Nos projets de recherche
Disponible en anglais seulement
Mise à jour septembre 2023
| Title | Principal Investigator / Supervisor | Program Trier par ordre décroissant | Project Start Date | Project End Date | Total $ Awarded |
|---|---|---|---|---|---|
| Fc receptor blockade related to fetal and neonatal alloimmune thrombocytopenia | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: TAWHIDI, Zoya |
Graduate Fellowship Program | 70000.0 | ||
| Investigating the mechanism of anti-CD44 antibody amelioration of IVIg-treatable disease | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: NORRIS, Peter |
Graduate Fellowship Program | 112333.3 | ||
| Perioperative transfusion threshold : A population-based observational study | Principal Investigator: FERGUSSON, Dean Co-Investigator(s) / Trainee: VERRET, Michael |
Graduate Fellowship Program | 52000.0 | ||
| Assessment of fluorinated ice crystallization inhibitors: cryopreservation of hematopoietic stem cells and red blood cells | Principal Investigator: BEN, Robert Co-Investigator(s) / Trainee: BRIARD, Jennie |
Graduate Fellowship Program | 96000.0 | ||
| Small molecule inhibitors of phagocytosis to replace intravenous immunoglobulin (IVIG) | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: TONG, Tik Nga (Cindy) |
Graduate Fellowship Program | 52000.0 | ||
| Investigating a new class of small molecule ice recrystallization inhibitors for red blood cell cryopreservation | Principal Investigator: BEN, Robert Co-Investigator(s) / Trainee: AMPAW, Anna |
Graduate Fellowship Program | 112333.3 | ||
| Donor factors and product quality | Principal Investigator: ACKER, Jason Co-Investigator(s) / Trainee: YAZDANBAKHSH, Mahsa |
Graduate Fellowship Program | 122000.0 | ||
| Identification of protein biomarkers for red cell quality | Principal Investigator: DEVINE, Dana Co-Investigator(s) / Trainee: CHEN, Deborah |
Graduate Fellowship Program | 100000.0 | ||
| Recombinant Fc multimers to replace IVIG | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: LEWIS, Bonnie |
Graduate Fellowship Program | 104000.0 | ||
| Evaluation and improvement of cold stored platelets | Principal Investigator: DEVINE, Dana Co-Investigator(s) / Trainee: ZHAO, Hanqi (Wayne) |
Graduate Fellowship Program | 112333.3 | ||
| Mechanisms of anti-αIIb mediated miscarriage in fetal and neonatal alloimmune thrombocytopenia | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: CHEN, Zi Yan |
Graduate Fellowship Program | 52000.0 | ||
| The in vivo effects of liposome treatment on minimizing membrance injury in rat red blood cells during hypothermic storage | Principal Investigator: HOLOVATI, Jelena Co-Investigator(s) / Trainee: da SILVIERA CAVALCANTE, Luciana |
Graduate Fellowship Program | 100000.0 | ||
| Study of the mechanisms implicated in platelets microparticle internalization by blood cells | Principal Investigator: BOILARD, Eric Co-Investigator(s) / Trainee: MARCOUX, Genevieve |
Graduate Fellowship Program | 104000.0 | ||
| Anti-GPIb mediated thrombocytopenia: implications for IVIG and other therapies | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: XU, Miao |
Graduate Fellowship Program | 52000.0 | ||
| Defining the stem cell regulatory functions of GAS6 and FTO | Principal Investigator: MAGANTI, Harinad Co-Investigator(s) / Trainee: PASALA, Ajay |
Graduate Fellowship Program | 52000.0 | ||
| MRI guided focused ultrasound facilitated IVIg immunotherapy as a therapeutic approach for Alzheimer's disease | Principal Investigator: AUBERT, Isabelle Co-Investigator(s) / Trainee: DUBEY, Sonam |
Graduate Fellowship Program | 100000.0 | ||
| Dengue virus replication by anucleate cells: impact on pathogen reduction efficacy | Principal Investigator: PRYZDIAL, Ed Co-Investigator(s) / Trainee: FELGENHAUER, Ulrike |
Graduate Fellowship Program | 52000.0 | ||
| Deformability based cell sorting enabling quality control of stored red blood cells | Principal Investigator: MA, Hongshen Co-Investigator(s) / Trainee: ISLAMZADA, Emel |
Graduate Fellowship Program | 112333.0 | ||
| Generation of a coagulation factor-based thrombotic agent | Principal Investigator: PRYZDIAL, Ed Co-Investigator(s) / Trainee: WITT, Alexandra |
