Our Funded Research Projects
Updated April 2024
| Title Sort ascending | Principal Investigator / Supervisor | Program | Project Start Date | Project End Date | Total $ Awarded |
|---|---|---|---|---|---|
| Monoclonal antibodies with anti-D-like activity in the amelioration of murine immune thrombocytopenia (ITP) | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: SEMPLE, John W., NI, Heyu |
Intramural Research Grant Program | 400000.0 | ||
| Monoclonal antibodies with anti-D like activity in amelioration of murine ITP | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: KHAN, Ramsha |
Graduate Fellowship Program | 56166.7 | ||
| Modulation of biofilm formation, virulence, and antimicrobial resistance by Staphylococcus aureus during platelet storage | Principal Investigator: RAMIREZ-ARCOS, Sandra Co-Investigator(s) / Trainee: SAD, Subash, MAH, Thien-Fah |
Intramural Research Grant Program | 323252.6 | ||
| Modified platelet storage containers to improve quality during storage | Principal Investigator: KIZHAKKEDATHU, Jayachandran Co-Investigator(s) / Trainee: PEREYRA DOS SANTOS, Nicolas |
Graduate Fellowship Program | 52000.0 | ||
| Microfluidic devices to measure the deformability of stored red blood cells | Principal Investigator: MA, Hongshen Co-Investigator(s) / Trainee: SCOTT, Mark D. |
Canadian Blood Services-CIHR Partnership Operating Grant Program | 398301.0 | ||
| Mechanisms of erythrocyte antibody-mediated immune suppression | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: NI, Heyu, SEMPLE, John |
Intramural Research Grant Program | 400000.0 | ||
| Mechanisms of antibody-independent transfusion-related acute lung injury (TRALI) | Principal Investigator: KUEBLER, Wolfgang Co-Investigator(s) / Trainee: SEMPLE, John W. |
Canadian Blood Services-CIHR Partnership Operating Grant Program | 328712.0 | ||
| Mechanisms of anti-αIIb mediated miscarriage in fetal and neonatal alloimmune thrombocytopenia | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: CHEN, Zi Yan |
Graduate Fellowship Program | 52000.0 | ||
| Mechanism of anti-D-like antibody-mediated amelioration of immune thrombocytopenia (ITP) | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: YU, Xiaojie (Ben) |
Postdoctoral Fellowship Program | 106200.0 | ||
| Measurement of heavy metals in donor blood in Canada | Principal Investigator: DEVINE, Dana Co-Investigator(s) / Trainee: SERRANO, Katherine, LEVIN, Elena, MURPHY, Michael, BARAKAUSKAS, Vilte, HADJESFAMDOARI, Narges, ARRIETA, Angele, RICHARDSON-SANCHEZ, Tomas |
Blood Efficiency Accelerator Program | 29971.0 | ||
| McMaster Transfusion Research Program | Principal Investigator: HEDDLE, Nancy Co-Investigator(s) / Trainee: |
Program Support Award for Canadian Transfusion Medicine and Science Research Program | 833333.0 | ||
| McMaster Centre for Transfusion Research | Principal Investigator: ARNOLD, Donald Co-Investigator(s) / Trainee: |
Transfusion Medicine Research Program Support Award | 1303333.5 | ||
| Mathematical Modelling – Comparing HIV Risk Between MSM Donation Strategies | Principal Investigator: O'BRIEN, Sheila Co-Investigator(s) / Trainee: GERMAIN, Marc, GRÉGOIRE, Yves, SEED, Clive, CUSTER, Brian, STEELE, Whitney, DAVISON, Katy, PILLONEL, Josiane |
MSM Research Grant Program | 24000.0 | ||
