Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
SARS-CoV-2 seroprevalence among blood donors after the first COVID-19 wave in Canada Saeed S, Drews SJ, Pambrun C, Yi Q-L, Osmond L, O'Brien SF 2021 Transfusion View Researchers Clinical research
Updated Understanding of Platelets in Thrombosis and Hemostasis: The Roles of Integrin PSI Domains and their Potential as Therapeutic Targets MacKeigan DT, Ni T, Shen C, Stratton TW, Ma W, Zhu G, Bhoria P, Ni H 2020 Cardiovasc Hematol Disord Drug Targets View Researchers Basic research
SARS-CoV-2 Virus-Like Particle Neutralizing Capacity in Blood Donors Depends on Serological Profile and Donor-Declared SARS-CoV-2 Vaccination History Drews SJ, Hu Q, Samson R, Abe KT, Rathod B, Colwill K, Gingras A-C, Yi Q-L, O’Brien SF, Mostafa HH 2022 Microbiol Spectr View Researchers Clinical research
National Blood Foundation 2021 Research and Development summit: Discovery, innovation, and challenges in advancing blood and biotherapies Holmberg JA, Henry SM, Burnouf T, Devine D, Marschner S, Boothby TC, Burger SR, Chou ST, Custer B, Blumberg N, Siegel DL, Spitalnik SL 2022 Transfusion View Researchers Benchmarking and standard setting
Development and internal validation of a clinical prediction model for the diagnosis of immune thrombocytopenia Li N, Mahamad S, Parpia S, Iorio A, Foroutan F, Heddle NM, Hsia CC, Sholzberg M, Rimmer E, Shivakumar S, Sun HL, Refaei M, Hamm C, Arnold DM 2022 J Thromb Haemost View Researchers New or improved product or process
Immunospecific analysis of in vitro and ex vivo surface-immobilized protein complex Sask KN, Thong B, Goodarzynejad N, Berry LR, Chan AKC 2022 Biointerphases View Researchers Basic research
GRADE Guidance 34: update on rating imprecision using a minimally contextualized approach Zeng L, Brignardello-Petersen R, Hultcrantz M, Mustafa RA, Murad MH, Iorio A, Traversy G, Akl EA, Mayer M, Schünemann HJ, Guyatt GH 2022 J Clin Epidemiol View Researchers Clinical research
A synthetic globotriaosylceramide analogue inhibits HIV-1 infection in vitro by two mechanisms Harrison AL, Olsson ML, Jones RB, Ramkumar S, Sakac D, Binnington B, Henry S, Lingwood CA, Branch DR 2010 Glycoconj J View Researchers Basic research
Alleviation of gram-negative bacterial lung inflammation by targeting HECTD2 Kapur R, Semple JW 2016 Ann Transl Med View Researchers Basic research
Antibody specific for the glycophorin A complex mediates intravenous immune globulin-resistant anemia in a murine model Chen X, Ghaffar H, Jen CC, Lazarus AH 2014 Transfusion View Researchers Basic research
Blood Group Antigen Matching Influence on Gestational Outcomes (AMIGO) study Delaney M, Wikman A, van de Watering L, Schonewille H, Verdoes JP, Emery SP, Murphy MF, Staves J, Flach S, Arnold DM, Kaufman RM, Ziman A, Harm SK, Fung M, Eppes CS, Dunbar NM, Buser A, Meyer E, Savoia H, Abeysinghe P, Heddle N, Tinmouth A, Traore AN, Yazer MH, for the Best Collaborative 2017 Transfusion View Researchers Clinical research
Characterization of SHP-1 protein tyrosine phosphatase transcripts, protein isoforms and phosphatase activity in epithelial cancer cells Evren S, Wan S, Ma XZ, Fahim S, Mody N, Sakac D, Jin T, Branch DR 2013 Genomics View Researchers Basic research
Dengue virus persists and replicates during storage of platelet and red blood cell units Sutherland MR, Simon AY, Serrano K, Schubert P, Acker JP, Pryzdial ELG 2016 Transfusion View Researchers Basic research
Disulfide linked pyrazole derivatives inhibit phagocytosis of opsonized blood cells Purohit MK, Scovell I, Neschadim A, Katsman Y, Branch DR, Kotra LP 2013 Bioorg Med Chem Lett View Researchers Basic research
Effects of methoxypoly (Ethylene glycol) mediated immunocamouflage on leukocyte surface marker detection, cell conjugation, activation and alloproliferation Kyluik-Price DL, Scott MD 2016 Biomaterials View Researchers Basic research
Growth factor independence 1b (gfi1b) is important for the maturation of erythroid cells and the regulation of embryonic globin expression Vassen L, Beauchemin H, Lemsaddek W, Krongold J, Trudel M, Moroy T 2014 PLoS One View Researchers Basic research
Ice recrystallization inhibitors: from biological antifreezes to small molecules Capicciotti CJ, Doshi M, Ben RN 2013 Recent developments in the study of recrystallization View Researchers Basic research
