Our Research Publications
Updated November 2023
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Title | Authors | Year | Journal Sort descending | Link to Article | Intended Audience | Purpose |
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Gender and BCR-ABL transcript type are correlated with molecular response to imatinib treatment in patients with chronic myeloid leukemia | Lin HX, Sjaarda J, Dyck J, Stringer R, Hillis C, Harvey M, Carter R, Ainsworth P, Leber B, Pare G, Sadikovic B | 2016 | Eur J Haematol | View Gender and BCR-ABL transcript type are correlated with molecular response to imatinib treatment in patients with chronic myeloid leukemia | Researchers | Clinical research |
Utilization of a surgical database to provide care and assess perioperative treatment and outcomes in patients with bleeding disorders | Olasupo OO, Haddix C, Nakar C, Maahs J, Greist A, Ghafoor A, Donfield SM, Iorio A, Shapiro AD | 2022 | Eur J Haematol | View Utilization of a surgical database to provide care and assess perioperative treatment and outcomes in patients with bleeding disorders | Health care providers | Benchmarking and standard setting |
T cell-mediated autoimmunity in immune thrombocytopenia | Vrbensky JR, Nazy I, Clare R, Larché M, Arnold DM | 2022 | Eur J Haematol | View T cell-mediated autoimmunity in immune thrombocytopenia | Researchers | Clinical research |
Point of care ultrasound in haemophilia: Building a strong foundation for clinical implementation | Lawson W, Uy M, Strike K, Iorio A, Stein N, Koziol L, Chan A | 2017 | Haemophilia | View Point of care ultrasound in haemophilia: Building a strong foundation for clinical implementation | Health care providers | Clinical research |
Emicizumab state-of-the-art update | Mahlangu J, Iorio A, Kenet G | 2022 | Haemophilia | View Emicizumab state-of-the-art update | Health care providers | Clinical research |
Switching from standard to extended half-life FVIII prophylaxis in haemophilia A: Comparison of factor product use, bleed rates and pharmacokinetics | Nummi V, Lehtinen AE, Iorio A, Szanto T, Lassila R | 2022 | Haemophilia | View Switching from standard to extended half-life FVIII prophylaxis in haemophilia A: Comparison of factor product use, bleed rates and pharmacokinetics | Researchers | Clinical research |
Core outcome set for gene therapy in haemophilia: Results of the coreHEM multistakeholder project | Iorio A, Skinner MW, Clearfield E, Messner D, Pierce GF, Witkop M, Tunis S | 2018 | Haemophilia | View Core outcome set for gene therapy in haemophilia: Results of the coreHEM multistakeholder project | Health care providers | Clinical research |
Comparison of single subject and population-based pharmacokinetics for optimizing prophylaxis with simoctocog alfa in patients with haemophilia A | Astermark J, Olsson A, Chelle P, Täckström K, Walger M, Magnusson M, Iorio A | 2021 | Haemophilia | View Comparison of single subject and population-based pharmacokinetics for optimizing prophylaxis with simoctocog alfa in patients with haemophilia A | Researchers | Clinical research |
Comorbidities in persons with haemophilia aged 60 years or more compared with age-matched people from the general population | Marchesini E, Oliovecchio E, Coppola A, Santagostino E, Radossi P, Castaman G, Valdre L, Santoro C, Tagliaferri A, Ettorre C, Zanon E, Barillari G, Cantori I, Caimi TM, Sottilotta G, Iorio A, Mannucci PM | 2018 | Haemophilia | View Comorbidities in persons with haemophilia aged 60 years or more compared with age-matched people from the general population | Health care providers | Clinical research |
