Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Platelets in hemostasis and thrombosis: Novel mechanisms of fibrinogen-independent platelet aggregation and fibronectin-mediated protein wave of hemostasis Hou Y, Carrim N, Wang Y, Gallant RC, Marshall A, Ni H 2015 J Biomed Res View Researchers Basic research
Progressive development of polycystic kidney disease in the mouse model expressing Pkd1 extracellular domain Kurbegovic A, Trudel M 2013 Hum Mol Genet View Researchers Basic research
Red blood cell processing methods and in-hospital mortality: a transfusion registry cohort study Heddle NM, Arnold DM, Acker JP, Liu Y, Barty RL, Eikelboom JW, Webert KE, Hsia CC, O'Brien SF, Cook RJ 2016 Lancet Haematol View Researchers Clinical research
Subunit-directed click coupling via doubly cross-linked hemoglobin efficiently produces readily purified functional bis-tetrameric oxygen carriers Singh S, Dubinsky-Davidchik IS, Yang Y, Kluger R 2015 Org Biomol Chem View Researchers Basic research
The neonatal Fc receptor (FcRn) is not required for IVIg or anti-CD44 monoclonal antibody–mediated amelioration of murine immune thrombocytopenia Crow AR, Suppa SJ, Chen X, Mott PJ, Lazarus AH 2011 Blood View Researchers Basic research
Thrombocytopenia in the critically ill Shehata N, Fontes ML 2013 Can J Anaesth View Researchers Other
Transfusion-transmitted malaria: is hope around the corner? O'Brien SF 2016 Lancet View Researchers Other
Vitamin D and kidney transplant outcomes: a protocol for a systematic review and meta-analysis Hesketh CC, Knoll GA, Molnar AO, Tsampalieros A, Zimmerman DL 2014 Syst Rev View Researchers Clinical research
ResearchUnit: Patient blood group impacts susceptibility to IVIg-associated hemolysis Branch D 2018 Blood.ca website View Researchers Basic research
A Deep Learning Method to Automatically Identify Reports of Scientifically Rigorous Clinical Research from the Biomedical Literature: Comparative Analytic Study Del Fiol G MM, Iorio A, Cotoi C, Haynes RB 2018 J Med Internet Res View Researchers Clinical research
The peptidoglycan and biofilm matrix of Staphylococcus epidermidis undergo structural changes when exposed to human platelets Loza-Correa M, Ayala JA, Perelman I, Hubbard K, Kalab M, Yi Q-L, Taha M, de Pedro MA, Ramirez-Arcos S 2019 PLoS One View Researchers Basic research
Systematic reviews of guidelines and studies for single versus multiple unit transfusion strategies Shih AW, Liu A, Elsharawi R, Crowther MA, Cook RJ, Heddle NM 2018 Transfusion View Researchers Clinical research
Evaluating the quality of red blood cell concentrates irradiated before or after cryopreservation Turner TR, Lautner L, Hill A, Howell A, Skeate R, Acker JP 2020 Transfusion View Researchers Basic research
Antithrombotics from Frog Skin Secretions Ni H 2020 Thromb Haemost View Researchers Basic research
FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex-driven autoimmunity Hubbard JJ, Pyzik M, Rath T, Kozicky LK, Sand KMK, Gandhi AK, Grevys A, Foss S, Menzies SC, Glickman JN, Fiebiger E, Roopenian DC, Sandlie I, Andersen JT, Sly LM, Baker K, Blumberg RS 2020 J Exp Med View Researchers Basic research
Mouse Models of Rheumatoid Arthritis for Studies on Immunopathogenesis and Preclinical Testing of Fc Receptor-Targeting Biologics Lewis BJB, Branch DR 2020 Pharmacology View Researchers Basic research
Quality of evidence-based guidelines for platelet transfusion and use: A systematic review Al-Riyami AZ, Jug R, La Rocca U, Keshavarz H, Landry D, Shehata N, Stanworth SJ, Nahirniak S 2021 Transfusion View Researchers Benchmarking and standard setting
Themed issue – focusing on donor assessment, motivation and vigilance O’Brien SF, Ullum H, Seed CR 2021 Vox Sang View Researchers New or improved product or process
Factor product utilization and health outcomes in patients with haemophilia A and B on extended half-life concentrates: A Canadian observational study of real-world outcomes Sun H, Yang M, Poon M-C, Lee A, Robinson KS, Sholzberg M, Wu J, Iorio A, Blanchette V, Carcao M, Klaassen RJ, Jackson S 2021 Haemophilia View Researchers Clinical research
