Platelet Allo Immunization Investigation

Test description

Platelet refractoriness is defined as a poor response (no increase in the post transfusion platelet increment) following a platelet transfusion. The cause of refractoriness may be immune or non-immune in nature. Both HLA and HPA antibodies have been implicated in patients' lack of response to platelet transfusions. Investigation may include HLA and HPA antibody testing as well as HLA and HPA genotyping of the patient.

Platelet Allo Immunization Investigation (PDF)

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