Our Research Publications

Updated August 2025

Title Authors Year Journal Link to Article Intended Audience Purpose
c-Mpl-del, a c-Mpl alternative splicing isoform, promotes AMKL progression and chemoresistance Li F, Xiong Y, Yang M, Chen P, Zhang J, Wang Q, Xu M, Wang Y, He Z, Zhao X, Huang J, Gu X, Zhang L, Sun R, Sun X, Li J, Ou J, Xu T, Huang X, Cao Y, Xu XR, Karakas D, Li J, Ni H, Zhang Q 2022 Cell Death Dis View Researchers Basic research
Switching from standard to extended half-life FVIII prophylaxis in haemophilia A: Comparison of factor product use, bleed rates and pharmacokinetics Nummi V, Lehtinen AE, Iorio A, Szanto T, Lassila R 2022 Haemophilia View Researchers Clinical research
Changing Patterns of SARS-CoV-2 Seroprevalence among Canadian Blood Donors during the Vaccine Era Reedman CN, Drews SJ, Yi Q-L, Pambrun C, O’Brien SF 2022 Microbiol Spectr View Researchers Clinical research
Concentré de recherche: Le risque de transmission du VIH est demeuré inchangé avec l’élargissement des critères d’admissibilité aux hommes gais, bisexuels et autres hommes ayant des rapports sexuels avec d’autres hommes Walsh G 2022 Blood.ca website View Regulators MSM research
Fostamatinib for the treatment of warm antibody autoimmune hemolytic anemia: Phase 2, multicenter, open-label study Kuter DJ, Rogers KA, Boxer MA, Choi M, Agajanian R, Arnold DM, Broome CM, Field JJ, Murakhovskaya I, Numerof R, Tong S 2022 Am J Hematol View Researchers Clinical research
Blood Collection Agency Messaging to Donors and the Public in Canada and Australia During the Early Days of COVID-19 Haw J, Thorpe R, Holloway K 2022 Front Commun View Blood operators Ethical, legal and social implications research
An intron c.149-2632T>A change in RHD is associated with aberrant transcription and very weak D phenotype Floch A, Vege S, Berardi P, Hannon J, Ochoa-Garay G, Lomas-Francis C, Westhoff CM 2022 Transfusion View Researchers Clinical research
International Forum on Policies and Practice for Transfusion of ABO and RhD Non-Identical Platelets: Summary Cardigan R, New HV, Estcourt L, Zhiburt E, Dubey R, Bengtsson J, Jöud M, Castillo C, Cid J, Lozano M, Gounder D, Flanagan P, Morley S, Clarke G, Devine D, Hindawi S, AlOtaibi A, Bub CB, Kutner JM, Ikeda T, Goto N, Okazaki H, Fontaine MJ, Pasion J, Song L, Latham T, Kerkhoffs JL, de Haas M, Zwaginga JJ, Gathof BS, Ommer K, Pirenne F, Raba M, Francois A, Daly J, Powley T, Dunbar N 2022 Vox Sang View Health care providers Benchmarking and standard setting
Donor-recipient sex is associated with transfusion-related outcomes in critically ill patients Alshalani A, Uhel F, Cremer OL, Schultz MJ, de Vooght KMK, van Bruggen R, Acker JP, Juffermans NP 2022 Blood Adv View Researchers Clinical research
Novel platelet products including cold-stored platelets Devine DV 2022 Hematology View Health care providers New or improved product or process
Investigation of Acute Transfusion Reactions Leary H, Webert KE, Heddle NM 2022 Practical Transfusion Medicine View Health care providers Benchmarking and standard setting
Database-driven research and big data analytic approaches in transfusion medicine Ning S, Li N, Barty R, Arnold D, Heddle NM 2022 Transfusion View Researchers Clinical research
A positive blood culture is associated with a lower haemoglobin increment in hospitalized patients after red blood cell transfusion Qadri SM, Liu Y, Barty RL, Heddle NM, Sheffield WP 2022 Vox Sang View Researchers Clinical research
Concentré de recherche: Évaluation de la sécurité des pompes à perfusion pour les transfusions de globules rouges Wolfe A 2022 Blood.ca website View Researchers Benchmarking and standard setting
Vaccine-induced immune thrombotic thrombocytopenia (VITT) - update on diagnosis and management considering different resources: Response to Comment from Yamada et al Greinacher A, Langer F, Makris M, Pai M, Pavord S, Tran H, Warkentin TE 2022 J Thromb Haemost View Health care providers Clinical research
Demand and usage of unrelated donor products for allogeneic haematopoietic cell transplantation during the COVID-19 pandemic: A Canadian Blood Services Stem Cell Registry analysis Allan DS, Green M, Morris G, Weiss J, Dibdin N, Mercer D, Seftel M 2022 Vox Sang View Blood operators Clinical research
Risk factors for bleeding in people living with hemophilia A and B treated with regular prophylaxis: A systematic review of the literature Germini F, Noronha N, Abraham Philip B, Olasupo O, Pete D, Navarro T, Keepanasseril A, Matino D, de Wit K, Parpia S, Iorio A 2022 J Thromb Haemost View Researchers Clinical research