A brief survey of clinicians' perceptions of parent preferences for involvement in obstetrical and perinatal management decisions in haemophilia | Lucier KJ, Movilla RV, Parvizian MK, Siddiqui R, Gabriele EH, Bourque M, MacIsaac J, Moorehead PC, Chan AK, Heddle NM, Lane SJ | 2018 | Haemophilia | View A brief survey of clinicians' perceptions of parent preferences for involvement in obstetrical and perinatal management decisions in haemophilia | Health care providers | Clinical research |
Understanding stakeholder important outcomes and perceptions of equity, acceptability and feasibility of a care model for haemophilia management in the US: a qualitative study | Lane SJ, Sholapur NS, Yeung CH, Iorio A, Heddle NM, Sholzberg M, Pai M | 2016 | Haemophilia | View Understanding stakeholder important outcomes and perceptions of equity, acceptability and feasibility of a care model for haemophilia management in the US: a qualitative study | Health care providers | Other |
Target plasma factor levels for personalized treatment in haemophilia: a Delphi consensus statement | Iorio A, Iserman E, Blanchette V, Dolan G, Escuriola Ettingshausen C, Hermans C, Negrier C, Oldenburg J, Reininger A, Rodriguez-Merchan C, Spannagl M, Valentino LA, Young G, Steinitz-Trost KN, Gringeri A | 2017 | Haemophilia | View Target plasma factor levels for personalized treatment in haemophilia: a Delphi consensus statement | Health care providers | Clinical research |
A systematic review of definitions and reporting of bleeding outcome measures in haemophilia | Chai-Adisaksopha C, Hillis C, Thabane L, Iorio A | 2015 | Haemophilia | View A systematic review of definitions and reporting of bleeding outcome measures in haemophilia | Health care providers | Clinical research |
Patterns of joint damage in severe haemophilia A treated with prophylaxis | Goren R, Pullenayegum E, Blanchette VS, Dover S, Carcao M, Israels SJ, Chan A, Rivard GE, Steele M, Cloutier S, Klaassen RJ, Sinha R, Price VE, Laferriere N, Paradis E, Wu JK, Feldman BM | 2021 | Haemophilia | View Patterns of joint damage in severe haemophilia A treated with prophylaxis | Health care providers | Clinical research |
First analysis of 10-year trends in national factor concentrates usage in haemophilia: data from CHARMS, the Canadian Hemophilia Assessment and Resource Management System | Traore AN, Chan AKC, Webert KE, Heddle N, Ritchie B, St-Louis J, Teitel J, Lillicrap D, Iorio A, Walker I | 2014 | Haemophilia | View First analysis of 10-year trends in national factor concentrates usage in haemophilia: data from CHARMS, the Canadian Hemophilia Assessment and Resource Management System | Health care providers | Clinical research |
Sexual issues in people with haemophilia: Awareness and strategies for overcoming communication barriers | Blamey G, Van Tassel B, Sagermann E, Stain AM, Waterhouse L, Iorio A | 2022 | Haemophilia | View Sexual issues in people with haemophilia: Awareness and strategies for overcoming communication barriers | Researchers | Ethical, legal and social implications research |
What should men living with haemophilia need to know? The perspectives of Canadian men with haemophilia | Arnold E, Lane S, Webert KE, Chan A, Walker I, Tufts J, Rubin S, Poon MC, Heddle NM | 2014 | Haemophilia | View What should men living with haemophilia need to know? The perspectives of Canadian men with haemophilia | Health care providers | Other |
Immunogenicity, efficacy and safety of Nuwiq® (human-cl rhFVIII) in previously untreated patients with severe haemophilia A-Interim results from the NuProtect Study | Liesner RJ, Abashidze M, Aleinikova O, Altisent C, Belletrutti MJ, Borel-Derlon A, Carcao M, Chambost H, Chan AKC, Dubey L, Ducore J, Fouzia NA, Gattens M, Gruel Y, Guillet B, Kavardakova N, El Khorassani M, Klukowska A, Lambert T, Lohade S, Sigaud M, Turea V, Wu JKM, Vdovin V, Pavlova A, Jansen M, Belyanskaya L, Walter O, Knaub S, Neufeld EJ | 2017 | Haemophilia | View Immunogenicity, efficacy and safety of Nuwiq® (human-cl rhFVIII) in previously untreated patients with severe haemophilia A-Interim results from the NuProtect Study | Researchers | Clinical research |
