Clinical research
Lessons Learned from the COVID-19 Pandemic and How Blood Operators Can Prepare for the Next Pandemic Drews SJ, O’Brien SF 2022 Viruses View Blood operators New or improved product or process
A critical contribution in a time of crisis: Examining motivations and deterrents to COVID-19 convalescent plasma donation and future donation intentions among prospective Canadian donors Holloway K, Campbell C, Ali R, Huyer LD, Hart D, Haw J, Brennenstuhl S, Grundy Q 2022 Transfus Med View Researchers Ethical, legal & social implications research
Hypoxia and low temperature upregulate transferrin to induce hypercoagulability at high altitude Li M, Tang X, Liao Z, Shen C, Cheng R, Fang M, Wang G, Li Y, Tang S, Xie L, Zhang Z, Kamau PM, Mwangi J, Lu Q, Li Y, Wang Y, MacKeigan DT, Cerenzia EG, Ni H, Lai R 2022 Blood View Researchers Basic research
RE: A better normal in Canada will need a better detection system for emerging and re-emerging respiratory pathogens O'Brien S, Goldman M, Drews S 2022 CMAJ View Researchers Clinical research
Assessment of bacterial growth in leukoreduced cold-stored whole blood supports overnight hold at room temperature prior to filtration: A pilot study Ramirez-Arcos S, Kou Y, Kumaran D, Culibrk B, Stewart T, Schubert P, McTaggart K 2022 Vox Sang View Researchers New or improved product or process
Contamination of platelet concentrates with Staphylococcus aureus induces significant modulations in platelet functionality Yousuf B, Pasha R, Pineault N, Ramirez-Arcos S 2022 Vox Sang View Researchers Basic research
Heterogeneity of Vaccine-Induced Immune Thrombotic Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination and Safety of Second Vaccination with BNT162b2 Lindhoff-Last E, Schoenborn L, Piorkowski M, Herold J, Greinacher A, Sheppard JA, Warkentin TE 2022 Thromb Haemost View Researchers Clinical research
Blood unit segments accurately represent the biophysical properties of red blood cells in blood bags but not hemolysis Islamzada E, Matthews K, Lamoureux E, Duffy SP, Scott MD, Ma H 2022 Transfusion View Researchers Basic research
Donor-recipient sex is associated with transfusion-related outcomes in critically ill patients Alshalani A, Uhel F, Cremer OL, Schultz MJ, de Vooght KMK, van Bruggen R, Acker JP, Juffermans NP, on behalf of the MARS Consortium 2022 Blood Adv View Researchers Clinical research
Blood Donation Testing and the Safety of the Blood Supply Goldman M, Drews SJ 2022 Practical Transfusion Medicine View Health care providers Benchmarking and standard setting
FAQ: Canadian Blood Services platelet bacterial screening Khandelwal A, Ramirez-Arcos S, Bigham M 2022 Blood.ca website View Health care providers Benchmarking and standard setting
FAQ : Le sang total déleucocyté à la Société canadienne du sang Mack J 2022 Blood.ca website View Health care providers New or improved product or process
A Portrait of Cord Blood Units Distributed for Transplantation from Canadian Blood Services’ Cord Blood Bank: First Analysis Parmar G, Green M, Mostert K, Lawless T, Dibdin N, Weiss J, Ganz K, Petraszko T, Seftel MD, Allan DS 2022 Curr Oncol View Researchers Benchmarking and standard setting
Circulaire d'information utilisation de composants sanguins humains: Sang total Stewart T 2022 Blood.ca website View Health care providers Benchmarking and standard setting
Babesia microti in a Canadian blood donor and lookback in a red blood cell recipient Drews SJ, Van Caeseele P, Bullard J, Lindsay LR, Gaziano T, Zeller MP, Lane D, Ndao M, Allen VG, Boggild AK, O'Brien SF, Marko D, Musuka C, Almiski M, Bigham M 2022 Vox Sang View Health care providers Clinical research