| Mathematical modeling - comparing HIV risk between MSM donation strategies | Principal Investigator: O'BRIEN, Sheila Co-Investigator(s) / Trainee: GRÉGOIRE, Yves, SEED, Clive, CUSTER, Brian, STEELE, Whitney, DAVISON, Katy, PILLONEL, Josiane |
MSM Research Grant Program | 18000.0 | ||
| Leveraging equity-focused implementation science to evaluate and support the re-integration of men who have sex with men into the blood donation system | Principal Investigator: GOLDMAN, Mindy Co-Investigator(s) / Trainee: VESNAVER, Elisabeth |
CIHR Health System Impact Fellowship | 108500.0 | ||
| Legal and policy strategies to optimize organ donation in Alberta | Principal Investigator: TOEWS, Maeghan Co-Investigator(s) / Trainee: |
James Kreppner Fellowship Program | 150000.0 | ||
| IVIG utilization and its impact on platelet count in pregnant women with moderate thrombocytopenia | Principal Investigator: KHALIFE, Roy Co-Investigator(s) / Trainee: TINMOUTH, Alan, EL-CHAAR, Darine, MACK, Jonathan, KAROVITCH, Alan, FERGUSSON, Dean, WEBERT, Kathryn |
Blood Efficiency Accelerator Program | 22217.3 | ||
| Investigation of pathophysiology, prevention and treatment of murine Transfusion Related Acute Lung Injury (TRALI) | Principal Investigator: SEMPLE, John Co-Investigator(s) / Trainee: McVEY, Mark |
Graduate Fellowship Program | 52000.0 | ||
| Investigating the mechanism of anti-CD44 antibody amelioration of IVIg-treatable disease | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: NORRIS, Peter |
Graduate Fellowship Program | 112333.3 | ||
| Investigating a new class of small molecule ice recrystallization inhibitors for red blood cell cryopreservation | Principal Investigator: BEN, Robert Co-Investigator(s) / Trainee: AMPAW, Anna |
Graduate Fellowship Program | 112333.3 | ||
| Innovative strategies for detection of uncharacterized platelet ligands from blood plasma and autoantibodies in blood | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: SLAVKOVIC, Sladjana |
Postdoctoral Fellowship Program | 162400.0 | ||
| Informing the distribution of COVID-19 convalescent plasma through implementation of CONCOR-1 in British Columbia | Principal Investigator: SHIH, Andrew Co-Investigator(s) / Trainee: VASARHELYI, Krisztina, MANUSHA, Stephania Anna, STEINER, Ted, MCMASTER, Robert, DALY, Patricia, LI, Na, DOWN, Douglas, HEDDLE, Nancy, PETRASZKO, Tanya, LIOW, Eric, PAVLOVICH, Sasha, RUTHERFORD, Alexander |
Blood Efficiency Accelerator Program | 30000.0 | ||
| Influence of eryptosis and storage on transfused red cell recovery in sepsis | Principal Investigator: SHEFFIELD, William Co-Investigator(s) / Trainee: BRANCH, Donald, LIAW, Patricia, HEDDLE, Nancy, QADRI, Syed |
Intramural Research Grant Program | 283569.0 | ||
| Incidence of intracranial hemorrhage in pediatric oncology patients | Principal Investigator: WEBERT, Kathryn Co-Investigator(s) / Trainee: |
Small Project Funding Program | 15000.0 | ||
| IN-TRUST: Using a transfusion database to explore the immune-modulatory impacts of blood transfusion and the clinical impacts of blood processing changes | Principal Investigator: NING, Shuoyan Co-Investigator(s) / Trainee: ARNOLD, Donald, ZELLER, Michelle, ACKER, Jason, LI, Na, HEDDLE, Nancy, HILLIS, Christopher, ROCHWERG, Bram, SYED, Summer |
Intramural Research Grant Program | 270352.1 | ||
| Improving the cryostorage of blood products using novel small molecule cryoprotectants | Principal Investigator: BEN, Robert Co-Investigator(s) / Trainee: ACKER, Jason P. , ALLAN, David S. |