Reaffirmed Guideline No. 343: Routine Non-Invasive Prenatal Prediction of Fetal RHD Genotype Johnson J-A, MacDonald K, Clarke G, Skoll A 2022 J Obstet Gynaecol Can View Health care providers Benchmarking and standard setting
Mortality and its associated factors in transfused patients at a tertiary hospital in Uganda Okello CD, Shih AW, Angucia B, Kiwanuka N, Heddle N, Orem J, Mayanja-Kizza H 2022 PLoS One View Health care providers Clinical research
Circular of information for the use of human blood components: Platelets Stewart T 2022 Blood.ca website View Health care providers Benchmarking and standard setting
Circular of information for the use of human blood components: Platelets Jenkins C 2021 Blood.ca website Health care providers Benchmarking and standard setting
FcgammaRI and FcgammaRIII on splenic macrophages mediate phagocytosis of anti-glycoprotein IIb/IIIa autoantibody-opsonized platelets in immune thrombocytopenia Norris PAA, Segel GB, Burack WR, Sachs UJ, Lissenberg-Thunnissen SN, Vidarsson G, Bayat B, Cserti-Gazdewich CM, Callum J, Lin Y, Branch D, Kapur R, Semple JW, Lazarus AH 2021 Haematologica View Researchers Basic research
Pragmatic, double-blind, randomised trial evaluating the impact of red blood cell donor sex on recipient mortality in an academic hospital population: the innovative Trial Assessing Donor Sex (iTADS) protocol Fergusson DA, Chassé M, Tinmouth A, Acker JP, English S, Forster AJ, Hawken S, Shehata N, Thavorn K, Wilson K, Tuttle A, Perelman I, Cober N, Maddison H, Tokessy M 2021 BMJ Open View Researchers Clinical research
DNA Mediated Blood Coagulation: Extracellular DNA Accelerates Fibrinogen Polymerization By Thrombin Independent of Contact Pathway Vappala S, Straus S, Pryzdial EL, Conway E, Kizhakkedathu J 2021 Blood View Researchers Basic research
Reconstituted cryopreserved platelets synthesize proteins during short-term storage and packaging a defined subset into microvesicles Schubert P, Johnson L, Culibrk B, Chen Z, Tan S, Marks DC, Devine DV 2021 Transfusion View Researchers New or improved product or process
Major clinical trial finds convalescent plasma does not help patients with COVID-19 Modi D 2021 Ontario Regional Blood Coordinating Network December 2021 Newsletter View Health care providers Clinical research
A Higher Antibody Response Is Generated With a 6- to 7-Week (vs Standard) Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Dosing Interval Grunau B, Asamoah-Boaheng M, Lavoie PM, Karim ME, Kirkham TL, Demers PA, Barakauskas V, Marquez AC, Jassem AN, O'Brien SF, Drews SJ, Haig S, Cheskes S, Goldfarb DM 2021 Clin Infect Dis View Researchers Clinical research
Chapter 6: Donor selection, donor testing and pathogen reduction Drews S, Khandelwal A, Goldman M, Devine D 2021 Clinical Guide to Transfusion View Health care providers Benchmarking and standard setting
Estimating the impact on the inventory of implementing pathogen-reduced platelets in Canada Blake JT, McTaggart K, Couture C 2021 Transfusion View Blood operators Benchmarking and standard setting
Necrotizing enterocolitis and mortality after transfusion of ABO non-identical blood Parvizian MK, Barty R, Heddle NM, Li N, McDougall T, Mukerji A, Fusch C, Solh Z 2021 Transfusion View Researchers Clinical research
Mechanism of increased efficacy of recombinant Fc-?TP-L309C compared to IVIg to ameliorate mouse immune thrombocytopenia Lewis BJB, Binnington B, Blacquiere M, Spirig R, Käsermann F, Branch DR 2021 eJHaem View Researchers Basic research
Evidence of SARS-CoV-2 Infection in Cells, Tissues, and Organs and the Risk of Transmission Through Transplantation Gaussen A, Hornby L, Rockl G, O’Brien S, Delage G, Sapir-Pichhadze R, Drews SJ, Weiss MJ, Lewin A 2021 Transplantation View Health care providers Clinical research
The SSC platelet immunology register of VITT and VIITP: Toward standardization of laboratory and clinical parameters Choi PY, Grace RF, Therese Ahlen M, Nazy I, Sachs UJ, Arnold DM, McKenzie SE, Althaus K, Sharma R, Bakchoul T 2021 J Thromb Haemost View Researchers Benchmarking and standard setting
ResearchUnit: Intravenous albumin is not associated with improved outcomes in cardiac surgery patients Bartoszko J 2021 Blood.ca website View Health care providers Clinical research