Improved mouse models for the study of treatment modalities for immune-mediated platelet destruction Katsman Y, Foo AH, Leontyev D, Branch DR 2010 Transfusion View Researchers Basic research
Low levels of interleukin-10 in patients with transfusion-related acute lung injury Kapur R, Kim M, Rebetz J, Rondina MT, Porcelijn L, Semple JW 2017 Ann Transl Med View Researchers Clinical research
Microfluidic deformability analysis of the red cell storage lesion Matthews K, Myrand-Lapierre M-E, Ang RR, Duffy SP, Scott MD, Ma H 2015 J Biomech View Researchers New or improved product or process
Myasthenia gravis treated with autologous hematopoietic stem cell transplantation Bryant A, Atkins H, Pringle C, Allan D, Anstee G, Bence-Bruckler I, Hamelin L, Hodgins M, Hopkins HS, Huebsch L, McDiarmid S, Sabloff M, Sheppard D, Tay J, Bredeson C 2016 JAMA Neurol View Researchers Clinical research
Plasma and cryoprecipitate for transfusion Stanworth SJ, Tinmouth AT 2016 Rossi's Principles of Transfusion Medicine View Researchers Basic research
Polymeric Nanoparticle-Mediated Silencing of CD44 Receptor in CD34+ Acute Myeloid Leukemia Cells Gul-Uluda H, Valencia-Serna J, Kucharski C, Marquez-Curtis LA, Jiang X, Larratt L, Janowska-Wieczorek A, Uluda H 2014 Leukemia Res View Researchers Basic research
RhD Specific Antibodies Are Not Detectable in HLA-DRB1(*)1501 Mice Challenged with Human RhD Positive Erythrocytes Bernardo L, Denomme GA, Shah K, Lazarus AH 2014 Adv Hematol View Researchers Basic research
Severe platelet desialylation in a patient with glycoprotein Ib/IX antibody-mediated immune thrombocytopenia and fatal pulmonary hemorrhage Li J, Callum JL, Lin Y, Zhou Y, Zhu G, Ni H 2014 Haematologica View Researchers Clinical research
Thymic-derived tolerizing dendritic cells are upregulated in the spleen upon treatment with intravenous immunoglobulin in a murine model of immune thrombocytopenia Kapur R, Aslam R, Kim M, Guo L, Ni H, Segel GB, Semple JW 2016 Platelets View Researchers Basic research
45 - Alloimmune Thrombocytopenia Kaplan C, Bertrand G, Ni H 2019 Platelets (Fourth Edition) View Researchers New or improved product or process
Red blood cell antibody-induced anemia causes differential degrees of tissue hypoxia in kidney and brain Mistry N, Mazer CD, Sled JG, Lazarus AH, Cahill LS, Solish M, Zhou Y-Q, Romanova N, Hare AGM, Doctor A, Fisher JA, Brunt KR, Simpson JA, Hare GMT 2018 Am J Physiol Regul Integr Comp Physiol View Researchers Basic research
Evaluation of a hydrogel-based diagnostic approach for the point-of-care based detection of Neisseria gonorrhoeae Perera S, Taheri A, Khan N, Parti R, Stefura S, Skiba P, Acker J, Martin I, Kusalik A, Dillon J-A 2018 Antibiotics View Researchers New or improved product or process
Translating red cell "omics" into new perspectives in transfusion medicine: mining the gems in the data mountains Spitalnik SL, Devine DV 2019 Transfusion View Researchers Other
Enhancing the pro-inflammatory anti-cancer T cell response via biomanufactured, secretome-based, immunotherapeutics Yang X, Kang N, Toyofuku WM, Scott MD 2018 Immunobiology View Researchers Basic research
Concentré de recherche: Améliorer les analyses de qualité réalisées sur les cellules souches destinées à la greffe Pineault N 2020 Blood.ca website View Researchers New or improved product or process
Gay and bisexual men’s views on reforming blood donation policy in Canada: a qualitative study Grace D, Gaspar M, Lessard D, Klassen B, Brennan DJ, Adam BD, Jollimore J, Lachowsky NJ, Hart TA 2019 BMC Public Health View Researchers Other
Transfusion of Uncrossmatched Group O Erythrocyte-containing Products Does Not Interfere with Most ABO Typings Yazer MH, Spinella PC, Doyle L, Kaufman RM, Dunn R, Hess JR, Filho LA, Fontaine M, Gathof B, Jackson B, Murphy MF, Pasion J, Raval JS, Rosinski K, Seheult J, Shih AW, Sperry J, Staves J, Tuott EE, Ziman A, Triulzi DJ, Biomedical Excellence for Safer Transfusion Collaborative 2020 Anesthesiology View Researchers Clinical research
Biological Modulation of the Treg:Teff Ratio: From Immunosuppression to Immunoactivation Yang X, Scott M 2020 Immunosupression View Researchers Basic research
