Our Funded Research Projects

Updated April 2024

Title Principal Investigator / Supervisor Program Project Start Date Project End Date Sort ascending Total $ Awarded
The mechanism of action of monoclonal antibody blends in the potential replacement of anti-D in HDFN Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: CRUZ-LEAL, Yoelys
Postdoctoral Fellowship Program 165000.0
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: SHIH, Andrew

Co-Investigator(s) / Trainee: TAPLEY, Laura
Elianna Saidenberg Transfusion Medicine Traineeship Award 105000.0
Novel cell-surface engineering methods to increase immune-tolerance of allogenic cell transplantation Principal Investigator: KIZHAKKEDATHU, Jayachandran

Co-Investigator(s) / Trainee: MOON, Haisle
Graduate Fellowship Program 90333.3
Expanding treatment options for inflammatory bowel disease: A novel mechanism of antibody-based immunotherapy Principal Investigator: SLY, Laura

Co-Investigator(s) / Trainee: HORWITZ, Marc, BRESSLER, Brian, RASSEKH, Rod, TURVEY, Stuart
Canadian Blood Services-CIHR Partnership Operating Grant Program 408540.6
Fetal and neonatal alloimmune thrombocytopenia: novel mechanisms and therapeutic approaches Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership Operating Grant Program 471393.0
Canadians’ attitudes and opinions regarding cardiac donation after cardiocirculatory death: A mixed-methods study Principal Investigator: BALL, Ian

Co-Investigator(s) / Trainee: WEISS, Matt, D'ARAGON, Fred, PARSONS LEIGH, Jenna, HONARMAND, Kimia, BASMAJI, John, SIBBALD, Robert
Kenneth J. Fyke Award Program 95929.0
Novel mechanisms of platelet aggregation: Roles of non-classical beta-3 integrin ligands and fibronectin in thrombosis and hemostasis Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership Operating Grant Program 398871.0
Virtual transfusions competency assessment Principal Investigator: VAN VLIET, Paula

Co-Investigator(s) / Trainee: DEYDEY, Kim, WESOLOWSKI, Mike
BloodTechNet Award Program 32795.0
Donor characteristics and the quality of red cell concentrates Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: MYKHAILOVA, Olga
Postdoctoral Fellowship Program 165000.0
Optimizing rejuvenation to improve the product quality of pathogen-inactivation and γ-irradiated red cell concentrates Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: QADRI, Syed, SCHUBERT, Peter, DEVINE, Dana
Blood Efficiency Accelerator Program 30000.0
Monovalent Fc receptor blockade using novel fusion proteins: The road towards an IVIg replacement Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: SHEFFIELD, William, BRANCH, Donald
Intramural Research Grant Program 400000.0
Canadian cord blood banking: Legal and policy responses Principal Investigator: CAULFIELD, Timothy

Co-Investigator(s) / Trainee: MURDOCH, Blake, MARCON, Alessandro
James Kreppner Award Program 50000.0
Rapid verification variant D phenotype by genotyping in a regional laboratory Principal Investigator: BERARDI, Philip

Co-Investigator(s) / Trainee: FUNG KEE FUNG, Karen, GIULIVI, Antonio, NEURATH, Doris, CLARKE, Gwen
Blood Efficiency Accelerator Program 30000.0
Blood utilization epidemiological profile to evaluate appropriate use (BLUE) Principal Investigator: ZELLER, Michelle

Co-Investigator(s) / Trainee: ARNOLD, Donald, WEBERT, Kathryn, HEDDLE, Nancy, NING, Shuoyan, BARTY, Rebecca
Blood Efficiency Accelerator Program 29964.0
Investigating a new class of small molecule ice recrystallization inhibitors for red blood cell cryopreservation Principal Investigator: BEN, Robert

Co-Investigator(s) / Trainee: AMPAW, Anna
Graduate Fellowship Program 112333.3
Influence of eryptosis and storage on transfused red cell recovery in sepsis Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: BRANCH, Donald, LIAW, Patricia, HEDDLE, Nancy, QADRI, Syed
Intramural Research Grant Program 283569.0
Informing the distribution of COVID-19 convalescent plasma through implementation of CONCOR-1 in British Columbia Principal Investigator: SHIH, Andrew

Co-Investigator(s) / Trainee: VASARHELYI, Krisztina, MANUSHA, Stephania Anna, STEINER, Ted, MCMASTER, Robert, DALY, Patricia, LI, Na, DOWN, Douglas, HEDDLE, Nancy, PETRASZKO, Tanya, LIOW, Eric, PAVLOVICH, Sasha, RUTHERFORD, Alexander
Blood Efficiency Accelerator Program 30000.0
Feasibility of implementing source plasma donation with alternative eligibility criteria for men who have sex with men Principal Investigator: PRESSEAU, Justin