Canadian Blood Services-CIHR Partnership Operating Grant Program | 384180.0 | ||
| Improving pathogen inactivation: the dengue virus-induced platelet proteome | Principal Investigator: PRYZDIAL, Ed Co-Investigator(s) / Trainee: TEGEGN, Tseday Zewdu |
Graduate Fellowship Program | 104000.0 | ||
| Improving blood product quality | Principal Investigator: DEVINE, Dana Co-Investigator(s) / Trainee: MA, Hongshen, JOHNSON, James, D'ALESSANDRO, Angelo |
Intramural Research Grant Program | 304462.0 | ||
| Impact of storage on the function of cord blood hematopoietic stem and progenitor cells | Principal Investigator: PINEAULT, Nicolas Co-Investigator(s) / Trainee: JAHAN, Suria |
Graduate Fellowship Program | 104000.0 | ||
| Identifying biomarkers for Staphylococcus aureus contamination of platelet component | Principal Investigator: RAMIREZ-ARCOS, Sandra Co-Investigator(s) / Trainee: CHI, Sylvia Ighem |
Postdoctoral Fellowship Program | 150000.0 | ||
| Identification of protein biomarkers for red cell quality | Principal Investigator: DEVINE, Dana Co-Investigator(s) / Trainee: CHEN, Deborah |
Graduate Fellowship Program | 100000.0 | ||
| Identification of mechanisms leading to antibody independent RBC hemolysis | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: FRIAS BOLIGAN, Kayluz |
Postdoctoral Fellowship Program | 150000.0 | ||
| Identification of host cellular immune mechanisms responsible for the initiation and/or modulation of Transfusion Related Acute Lung Injury (TRALI) | Principal Investigator: SEMPLE, John Co-Investigator(s) / Trainee: KUEBLER, Wolfgang M. |
Canadian Blood Services-CIHR Partnership Operating Grant Program | 398982.0 | ||
| Hypothermic Storage as an Alternative to Irradiation of Red Cell Concentrates | Principal Investigator: ACKER, Jason Co-Investigator(s) / Trainee: CLARKE, Gwen, NAHIRNIAK, Susan, BRANDON-COATHAM, Mackenzie, OLAFSON, Carly |
Blood Efficiency Accelerator Program | 30000.0 | ||
| Human monoclonal CD44 antibodies as potential IVIg replacements | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: NI, Heyu |
Intramural Research Grant Program | 336000.0 | ||
| Generation of a coagulation factor-based thrombotic agent | Principal Investigator: PRYZDIAL, Ed Co-Investigator(s) / Trainee: WITT, Alexandra |
Graduate Fellowship Program | 52000.0 | ||
| Fetal and neonatal alloimmune thrombocytopenia: novel mechanisms and therapeutic approaches | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: |
Canadian Blood Services-CIHR Partnership Operating Grant Program | 471393.0 | ||
| Feasibility of implementing source plasma donation with alternative eligibility criteria for men who have sex with men | Principal Investigator: PRESSEAU, Justin Co-Investigator(s) / Trainee: GOLDMAN, Mindy, O'BRIEN, Sheila, MACPHERSON, Paul, OTIS, Joanne, GERMAIN, Marc, DEVINE, Dana, ROSSER, Andrew, LAPIERRE, Don |
MSM Research Grant Program | 309940.0 | ||
| Feasibility in Canada for a non-invasive prenatal testing using single-exon fetal RHD determination | Principal Investigator: ACKER, Jason Co-Investigator(s) / Trainee: CLARKE, Gwen, BHATTI, Aniqa |
Blood Efficiency Accelerator Program | 20000.0 | ||
| Fc receptors and IVIg in ITP | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: CSERTI-GAZDEWICH, Christine, LIN, Yulia, CALLUM, Jeannie, SHOLZBERG, Michelle, NI, Heyu |
