Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Loss of repeat convalescent plasma donors due to waning anti-SARS-CoV-2 plaque reduction neutralization test titers (April-December 2020) Drews S, Devine D, McManus J, Mendoza E, Manguiat K, Girardin R, Dupuis A, McDonough K, Lin J, Evans D, Pambrun C, Drebot M, Wood H 2022 Transfus Med Rev View Blood operators New or improved product or process
Plaquettes extraites de la couche leucoplaquettaire à teneur réduite en agents pathogènes Blais-Normandin I, Tordon B, Anani W 2022 Blood.ca website View Health care providers Benchmarking and standard setting
Methods to Evaluate the Potential Clinical Significance of Antibodies to Red Blood Cells Boligan KF, Sandhu G, Branch DR 2022 Curr Protoc View Researchers Benchmarking and standard setting
Management of immune‐mediated thrombocytopenia Gabe C, Arnold D, Smith J, T W 2022 Rossi's Principles of Transfusion Medicine View Health care providers Benchmarking and standard setting
Why We Swab: A library of stories in stem cell donation Jagelaviciute G, Kum E, Li EW, Rosenfeld A, Williams K, Kandel R, DeGurse N, Park B, Okonofua S, Sano L, Gerofsky M, Sharp A, Hatkar R, Thyagu S, Fingrut WB 2022 Transfusion View Health care providers Ethical, legal & social implications research
Utilization of the Abbott SARS-CoV-2 IgG II Quant Assay To Identify High-Titer Anti-SARS-CoV-2 Neutralizing Plasma against Wild-Type and Variant SARS-CoV-2 Viruses Lin Y-CJ, Evans DH, Robbins NF, Orjuela G, Hu Q, Samson R, Abe KT, Rathod B, Colwill K, Gingras A-C, Tuite A, Yi Q-L, O’Brien SF, Drews SJ 2022 Microbiol Spectr View Health care providers Benchmarking and standard setting
Les fournisseurs de sang canadiens : un rôle croissant dans la surveillance de la santé publique? O’Brien SF, Drews SJ, Lewin A, Osiowy C, Drebot MA, Renaud C 2022 Relevé des maladies transmissibles au Canada View Health care providers New or improved product or process
A mixed methods investigation of the relationship between blood donor policy, interest in donation, and willingness to donate among gay, bisexual, and other men who have sex with men in Ontario, Canada Armstrong JP, Brennan DJ, Collict D, Kesler M, Bekele T, Souleymanov R, Grace D, Lachowsky NJ, Hart TA, Adam BD 2022 BMC Public Health View Researchers MSM research
Staff perspectives on barriers and enablers to implementing alternative source plasma eligibility criteria for gay, bisexual, and other men who have sex with men Castillo G, Vesnaver E, Gibson E, Butler-Foster T, Goldman M, Hill NE, Rosser A, Lapierre D, Rubini KA, MacDonagh R, Miguel G, Palumbo A, MacPherson P, Randall T, Osbourne-Sorrell W, O'Brien SF, Bridel W, Otis J, Greaves M, Al-Bakri TB, Reid M, Labrecque M, Germain M, Orvis S, Clapperton AT, Devine D, Presseau J 2022 Transfusion View Blood operators MSM research
A Prospective Observational Cohort Comparison of SARS-CoV-2 Seroprevalence Between Paramedics and Matched Blood Donors in Canada During the COVID-19 Pandemic Grunau B, O’Brien SF, Kirkham TL, Helmer J, Demers PA, Asamoah-Boaheng M, Drews SJ, Karim ME, Srigley JA, Sediqi S, O’Neill D, Drennan IR, Goldfarb DM 2022 Ann Emerg Med View Researchers Clinical research
Déclaration du CCN concernant le génotypage du RHD chez les patientes enceintes Pavenski K, Khandelwal A, Clarke G, Lane D 2022 National Advisory Committee on Blood and Blood Products View Health care providers Benchmarking and standard setting
Evaluation of riboflavin and ultraviolet light treatment against Klebsiella pneumoniae in whole blood-derived platelets: A pilot study Alabdullatif M, Osman IE, Alrasheed M, Ramirez-Arcos S, Alyousef M, Althawadi S, Alhumiadan H 2021 Transfusion View Researchers New or improved product or process