Hemolysis after high-dose intravenous immunoglobulin: An under-appreciated sequelae Branch DR, Almizraq RJ, Bussel JB 2022 Am J Hematol View Researchers Basic research
Prolonged Blood Storage and Risk of Posttransfusion Acute Kidney Injury Adegboye J, Sapatnekar S, Mascha EJ, Shah K, Lioudis M, Essber H, Cohen B, Rivas E, Heddle NM, Eikelboom JW, Ellis MH, Sharon Y, Sinha R, Kurz A, Sessler DI 2022 Anesthesiology View Researchers Clinical research
Chapter 19. Pathogen-reduced platelets Blais-Normandin I, Tordon B, Anani W, Ning S 2022 Clinical Guide to Transfusion View Health care providers Benchmarking and standard setting
THP-1 cells transduced with CD16A utilize Fcγ receptor I and III in the phagocytosis of IgG-sensitized human erythrocytes and platelets Gil Gonzalez L, Fernandez-Marrero Y, Norris PAA, Tawhidi Z, Shan Y, Cruz-Leal Y, Won KD, Frias-Boligan K, Branch DR, Lazarus AH 2022 PLoS One View Researchers Basic research
ABO O blood group as a risk factor for platelet reactivity in heparin-induced thrombocytopenia Karnes JH, Rollin J, Giles JB, Martinez KL, Steiner HE, Shaffer CM, Momozawa Y, Inai C, Bombin A, Shi M, Mosley JD, Stanaway I, Selleng K, Thiele T, Mushiroda T, Pouplard C, Heddle NM, Kubo M, Phillips EJ, Warkentin TE, Gruel Y, Greinacher A, Roden DM 2022 Blood View Researchers Basic research
Ex vivo enzymatic treatment converts blood type A donor lungs into universal blood type lungs Wang A, Ribeiro RVP, Ali A, Brambate E, Abdelnour-Berchtold E, Michaelsen V, Zhang Y, Rahfeld P, Moon H, Gokhale H, Gazzalle A, Pal P, Liu M, Waddell TK, Cserti-Gazdewich C, Tinckam K, Kizhakkedathu JN, West L, Keshavjee S, Withers SG, Cypel M 2022 Sci Transl Med View Researchers Clinical research
Preparing small-dose red cell concentrates (RCCs) for neonatal and pediatric transfusions: Impact of RCC volume, storage, and irradiation Olafson C, William N, Howell A, Beaudin L, Gill B, Clarke G, Stephens S, Lopes-Carvalho D, Lane D, Schubert P, McTaggart K, Acker JP 2022 Transfusion View Researchers New or improved product or process
Circular of information for the use of human blood components: Hematopoietic Progenitor Cells (HPC), Cord Blood Stewart T 2022 Blood.ca website View Health care providers Benchmarking and standard setting
Epidemiology, diagnosis and management of neonatal thrombosis: a single-center cohort study Paes B, Chan AKC, Shaik M, Patel D, Bhatt MD 2022 Blood Coagul Fibrinolysis View Health care providers Clinical research
Sexual risk behavior questions: Understanding and mitigating donor discomfort Haw J, Woo H, Kohut T, Fisher W 2022 Transfusion View Blood operators MSM research
Mixing study to diagnose heparin-resistance caused by functional antithrombin deficiency Bahabri A, Moffat KA, Carlino SA, Chan AKC, Bhatt MD 2022 Int J Lab Hematol View Researchers Basic research
Filamin A regulates caspase-3 cleavage in platelets in a protein kinase C (PKC)-dependent manner De Silva E, Devine DV, Jan E, Roskelley CD, Kim H 2022 Biochem J View Researchers Basic research
Model of Acute Liver Failure in an Isolated Perfused Porcine Liver—Challenges and Lessons Learned Hefler J, Hatami S, Thiesen A, Olafson C, Durand K, Acker J, Karvellas CJ, Bigam DL, Freed DH, Shapiro AMJ 2022 Biomedicines View Researchers New or improved product or process
Chapitre 10. Les réactions transfusionnelles Laureano M, Khandelwal A, Yan M 2022 Guide de la pratique transfusionnelle View Health care providers Benchmarking and standard setting
Coagulation and complement: Key innate defense participants in a seamless web Pryzdial ELG, Leatherdale A, Conway EM 2022 Front Immunol View Researchers Basic research
ResearchUnit: Evaluating infusion pump safety for red blood cell transfusions Wolfe A 2022 Blood.ca website View Researchers Benchmarking and standard setting