Prophylaxis use of clotting factor replacement products in people with non-severe haemophilia: A review of the literature | Iorio A, Königs C, Reding MT, Rotellini D, Skinner MW, Mancuso ME, Berntorp E | 2023 | Haemophilia | View Prophylaxis use of clotting factor replacement products in people with non-severe haemophilia: A review of the literature | Health care providers | Clinical research |
What should men living with severe haemophilia need to know? The perspectives of Canadian haemophilia health care providers | Lane S, Arnold E, Webert KE, Chan A, Walker I, Heddle NM | 2013 | Haemophilia | View What should men living with severe haemophilia need to know? The perspectives of Canadian haemophilia health care providers | Health care providers | Other |
Past, present and future of haemophilia gene therapy: From vectors and transgenes to known and unknown outcomes | Pierce GF, Iorio A | 2018 | Haemophilia | View Past, present and future of haemophilia gene therapy: From vectors and transgenes to known and unknown outcomes | Health care providers | New or improved product or process |
Factor product utilization and health outcomes in patients with haemophilia A and B on extended half-life concentrates: A Canadian observational study of real-world outcomes | Sun H, Yang M, Poon M-C, Lee A, Robinson KS, Sholzberg M, Wu J, Iorio A, Blanchette V, Carcao M, Klaassen RJ, Jackson S | 2021 | Haemophilia | View Factor product utilization and health outcomes in patients with haemophilia A and B on extended half-life concentrates: A Canadian observational study of real-world outcomes | Researchers | Clinical research |
Switching to extended half-life products in Canada - preliminary data | Keepanasseril A, Stoffman J, Bouskill V, Carcao M, Iorio A, Jackson S | 2017 | Haemophilia | View Switching to extended half-life products in Canada - preliminary data | Health care providers | Clinical research |
Test-retest properties of the Patient Reported Outcomes, Burdens and Experiences (PROBE) questionnaire and its constituent domains | Chai-Adisaksopha C, Skinner MW, Curtis R, Frick N, Nichol MB, Noone D, O'Mahony B, Page D, Stonebraker J, Thabane L, Crowther MA, Iorio A | 2019 | Haemophilia | View Test-retest properties of the Patient Reported Outcomes, Burdens and Experiences (PROBE) questionnaire and its constituent domains | Researchers | Clinical research |
Treatment decision-making among Canadian youth with severe haemophilia: a qualitative approach | Lane SJ, Walker I, Chan AK, Heddle NM, Poon MC, Minuk L, Jardine L, Arnold E, Sholapur N, Webert KE | 2015 | Haemophilia | View Treatment decision-making among Canadian youth with severe haemophilia: a qualitative approach | Health care providers | Clinical research |
Converting factor and nonfactor usage into a single metric to facilitate benchmarking the resources consumed for haemophilia care across jurisdictions and over time | Stonebraker JS, O'Mahony B, Noone D, Iorio A | 2021 | Haemophilia | View Converting factor and nonfactor usage into a single metric to facilitate benchmarking the resources consumed for haemophilia care across jurisdictions and over time | Researchers | Benchmarking and standard setting |
Evaluation of the sexual health in people living with hemophilia | Germini F, Chai-Adisaksopha C, Pete D, Curtis R, Frick N, Nichol MB, Noone D, O'Mahony B, Page D, Stonebraker JS, Thabane L, Crowther MA, Skinner MW, Iorio A | 2021 | Haemophilia | View Evaluation of the sexual health in people living with hemophilia | Researchers | Clinical research |