A trend of dropping anti-SARS-CoV-2 plaque reduction neutralization test titers over time in Canadian convalescent plasma donors Drews SJ, Devine DV, McManus J, Mendoza E, Manguiat K, Wood H, Girardin R, Dupuis A, McDonough K, Drebot M 2021 Transfusion View Researchers Basic research
Recommended primary outcomes for clinical trials evaluating hemostatic blood products and agents in patients with bleeding: Proceedings of a National Heart Lung and Blood Institute and US Department of Defense Consensus Conference Spinella PC, El Kassar N, Cap AP, Kindzelski AL, Almond CS, Barkun A, Gernsheimer TB, Goldstein JN, Holcomb JB, Iorio A, Jensen DM, Key NS, Levy JH, Mayer SA, Moore EE, Stanworth SJ, Lewis RJ, Steiner ME 2021 J Trauma Acute Care Surg View Researchers Benchmarking and standard setting
ResearchUnit: Treating bleeding during cardiac surgery: Is prothrombin complex concentrate a substitute for plasma? Kron A 2021 Blood.ca website View Health care providers Clinical research
The importance of evaluating differences in HES formulations used in hematopoietic progenitor cell cryopreservation Halpenny M, William N, Elmoazzen H, Giulivi A, Martin L, Perron D, Bredeson C, Hamelin L, Huebsch L, Yang L, Birch P, Acker JP 2021 Cytotherapy View Blood operators New or improved product or process
Treatment-induced cerebral sinus venous thrombosis in childhood acute lymphoblastic malignancies: New risk factors to consider El-Khoury H, Saifi O, Haddad S, Chahrour M, Ghanem KM, Mubarak Y, Tamim H, Makki M, Zakka C, Chan AK, Mahfouz R, Tarek N, El-Solh H, Abboud MR, Saab R, Muwakkit SA 2021 Pediatr Blood Cancer View Health care providers Clinical research
Discrete-Event Simulation to Model the Thrombolysis Process for Acute Ischemic Stroke Patients at Urban and Rural Hospitals Bulmer T, Volders D, Blake J, Kamal N 2021 Front Neurol View Researchers New or improved product or process
Extensive variability in platelet, bleeding, and QOL outcome measures in adult and pediatric ITP: Communication from the ISTH SSC subcommittee on platelet immunology Al-Samkari H, Cronin A, Arnold DM, Rodeghiero F, Grace RF 2021 J Thromb Haemost View Health care providers Benchmarking and standard setting
Filariasis and transfusion-associated risk: a literature review Drews SJ, Spencer BR, Wendel S, Bloch EM, International Society of Blood Transfusion TTID Working Party Parasite Subgroup 2021 Vox Sang View Health care providers Clinical research
Stepping Stones or Second Class Donors?: a qualitative analysis of gay, bisexual, and queer men's perspectives on plasma donation policy in Canada Grace D, Gaspar M, Klassen B, Lessard D, Anand P, Brennan DJ, Lachowsky N, Adam BD, Cox J, Lambert G, Jollimore J, Hart TA 2021 BMC Public Health View Blood operators MSM research
Vox Sanguinis International Forum on Mitigation Strategies to Prevent Faint and Pre-faint Adverse Reactions in Whole Blood Donors: Summary Goldman M, Townsend M, Magnussen K, Lozano M, Nissen-Meyer LS, Lee CK, Leung JN, Takanashi M, McKay J, Kvist M, Robitaille N, Deschênes J, Di Angelantonio E, McMahon A, Roberts D, Maghsudlu M, Castrén J, Tiberghien P, Woimant G, Morel P, Kamel H, Bravo M, Shinhar E, Gendelman V, Raz H, Wendel S, Fachini R, Quee F, van den Hurk K, Wiersum J, Grima K, Speedy J, Bruun M, Dunbar N 2021 Vox Sang View Health care providers Benchmarking and standard setting
Effect of cryopreservation on a rare McLeod donor red blood cell concentrate Turner TR, Clarke G, Denomme GA, Skeate R, Acker JP 2021 Immunohematology View Researchers Basic research
A multisite study of pertussis vaccine effectiveness by time since last vaccine dose from three Canadian provinces: A Canadian Immunization Research Network study Savage RD, Bell CA, Righolt CH, Wilkinson K, Schwartz KL, Chen C, Bolotin S, Deeks SL, Drews SJ, Jamieson FB, Johnson C, Kwong JC, Mahmud SM, Russell ML, Simmonds KA, Svenson LW, Crowcroft NS 2021 Vaccine View Researchers Clinical research