Co-Investigator(s) / Trainee: GOLDMAN, Mindy, O'BRIEN, Sheila, MACPHERSON, Paul, OTIS, Joanne, GERMAIN, Marc, DEVINE, Dana, ROSSER, Andrew, LAPIERRE, Don
MSM Research Grant Program 309940.0
Optimization of monoclonal anti-erythrocyte antibodies for improved immunoprophylaxis in a murine model Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: NI, Heyu
Intramural Research Grant Program 400000.0
Of skin, sperm, and blood: A comparative analysis of exemptions in Canadian human tissue legislation Principal Investigator: CATTAPAN, Alana

Co-Investigator(s) / Trainee: VON TIGERSTROM, Barbara, NELSON, Eric, DAWSON, Rosanne
James Kreppner Award Program 43275.0
Investigating the mechanism of anti-CD44 antibody amelioration of IVIg-treatable disease Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: NORRIS, Peter
Graduate Fellowship Program 112333.3
Monoclonal antibodies with anti-D like activity in amelioration of murine ITP Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: KHAN, Ramsha
Graduate Fellowship Program 56166.7
Development of internet modules for serology curriculum delivery Principal Investigator: YAN, Matthew

Co-Investigator(s) / Trainee: PENDERGRAST, Jacob, TAIT, Gordon
BloodTechNet Award Program 35500.0
Synthesis of carbohydrate derivatives for the improvement of red blood cell storage Principal Investigator: BEN, Robert

Co-Investigator(s) / Trainee: MEYER, Julia
Graduate Fellowship Program 79500.0
Estimating the probability of HIV risk in MSM donor policies through biobehavioural and mathematical modelling studies Principal Investigator: HART, Trevor

Co-Investigator(s) / Trainee: LAMBERT, Gilles, GRACE, Daniel, BAUER, Greta, MOORE, David, COX, Joseph, LACHOWSKY, Nathan, MISHRA, Sharmistha, BRENNAN, David, TAN, Darrell, SKAKOON-SPARLING, Shayna
MSM Research Grant Program 452500.0
Assessing alternative Canadian Blood Services blood donor deferral screening policies for men who have sex with men Principal Investigator: BRENNAN, David

Co-Investigator(s) / Trainee: ADAM, Barry, HART, Trevor, LACHOWSKY, Nathan, GRACE, Daniel
MSM Research Grant Program 60000.0
Évaluation de l’acceptabilité et de la faisabilité d’un programme de dons de plasma destiné au fractionnement, pour les hommes ayant des relations sexuelles avec d’autres hommes de la communauté gaie montréalaise Principal Investigator: OTIS, Joanne

Co-Investigator(s) / Trainee: GERMAIN, Marc, GODIN, Gaston, PRONOVOST, Frédérick, MONTEITH, Kenneth, MYHAL, Geneviève, GIRARD, Gabriel, MORIN, Michel
MSM Research Grant Program 229507.0
Attitudes, behaviours, and acceptability related to current and future blood donation policy: A qualitative study of gay, bisexual, and other men who have sex with men in Vancouver, Toronto, and Montréal Principal Investigator: GRACE, Daniel

Co-Investigator(s) / Trainee: HART, Trevor, LAMBERT, Gilles, COX, Joseph , ADAM, Barry , BRENNAN, David , LACHOWSKY, Nathan, MOORE, David
MSM Research Grant Program 60000.0
Allowing MSM to donate in the context of pathogen reduction of blood components: mathematical modeling of the risk of HIV, HBV and HCV transmission through transfusion Principal Investigator: LEWIN, Antoine

Co-Investigator(s) / Trainee: GERMAIN, Marc, DELAGE, Gilles, ROBILLARD, Pierre, GRÉGOIRE, Yves, WILLIAM, Fraser
MSM Research Grant Program 39618.0
Novel detection strategies for new platelet ligands and anti-platelet antibodies Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee: NEVES, Miguel
Postdoctoral Fellowship Program 150000.0
Sex Now 2018: A national survey on blood donation and undiagnosed blood borne infections Principal Investigator: LACHOWSKY, Nathan

Co-Investigator(s) / Trainee: TRUSSLER, Terry, GILBERT, Mark, SALWAY, Travis, JOLLIMORE, Jody, HAM, David, LOFTUS, Patrick, OLIVER, Brent, HANSEN, Brian, VISSER, Floyd, BRENNAN, David, GRACE, Daniel, OTIS, Joanne, LEBOUCHÉ, Bertrand, NUMER, Matthew, SAXTON, Peter
MSM Research Grant Program 421719.0
Mathematical Modelling – Comparing HIV Risk Between MSM Donation Strategies Principal Investigator: O'BRIEN, Sheila

