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Improving the usefulness of a laboratory tool to match donors and patients

What is this research about?

Exposure to cells or tissues that are genetically different to your own, for example through blood transfusion, a tissue or organ transplant, or pregnancy, comes with a risk. If the immune system identifies these cells and tissues as foreign, it will mount an immune response against the transfused or transplanted cells or tissues. To avoid these serious reactions, the blood and tissue type of recipients and donors is determined before transfusion or transplantation. To ensure compatibility, cross-matching can also be done, using laboratory tests to determine if a specific donor is compatible with a specific recipient.

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