Challenging the 30-min rule for thawed plasma Ramirez-Arcos S, Howell A, Bearne J, Bhakta V, Bower L, Cardigan R, Girard M, Kou Y, McDonald C, Nolin M-È, Sawicka D, Sheffield W 2021 Vox Sang View Researchers Benchmarking and standard setting
How do I think about blood donor eligibility criteria for medical conditions? Goldman M 2021 Transfusion View Researchers Benchmarking and standard setting
A scalable serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccination Colwill K, Galipeau Y, Stuible M, Gervais C, Arnold C, Rathod B, Abe KT, Wang JH, Pasculescu A, Maltseva M, Rocheleau L, Pelchat M, Fazel-Zarandi M, Iskilova M, Barrios-Rodiles M, Bennett L, Yau K, Cholette F, Mesa C, Li AX, Paterson A, Hladunewich MA, Goodwin PJ, Wrana JL, Drews SJ, Mubareka S, McGeer AJ, Kim J, Langlois M-A, Gingras A-C, Durocher Y 2022 medRxiv View Researchers New or improved product or process
ResearchUnit: A proposed mechanism for vaccine-induced thrombotic thrombocytopenia Batarfi K 2021 Blood.ca website View Researchers Clinical research
The Effect of Sex-Mismatched Red Blood Cell Transfusion on Endothelial Cell Activation in Critically Ill Patients Alshalani A, van Manen L, Boshuizen M, van Bruggen R, Acker JP, Juffermans NP 2022 Transfus Med Hemother View Researchers Clinical research
A thermoreversible poly(choline phosphate) based universal biomembrane adhesive Yu X, Yang X, Horte S, Kizhakkedathu JN, Brooks DE 2014 Macromol Biosci View Researchers Basic research
Antigen modulation as a potential mechanism of anti-KEL immunoprophylaxis in mice Liu J, Santhanakrishnan M, Natarajan P, Gibb DR, Eisenbarth SC, Tormey CA, Siddon AJ, Stowell SR, Branch DR, Hendrickson JE 2016 Blood View Researchers Basic research
Bacterial survival and distribution during buffy coat platelet production Taha M, Kalab M, Yi QL, Maurer E, Jenkins C, Schubert P, Ramirez-Arcos S 2016 Vox Sang View Researchers New or improved product or process
Chloride and other electrolyte concentrations in commonly available 5% albumin products Lai AT, Zeller MP, Millen T, Kavsak P, Szczeklik W, Elahie A, Alhazzani W, D'Aragon F, Jaeschke R, Lamontagne F, Karachi T, Cook D, Meade M, Rochwerg B 2018 Crit Care Med View Researchers Clinical research
Concentré de recherche: La présence de résidus de plasma favorise l'adhérence des bactéries à la paroi des poches utilisées pour les concentrés de plaquettes Ramirez-Arcos S 2017 Blood.ca website View Researchers Basic research
Design of long circulating nontoxic dendritic polymers for the removal of iron in vivo Imran ul-haq M, Hamilton JL, Lai BF, Shenoi RA, Horte S, Constantinescu I, Leitch HA, Kizhakkedathu JN 2013 ACS Nano View Researchers Basic research
Does intravenous contrast-enhanced computed tomography cause acute kidney injury? Protocol of a systematic review of the evidence Kayibanda JF, Hiremath S, Knoll GA, Fergusson D, Chow BJ, Shabana W, Akbari A 2014 Syst Rev View Researchers Clinical research
Efficacy of HLA-matched platelet transfusions for patients with hypoproliferative thrombocytopenia: a systematic review Pavenski K, Rebulla P, Duquesnoy R, Saw CL, Slichter SJ, Tanael S, Shehata N, International Collaboration for Guideline Development Implementation and Evaluation for Transfusion Therapies (ICTMG) Collaborators 2013 Transfusion View Researchers Clinical research
In silico analysis suggests interaction between Ebola virus and the extracellular matrix Veljkovic V, Glisic S, Muller CP, Scotch M, Branch DR, Perovic VR, Sencanski M, Veljkovic N, Colombatti A 2015 Front Microbiol View Researchers Basic research
Low-intensity pulsed ultrasound-mediated stimulation of hematopoietic stem/progenitor cell viability, proliferation and differentiation in vitro Xu P, Gul-Uludag H, Ang WT, Yang X, Huang M, Marquez-Curtis L, McGann L, Janowska-Wieczorek A, Xing J, Swanson E, Chen J 2012 Biotechnol Lett View Researchers Basic research