The importance of haemophilia treatment centre administrators in patient care | Almonte T, Decker K, Seroski W, Walker I, Webert K, Bos C, Strike K, Waterhouse L, Goldsmith R, Chan AK | 2012 | Haemophilia | View The importance of haemophilia treatment centre administrators in patient care | Health care providers | Other |
Challenges and key lessons from the design and implementation of an international haemophilia registry supported by a pharmaceutical company | Hay CRM, Shima M, Makris M, Jiménez-Yuste V, Oldenburg J, Fischer K, Iorio A, Skinner MW, Santagostino E, von Mackensen S, Kessler CM | 2020 | Haemophilia | View Challenges and key lessons from the design and implementation of an international haemophilia registry supported by a pharmaceutical company | Researchers | Clinical research |
Rate and appropriateness of polypharmacy in older patients with hemophilia compared with age-matched controls | Mannucci PM, Nobili A, Marchesini E, Oliovecchio E, Cortesi L, Coppola A, Santagostino E, Radossi P, Castaman G, Valdrè L, Santoro C, Tagliaferri A, Ettorre C, Zanon E, Barillari G, Cantori I, Caimi TM, Sottilotta G, Peyvandi F, Iorio A | 2018 | Haemophilia | View Rate and appropriateness of polypharmacy in older patients with hemophilia compared with age-matched controls | Health care providers | Clinical research |
Exploring some intersections between pharmacokinetics, factor VIII measurement and human morphometrics - impact of recent advances in haemophilia study design on our understanding of optimal haemophilia treatment | Iorio A, Edginton AN | 2017 | Haemophilia | View Exploring some intersections between pharmacokinetics, factor VIII measurement and human morphometrics - impact of recent advances in haemophilia study design on our understanding of optimal haemophilia treatment | Researchers | Clinical research |
A case of vertical transmission of Chagas Disease contracted via blood transfusion in Canada | Fearon MA, Scalia V, Huang M, Dines I, Ndao M | 2013 | Can J Infect Dis Med Microbiol | View A case of vertical transmission of Chagas Disease contracted via blood transfusion in Canada | Health care providers | Clinical research |
Aggregates in platelet concentrates | van der Meer PF, Dumont LJ, Lozano M, Bondar N, Wong J, Ismay S, Pink J, Nussbaumer W, Coene J, Feys HB, Compernolle V, Devine DV, Howe D, Lin CK, Sun J, Ringwald J, Strasser EF, Eckstein R, Seltsam A, Perseghin P, Proserpio P, Wakamoto S, Akino M, Takamoto S, Tadokoro K, Teo D, Shu PH, Chua SS, Jimenez-Marco T, Lozano M, Cid J, Castro E, Munoz I, Gulliksson H, Sandgren P, Thomas S, Petrik J, McColl K, Kamel H, Dugger J, Sweeney JD, Gorlin JB, Sutor LJ, Heath D, Sayers MH | 2015 | Vox Sang | View Aggregates in platelet concentrates | Blood operators | Benchmarking and standard setting |
Bacteria can proliferate in thawed cryoprecipitate stored at room temperature for longer than 4 h | Ramirez-Arcos S, Jenkins C, Sheffield W | 2017 | Vox Sang | View Bacteria can proliferate in thawed cryoprecipitate stored at room temperature for longer than 4 h | Researchers | Basic research |
Implementation and public acceptability: lessons from food irradiation and how they might apply to pathogen reduction in blood products | Heddle NM, Lane SJ, Sholapur N, Arnold E, Newbold B, Eyles J, Webert KE | 2014 | Vox Sang | View Implementation and public acceptability: lessons from food irradiation and how they might apply to pathogen reduction in blood products | Blood operators | Other |
