Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Blood donor characteristics on transfusion outcomes-should obesity be assessed in future clinical trials?-reply Chasse M, Fergusson DA 2017 JAMA Intern Med View Researchers Clinical research
Chapter 5 - Platelet microRNAs Provost P 2013 Platelets (Third Edition) View Researchers Other
Compatibility of Lactated Ringer's Solution human blood products containing red blood cells: a systematic review protocol Wolfe D, English S, Fergusson D, Kanji S, Lalu M, Mendis N, Tinmouth A, McIntyre L 2016 OHRI Publications View Researchers Clinical research
Effect on gene expression of three allelic variants in GATA motifs of ABO, RHD, and RHCE regulatory elements Fennell K, Hoffman R, Yoshida K, Iwamoto S, Govender L, Vather K, Sookraj A, Jentsch U, Pambrun C, McAuley C, Keller M, Ochoa-Garay G 2017 Transfusion View Researchers Basic research
Fanconi anemia proteins interact with CtBP1 and modulate the expression of the Wnt antagonist Dickkopf-1 Huard CC, Tremblay CS, Helsper K, Delisle MC, Schindler D, Levesque G, Carreau M 2013 Blood View Researchers Basic research
Glucagon-like peptide 1 receptor activation attenuates platelet aggregation and thrombosis Cameron-Vendrig A, Reheman A, Siraj MA, Xu XR, Wang Y, Lei X, Afroze T, Shikatani E, El-Mounayri O, Noyan H, Weissleder R, Ni H, Husain M 2016 Diabetes View Researchers Basic research
Hydroxyethyl starch supplemented with ice recrystallization inhibitors greatly improves cryopreservation of human red blood cells Poisson J, Briard J, Turner TR, Acker J, Ben R 2017 BioProcessing Journal View Researchers Basic research
Intravenous immunoglobulin prevents murine antibody-mediated acute lung injury at the level of neutrophil reactive oxygen species (ROS) production Semple JW, Kim M, Hou J, McVey M, Lee YJ, Tabuchi A, Kuebler WM, Chai ZW, Lazarus AH 2012 PLoS One View Researchers Basic research
Liposomes composed of unsaturated lipids for membrane modification of human erythrocytes Stoll C, Holovati JL, Acker JP, Wolkers WF 2011 Mol Membr Biol View Researchers Basic research
Microfluidic approach to genotyping human platelet antigens Lim C, Manage DP, Atrazhev A, Denomme G, Backhouse CJ, Acker JP 2012 IET Nanobiotechnol View Researchers New or improved product or process
Plant food delphinidin-3-glucoside significantly inhibits platelet activation and thrombosis: novel protective roles against cardiovascular diseases Yang Y, Shi Z, Reheman A, Jin JW, Li C, Wang Y, Andrews MC, Chen P, Zhu G, Ling W, Ni H 2012 PLoS One View Researchers Basic research
Polymer brush-based approaches for the development of infection-resistant surfaces Hadjesfandiari N, Yu K, Mei Y, Kizhakkedathu JN 2014 J Mater Chem B Mater Biol Med View Researchers Basic research
Proteome changes in platelets after pathogen inactivation - an interlaboratory consensus Prudent M, D'Alessandro A, Cazenave JP, Devine DV, Gachet C, Greinacher A, Lion N, Schubert P, Steil L, Thiele T, Tissot J-D, Volker U, Zolla L 2014 Transfus Med Rev View Researchers Basic research
Red blood cell transfusion in patients with traumatic brain injury: a systematic review protocol Boutin A, Chasse M, Shemilt M, Lauzier F, Moore L, Zarychanski R, Lacroix J, Fergusson DA, Desjardins P, Turgeon AF 2014 Syst Rev View Researchers Other
Revealing the diversity of extracellular vesicles using high-dimensional flow cytometry analyses Marcoux G, Duchez A-C, Cloutier N, Provost P, Nigrovic PA, Boilard E 2016 Sci Rep View Researchers Basic research
The Platelet as a physiological objection in the circulation Marshall AH, Wang Y, Reheman A, Chen P, Zhu G, Ni H 2014 Pathobiology of human disease: a dynamic encyclopedia of disease mechanisms View Researchers Basic research
Two novel ABCG2 alleles resulting in a Jr (a-) phenotype Berardi P, Cote J, Vege S, Aeschlimann J, Cserti-Gazdewich C, Westhoff CM 2017 Transfusion View Researchers Basic research
MicroRNA-218-5p Promotes Endovascular Trophoblast Differentiation and Spiral Artery Remodeling Brki J, Dunk C, O'Brien J, Fu G, Nadeem L, Wang Y-l, Rosman D, Salem M, Shynlova O, Yougbare I, Ni H, Lye SJ, Peng C 2018 Mol Ther View Researchers Basic research
