Our Research Publications

Updated August 2025

Title Authors Year Journal Link to Article Intended Audience Purpose
Quality assessment of red blood cell concentrates from blood donors at the extremes of the age spectrum: The BEST collaborative study Cloutier M, Cognasse F, Yokoyama APH, Hazegh K, Mykhailova O, Brandon-Coatham M, Hamzeh-Cognasse H, Kutner JM, Acker JP, Kanias T, the Biomedical Excellence for Safer Transfusion Collaborative 2023 Transfusion View Researchers Benchmarking and standard setting
FAQ: Solvent detergent (S/D) treated plasma (Octaplasma) Mack J, Gordon R, Romans R, Webert K, Ning S, Zeller M 2023 Blood.ca website View Health care providers New or improved product or process
Circulaire d'information utilisation de composants sanguins humains: Composants plasmatiques Stewart T 2023 Blood.ca website View Health care providers Benchmarking and standard setting
Loss of Autophagy Activity during Storage of Hematopoietic Stem Cell Grafts Is Associated with Reduced Potency Maganti H, Jahan S, Patel J, Kaushal R, McGregor C, Pasha R, Pineault N 2023 Blood View Researchers Basic research
Rapport d’impact annuel 2022-2023 Innovation et gestion du portefeuille Canadian Blood Services' Innovation & Portfolio Management 2023 Blood.ca website View General public Other
Transfusion thérapeutique de granulocytes Gardner E, Fernandes M, Latour C, Seftel M, Acker J, Clarke G 2023 Guide de la pratique transfusionnelle View Health care providers Benchmarking and standard setting
Effect of Donor Sex on Recipient Mortality in Transfusion Chassé M, Fergusson DA, Tinmouth A, Acker JP, Perelman I, Tuttle A, English SW, Hawken S, Forster AJ, Shehata N, Thavorn K, Wilson K, Cober N, Maddison H, Tokessy M 2023 NEJM View Researchers Clinical research
Monitoring syphilis serology in blood donors: Is there utility as a surrogate marker of early transfusion transmissible infection behavioral risk? O'Brien SF, Drews SJ, Yi Q-L, Osmond L, Tran V, Zhou HY, Goldman M 2023 Transfusion View Researchers Benchmarking and standard setting
What influences decisions to donate plasma? A rapid review of the literature Berger M, Easterbrook A, Holloway K, Devine D, Bansback N 2023 Vox Sang View Researchers Ethical, legal & social implications research
Clinical Outcomes of Umbilical Cord Blood Transplantation Using Ex Vivo Expansion: A Systematic Review and Meta-Analysis of Controlled Studies Saiyin T, Kirkham AM, Bailey AJM, Shorr R, Pineault N, Maganti HB, Allan DS 2023 Transplant Cell Ther View Researchers Clinical research
FAQ: Information for health professionals on apheresis platelet psoralen-treated (APPT) and untreated apheresis platelet in PAS-E Ning S, Nowry A, Zeller M 2023 Blood.ca website View Health care providers Benchmarking and standard setting
Transfusion-transmitted Babesia spp.: a changing landscape of epidemiology, regulation, and risk mitigation Drews SJ, Kjemtrup AM, Krause PJ, Lambert G, Leiby DA, Lewin A, O'Brien SF, Renaud C, Tonnetti L, Bloch EM 2023 J Clin Microbiol View Researchers Benchmarking and standard setting
Auditing a recently implemented massive hemorrhage protocol: feasibility of assessing pre-specified metrics and compliance Leis M, Clarfield L, Lin Y, Gupta A, Da Luz L 2023 CJEM View Health care providers Benchmarking and standard setting
KEL1 negative red cell transfusions for females of current or future child-bearing potential: A clinical impact and feasibility study Ning S, Morin PA, Elahie A, Li N, Liu Y, Barty R, Clarke G, Zeller M, Heddle NM 2023 Transfusion View Health care providers Clinical research
Immunogenicity and safety of mixed COVID-19 vaccine regimens in patients with immune-mediated inflammatory diseases: a single-centre prospective cohort study Hitchon CA, Mesa C, Bernstein CN, Marrie RA, Card C, O’Brien SF, Kim J 2023 BMJ Open View Health care providers Clinical research
Resource for Physicians: Hemolytic disease of the newborn (HDN): IVIG in the management of Rh- and ABO-mediated HDN Lieberman L, La Rocca U, Estcourt L, Jug R, Louw V, Muniz-Diaz E, Maier RF, Christensen R, Goel R, Sheharyar R, Delaney M, Bercovitz R, Bake J, Ramsey G, Pessoa dos Santos M, Charge S, Wolfe A, Bathla A, On behalf of the International Collaboration for Transfusion Medicine Guidelines (ICTMG) 2023 ICTMG.org View Health care providers Benchmarking and standard setting
Genetically engineered transfusable platelets using mRNA lipid nanoparticles Leung J, Strong C, Badior KE, Robertson M, Wu X, Meledeo MA, Kang E, Paul M, Sato Y, Harashima H, Cap AP, Devine DV, Jan E, Cullis PR, Kastrup CJ 2023 Sci Adv View Researchers New or improved product or process
