Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
The first case of severe acute hemolytic transfusion reaction caused by anti-Sc2 Lemay A-S, Tong TN, Branch DR, Huang M, Sumner C, Oldfield L, Hawes J, Cserti-Gazdewich CM, Lau W 2018 Transfusion View Researchers Clinical research
Low-molecular-weight heparin venous thromboprophylaxis in critically ill patients with renal dysfunction: A subgroup analysis of the PROTECT trial Pai M, Adhikari NKJ, Ostermann M, Heels-Ansdell D, Douketis JD, Skrobik Y, Qushmaq I, Meade M, Guyatt G, Geerts W, Walsh MW, Crowther MA, Friedrich JO, Burry L, Bellomo R, Brandao da Silva N, Costa Filho R, Cox MJ, Alves Silva S, Cook DJ, on behalf of the PROTECT Investigators 2018 PLoS One View Researchers Clinical research
Ultraviolet-based pathogen inactivation systems: untangling the molecular targets activated in platelets Schubert P, Johnson L, Marks DC, Devine DV 2018 Front Med View Researchers Basic research
Intravenous immunoglobulin (IVIg) or IVIg-treated macrophages reduce DSS-induced colitis by inducing macrophage IL-10 production Kozicky LK, Menzies SC, Hotte N, Madsen KL, Sly LM 2019 Eur J Immunol View Researchers Basic research
Platelet rich plasma in treatment of musculoskeletal pathologies Mehrabani D, Seghatchian J, Acker JP 2019 Transfus Apher Sci View Researchers Basic research
Aging, chronic inflammation, and platelet hyperactivity Ma W, Karakas D, Chen ZY, Ni H 2020 Ann Blood View Researchers Basic research
A crosswalk tabular review on methods and outcomes from randomized clinical trials using pathogen reduced platelets Rebulla P, Garban F, van der Meer PF, Heddle NM, McCullough J 2020 Transfusion View Researchers Clinical research
Update on newer approaches to prevent or treat COVID-19 infection: What we all need the most right now!! Seghatchian J, Acker JP, Putter JS 2020 Transfus Apher Sci View Researchers New or improved product or process
Terminal half-life of FVIII and FIX according to age, blood group and concentrate type: Data from the WAPPS database Versloot O, Iserman E, Chelle P, Germini F, Edginton AN, Schutgens REG, Iorio A, Fischer K 2021 J Thromb Haemost View Researchers Clinical research
Antibody and cellular therapies for treatment of covid-19: a living systematic review and network meta-analysis Siemieniuk RA, Bartoszko JJ, Díaz Martinez JP, Kum E, Qasim A, Zeraatkar D, Izcovich A, Mangala S, Ge L, Han MA, Agoritsas T, Arnold D, Ávila C, Chu DK, Couban R, Cusano E, Darzi AJ, Devji T, Foroutan F, Ghadimi M, Khamis A, Lamontagne F, Loeb M, Miroshnychenko A, Motaghi S, Murthy S, Mustafa RA, Rada G, Rochwerg B, Switzer C, Vandvik PO, Vernooij RW, Wang Y, Yao L, Guyatt GH, Brignardello-Petersen R 2021 BMJ View Researchers Clinical research
Hemolysis after high-dose intravenous immunoglobulin: An under-appreciated sequelae Branch DR, Almizraq RJ, Bussel JB 2022 Am J Hematol View Researchers Basic research
Prolonged Blood Storage and Risk of Posttransfusion Acute Kidney Injury Adegboye J, Sapatnekar S, Mascha EJ, Shah K, Lioudis M, Essber H, Cohen B, Rivas E, Heddle NM, Eikelboom JW, Ellis MH, Sharon Y, Sinha R, Kurz A, Sessler DI 2022 Anesthesiology View Researchers Clinical research
A critical contribution in a time of crisis: Examining motivations and deterrents to COVID-19 convalescent plasma donation and future donation intentions among prospective Canadian donors Holloway K, Campbell C, Ali R, Huyer LD, Hart D, Haw J, Brennenstuhl S, Grundy Q 2022 Transfus Med View Researchers Ethical, legal & social implications research
Hypoxia and low temperature upregulate transferrin to induce hypercoagulability at high altitude Li M, Tang X, Liao Z, Shen C, Cheng R, Fang M, Wang G, Li Y, Tang S, Xie L, Zhang Z, Kamau PM, Mwangi J, Lu Q, Li Y, Wang Y, MacKeigan DT, Cerenzia EG, Ni H, Lai R 2022 Blood View Researchers Basic research
RE: A better normal in Canada will need a better detection system for emerging and re-emerging respiratory pathogens O'Brien S, Goldman M, Drews S 2022 CMAJ View Researchers Clinical research
Clinical Outcomes of Umbilical Cord Blood Transplantation Using Ex Vivo Expansion: A Systematic Review and Meta-Analysis of Controlled Studies Saiyin T, Kirkham AM, Bailey AJM, Shorr R, Pineault N, Maganti HB, Allan DS 2023 Transplant Cell Ther View Researchers Clinical research
Contamination of platelet concentrates with Staphylococcus aureus induces significant modulations in platelet functionality Yousuf B, Pasha R, Pineault N, Ramirez-Arcos S 2022 Vox Sang View Researchers Basic research
