Our Research Publications
Updated November 2023
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Title Sort descending | Authors | Year | Journal | Link to Article | Intended Audience | Purpose |
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ResearchUnit: Red cell irradiation - time for a change? | Serrano K | 2014 | Blood.ca website | View ResearchUnit: Red cell irradiation - time for a change? | Other | Other |
ResearchUnit: Reducing bleeding after cardiac surgery: fibrinogen concentrate vs cryoprecipitate | Karkouti K | 2020 | Blood.ca website | View ResearchUnit: Reducing bleeding after cardiac surgery: fibrinogen concentrate vs cryoprecipitate | Health care providers | Clinical research |
ResearchUnit: Research into TRALI therapies gene therapy results that are a TAD interesting! | Semple J | 2014 | Blood.ca website | View ResearchUnit: Research into TRALI therapies gene therapy results that are a TAD interesting! | Other | Other |
ResearchUnit: Risk of HIV did not change with expanding eligibility criteria for gay, bisexual and other men who have sex with men | Walsh G | 2022 | Blood.ca website | View ResearchUnit: Risk of HIV did not change with expanding eligibility criteria for gay, bisexual and other men who have sex with men | Regulators | MSM research |
ResearchUnit: Searching for safer red blood cell bags for pediatric recipients | Serrano K, Acker J | 2016 | Blood.ca website | View ResearchUnit: Searching for safer red blood cell bags for pediatric recipients | Other | Other |
ResearchUnit: Sex-mismatched red blood cell transfusions and mortality | Zeller M | 2019 | Blood.ca website | View ResearchUnit: Sex-mismatched red blood cell transfusions and mortality | Health care providers | Clinical research |
ResearchUnit: Sexual behaviour-based screening questions: Understanding and mitigating donor discomfort | Woo H | 2022 | Blood.ca website | View ResearchUnit: Sexual behaviour-based screening questions: Understanding and mitigating donor discomfort | Blood operators | MSM research |
ResearchUnit: Should patients receive HLA-selected platelets? | Shehata N | 2013 | Blood.ca website | View ResearchUnit: Should patients receive HLA-selected platelets? | Other | Other |
ResearchUnit: Single site solution: engineering novel antibodies for the treatment of ITP | Lazarus A | 2015 | Blood.ca website | View ResearchUnit: Single site solution: engineering novel antibodies for the treatment of ITP | Other | Other |
ResearchUnit: Supporting evidence to change regulations regarding the storage of cryosupernatant plasma. | Sheffield W | 2013 | Blood.ca website | View ResearchUnit: Supporting evidence to change regulations regarding the storage of cryosupernatant plasma. | Other | Other |
ResearchUnit: Treating bleeding during cardiac surgery: Is prothrombin complex concentrate a substitute for plasma? | Kron A | 2021 | Blood.ca website | View ResearchUnit: Treating bleeding during cardiac surgery: Is prothrombin complex concentrate a substitute for plasma? | Health care providers | Clinical research |
ResearchUnit: Treatment and detection of vaccine-induced thrombotic thrombocytopenia (VITT) | Abe T | 2021 | Blood.ca website | View ResearchUnit: Treatment and detection of vaccine-induced thrombotic thrombocytopenia (VITT) | Health care providers | Clinical research |
ResearchUnit: United we stand, divided we fall: using monoclonal antibody combinations to improve drug effectiveness | Lazarus A | 2016 | Blood.ca website | View ResearchUnit: United we stand, divided we fall: using monoclonal antibody combinations to improve drug effectiveness | Other | Other |
ResearchUnit: Using Immunocamouflage to Fool the Immune System | Scott MD | 2015 | Blood.ca website | View ResearchUnit: Using Immunocamouflage to Fool the Immune System | Other | Other |
ResearchUnit: Using immunocamouflage to increase transplantation safety | Scott M | 2017 | Blood.ca website | View ResearchUnit: Using immunocamouflage to increase transplantation safety | Other | Other |
ResearchUnit: What if the shelf life of red blood cells was less than 42 days? | Blake J | 2013 | Blood.ca website | View ResearchUnit: What if the shelf life of red blood cells was less than 42 days? | Other | Other |