Microscope-based label-free microfluidic cytometry Su X, Kirkwood SE, Gupta M, Marquez-Curtis L, Qiu Y, Janowska-Wieczorek A, Rozmus W, Tsui YY 2011 Opt Express View Researchers New or improved product or process
N-ethylmaleimide activates a Cl(-)-independent component of K(+) flux in mouse erythrocytes Shmukler BE, Hsu A, Alves J, Trudel M, Rust MB, Hubner CA, Rivera A, Alper SL 2013 Blood Cells Mol Dis View Researchers Basic research
Quality and Safety of Blood Products Ramirez-Arcos S, Marks DC, Acker JP, Sheffield WP 2016 J Blood Transfus View Researchers Other
Riboflavin and ultraviolet light treatment potentiates vasodilator-stimulated phosphoprotein Ser-239 phosphorylation in platelet concentrates during storage Schubert P, Culibrk B, Coupland D, Scammell K, Gyongyossy-Issa M, Devine DV 2012 Transfusion View Researchers Basic research
The efficacy and safety of topical tranexamic acid: A systematic review and meta-analysis Montroy J, Hutton B, Moodley P, Fergusson NA, Cheng W, Tinmouth A, Lavallee LT, Fergusson DA, Breau RH 2018 Transfus Med Rev View Researchers Clinical research
The promise of organ and tissue preservation to transform medicine Giwa S, Lewis JK, Alvarez L, Langer R, Roth AE, Church GM, Markmann JF, Sachs DH, Chandraker A, Wertheim JA, Rothblatt M, Boyden E, Eidbo E, Lee A, Pomahac B, Brandacher, Weinstock D, Elliott G, Nelson D, Acker JP, Uygun K, Schmalz B, Weegman B, Tocchio A, Fahy GM 2017 Nat Biotechnol View Researchers New or improved product or process
Toward Efficient Enzymes for the Generation of Universal Blood through Structure-Guided Directed Evolution Kwan DH, Constantinescu I, Chapanian R, Higgins MA, Kotzler MP, Samain E, Boraston AB, Kizhakkedathu JN, Withers SG 2015 J Am Chem Soc View Researchers New or improved product or process
Unraveling the IVIG mystique Branch DR 2013 Transfusion View Researchers Other
Psychometric properties of the Patient Reported Outcomes, Burdens and Experiences (PROBE) questionnaire Chai-Adisaksopha C, Skinner MW, Curtis R, Frick N, Nichol MB, Noone D, O'Mahony B, Page D, Stonebraker J, Thabane L, Crowther M, Iorio A 2018 BMJ Open View Researchers Clinical research
Antiplatelet antibody-induced thrombocytopenia does not correlate with megakaryocyte abnormalities in murine immune thrombocytopenia Guo L, Kapur R, Aslam R, Hunt K, Hou Y, Zufferey A, Speck ER, Rondina MT, Lazarus AH, Ni H, Semple JW 2018 Scand J Immunol View Researchers Basic research
Biocompatibility and toxicity of novel iron chelator Starch-Deferoxamine (S-DFO) compared to zinc oxide nanoparticles to zebrafish embryo: An oxidative stress based apoptosis, physicochemical and neurological study profile Nasrallah GK, Salem R, Da'as S, Al-Jamal OLA, Scott M, Mustafa I 2019 Neurotoxicol Teratol View Researchers Basic research
Modelling the Need for New Blood Donors Following a Change in Deferral Period Blake J 2019 Industrial Engineering and Operations Management View Researchers New or improved product or process
The use of IVIg in fetal and neonatal alloimmune thrombocytopenia— Principles and mechanisms Wabnitz H, Khan R, Lazarus AH 2020 Transfus Apher Sci View Researchers Clinical research
Blood donation and the global COVID-19 pandemic: areas for social science research Haw J, Holloway K, Masser B, Merz E-M, Thrope R 2020 Vox Sang View Researchers New or improved product or process
Transitioning to Full Field Digital Mammography in Nova Scotia: Using Interrupted Time Series Methods to Study the Impact of Technology Change on Mammography Volumes Brydon M, Kephart G, Payne JI, Blake J 2020 J Med Imaging Radiat Sci View Researchers New or improved product or process
Fostamatinib for the treatment of warm antibody autoimmune hemolytic anemia: Phase 2, multicenter, open-label study Kuter DJ, Rogers KA, Boxer MA, Choi M, Agajanian R, Arnold DM, Broome CM, Field JJ, Murakhovskaya I, Numerof R, Tong S 2022 Am J Hematol View Researchers Clinical research