Vox Sanguinis international forum on platelet cryopreservation: summary | Cohn CS, Dumont LJ, Lozano M, Marks D, Johnson L, Ismay S, Bondar N, T'Sas F, Yokoyama APH, Kutner JM, Acker J, Bohonek M, Sailliol A, Martinaud C, Poglod R, Antoniewicz-Papis J, Lachert E, Pun P, Lu J, Cid J, Guijarro F, Puig L, Gerber B, Alberio L, Schanz U, Buser A, Noorman F, Zoodsma M, van der Meer PF, de Korte D, Wagner S, O'Neill M | 2017 | Vox Sang | View Vox Sanguinis international forum on platelet cryopreservation: summary | Blood operators | New or improved product or process |
Feasibility of photoacoustic imaging for the non-invasive quality management of stored blood bags | Pinto RN, Hysi E, Bagga K, Sebastian JA, Douplik A, Acker JP, Kolios MC | 2019 | Vox Sang | View Feasibility of photoacoustic imaging for the non-invasive quality management of stored blood bags | Researchers | New or improved product or process |
Development and evaluation of stem cell collection procedure diagrams to support the education and recruitment of committed stem cell donors | Fingrut W, Cuperfain AB, Chan SWS, Ptak E, Kahlon M, Dhaliwal J, Naidu A, Wang YG, Baribeau O, Mahmoudi T, Lee A, Suppiah R, Luo OD, Green M, Weiss JT, Mercer D, Elmoazzen H, Petraszko T, Allan D | 2020 | Vox Sang | View Development and evaluation of stem cell collection procedure diagrams to support the education and recruitment of committed stem cell donors | Blood operators | New or improved product or process |
Frequency and timing of all-cause deaths in visits involving suspected transfusion reactions, and the significance of cardiopulmonary disturbances | McVey MJ, Cohen R, Arsenault V, Escorcia A, Tasmin F, Pendergrast J, Lieberman L, Lin Y, Callum J, Cserti-Gazdewich C | 2021 | Vox Sang | View Frequency and timing of all-cause deaths in visits involving suspected transfusion reactions, and the significance of cardiopulmonary disturbances | Health care providers | Clinical research |
Vox Sanguinis International forum on the selection and preparation of blood components for intrauterine transfusion | Clarke G, Bodnar M, Lozano M, Nadarajan VS, Lee C, Baud D, Canellini G, Gleich-Nagel T, Torres OW, Rey PL, Bub CB, Kutner JM, Castilho L, Saifee NH, Delaney M, Nester T, Wikman A, Tiblad E, Pierelli L, Matteocci A, Maresca M, Maisonneuve E, Cortey A, Jouannic J-M, Fornells J, Albersen A, de Haas M, Oepkes D, Lieberman L | 2020 | Vox Sang | View Vox Sanguinis International forum on the selection and preparation of blood components for intrauterine transfusion | Health care providers | Benchmarking and standard setting |
Current challenges of severe acute respiratory syndrome coronavirus 2 seroprevalence studies among blood donors: A scoping review | Saeed S, Uzicanin S, Lewin A, Lieshout-Krikke R, Faddy H, Erikstrup C, Osiowy C, Seed CR, Steele WR, Davison K, Custer B, O'Brien SF, Assessment SR, Policy Sub-group of the Transfusion Transmitted Infectious Diseases Working Party of the International Society of Blood Transfusion | 2022 | Vox Sang | View Current challenges of severe acute respiratory syndrome coronavirus 2 seroprevalence studies among blood donors: A scoping review | Researchers | Basic research |
International Forum on Walking Blood Bank Programmes: Responses | Martinaud C, Scorer T, Lozano M, Miles A, Fitchett G, Ba A, Wikman A, Nimberger-Hansson P, Enbuske S, Bohon?k M, Devine D, Beckett AN, Mbanya D, T'Sas F, Degueldre J, Chueca M, Dedome E, Apelseth T, Strandenes G, Wendel S, Fachini R, Olszewski A, Dupont C, Glassberg E, Shinar E, Taylor AL, Corley JB, Nadarajan VS, Dunbar N | 2021 | Vox Sang | View International Forum on Walking Blood Bank Programmes: Responses | Blood operators | New or improved product or process |