ResearchUnit: What is the risk of a transfusion-transmitted infection? | O'Brien S | 2013 | Blood.ca website | View ResearchUnit: What is the risk of a transfusion-transmitted infection? | Other | Other |
ResearchUnit: What is the utility of selecting platelets by cross-matching? | Shehata N | 2013 | Blood.ca website | View ResearchUnit: What is the utility of selecting platelets by cross-matching? | Other | Other |
ResearchUnit: Where is the blood going? Understanding red blood cell utilization to inform policies | Zeller M, Heddle N, Devine D | 2017 | Blood.ca website | View ResearchUnit: Where is the blood going? Understanding red blood cell utilization to inform policies | Other | Other |
ResearchUnit: Whole blood: longer holding times before leukoreduction may be a safe to explore option | Chen ZY | 2022 | Blood.ca website | View ResearchUnit: Whole blood: longer holding times before leukoreduction may be a safe to explore option | Regulators | New or improved product or process |
Residual risk of bacterial contamination of platelets: six years of experience with sterility testing | Ramirez-Arcos S, DiFranco C, McIntyre T, Goldman M | 2017 | Transfusion | View Residual risk of bacterial contamination of platelets: six years of experience with sterility testing | Researchers | New or improved product or process |
Residual Risk of HIV, HCV and HBV in Canada | O'Brien SF, Yi Q-L, Fan W, Scalia V, Goldman M, Fearon MA | 2017 | Transfus Apher Sci | View Residual Risk of HIV, HCV and HBV in Canada | Health care providers | Clinical research |
Resistance of SARS-CoV-2 beta and gamma variants to plasma collected from Canadian blood donors during the spring of 2020 | Drews SJ, Abe KT, Hu Q, Samson R, Gingras A-C, Colwill K, Rathod B, Wang J, Fazel-Zarandi M, Yi Q-L, Robinson A, Wood H, Tuite A, Fisman D, Evans DH, Lin Y-CJ, O'Brien SF | 2022 | Transfusion | View Resistance of SARS-CoV-2 beta and gamma variants to plasma collected from Canadian blood donors during the spring of 2020 | Researchers | Clinical research |
Resolving variable maternal D typing using serology and genotyping in selected prenatal patients | Clarke G, Hannon J, Berardi P, Barr G, Cote J, Fallis R, Alport T, Lane D, Petraszko T, Ochoa G, Goldman M | 2016 | Transfusion | View Resolving variable maternal D typing using serology and genotyping in selected prenatal patients | Health care providers | New or improved product or process |
Response to ‘Adverse cardiac outcomes in patients with chronic myeloid leukaemia treated with tyrosine kinase inhibitors’ | Leong D, Hillis C, Aghel N, Pond G, Seow H | 2021 | Heart | View Response to ‘Adverse cardiac outcomes in patients with chronic myeloid leukaemia treated with tyrosine kinase inhibitors’ | Researchers | Clinical research |
Restrictive or liberal red-cell transfusion for cardiac surgery | Mazer CD, Whitlock RP, Fergusson DA, Hall J, Belley-Cote E, Connolly K, Khanykin B, Gregory AJ, de Medicis E, McGuinness S, Royse A, Carrier FM, Young PJ, Villar JC, Grocott HP, Seeberger MD, Fremes S, Lellouche F, Syed S, Byrne K, Bagshaw SM, Hwang NC, Mehta C, Painter TW, Royse C, Verma S, Hare GMT, Cohen A, Thorpe KE, Juni P, Shehata N | 2017 | N Engl J Med | View Restrictive or liberal red-cell transfusion for cardiac surgery | Health care providers | Clinical research |
Restrictive versus liberal red blood cell transfusion strategies for people with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem cell support | Estcourt LJ, Malouf R, Trivella M, Fergusson DA, Hopewell S, Murphy MF | 2017 | Cochrane Database Syst Rev | View Restrictive versus liberal red blood cell transfusion strategies for people with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem cell support | Health care providers | Clinical research |
Retention of hemostatic and immunological properties of frozen plasma and COVID-19 convalescent apheresis fresh-frozen plasma produced and freeze-dried in Canada | Sheffield WP, Bhakta V, Howell A, Jenkins C, Serrano K, Johnson N, Lin Y-CJ, Colwill K, Rathod B, Greenberg B, Gingras A-C, Evans DH, Flaumenhaft E, Beckett A, Drews SJ, Devine DV | 2022 | Transfusion | View Retention of hemostatic and immunological properties of frozen plasma and COVID-19 convalescent apheresis fresh-frozen plasma produced and freeze-dried in Canada | Researchers | Basic research |