A novel VSV/HIV pseudotype approach for the study of HIV microbicides without requirement for level 3 biocontainment Harrison AL, Henry S, Mahfoud R, Manis A, Albertini A, Gaudin Y, Lingwood CA, Branch DR 2011 Future Virol View Researchers Basic research
Cell-based therapy using umbilical cord blood for novel indications in regenerative therapy and immune modulation: an updated systematic scoping review of the literature Rizk M, Aziz J, Shorr R, Allan DS 2017 Biol Blood Marrow Transplant View Researchers Clinical research
Complement C1q enhances homing-related responses of hematopoietic stem/progenitor cells Jalili A, Marquez-Curtis L, Shirvaikar N, Wysoczynski M, Ratajczak M, Janowska-Wieczorek A 2010 Transfusion View Researchers Basic research
Dengue virus binding and replication by platelets Simon AY, Sutherland MR, Pryzdial ELG 2015 Blood View Researchers Basic research
Distribution, origin and contamination risk of coagulase-negative staphylococci from platelet concentrates Rood IGH, de Korte D, Ramírez-Arcos S, Savelkoul PHM, Pettersson A 2011 J Med Microbiol View Researchers Basic research
Effectiveness and safety of thiotepa as conditioning treatment prior to stem cell transplant in patients with central nervous system lymphoma Kokolo MB, Fergusson D, O'Neill J, Tay J, Tinmouth AT, Stewart D, Bredeson C 2014 Leuk Lymphoma View Researchers Clinical research
Evaluating mesenchymal stem cell therapy for sepsis with preclinical meta-analyses prior to initiating a first-in-human trial Lalu MM, Sullivan KJ, Mei SHJ, Moher D, Straus A, Fergusson DA, Stewart DJ, Jazi M, MacLeod M, Winston B, Marshall J, Hutton B, Walley KR, McIntyre L 2016 eLife View Researchers Clinical research
Intravenous immunoglobulin treatment of spleen cells from patients with immune thrombocytopenia significantly increases the percentage of myeloid-derived suppressor cells Aslam R, Burack WR, Segel GB, McVey M, Spence SA, Semple JW 2017 Br J Haematol View Researchers Basic research
Microfluidic cell-phoresis enabling high-throughput analysis of red blood cell deformability and biophysical screening of antimalarial drugs Santoso AT, Deng X, Lee J-H, Matthews K, Duffy SP, Islamzada E, McFaul SM, Myrand-Lapierre M-E, Ma H 2015 Lab Chip View Researchers New or improved product or process
Multiplexed fluidic plunger mechanism for the measurement of red blood cell deformability Myrand-Lapierre ME, Deng X, Ang RR, Matthews K, Santoso AT, Ma H 2015 Lab Chip View Researchers New or improved product or process
Plant-based food cyanidin-3-glucoside modulates human platelet glycoprotein vi signaling and inhibits platelet activation and thrombus formation Yao Y, Chen Y, Adili R, McKeown T, Chen P, Zhu G, Li D, Ling W, Ni H, Yang Y 2017 J Nutr View Researchers Basic research
Polymer Brushes Hadjesfandiari N, Bajgai MP, Yu K, Brooks DE, Kizhakkedathu JN 2013 Encyclopedia of Polymer Science and Technology View Researchers Basic research
Proteomic analysis of red blood cells from donors exhibiting high hemolysis demonstrates a reduction in membrane?associated proteins involved in the oxidative response Chen D, Schubert P, Devine DV 2017 Transfusion View Researchers Basic research
Red cell transfusion-associated hemolysis in cardiac surgery: an observational cohort study Karkouti K, Callum J, Acker JP, Yip P, Rao V 2017 Anesth Analg View Researchers Clinical research
Reversible hemostatic properties of sulfabetaine/quaternary ammonium modified hyperbranched polyglycerol Wen J, Weinhart M, Lai B, Kizhakkedathu J, Brooks DE 2016 Biomaterials View Researchers Basic research
The effect of timing of gamma-irradiation on hemolysis and potassium release in leukoreduced red cell concentrates stored in SAGM Serrano K, Chen D, Hansen AL, Levin E, Turner TR, Kurach JDR, Acker JP, Devine DV 2014 Vox Sang View Researchers New or improved product or process
Thymic retention of CD4+CD25+FoxP3+ T regulatory cells is associated with their peripheral deficiency and thrombocytopenia in a murine model of immune thrombocytopenia Aslam R, Hu Y, Gebremeskel S, Segel GB, Speck ER, Guo L, Kim M, Ni H, Freedman J, Semple JW 2012 Blood View Researchers Basic research
Two-stage, in silico deconvolution of the lymphocyte compartment of the peripheral whole blood transcriptome in the context of acute kidney allograft rejection Shannon CP, Balshaw R, Ng RT, Wilson-McManus JE, Keown P, McMaster R, McManus BM, Landsberg D, Isbel NM, Knoll G, Tebbutt SJ 2014 PLoS One View Researchers Basic research