Validation of a flow-cytometry-based red blood cell antigen phenotyping method | Liwski R, Clarke G, Cheng C, Abidi SSR, Abidi SR, Quinn JG | 2023 | Vox Sang | View Validation of a flow-cytometry-based red blood cell antigen phenotyping method | Health care providers | New or improved product or process |
Evaluation of the appropriateness of frozen plasma usage after introduction of prothrombin complex concentrates: a retrospective study | Shih AW, Kolesar E, Ning S, Manning N, Arnold DM, Crowther MA | 2015 | Vox Sang | View Evaluation of the appropriateness of frozen plasma usage after introduction of prothrombin complex concentrates: a retrospective study | Health care providers | New or improved product or process |
Research initiatives of blood services worldwide in response to the covid-19 pandemic | O'Brien SF, Lieshout-Krikke RW, Lewin A, Erikstrup C, Steele WR, Uzicanin S, Custer B, the Surveillance RA, Policy Sub-group of the ISBT Transfusion Transmitted Infectious Diseases Working Party | 2021 | Vox Sang | View Research initiatives of blood services worldwide in response to the covid-19 pandemic | Researchers | Clinical research |
An international comparison of HIV prevalence and incidence in blood donors and general population: a BEST Collaborative study | Germain M, Grégoire Y, Custer BS, Goldman M, Bravo M, Kamel H, Davison K, Field S, van den Hurk K, van de Laar TJW, Irving DO, Jones A, Liumbruno G, Morley S, O’Brien SF, Pillonel J, Steinsvåg CT, Takanashi M, Tsuno NH, Vesga Carasa MA, Wendel S, Vassallo RR, Tiberghien P, for the BEST Collaborative | 2021 | Vox Sang | View An international comparison of HIV prevalence and incidence in blood donors and general population: a BEST Collaborative study | Researchers | Benchmarking and standard setting |
Use of selective phenotyping and genotyping to identify rare blood donors in Canada | Tordon B, Montemayor C, Clarke G, O'Brien SF, Goldman M | 2023 | Vox Sang | View Use of selective phenotyping and genotyping to identify rare blood donors in Canada | Blood operators | Clinical research |
International survey on the impact of parasitic infections: frequency of transmission and current mitigation strategies | Leiby DA, O'Brien SF, Wendel S, Nguyen ML, Delage G, Devare SG, Hardiman A, Nakhasi HL, Sauleda S, Bloch EM, WPTTID Subgroup on Parasites | 2019 | Vox Sang | View International survey on the impact of parasitic infections: frequency of transmission and current mitigation strategies | Researchers | Clinical research |
International Forum on Occult hepatitis B infection and transfusion safety | Seed CR, Allain J-P, Lozano M, Laperche S, Gallian P, Gross S, Kwon S-Y, Oh EY, Kim JN, Chua SS, Lam S, Ang AL, Tsoi W-C, Hewitt PE, Davison KL, Tettmar K, O'Flaherty N, Boland F, Williams P, Pomeroy L, Wendel S, Fachini R, Scuracchio P, Carminato P, Fearon M, O'Brien SF, Delage G, Kiely P, Hoad V, Matsubayashi K, Satake M, Taira R, Stramer SL, Sauleda S, Bes M, Piron M, El Ekiaby M, Vermeulen M, Levi?nik Stezinar S, Nograšek P, Jarvis LM, Petrik J, Charlewood R, Flanagan P, Grabarczyk P, Kopacz A, ??towska M, Seifried E, Schmidt M | 2019 | Vox Sang | View International Forum on Occult hepatitis B infection and transfusion safety | Researchers | Benchmarking and standard setting |
The systematic use of evidence-based methodologies and technologies enhances shared decision-making in the 2018 International Consensus Conference on Patient Blood Management | Van Remoortel H, Aranko K, Mueller MM, De Buck E, Devine D, Folléa G, Meybohm P, Tiberghien P, Wood EM, Vandekerckhove P, Seifried E | 2020 | Vox Sang | View The systematic use of evidence-based methodologies and technologies enhances shared decision-making in the 2018 International Consensus Conference on Patient Blood Management | Researchers | Benchmarking and standard setting |