The Missing Pieces to the Cold-Stored Platelet Puzzle Zhao H, Devine DV 2022 Int J Mol Sci View Researchers Basic research
Use of CRISPR/Cas9 gene editing to improve chimeric antigen-receptor T cell therapy: A systematic review and meta-analysis of preclinical studies Maganti HB, Kirkham AM, Bailey AJM, Shorr R, Kekre N, Pineault N, Allan DS 2022 Cytotherapy View Researchers Clinical research
The international experience of bacterial screen testing of platelet components with automated microbial detection systems: An update Kamel H, Ramirez-Arcos S, McDonald C, ISBT Transfusion-Transmitted Infectious Disease Bacterial Working Party Bacterial Subgroup 2022 Vox Sang View Researchers Benchmarking and standard setting
Vaccine-induced immune thrombotic thrombocytopenia (VITT): Update on diagnosis and management considering different resources Greinacher A, Langer F, Makris M, Pai M, Pavord S, Tran H, Warkentin TE 2022 J Thromb Haemost View Health care providers Clinical research
Cytomegalovirus Seropositivity in Older Adults Changes the T Cell Repertoire but Does Not Prevent Antibody or Cellular Responses to SARS-CoV-2 Vaccination Breznik JA, Huynh A, Zhang A, Bilaver L, Bhakta H, Stacey HD, Ang JC, Bramson JL, Nazy I, Miller MS, Denburg J, Costa AP, Bowdish DME 2022 J Immunol View Health care providers Clinical research
HIV incidence and related risks among gay, bisexual, and other men who have sex with men in Montreal, Toronto, and Vancouver: Informing blood donor selection criteria in Canada Lambert G, Cox J, Fourmigue A, Dvorakova M, Apelian H, Moodie EEM, Grace D, Skakoon-Sparling S, Moore DM, Lachowsky N, Jollimore J, Lal A, Parlette A, Hart TA 2022 Transfusion View Researchers MSM research
Chapter 5. Concentrates for hemostatic disorders and hereditary angioedema Poon MC, Goodyear D, Rydz N, Lee A 2022 Clinical Guide to Transfusion View Health care providers Benchmarking and standard setting
Retention of hemostatic and immunological properties of frozen plasma and COVID-19 convalescent apheresis fresh-frozen plasma produced and freeze-dried in Canada Sheffield WP, Bhakta V, Howell A, Jenkins C, Serrano K, Johnson N, Lin Y-CJ, Colwill K, Rathod B, Greenberg B, Gingras A-C, Evans DH, Flaumenhaft E, Beckett A, Drews SJ, Devine DV 2022 Transfusion View Researchers Basic research
Multicenter evaluation of the IL-3-pSTAT5 assay to assess the potency of cryopreserved stem cells from cord blood units: The BEST Collaborative study Trépanier P, Fournier D, Simard C, Fontaine MJ, Stroncek D, Takanashi M, McKenna D, Schwartz J, Tanhehco YC, Reems J-A, Torrents S, Kogler G, Liedtke S, Giroux M, Holovati JL, Louis I, Prasath A, Pineault N, Bazin R, The Biomedical Excellence for Safer Transfusion Collaborative 2022 Transfusion View Researchers Benchmarking and standard setting
Comparison of Neutrophil Function in Granulocyte Concentrates From Prednisone- and G-CSF-Treated Donors: Effect of Stimulant, Leukapheresis and Storage Murru A, Allard M-È, Paré G, Vaillancourt M, Boyer L, Cayer M-P, Vitry J, Landry P, Labrecque M-M, Robitaille N, Branch DR, Girard M, Fernandes MJ 2022 Front Med View Researchers Basic research
Comparative 6-Month Wild-Type and Delta-Variant Antibody Levels and Surrogate Neutralization for Adults Vaccinated with BNT162b2 versus mRNA-1273 Grunau B, Golding L, Prusinkiewicz MA, Asamoah-Boaheng M, Armour R, Marquez AC, Jassem AN, Barakauskas V, O’Brien SF, Drews SJ, Haig S, Lavoie PM, Goldfarb DM 2022 Microbiol Spectr View Researchers Clinical research
The impact of donor ferritin testing on blood availability in Canada Blake JT, O'Brien SF, Goldman M 2022 Vox Sang View Blood operators New or improved product or process