Improving Time to Antibiotics for Pediatric Oncology Patients With Fever and Suspected Neutropenia by Applying Lean Principles Geerlinks AV, Digout C, Bernstein M, Chan A, MacPhee S, Pambrun C, Gallant G, Wyatt L, Fernandez CV, Price VE 2018 Pediatric Emergency Care View Researchers New or improved product or process
The effect of tantalum incorporation on the physical and chemical properties of ternary silicon–calcium–phosphorous mesoporous bioactive glasses Mendonca A, Rahman MS, Alhalawani A, Rodriguez O, Gallant RC, Ni H, Clarkin OM, Towler MR 2019 J Biomed Mater Res B Appl Biomater View Researchers Basic research
Trends and outcomes in multicomponent blood transfusion: an 11-year cohort study of a large multisite academic center Perelman I, Saidenberg E, Tinmouth A, Fergusson D 2019 Transfusion View Researchers Clinical research
rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and Fc?Rs Spirig R, Campbell IK, Koernig S, Chen C-G, Lewis BJB, Butcher R, Muir I, Taylor S, Chia J, Leong D, Simmonds J, Scotney P, Schmidt P, Fabri L, Hofmann A, Jordi M, Spycher MO, Cattepoel S, Brasseit J, Panousis C, Rowe T, Branch DR, Baz Morelli A, Kaesermann F, Zuercher AW 2018 J Immunol View Researchers Basic research
Acquired factor XIII deficiency: A review Yan MTS, Rydz N, Goodyear D, Sholzberg M 2018 Transfus Apher Sci View Researchers Other
Comparative pharmacokinetics of two extended half-life FVIII concentrates (Eloctate and Adynovate) in adolescents with hemophilia A: Is there a difference? Carcao MD, Chelle P, Clarke E, Kim L, Tiseo L, Morfini M, Hossain T, Rand ML, Brown C, Edginton AN, Lillicrap D, Iorio A, Blanchette VS 2019 J Thromb Haemost View Researchers Clinical research
Barriers and enablers to source plasma donation by gay, bisexual and other men who have sex with men under revised eligibility criteria: protocol for a multiple stakeholder feasibility study Vesnaver E, Goldman M, O’Brien S, MacPherson P, Butler-Foster T, Lapierre D, Otis J, Devine DV, Germain M, Rosser A, MacDonagh R, Randall T, Osbourne-Sorrell W, Clement-Thorne B, Al-Bakri TB, Rubini KA, Hill NE, Presseau J 2020 Health Res Policy Syst View Researchers MSM research
The Missing Pieces to the Cold-Stored Platelet Puzzle Zhao H, Devine DV 2022 Int J Mol Sci View Researchers Basic research
Use of CRISPR/Cas9 gene editing to improve chimeric antigen-receptor T cell therapy: A systematic review and meta-analysis of preclinical studies Maganti HB, Kirkham AM, Bailey AJM, Shorr R, Kekre N, Pineault N, Allan DS 2022 Cytotherapy View Researchers Clinical research
The international experience of bacterial screen testing of platelet components with automated microbial detection systems: An update Kamel H, Ramirez-Arcos S, McDonald C, ISBT Transfusion-Transmitted Infectious Disease Bacterial Working Party Bacterial Subgroup 2022 Vox Sang View Researchers Benchmarking and standard setting
Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis Almizraq RJ, Frias Boligan K, Lewis BJB, Cen S, Whetstone H, Spirig R, Käsermann F, Campbell IK, von Gunten S, Branch DR 2023 Pharmacology View Researchers Basic research
THP-1 cells transduced with CD16A utilize Fcγ receptor I and III in the phagocytosis of IgG-sensitized human erythrocytes and platelets Gil Gonzalez L, Fernandez-Marrero Y, Norris PAA, Tawhidi Z, Shan Y, Cruz-Leal Y, Won KD, Frias-Boligan K, Branch DR, Lazarus AH 2022 PLoS One View Researchers Basic research
ABO O blood group as a risk factor for platelet reactivity in heparin-induced thrombocytopenia Karnes JH, Rollin J, Giles JB, Martinez KL, Steiner HE, Shaffer CM, Momozawa Y, Inai C, Bombin A, Shi M, Mosley JD, Stanaway I, Selleng K, Thiele T, Mushiroda T, Pouplard C, Heddle NM, Kubo M, Phillips EJ, Warkentin TE, Gruel Y, Greinacher A, Roden DM 2022 Blood View Researchers Basic research
Small Molecule Drugs That Inhibit Phagocytosis Loriamini M, Lewis-Bakker MM, Frias Boligan K, Wang S, Holton MB, Kotra LP, Branch DR 2023 Molecules View Researchers Basic research
Preparing small-dose red cell concentrates (RCCs) for neonatal and pediatric transfusions: Impact of RCC volume, storage, and irradiation Olafson C, William N, Howell A, Beaudin L, Gill B, Clarke G, Stephens S, Lopes-Carvalho D, Lane D, Schubert P, McTaggart K, Acker JP 2022 Transfusion View Researchers New or improved product or process