Graduate Fellowship Program | 52000.0 | ||
| Role of skin disinfection and buffy coat platelet production on residual bacterial contamination in platelet concentrates and cord blood stem cells | Principal Investigator: RAMIREZ-ARCOS, Sandra Co-Investigator(s) / Trainee: TAHA, Mariam |
Graduate Fellowship Program | 92000.0 | ||
| Platelet desialylation: novel mechanism of platelet clearance and immune tolerance | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: LI, June |
Graduate Fellowship Program | 104000.0 | ||
| A novel clot-dissolving agent derived from clotting factor Va | Principal Investigator: PRYZDIAL, Ed Co-Investigator(s) / Trainee: LEE, Frank |
Graduate Fellowship Program | 39500.0 | ||
| Assessing the relationship between red blood cell deformability and transfusion lifetime | Principal Investigator: MA, Hongshen Co-Investigator(s) / Trainee: LAMOUREUX, Erik |
Graduate Fellowship Program | 52000.0 | ||
| Characterization of the role of MSI2 in human hematopoietic stem cell self-renewal | Principal Investigator: HOPE, Kristin Co-Investigator(s) / Trainee: RENTAS, Stefan |
Graduate Fellowship Program | 100000.0 | ||
| Small molecule ice recrystallization inhibitors as cryo-additives for red blood cell cryopreservation | Principal Investigator: BEN, Robert Co-Investigator(s) / Trainee: POISSON, Jessica |
Graduate Fellowship Program | 82000.0 | ||
| Enabling next generation hematopoietic-based therapeutics and manufacturing | Principal Investigator: PINEAULT, Nicolas Co-Investigator(s) / Trainee: MCCOMB, Scott, JEZIERSKI, Anna, MAGALHAES, Ana, IQBAL, Umer |
Intramural Research Grant Program | 300000.0 | ||
| Biomarkers in patients with anemia-induced thrombocytopenic bleeding (BAIT): A pilot study | Principal Investigator: ARNOLD, Donald Co-Investigator(s) / Trainee: WEBERT, Kathryn, LIAW, Patricia, BERG, Tobias, HEDDLE, Nancy |
Intramural Research Grant Program | 200000.0 | ||
| Evaluating the role of donor characteristics and blood component manufacturing on the quality of red cell concentrates | Principal Investigator: ACKER, Jason Co-Investigator(s) / Trainee: BRANCH, Donald, CLARKE, Gwen, NAHIRNIAK, Susan |
Intramural Research Grant Program | 398382.8 | ||
| Assessing the impact of donor manufacturing characteristics on survival of transfused red blood cells | Principal Investigator: TINMOUTH, Alan Co-Investigator(s) / Trainee: ACKER, Jason, FERGUSSON, Dean, CHASSÉ, Michaël |
Intramural Research Grant Program | 90935.0 | ||
| A clinical comparison of cold-stored and room temperature-stored allogeneic platelet transfusions in bleeding adult cardiac surgery patients - A randomized multicentre pilot study (PLTS-1 study) | Principal Investigator: BARTOSZKO, Justyna Co-Investigator(s) / Trainee: CALLUM, Jeannie, DEVINE, Dana, KARKOUTI, Keyvan, KAHR, Walter, MCVEY, Mark, PEER, Miki, RAO, Vivek, ABRAHAMYAN, Lusine, LIEBERMAN, Lani, MEWHORT, Holly |
Intramural Research Grant Program | 242617.0 | ||
| TAD-POL (Transfusion-Associated-Dyspnea: Prospective observation and laboratory assessment) | Principal Investigator: CSERTI-GAZDEWICH, Christine Co-Investigator(s) / Trainee: BRANCH, Donald, LAZARUS, Alan, CALLUM, Jeannie, LIN, Yulia, PENDERGRAST, Jacob, LIEBERMAN, Lani, SHEHATA, Nadine, PAVENSKI, Katerina, SKEATE, Robert |
Intramural Research Grant Program | 278027.5 | ||
| Development of porcine equivalent RCC and plasma units for translatable ex vivo organ perfusion research | Principal Investigator: ACKER, Jason Co-Investigator(s) / Trainee: FREED, Darren |
Intramural Research Grant Program | 121834.0 | ||
| Fc receptor blockade in transfusion medicine | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: NI, Heyu, GUPTA, Akash, SHEHATA, Nadine, KJELDSEN-KRAGH, Jens, NEWMAN, Peter J., CSERTI-GAZDEWICH, Christine, RAVETCH, Jeffery |
Intramural Research Grant Program | 400000.0 | ||
| Development of a small molecule cocktail for the expansion of cord blood stem cells | Principal Investigator: PINEAULT, Nicolas Co-Investigator(s) / Trainee: BLAKE, John, AUDET, Julie |
Intramural Research Grant Program | 237600.0 | ||