Retention of thrombin inhibitory activity by recombinant serpins expressed as integral membrane proteins tethered to the surface of mammalian cells | Gierczak RF, Sutherland JS, Bhakta V, Toltl LJ, Liaw PC, Sheffield WP | 2011 | J Thromb Haemost | View Retention of thrombin inhibitory activity by recombinant serpins expressed as integral membrane proteins tethered to the surface of mammalian cells | Researchers | Basic research |
Rethinking platelet transfusion practices | Devine DV | 2021 | Blood | View Rethinking platelet transfusion practices | Health care providers | New or improved product or process |
Revealing the diversity of extracellular vesicles using high-dimensional flow cytometry analyses | Marcoux G, Duchez A-C, Cloutier N, Provost P, Nigrovic PA, Boilard E | 2016 | Sci Rep | View Revealing the diversity of extracellular vesicles using high-dimensional flow cytometry analyses | Researchers | Basic research |
Reversible hemostatic properties of sulfabetaine/quaternary ammonium modified hyperbranched polyglycerol | Wen J, Weinhart M, Lai B, Kizhakkedathu J, Brooks DE | 2016 | Biomaterials | View Reversible hemostatic properties of sulfabetaine/quaternary ammonium modified hyperbranched polyglycerol | Researchers | Basic research |
Revisiting study design and methodology for pathogen reduced platelet transfusions: a round table discussion | Heddle NM, Cardoso M, van der Meer PF | 2020 | Transfusion | View Revisiting study design and methodology for pathogen reduced platelet transfusions: a round table discussion | Researchers | Clinical research |
Rh System: Anti-Cw | Meunier D, Peng S, Clarke G | 2019 | Blood.ca website | View Rh System: Anti-Cw | Health care providers | Benchmarking and standard setting |
Rh System: Anti-V | Meunier D, Peng S, Clarke G | 2019 | Blood.ca website | View Rh System: Anti-V | Health care providers | Benchmarking and standard setting |
RhD Specific Antibodies Are Not Detectable in HLA-DRB1(*)1501 Mice Challenged with Human RhD Positive Erythrocytes | Bernardo L, Denomme GA, Shah K, Lazarus AH | 2014 | Adv Hematol | View RhD Specific Antibodies Are Not Detectable in HLA-DRB1(*)1501 Mice Challenged with Human RhD Positive Erythrocytes | Researchers | Basic research |
RhoA/ROCK signaling contributes to sex differences in the activation of human platelets | Schubert P, Coupland D, Nombalais M, Walsh G, Devine DV | 2016 | Thromb Res | View RhoA/ROCK signaling contributes to sex differences in the activation of human platelets | Researchers | Basic research |
Riboflavin and ultraviolet illumination affects selected platelet mRNA transcript amounts differently | Klein-Bosgoed C, Schubert P, Devine DV | 2016 | Transfusion | View Riboflavin and ultraviolet illumination affects selected platelet mRNA transcript amounts differently | Researchers | Basic research |
Riboflavin and ultraviolet light treatment of platelets triggers p38MAPK signaling: inhibition significantly improves in vitro platelet quality after pathogen reduction treatment | Schubert P, Coupland D, Culibrk B, Goodrich RP, Devine DV | 2013 | Transfusion | View Riboflavin and ultraviolet light treatment of platelets triggers p38MAPK signaling: inhibition significantly improves in vitro platelet quality after pathogen reduction treatment | Researchers | Basic research |
Riboflavin and ultraviolet light treatment potentiates vasodilator-stimulated phosphoprotein Ser-239 phosphorylation in platelet concentrates during storage | Schubert P, Culibrk B, Coupland D, Scammell K, Gyongyossy-Issa M, Devine DV | 2012 | Transfusion | View Riboflavin and ultraviolet light treatment potentiates vasodilator-stimulated phosphoprotein Ser-239 phosphorylation in platelet concentrates during storage | Researchers | Basic research |
rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and Fc?Rs | Spirig R, Campbell IK, Koernig S, Chen C-G, Lewis BJB, Butcher R, Muir I, Taylor S, Chia J, Leong D, Simmonds J, Scotney P, Schmidt P, Fabri L, Hofmann A, Jordi M, Spycher MO, Cattepoel S, Brasseit J, Panousis C, Rowe T, Branch DR, Baz Morelli A, Kaesermann F, Zuercher AW | 2018 | J Immunol | View rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and Fc?Rs | Researchers | Basic research |
rIgG1 Fc hexamer inhibits antibody-mediated autoimmune disease via effects on complement and FcgammaRs | Spirig R, Campbell IK, Koernig S, Chen CG, Lewis BJB, Butcher R, Muir I, Taylor S, Chia J, Leong D, Simmonds J, Scotney P, Schmidt P, Fabri L, Hofmann A, Jordi M, Spycher MO, Cattepoel S, Brasseit J, Panousis C, Rowe T, Branch DR, Baz Morelli A, Kasermann F, Zuercher AW | 2018 | J Immunol | View rIgG1 Fc hexamer inhibits antibody-mediated autoimmune disease via effects on complement and FcgammaRs | Researchers | Basic research |
Rights and interests in human bodies and biological materials | Toews M, Caulfield T, Nelson E, Ogbogu U, Hartell D | 2015 | Canadian National Transplant Research Program Fast Policy Facts: Human Bodies and Biological Materials | View Rights and interests in human bodies and biological materials | Other | Other |
Risk analysis of transfusion of cryoprecipitate without consideration of ABO group | Hadjesfandiari N, Levin E, Serrano K, Yi Q-L, Devine DV | 2021 | Transfusion | View Risk analysis of transfusion of cryoprecipitate without consideration of ABO group | Health care providers | Benchmarking and standard setting |
Risk factors and impact of major bleeding in critically ill patients receiving heparin thromboprophylaxis | Lauzier F, Arnold DM, Rabbat C, Heels-Ansdell D, Zarychanski R, Dodek P, Ashley BJ, Albert M, Khwaja K, Ostermann M, Skrobik Y, Fowler R, McIntyre L, Nates JL, Karachi T, Lopes RD, Zytaruk N, Finfer S, Crowther M, Cook D | 2013 | Intensive Care Med | View Risk factors and impact of major bleeding in critically ill patients receiving heparin thromboprophylaxis | Health care providers | Clinical research |
Risk factors for bleeding in people living with hemophilia A and B treated with regular prophylaxis: A systematic review of the literature | Germini F, Noronha N, Abraham Philip B, Olasupo O, Pete D, Navarro T, Keepanasseril A, Matino D, de Wit K, Parpia S, Iorio A | 2022 | J Thromb Haemost | View Risk factors for bleeding in people living with hemophilia A and B treated with regular prophylaxis: A systematic review of the literature | Researchers | Clinical research |
Risk factors for neonatal thrombosis: A retrospective study conducted in a single Canadian intensive care unit | Bhatia K, Solanki S, Paes B, Chan AKC, Bhatt MD | 2022 | Pediatr Blood Cancer | View Risk factors for neonatal thrombosis: A retrospective study conducted in a single Canadian intensive care unit | Researchers | Clinical research |
Risk infection to spare bleeding? The quandary of splenectomy for immune thrombocytopenia | Zeller M, Arnold DM | 2015 | Am J Hematol | View Risk infection to spare bleeding? The quandary of splenectomy for immune thrombocytopenia | Health care providers | Clinical research |
Risk of acute kidney injury in patients randomized to a restrictive versus liberal approach to red blood cell transfusion in cardiac surgery: a substudy protocol of the transfusion requirements in cardiac surgery III noninferiority trial | Garg AX, Shehata N, McGuinness S, Whitlock R, Fergusson D, Wald R, Parikh C, Bagshaw SM, Khanykin B, Gregory A, Syed S, Hare GMT, Cuerden MS, Thorpe KE, Hall J, Verma S, Roshanov PS, Sontrop JM, Mazer CD | 2018 | Can J Kidney Health Dis | View Risk of acute kidney injury in patients randomized to a restrictive versus liberal approach to red blood cell transfusion in cardiac surgery: a substudy protocol of the transfusion requirements in cardiac surgery III noninferiority trial | Researchers | Clinical research |
Risk of exposure to blood products during pregnancy: guidance for Zika and other donor deferral policies | Murphy MS, Shehata N, Colas JA, Chassé M, Fergusson DA, O'Brien SF, Goldman M, Tinmouth A, Forster AJ, Wilson K | 2017 | Transfusion | View Risk of exposure to blood products during pregnancy: guidance for Zika and other donor deferral policies | Health care providers | Clinical research |