An unsupervised learning approach to identify immunoglobulin utilization patterns using electronic health records Riazi K, Ly M, Barty R, Callum J, Arnold DM, Heddle NM, Down DG, Sidhu D, Li N 2023 Transfusion View Researchers Benchmarking and standard setting
Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis Almizraq RJ, Frias Boligan K, Lewis BJB, Cen S, Whetstone H, Spirig R, Käsermann F, Campbell IK, von Gunten S, Branch DR 2023 Pharmacology View Researchers Basic research
Small Molecule Drugs That Inhibit Phagocytosis Loriamini M, Lewis-Bakker MM, Frias Boligan K, Wang S, Holton MB, Kotra LP, Branch DR 2023 Molecules View Researchers Basic research
Heterodimeric Protein Surface-Coupling Platform: Immobilization of Conformation Switchable and Functional αIIbβ3 Integrin Neves MAD, Slavkovic S, Wang Y, Pasman Y, Shoara AA, Gallant RC, Zhu G, Benvenuto P, Johnson PE, Thompson M, Ni H 2023 Adv Mater Interfaces View Researchers Basic research
Mythbusters: Small Volume Blood Collection Tubes Siegal D, Callum J, Sztainert T 2023 Blood.ca website View Health care providers Benchmarking and standard setting
Intraoperative Blood Management Strategies for Patients Undergoing Noncardiac Surgery: The Ottawa Intraoperative Transfusion Consensus Lenet T, McIsaac DI, Hallet JH, Jerath A, Lalu MM, Nicholls SG, Presseau J, Tinmouth A, Verret M, Wherrett CG, Fergusson DA, Martel G 2023 JAMA Netw Open View Researchers Clinical research
Comparison of automated solid phase versus manual saline indirect antiglobulin test methodology for non-ABO antibody titration: Implications for perinatal antibody monitoring Niu S, Vetsch M, Beaudin L, Bodnar M, Clarke G 2023 Transfusion View Researchers Clinical research
Nutrient supplementation of culture media improves the detection of Cutibacterium acnes in platelet components by an automated culture system Kumaran D, Ramirez-Arcos S 2023 Vox Sang View Researchers Basic research
Cardiovascular events among recipients of hematopoietic stem cell transplantation-A systematic review and meta-analysis Aghel N, Lui M, Wang V, Khalaf D, Mian H, Hillis C, Walker I, Leber B, Lipton JH, Aljama M, Lepic K, Berg T, Garcia-Horton A, Petropoulos J, Masoom H, Leong DP 2023 Bone Marrow Transplant View Researchers Clinical research
Dual roles of fucoidan-GPIbα interaction in thrombosis and hemostasis: implications for drug development targeting GPIbα Shen C, Mackeigan DT, Shoara AA, Xu R, Bhoria P, Karakas D, Ma W, Cerenzia E, Chen Z, Hoard B, Lin L, Lei X, Zhu G, Chen P, Johnson PE, Ni H 2023 J Thromb Haemost View Researchers Basic research
The evolution of SARS-CoV-2 seroprevalence in Canada: a time-series study, 2020–2023 Murphy TJ, Swail H, Jain J, Anderson M, Awadalla P, Behl L, Brown PE, Charlton CL, Colwill K, Drews SJ, Gingras A-C, Hinshaw D, Jha P, Kanji JN, Kirsh VA, Lang ALS, Langlois M-A, Lee S, Lewin A, O’Brien SF, Pambrun C, Skead K, Stephens DA, Stein DR, Tipples G, Caeseele PGV, Evans TG, Oxlade O, Mazer BD, Buckeridge DL 2023 CMAJ View Researchers Clinical research
Management of Pregnancies Alloimmunized with Non-Rh and Non-K Alloantibodies Jackson ME, Grabowska K, Lieberman L, Clarke G, Yan MTS, Canadian Obstetric Pediatric Transfusion Network 2023 J Obstet Gynaecol Can View Health care providers Clinical research
Assessment of the soluble proteins HMGB1, CD40L and CD62P during various platelet preparation processes and the storage of platelet concentrates: The BEST collaborative study Cognasse F, Hamzeh Cognasse H, Eyraud MA, Prier A, Arthaud CA, Tiberghien P, Begue S, de Korte D, Gouwerok E, Greinacher A, Aurich K, Noorman F, Dumont L, Kelly K, Cloutier M, Bazin R, Cardigan R, Huish S, Smethurst P, Devine D, Schubert P, Johnson L, Marks DC, Biomedical Excellence for Safer Transfusion Collaborative 2023 Transfusion View Researchers Basic research
Chapter 2. Blood components Gupta A, Bigham M 2023 Clinical Guide to Transfusion View Health care providers Benchmarking and standard setting
The transfusion-associated dyspnea prospective observation and laboratory assessment study: a protocol for investigating and disambiguating cardiopulmonary and high-grade febrile transfusion reactions in adults McVey M, Saeed S, Siddiqui R, Armali C, Kron A, Branch D, Brinc D, Zhang L, Shehata N, Pavenski K, Gupta A, Lin Y, Lieberman L, Pendergrast J, Callum J, Cserti-Gazdewich C 2023 Int J Clin Trials View Health care providers Clinical research