| PREMISE: Point-of-care hemoglobin accuracy and transfusion outcomes in non-cardiac surgery | Principal Investigator: MARTEL, Guillaume Co-Investigator(s) / Trainee: TINMOUTH, Alan, FERGUSSON, Dean, MCISAAC, Daniel, SHAW, Julie, RAMSAY, Tim, PRESSEAU, Justin, WHERRETT, Christopher, CARRIER, François-Martin, SEELY, Andrew, BRYSON, Gregory |
Intramural Research Grant Program | 392974.0 | ||
| Small molecule inhibitors of phagocytosis | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: KOTRA, Lakshmi P. |
Intramural Research Grant Program | 399130.0 | ||
| Monoclonal antibodies with anti-D-like activity in the amelioration of murine immune thrombocytopenia (ITP) | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: SEMPLE, John W., NI, Heyu |
Intramural Research Grant Program | 400000.0 | ||
| Plasma transfusion or plasma protein product infusion in a murine model of trauma | Principal Investigator: SHEFFIELD, William Co-Investigator(s) / Trainee: PRYZDIAL, Edward |
Intramural Research Grant Program | 257414.8 | ||
| Anti-RBC monoclonal antibodies as a replacement for IVIg and anti-D in ITP | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: BRANCH, Donald, DUNN, Shannon |
Intramural Research Grant Program | 400000.0 | ||
| Can pre-operative anemia be timely identified and optimized in patients awaiting primary arthroplasty surgery? A randomized clinical trial | Principal Investigator: GRAMMATOPOULOS, George Co-Investigator(s) / Trainee: FERGUSSON, Dean, RAMSAY, Tim, TINMOUTH, Alan, GAGNE, Sylvain, MACK, Johnathan, BELZILE, Etienne, BEALE, Paul, THAVORN, Kednapa, TOUCHIE, Donna, GERMAIN, Genevieve, LAROCHE, Vincent |
Intramural Research Grant Program | 276081.0 | ||
| Role of blood component manufacturing on microvesicle-induced transfusion-related immune modulation | Principal Investigator: ACKER, Jason Co-Investigator(s) / Trainee: HOLOVATI, Jelena, BRANCH, Donald, ZHANG, Haibo |
Intramural Research Grant Program | 250660.0 | ||
| Small molecule drug development of phagocytosis inhibitors | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: KOTRA, Lakshmi, P. |
Intramural Research Grant Program | 428468.4 | ||
| Translating novel clotting factor X function to treat thrombosis | Principal Investigator: PRYZDIAL, Ed Co-Investigator(s) / Trainee: MACVICAR, Brian, SHEFFIELD, William |
Intramural Research Grant Program | 369052.0 | ||
| Antibodies to CD44 as a potential replacement for IVIg in ITP | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: SEMPLE, John W., SHEFFIELD, William |
Intramural Research Grant Program | 300000.0 | ||
| Human monoclonal CD44 antibodies as potential IVIg replacements | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: NI, Heyu |
Intramural Research Grant Program | 336000.0 | ||
| Anti-GPIb- and anti-GPIIbIIIa- mediated immune thrombocytopenia: Mechanisms and actions of intravenous IgG (IVIG) and alternative therapies | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: LAZARUS, Alan, BRANCH, Donald |
Intramural Research Grant Program | 412010.3 | ||
| Revisiting the universal donor: Does exposure to O blood products affect patient outcomes? | Principal Investigator: ARNOLD, Donald Co-Investigator(s) / Trainee: ACKER, Jason, BUCKSTEIN, Rena, CALLUM, Jeannie, COOK, Richard, HEDDLE, Nancy, SOLH, Ziad, WEBERT, Kathryn, BARTY, Rebecca, LEBER, Brian, LALIT, Saini |
Intramural Research Grant Program | 378365.0 | ||
| Residual risk of transfusion-transmitted cytomegalovirus infection: incidence and pathogenesis | Principal Investigator: PREIKSAITIS, Jutta Co-Investigator(s) / Trainee: O'BRIEN, Sheila F., FEARON, Margaret, NAHIRNIAK, Susan |
Intramural Research Grant Program | 260451.0 | ||
| Plasma versus plasma protein concentrate transfusion for coagulopathic control | Principal Investigator: SHEFFIELD, William Co-Investigator(s) / Trainee: NI, Heyu |
Intramural Research Grant Program | 224417.0 | ||
| Fc receptors and IVIg in ITP | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: CSERTI-GAZDEWICH, Christine, LIN, Yulia, CALLUM, Jeannie, SHOLZBERG, Michelle, NI, Heyu |
Intramural Research Grant Program | 432000.0 |