ResearchUnit: Convalescent plasma is an ineffective treatment for patients with COVID-19 Modi D 2021 Blood.ca website View Health care providers Clinical research
GPIb? is the driving force of hepatic thrombopoietin generation Karakas D, Xu M, Ni H 2021 Res Pract Thromb Haem View Researchers Basic research
Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia Greinacher A, Selleng K, Palankar R, Wesche J, Handtke S, Wolff M, Aurich K, Lalk M, Methling K, Völker U, Hentschker C, Michalik S, Steil L, Reder A, Schönborn L, Beer M, Franzke K, Büttner A, Fehse B, Stavrou EX, Rangaswamy C, Mailer RK, Englert H, Frye M, Thiele T, Kochanek S, Krutzke L, Siegerist F, Endlich N, Warkentin TE, Renné T 2021 Blood View Researchers Basic research
The Virulence of S. marcescens Strains Isolated From Contaminated Blood Products Is Divergent in the C. elegans Infection Model Diamandas A, Razon MR, Ramirez-Arcos S, Brassinga AKC 2021 Front Genet View Researchers Basic research
Hypothermic storage of leukoreduced red blood cells for greater than 21-days is a safe alternative to irradiation Mykhailova O, Turner TR, Olafson C, Howell A, Nahirniak SN, Wizniak J, Gerges HYN, Baldwin T, Clarke G, Acker JP 2021 Transfusion View Researchers New or improved product or process
Multicenter observational study evaluating the impact of platelet transport bags on product wastage Kron A, Vijenthira S, Pendergrast J, Modi D, McLaren A, MacDonald A, Armali C, Cserti-Gazdewich C, Smith E, Quest G, Gabanowicz K, Lieberman L, Aseltine L, Sani L, Roche M, DeOliviera M, Yu P, Fazari S, Patel S, Lin Y, Kelly Z, Callum J 2021 Transfusion View Researchers New or improved product or process
Magnetic resonance imaging in boys with severe hemophilia A: Serial and end-of-study findings from the Canadian Hemophilia Primary Prophylaxis Study Stimec J, Dover S, Pullenayegum E, Blanchette VS, Doria AS, Feldman BM, Carcao M, Rivard GE, Israels SJ, Chan AK, Steele M, Cloutier S, Klaassen RJ, Price VE, Sinha R, Laferriere N, Paradis E, Wu JKM, Babyn P 2021 Res Pract Thromb Haemost View Researchers Clinical research
Ex vivo hemostatic and immuno-inflammatory profiles of freeze-dried plasma Peng HT, Rhind SG, Devine D, Jenkins C, Beckett A 2021 Transfusion View Researchers Clinical research
Research Unit: A more accurate and efficient way to manage blood demand and supply Li N 2021 Blood.ca website View Health care providers New or improved product or process
Antibody epitopes in vaccine-induced immune thrombotic thrombocytopaenia Huynh A, Kelton JG, Arnold DM, Daka M, Nazy I 2021 Nature View Researchers Clinical research
Effect of unfractionated heparin and low molecular weight heparin on the clotting of platelet-reduced whole blood: an in-vitro study utilizing thromboelastography Chung J, Stevic I, Gantioqui J, Atkinson H, Chan AKC, Chan HHW 2021 Blood Coagul Fibrinolysis View Researchers Clinical research
The association of prothrombin complex concentrates with postoperative outcomes in cardiac surgery: an observational substudy of the FIBRES randomized controlled trial Bartoszko J, Callum J, Karkouti K 2021 Can J Anaesth View Researchers Clinical research
Administration de produits sanguins O'Reilly C 2021 Guide de la pratique transfusionnelle View Health care providers Benchmarking and standard setting
The Monocyte Monolayer Assay to Build a Personalized Pipeline of Transfusion Support in Highly Sensitized Sickle Cell Disease Vijenthira S, Nguyen J, Branch DR, Clarke G, Ward R, Saeed S, Cserti-Gazdewich C 2021 Blood View Health care providers New or improved product or process
Digital Microfluidic Hemagglutination Assays for Blood Typing, Donor Compatibility Testing, and Hematocrit Analysis Sklavounos AA, Lamanna J, Modi D, Gupta S, Mariakakis A, Callum J, Wheeler AR 2021 Clin Chem View Researchers New or improved product or process