Sommaire des réactions transfusionnelles indésirables 2018-2023 Yan M 2023 Blood.ca website View Blood operators Benchmarking and standard setting
Hämolytische Erkrankung des Neugeborenen (Morbus haemolyticus neonatorum; MHN) durch Rhesus (Rh)-Antikörper und andere Nicht-ABO-Antikörper International Collaboration for Transfusion Medicine Guidelines 2023 ICTMG.org View General public Other
Using analytical methods and simulation to estimate the magnitude of errors in calculations for recovery in washed red blood cells Blake JT, Acker JP, Mastronardi C 2023 Proceedings of the 13th International Conference on Simulation and Modeling Methodologies, Technologies, and Application View Researchers Basic research
Risk factors for T-cell lymphopenia in frequent platelet donors: The BEST collaborative study Kaufman RM, Marks DC, Flamand Y, Acker JP, Brown BL, Olafson C, Marschner S, Pandey S, Papari M, Petraszko T, Serrano K, Ward D, Bazin R, for the Biomedical Excellence for Safer Transfusion Collaborative 2023 Transfusion View Researchers Clinical research
Systematic review and meta-analysis of randomized controlled trials of mesenchymal stromal cells to treat coronavirus disease 2019: is it too late? Kirkham AM, Bailey AJM, Shorr R, Lalu MM, Fergusson DA, Allan DS 2023 Cytotherapy View Researchers Clinical research
Development and internal validation of a clinical prediction model for the diagnosis of immune thrombocytopenia: reply Mahamad S, Li N, Arnold DM 2023 J Thromb Haemost View Researchers Clinical research
White paper on pandemic preparedness in the blood supply Strengers P, O'Brien SF, Politis C, Mayr W, Seifried E, Spencer BR 2023 Vox Sang View Blood operators Benchmarking and standard setting
TEMRA: the CD8 subset in chronic ITP? Lazarus AH, Semple JW 2023 Blood View Researchers Basic research
Rapport de surveillance O'Brien S 2023 Blood.ca website View Blood operators Benchmarking and standard setting
Doença hemolítica do recém-nascido (DHRN): doença por Rhesus (Rh) e outros anticorpos não-ABO International Collaboration for Transfusion Medicine Guidelines 2023 ICTMG.org View General public Other
Multinational comparison study of aircraft pilot healthcare avoidance behaviour Hoffman WR, Patel PK, Aden J, Willis A, Acker JP, Bjerke E, Miranda E, Luster J, Tvaryanas A 2023 Occup Med (Lond) View Researchers Clinical research
Navigating imperfect policies to donate plasma: Survey on plasma donation and a pilot plasma donation program among men who have sex with men in Canada Vesnaver E, Gibson E, Goldman M, Butler-Foster T, Hill NE, Lapierre D, MacDonagh R, Rubini KA, Miguel G, Rosser A, MacPherson P, Palumbo A, Randall T, Osbourne-Sorrell W, O'Brien SF, Otis J, Greaves M, Al-Bakri TB, Reid M, Labrecque M, Germain M, Orvis S, Clapperton AT, Devine D, Presseau J 2023 Transfusion View Researchers MSM research
Climate change and parasitic risk to the blood supply Drews SJ, Wendel S, Leiby DA, Tonnetti L, Ushiro-Lumb I, O'Brien SF, Lieshout-Krikke RW, Bloch EM, the International Society of Blood Transfusion Working Party Parasite Subgroup 2023 Transfusion View Blood operators Clinical research
FAQ: Information for health professionals ordering granulocyte concentrates Stepien J, Robert M-H 2023 Blood.ca website View Health care providers New or improved product or process
Cold-stored platelets for acute bleeding in cardiac surgical patients: a narrative review Lu J, Karkouti K, Peer M, Englesakis M, Spinella PC, Apelseth TO, Scorer TG, Kahr WHA, McVey M, Rao V, Abrahamyan L, Lieberman L, Mewhort H, Devine DV, Callum J, Bartoszko J 2023 Can J Anaesth View Researchers Clinical research
Mechanism of Small Molecule Inhibitors of Phagocytosis Loriamini M, Lewis-Bakker M, Binnington B, Kotra L, Branch D 2023 J Hematol Clin Res View Researchers Basic research
Immunological impact of the CD71+ RBCs: A potential immune mediator in transfusion Li W, Acker JP 2023 Transfus Apher Sci View Researchers Basic research
Comparison of three dosing intervals for the primary vaccination of the SARS-CoV-2 mRNA Vaccine (BNT162b2) on magnitude, neutralization capacity and durability of the humoral immune response in health care workers: A prospective cohort study Leong DP, Zhang A, Breznik JA, Clare R, Huynh A, Mushtaha M, Rangarajan S, Stacey H, Kim PY, Loeb M, Denburg JA, Mertz D, Chagla Z, Nazy I, Miller MS, Bowdish DME, Duong M 2023 PLoS One View Researchers Clinical research