Rivaroxaban and dabigatran did not affect clotting profiles in plasma reconstituted with varying levels of autologous platelets to the same degree as heparin when evaluated using thromboelastography Gantioqui J, Stevic I, Atkinson H, Chan AKC 2018 Blood Coagul Fibrinolysis View Researchers Basic research
Systematic reviews do not adequately report or address missing outcome data in their analyses: a methodological survey Kahale LA, Diab B, Brignardello-Petersen R, Agarwal A, Mustafa RA, Kwong J, Neumann I, Li L, Lopes LC, Briel M, Busse JW, Iorio A, Vandvik PO, Alexander PE, Guyatt G, Akl EA 2018 J Clin Epidemiol View Researchers Other
Complications of a severe autoimmune hemolytic anemia crisis: transfusional iron overload and gangrenous cholecystitis Menchetti I, Lin Y, Cserti-Gazdewich C, Goldstein J, Law C, Lazarus A, Callum JL 2018 Transfusion View Researchers Clinical research
The epidemiology of multicomponent blood transfusion: a systematic review Perelman I, Khair S, Dermer E, Tinmouth A, Saidenberg E, Fergusson D 2019 Transfus Med View Researchers Clinical research
Donneurs de sang total avec anticorps Yan M 2019 Blood.ca website View Researchers Basic research
Prothrombin, alone or in complex concentrates or plasma, reduces bleeding in a mouse model of blood exchange-induced coagulopathy Eltringham-Smith LJ, Yu R, Qadri SM, Wang Y, Bhakta V, Pryzdial EL, Crosby JR, Ni H, Sheffield WP 2019 Sci Rep View Researchers Basic research
Timeline of heparin-induced thrombocytopenia seroconversion in serial plasma samples tested using an automated latex immunoturbidimetric assay Warkentin TE, Sheppard J-AI, Smith JW, Arnold DM, Nazy I 2019 Int J Lab Hematol View Researchers New or improved product or process
Cluster-randomized trials in transfusion medicine Sirotich E, Barty R, Li N, Arnold DM 2020 Transfusion View Researchers Clinical research
Development of an Ordinal Scale Treatment Endpoint for Adults Hospitalized With Influenza Lee N, Smith SW, Hui DSC, Ye M, Zelyas N, Chan PKS, Drews SJ, Zapernick L, Wong R, Labib M, Shokoples S, Eurich DT 2020 Clin Infect Dis View Researchers Clinical research
The efficacy of ice recrystallization inhibitors in rat lung cryopreservation using a low cost technique for ex vivo subnormothermic lung perfusion Lautner L, Himmat S, Acker JP, Nagendran J 2020 Cryobiology View Researchers Basic research
Illustrated State-of-the-Art Capsules of the ISTH 2020 Congress Ariens R, Becattini C, Bender M, Bergmeier W, Castoldi E, Devreese K, Ellis M, Gailani D, Ignjatovic V, James PD, Kerrigan S, Lambert M, Lee LH, Levi M, Maugeri N, Meijers J, Melero-Martin J, Michelson AD, Mingozzi F, Neeves K, Ni H, Olsson A-K, Prohászka Z, Ranson M, Riva N, Senis Y, van Ommen CH, Vaughan DE, Weisel J 2020 J Thromb Haemost View Researchers Basic research
New insights into IVIg mechanisms and alternatives in autoimmune and inflammatory diseases Norris PAA, Kaur G, Lazarus AH 2020 Curr Opin Hematol View Researchers Basic research
The timing of gamma irradiation and its effect on cell-free and microvesicle-bound hemoglobin. The BEST collaborative study William N, Bicahlo B, Hansen A, de Korte D, Acker JP, Biomedical Excellence for Safer Transfusion Collaborative 2022 Transfusion View Researchers Basic research
Necrotizing enterocolitis and mortality after transfusion of ABO non-identical blood Parvizian MK, Barty R, Heddle NM, Li N, McDougall T, Mukerji A, Fusch C, Solh Z 2021 Transfusion View Researchers Clinical research
Mechanism of increased efficacy of recombinant Fc-?TP-L309C compared to IVIg to ameliorate mouse immune thrombocytopenia Lewis BJB, Binnington B, Blacquiere M, Spirig R, Käsermann F, Branch DR 2021 eJHaem View Researchers Basic research
The SSC platelet immunology register of VITT and VIITP: Toward standardization of laboratory and clinical parameters Choi PY, Grace RF, Therese Ahlen M, Nazy I, Sachs UJ, Arnold DM, McKenzie SE, Althaus K, Sharma R, Bakchoul T 2021 J Thromb Haemost View Researchers Benchmarking and standard setting