Intramural Research Grant Program | 432000.0 | ||
| Fc receptor blockade related to fetal and neonatal alloimmune thrombocytopenia | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: TAWHIDI, Zoya |
Graduate Fellowship Program | 70000.0 | ||
| Fc receptor blockade in transfusion medicine | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: NI, Heyu, GUPTA, Akash, SHEHATA, Nadine, KJELDSEN-KRAGH, Jens, NEWMAN, Peter J., CSERTI-GAZDEWICH, Christine, RAVETCH, Jeffery |
Intramural Research Grant Program | 400000.0 | ||
| Exploratory analyses to determine if method of donor blood processing affects outcome in transfused recipients | Principal Investigator: HEDDLE, Nancy Co-Investigator(s) / Trainee: ACKER, Jason P. , ARNOLD, Donald M. , COOK, Richard J. , EIKELBOOM, John W. , O'BRIEN, Sheila F. , WEBERT, Kathryn E. |
Canadian Blood Services-CIHR Partnership Operating Grant Program | 159878.0 | ||
| Expanding treatment options for inflammatory bowel disease: A novel mechanism of antibody-based immunotherapy | Principal Investigator: SLY, Laura Co-Investigator(s) / Trainee: HORWITZ, Marc, BRESSLER, Brian, RASSEKH, Rod, TURVEY, Stuart |
Canadian Blood Services-CIHR Partnership Operating Grant Program | 408540.6 | ||
| Examining the relationship between repeated blood donations in female donors on maternal/neonatal outcomes: a cohort study | Principal Investigator: TINMOUTH, Alan Co-Investigator(s) / Trainee: CHASSE, Michael, FERGUSSON, Dean A., GOLDMAN, Mindy R., O'BRIEN, Sheila F., SPRAGUE, Ann, van WALRAVEN, Carl, WALKER, Mark C., WILSON, Kumanan |
Canadian Blood Services-CIHR Partnership Operating Grant Program | 135657.0 | ||
| Évaluation de l’acceptabilité et de la faisabilité d’un programme de dons de plasma destiné au fractionnement, pour les hommes ayant des relations sexuelles avec d’autres hommes de la communauté gaie montréalaise | Principal Investigator: OTIS, Joanne Co-Investigator(s) / Trainee: GERMAIN, Marc, GODIN, Gaston, PRONOVOST, Frédérick, MONTEITH, Kenneth, MYHAL, Geneviève, GIRARD, Gabriel, MORIN, Michel |
MSM Research Grant Program | 229507.0 | ||
| Evaluation and improvement of cold stored platelets | Principal Investigator: DEVINE, Dana Co-Investigator(s) / Trainee: ZHAO, Hanqi (Wayne) |
Graduate Fellowship Program | 112333.3 | ||
| Evaluating unintentional warming of glycerolized red cell concentrates | Principal Investigator: ACKER, Jason Co-Investigator(s) / Trainee: CLARKE, Gwen, TURNER, Tracy, OLAFSON, Carly, MYKHAILOVA, Olga |
Blood Efficiency Accelerator Program | 25000.0 | ||
| Evaluating transfusion medicine patterns of practice across GEMINI sites | Principal Investigator: CALLUM, Jeannie Co-Investigator(s) / Trainee: ARNOLD, Donald, VERMA, Amol, SRIVASTAVA, Siddhartha, CHENG, Calvino, ESMAIL, Tariq, DESVEAUX, Laura, TYRYSHKIN, Kathrin, KARKOUTI, Keyvan, LADHA, Karim, LI, Na, PAVENSKI, Katerina, PENDERGRAST, Jacob, PRESSEAU, Justin, SCHNEIDER, Henry, SHEHATA, Nadine, SHIH, Andrew, THIRUMURTHY, Harsha, BREHAUT, Jamie, RAZAK, Fahad, MCLCEARY, Nicola, ZUCKERMAN, Jesse |
Kenneth J. Fyke Award Program | 98822.0 | ||
| Evaluating the role of donor characteristics and blood component manufacturing on the quality of red cell concentrates | Principal Investigator: ACKER, Jason Co-Investigator(s) / Trainee: BRANCH, Donald, CLARKE, Gwen, NAHIRNIAK, Susan |
Intramural Research Grant Program | 398382.8 |