Differential red blood cell age fractionation and Band?3 phosphorylation distinguish two different subtypes of warm autoimmune hemolytic anemia Bloch EM, Branch HA, Sakac D, Leger RM, Branch DR 2020 Transfusion View Researchers Basic research
Management of heparin-induced thrombocytopenia: systematic reviews and meta-analyses Morgan RL, Ashoorion V, Cuker A, Begum H, Ross S, Martinez N, Chong BH, Linkins LA, Warkentin TE, Wiercioch W, Nieuwlaat R, Schünemann H, Santesso N 2020 Blood Adv View Researchers Clinical research
Tantalum-containing meso-porous glass fibres for hemostatic applications Nagrath M, Rahimnejad Yazdi A, Rafferty A, Daly D, Rahman SU, Gallant RC, Ni H, Arany PR, Towler MR 2021 Mater Today Commun View Researchers Basic research
Genome Sequence of Staphylococcus aureus Strain CBS2016-05, Isolated from Contaminated Platelet Concentrates in Canada Yousuf B, Flint A, Weedmark K, Pagotto F, Ramirez-Arcos S, Hotopp JCD 2021 Microbiol Resour Announc View Researchers Benchmarking and standard setting
Survey of blood centre readiness regarding removal of DEHP from blood bag sets: The BEST Collaborative Study Razatos A, Acker JP, de Korte D, Bégué S, Noorman F, Doyle B, Zia M, Min K, The Biomedical Excellence for Safer Transfusion Collaborative 2022 Vox Sang View Researchers New or improved product or process
Peptide-Modified Surfaces for Binding Carbamylated Proteins from Plasma Ma Y, Hadjesfandiari N, Doschak M, Devine D, Tonelli M, Unsworth L 2021 Langmuir View Researchers Basic research
A systematic review of the association between anti-?-2 glycoprotein I antibodies and APS manifestations Jiang D, Lim W, Crowther M, Garcia D 2021 Blood Adv View Researchers Clinical research
International survey of strategies to mitigate transfusion-transmitted Trypanosoma cruzi in non-endemic countries, 2016–2018 Crowder LA, Wendel S, Bloch EM, O'Brien SF, Delage G, Sauleda S, Leiby DA, for the WP-TTID Subgroup on Parasites 2022 Vox Sang View Researchers Benchmarking and standard setting
Convalescent plasma for adults with acute COVID-19 respiratory illness (CONCOR-1): study protocol for an international, multicentre, randomized, open-label trial Bégin P, Callum J, Heddle NM, Cook R, Zeller MP, Tinmouth A, Fergusson DA, Cushing MM, Glesby MJ, Chassé M, Devine DV, Robitalle N, Bazin R, Shehata N, Finzi A, McGeer A, Scales DC, Schwartz L, Turgeon AF, Zarychanski R, Daneman N, Carl R, Amorim L, Gabe C, Ellis M, Sachais BS, Loftsgard KC, Jamula E, Carruthers J, Duncan J, Lucier K, Li N, Liu Y, Armali C, Kron A, Modi D, Auclair M-C, Cerro S, Avram M, Arnold DM 2021 Trials View Researchers Clinical research
(NZW × BXSB) F1 male mice: An unusual, severe and fatal mouse model of lupus erythematosus Almizraq RJ, Frias Boligan K, Loriamini M, McKerlie C, Branch DR 2022 Front Immunol View Researchers Basic research
Genome-wide association study of platelet factor 4/heparin antibodies in heparin-induced thrombocytopenia Giles JB, Steiner HE, Rollin J, Shaffer CM, Momozawa Y, Mushiroda T, Inai C, Selleng K, Thiele T, Pouplard C, Heddle NM, Kubo M, Miller EC, Martinez KL, Phillips EJ, Warkentin TE, Gruel Y, Greinacher A, Roden DM, Karnes JH 2022 Blood Adv View Researchers Basic research
Acid sphingomyelinase mediates murine acute lung injury following transfusion of aged platelets McVey MJ, Kim M, Tabuchi A, Srbely V, Japtok L, Arenz C, Rotstein O, Kleuser B, Semple JW, Kuebler WM 2017 Am J Physiol Lung Cell Mol Physiol View Researchers Basic research
Alzheimer Disease in a Mouse Model: MR Imaging–guided Focused Ultrasound Targeted to the Hippocampus Opens the Blood-Brain Barrier and Improves Pathologic Abnormalities and Behavior Burgess A, Dubey S, Yeung S, Hough O, Eterman N, Aubert I, Hynynen K 2014 Radiology View Researchers Basic research
Bioorthogonal phase-directed copper-catalyzed azide–alkyne cycloaddition (PDCuAAC) coupling of selectively cross-linked superoxide dismutase dimers produces a fully active bis-dimer Siren EM, Singh S, Kluger R 2015 Org Biomol Chem View Researchers Basic research
Cardiorespiratory pathogenesis of sickle cell disease in a mouse model Ren J, Ding X, Trudel M, Greer JJ, MacLean JE 2017 Sci Rep View Researchers Basic research