Determining the Optimal SARS-CoV-2 mRNA Vaccine Dosing Interval for Maximum Immunogenicity Asamoah-Boaheng M, Goldfarb D, Prusinkiewicz MA, Golding L, Karim ME, Barakauskas V, Wall N, Jassem AN, Marquez AC, MacDonald C, O'Brien SF, Lavoie P, Grunau B 2023 Cureus View Researchers Clinical research
Staphylococcal Enterotoxins Enhance Biofilm Formation by Staphylococcus aureus in Platelet Concentrates Chi SI, Ramirez-Arcos S 2023 Microorganisms View Researchers Basic research
‘A Most Equitable Drug’: How the Clinical Studies of Convalescent Plasma as a Treatment for SARS-CoV-2 Might Usefully Inform Post-Pandemic Public Sector Approaches to Drug Development Grundy Q, Campbell C, Ali R, Herder M, Holloway K 2023 J Law Med Ethics View Researchers Ethical, legal & social implications research
Clinical and laboratory predictors of fetal and neonatal alloimmune thrombocytopenia Matusiak K, Patriquin CJ, Deniz S, Dzaja N, Smith JW, Wang G, Nazy I, Kelton JG, Arnold DM 2022 Transfusion View Researchers Clinical research
Severe fetal anemia caused by anti-Jra: Burst forming unit-erythroid colony formation inhibition assay suggesting possible erythroid suppression mechanism Tran A, Yan MTS, Branch DR, Blacquiere M, Pineault N, Pasha R, Clarke G 2023 Transfusion View Researchers Clinical research
A highly purified form of staphylococcal protein A alleviates murine immune thrombocytopenia (ITP) Kapur R, Catalina MD, Aslam R, Speck ER, Francovitch RF, Semple JW 2017 Br J Haematol View Researchers Basic research
Accelerated apoptotic death and in vivo turnover of erythrocytes in mice lacking functional mitogen- and stress-activated kinase MSK1/2 Lang E, Bissinger R, Fajol A, Salker MS, Singh Y, Zelenak C, Ghashghaeinia M, Gu S, Jilani K, Lupescu A, Reyskens KM, Ackermann TF, Foller M, Schleicher E, Sheffield WP, Arthur JS, Lang F, Qadri SM 2015 Sci Rep View Researchers Basic research
Cancer and platelet crosstalk: opportunities and challenges for aspirin and other anti-platelet agents Xu XR, Yousef GM, Ni H 2018 Blood View Researchers Basic research
Concentré de recherche: Vers une uniformisation des politiques d'exclusion du don de sang et de plasma Goldman M, O'Brien S, Devine D 2018 Blood.ca website View Researchers Basic research
Fibronectin orchestrates thrombosis and hemostasis Wang Y, Carrim N, Ni H 2015 Oncotarget View Researchers Other
Immunoablation and autologous haemopoietic stem-cell transplantation for aggressive multiple sclerosis: a multicentre single-group phase 2 trial Atkins HL, Bowman M, Allan D, Anstee G, Arnold DL, Bar-Or A, Bence-Bruckler I, Birch P, Bredeson C, Chen J, Fergusson D, Halpenny M, Hamelin L, Huebsch L, Hutton B, Laneuville P, Lapierre Y, Lee H, Martin L, McDiarmid S, O'Connor P, Ramsay T, Sabloff M, Walker L, Freedman MS 2016 Lancet View Researchers Clinical research
Pathogen inactivation treatment of plasma and platelet concentrates and their predicted functionality in massive transfusion protocols Arbaeen AF, Schubert P, Serrano K, Carter CJ, Culibrk B, Devine DV 2017 Transfusion View Researchers Basic research
Platelet immunobiology: platelets as prey and predator Kapur R, Semple JW 2018 ISBT Sci Ser View Researchers Basic research
Quality of Red Blood Cells Isolated from Umbilical Cord Blood Stored at Room Temperature Zhurova M, Akabutu J, Acker J 2012 J Blood Transfus View Researchers New or improved product or process
Relaxin receptor antagonist AT-001 synergizes with docetaxel in androgen-independent prostate xenografts Neschadim A, Pritzker LB, Pritzker KP, Branch DR, Summerlee AJ, Trachtenberg J, Silvertown JD 2014 Endocr Relat Cancer View Researchers Basic research
Risk of acute kidney injury in patients randomized to a restrictive versus liberal approach to red blood cell transfusion in cardiac surgery: a substudy protocol of the transfusion requirements in cardiac surgery III noninferiority trial Garg AX, Shehata N, McGuinness S, Whitlock R, Fergusson D, Wald R, Parikh C, Bagshaw SM, Khanykin B, Gregory A, Syed S, Hare GMT, Cuerden MS, Thorpe KE, Hall J, Verma S, Roshanov PS, Sontrop JM, Mazer CD 2018 Can J Kidney Health Dis View Researchers Clinical research