The estimated risk of SARS-CoV- 2 infection via cornea transplant in Canada O’Brien SF, Lewin A, Yi Q-L, Dowling G, Fissette E, Drews SJ 2021 Cell Tissue Bank View Health care providers Clinical research
Stuttering priapism in a patient with sickle cell trait treated with automated red cell exchange transfusion Ebraheem MS, Verhovsek M 2021 Blood Adv View Health care providers Clinical research
International Forum on the Collection and Use of COVID-19 Convalescent Plasma: Responses Al-Riyami AZ, Burnouf T, Yazer M, Triulzi D, Kuma? LT, Sa?dur L, Pelit NB, Bazin R, Hindawi SI, Badawi MA, Patidar GK, Pandey HC, Chaurasia R, Fachini RM, Scuracchio P, Wendel S, Ang AL, Ong KH, Young P, Ihalainen J, Vierikko A, Qiu Y, Yang R, Xu H, Rahimi-Levene N, Shinar E, Izak M, Gonzalez CA, Ferrari DM, Cini PV, Aditya RN, Sharma RR, Sachdev S, Hans R, Lamba DS, Nissen-Meyer LSH, Devine DV, Lee CK, Leung JN-S, Hung IFN, Tiberghien P, Gallian P, Morel P, Al Maamari K, Al-Hinai Z, Vrielink H, So-Osman C, De Angelis V, Berti P, Ostuni A, Marano G, Nevessignsky MT, El Ekiaby M, Daly J, Hoad V, Kim S, van den Berg K, Vermeulen M, Glatt TN, Schäfer R, Reik R, Gammon R, Lopez M, Estcourt L, MacLennan S, Roberts D, Louw V, Dunbar N 2021 Vox Sang View Researchers Clinical research
Frequency and timing of all-cause deaths in visits involving suspected transfusion reactions, and the significance of cardiopulmonary disturbances McVey MJ, Cohen R, Arsenault V, Escorcia A, Tasmin F, Pendergrast J, Lieberman L, Lin Y, Callum J, Cserti-Gazdewich C 2021 Vox Sang View Health care providers Clinical research
Stepwise Reversion of Multiply Mutated Recombinant Antitrypsin Reveals a Selective Inhibitor of Coagulation Factor XIa as Active as the M358R Variant Hamada M, Bhakta V, Andres SN, Sheffield WP 2021 Front Cardiovasc Med View Researchers Basic research
International Forum on Walking Blood Bank Programmes: Responses Martinaud C, Scorer T, Lozano M, Miles A, Fitchett G, Ba A, Wikman A, Nimberger-Hansson P, Enbuske S, Bohon?k M, Devine D, Beckett AN, Mbanya D, T'Sas F, Degueldre J, Chueca M, Dedome E, Apelseth T, Strandenes G, Wendel S, Fachini R, Olszewski A, Dupont C, Glassberg E, Shinar E, Taylor AL, Corley JB, Nadarajan VS, Dunbar N 2021 Vox Sang View Blood operators New or improved product or process
Novel Mechanisms of Thrombopoietin Generation: The Essential Role of Kupffer Cells Karakas D, Li J, Ni H 2021 Blood View Researchers Basic research
Anti-platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein Greinacher A, Selleng K, Mayerle J, Palankar R, Wesche J, Reiche S, Aebischer A, Warkentin TE, Muenchhoff M, Hellmuth JC, Keppler OT, Duerschmied D, Lother A, Rieg S, Gawaz MP, Mueller KAL, Scheer CS, Napp M, Hahnenkamp K, Lucchese G, Vogelgesang A, Flöel A, Lovreglio P, Stufano A, Marschalek R, Thiele T 2021 Blood View Researchers Clinical research
Buffy coat platelets coming to America: Are we ready? Gammon RR, Devine D, Katz LM, Quinley E, Wu Y, Rowe K, Razatos A, Min K, Reichenberg S, Smith R 2021 Transfusion View Blood operators New or improved product or process
Efficacy and safety of tranexamic acid in acute traumatic brain injury: a systematic review and meta-analysis of randomized-controlled trials Lawati KA, Sharif S, Maqbali SA, Rimawi HA, Petrosoniak A, Belley-Cote EP, Sharma SV, Morgenstern J, Fernando SM, Owen JJ, Zeller M, Quinlan D, Alhazzani W, Rochwerg B 2021 Intensive Care Med Researchers Clinical research
Identification of an alpha-1 antitrypsin variant with enhanced specificity for factor XIa by phage display, bacterial expression, and combinatorial mutagenesis Bhakta V, Hamada M, Nouanesengsy A, Lapierre J, Perruzza DL, Sheffield WP 2021 Sci Rep View Researchers Basic research