Co-Investigator(s) / Trainee: GERMAIN, Marc, GRÉGOIRE, Yves, SEED, Clive, CUSTER, Brian, STEELE, Whitney, DAVISON, Katy, PILLONEL, Josiane
MSM Research Grant Program 24000.0
A novel clot-dissolving agent derived from clotting factor Va Principal Investigator: PRYZDIAL, Ed

Co-Investigator(s) / Trainee: LEE, Frank
Graduate Fellowship Program 39500.0
A program to minimize preventable and inappropriate blood product transfusions in liver surgery Principal Investigator: MARTEL, Guillaume

Co-Investigator(s) / Trainee: BAKER, Laura, TINMOUTH, Alan, SAIDENBERG, Elianna, WHERRETT, Christopher, WORKNEH, Aklile
Blood Efficiency Accelerator Program 20000.0
Platelet desialylation: novel mechanism of platelet clearance and immune tolerance Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee: LI, June
Graduate Fellowship Program 104000.0
Development of a small molecule-based stem and progenitor expansion protocol to accelerate engraftment after cord blood transplantation Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: MANESIA, Javed
Postdoctoral Fellowship Program 101200.0
Transfusion-Related Acute Lung Injury and delayed TRALI: a prospective study in critically ill children Principal Investigator: EMERIAUD, Guillaume

Co-Investigator(s) / Trainee: DU PONT-THIBIDEAU, Genevieve, FONTELA, Patricia S. , GAUVIN, France, GILFOYLE, Elaine, HUTCHISON, James S., LACROIX, Jacques, MENON, Kusum, ROBITAILLE, Nancy, TINMOUTH, Alan T., TROTTIER, Helen
Canadian Blood Services-CIHR Partnership Operating Grant Program 477651.0
Code sepsis: defining and translating optimal resuscitation and care for children with septic shock Principal Investigator: PARKER, Melissa

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership New Investigator Program 300000.0
A multifaceted intervention to optimize red blood cell transfusion practice in two provinces Principal Investigator: WEBERT, Kathryn

Co-Investigator(s) / Trainee: NAHIRNIAK, Susan, CALLUM, Jeannie, LIN, Yulia, ZELLER, Michelle
Intramural Research Grant Program 332942.0
Assessment of the quality of granulocyte concentrates to optimise their use in transfusion therapy Principal Investigator: FERNANDES, Maria

Co-Investigator(s) / Trainee: GIRARD, Melissa, BRANCH, Donald
Blood Efficiency Accelerator Program 30000.0
Plasma versus plasma protein concentrate transfusion for coagulopathic control Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: NI, Heyu
Intramural Research Grant Program 224417.0
Human monoclonal CD44 antibodies as potential IVIg replacements Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: NI, Heyu
Intramural Research Grant Program 336000.0
The role of stakeholder trust in OTDT policy change: public and professional attitudes to ante-mortem interventions in organ donation Principal Investigator: CHANDLER, Jennifer

Co-Investigator(s) / Trainee: McKAY, Lindsey
James Kreppner Award Program 50000.0
An evaluation of learner perspectives and outcomes following completion of the transfusion medicine area of focused competence Principal Investigator: TSENG, Eric Kuo

Co-Investigator(s) / Trainee: ZELLER, Michelle
Qualitative Education Funding 9875.0
Safety, Acceptance, Fairness & Equality (SAFE project): Acceptable risk and donor selection Principal Investigator: DITTO, Blaine

Co-Investigator(s) / Trainee: FERGUSON, Eamonn
MSM Research Grant Program 49412.5
National evaluation of platelet transport bags to reduce wastage Principal Investigator: WEBERT, Kathryn

Co-Investigator(s) / Trainee: CALLUM, Jeannie, LIN, Yulia, LIEBERMAN, Lani, PENDERGRAST, Jacob, CSERTI-GAZDEWICH, Christine
Small Project Funding Program 9740.0
Recombinant Fc multimers to replace IVIG Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: LEWIS, Bonnie
Graduate Fellowship Program 104000.0
Study of the mechanisms implicated in platelets microparticle internalization by blood cells Principal Investigator: BOILARD, Eric

Co-Investigator(s) / Trainee: MARCOUX, Genevieve
Graduate Fellowship Program 104000.0
Process evaluation of the Canadian Blood Services' cord blood bank: managerial and donor perspectives Principal Investigator: DEVINE, Dana

Co-Investigator(s) / Trainee: HAW, Jennie
CIHR Health System Impact Fellowship 46500.0
Operational impact of individual risk assessment options Principal Investigator: O'BRIEN, Sheila

Co-Investigator(s) / Trainee: ROBILLARD, Pierre, GOLDMAN, Mindy, MYHAL, Geneviève
MSM Research Grant Program 168000.0