Compliance with the massive hemorrhage protocol in trauma: a retrospective quality review Khayyat H, Callum JL, Hill-Strathy M, Strauss R, Notario L, Nathens A, da Luz L 2021 Can J Anaesth View Health care providers Clinical research
Registration errors among patients receiving blood transfusions: a national analysis from 2008 to 2017 Vijenthira S, Armali C, Downie H, Wilson A, Paton K, Berry B, Wu HX, Robitaille A, Cserti-Gazdewich C, Callum J 2021 Vox Sang View Health care providers Clinical research
Successful prenatal therapy for anti-CD36-mediated severe FNAIT by deglycosylated antibodies in a novel murine model Xu X, Chen D, Ye X, Xia W, Xu Y, Chen Y, Shao Y, Deng J, Ding H, Liu J, Wang J, Ni H, Fu Y, Santoso S 2021 Blood View Researchers Basic research
Evaluating the Tactical Combat Casualty Care principles in civilian and military settings: systematic review, knowledge gap analysis and recommendations for future research Strauss R, Menchetti I, Perrier L, Blondal E, Peng H, Sullivan-Kwantes W, Tien H, Nathens A, Beckett A, Callum J, da Luz LT 2021 Trauma Surg Acute Care Open View Health care providers Clinical research
Chapitre 15: Composants sanguins négatifs pour les anti-CMV, irradiés et lavéss Prokopchuk-Gauk O, Solh Z 2021 Guide de la pratique transfusionnelle View Health care providers Benchmarking and standard setting
SARS-CoV-2 seroprevalence among Vancouver public school staff in British Columbia, Canada Goldfarb DM, Mâsse LC, Watts AW, Hutchison SM, Muttucomaroe L, Bosman ES, Barakauskas VE, Choi A, Irvine MA, Reicherz F, Coombs D, O’Reilly C, Sediqi S, Razzaghian HR, Sadarangani M, O’Brien SF, Lavoie PM 2021 medRxiv View Researchers Clinical research
Concentré de recherche: Transfusion de plaquettes chez les enfants atteints de cancer Barty R 2021 Blood.ca website View Health care providers Benchmarking and standard setting
Evidence of SARS-CoV-2 Infection in Cells, Tissues and Organs and the Risk of Transmission Through Transplantation Gaussen A, Hornby L, Rockl G, O'Brien S, Delage G, Sapir-Pichhadze R, Drews SJ, Weiss MJ, Lewin A 2021 Transplantation View Health care providers Clinical research
International survey on Helicobacter pylori testing in patients with immune thrombocytopenia: Communication of the platelet immunology scientific and standardization committee Vishnu P, Duncan J, Connell N, Cooper N, Lim W, Rodeghiero F, Tomiyama Y, Grace RF, Bakchoul T, Arnold DM 2021 J Thromb Haemost View Health care providers Benchmarking and standard setting
A Higher Antibody Response Is Generated With a 6- to 7-Week (vs Standard) Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Dosing Interval Grunau B, Asamoah-Boaheng M, Lavoie PM, Karim ME, Kirkham TL, Demers PA, Barakauskas V, Marquez AC, Jassem AN, O’Brien SF, Drews SJ, Haig S, Cheskes S, Goldfarb DM 2021 Clin Infect Dis View Researchers Clinical research
Terminal half-life of FVIII and FIX according to age, blood group and concentrate type: Data from the WAPPS database Versloot O, Iserman E, Chelle P, Germini F, Edginton AN, Schutgens REG, Iorio A, Fischer K 2021 J Thromb Haemost View Researchers Clinical research
Antibody and cellular therapies for treatment of covid-19: a living systematic review and network meta-analysis Siemieniuk RA, Bartoszko JJ, Díaz Martinez JP, Kum E, Qasim A, Zeraatkar D, Izcovich A, Mangala S, Ge L, Han MA, Agoritsas T, Arnold D, Ávila C, Chu DK, Couban R, Cusano E, Darzi AJ, Devji T, Foroutan F, Ghadimi M, Khamis A, Lamontagne F, Loeb M, Miroshnychenko A, Motaghi S, Murthy S, Mustafa RA, Rada G, Rochwerg B, Switzer C, Vandvik PO, Vernooij RW, Wang Y, Yao L, Guyatt GH, Brignardello-Petersen R 2021 BMJ View Researchers Clinical research
Rapport de surveillance 2020 O'Brien S 2021 Blood.ca website View Health care providers Benchmarking and standard setting
Anaphylactic transfusion reactions and IgA deficiency Khandelwal A, Clarke G, Goldman M 2021 Blood.ca website View Health care providers Benchmarking and standard setting
Current Understanding of the Relationship between Blood Donor Variability and Blood Component Quality Hadjesfandiari N, Khorshidfar M, Devine DV 2021 Int J Mol Sci View Blood operators New or improved product or process
COVID-19 convalescent plasma: Interim recommendations from the AABB Cohn CS, Estcourt L, Grossman BJ, Pagano MB, Allen ES, Bloch EM, Casadevall A, Devine DV, Dunbar NM, Foroutan F, Gniadek TJ, Goel R, Gorlin J, Joyner MJ, Metcalf RA, Raval JS, Rice TW, Shaz BH, Vassallo RR, Winters JL, Beaudoin G, Tobian AAR 2021 Transfusion View Health care providers Clinical research