Our Research Publications
Updated November 2023
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Title | Authors | Year | Journal | Link to Article | Intended Audience Sort descending | Purpose |
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An intron c.149-2632T>A change in RHD is associated with aberrant transcription and very weak D phenotype | Floch A, Vege S, Berardi P, Hannon J, Ochoa-Garay G, Lomas-Francis C, Westhoff CM | 2022 | Transfusion | View An intron c.149-2632T>A change in RHD is associated with aberrant transcription and very weak D phenotype | Researchers | Clinical research |
Donor-recipient sex is associated with transfusion-related outcomes in critically ill patients | Alshalani A, Uhel F, Cremer OL, Schultz MJ, de Vooght KMK, van Bruggen R, Acker JP, Juffermans NP | 2022 | Blood Adv | View Donor-recipient sex is associated with transfusion-related outcomes in critically ill patients | Researchers | Clinical research |
Humoral and Cellular Response of Transplant Recipients to a Third Dose of mRNA SARS-CoV-2 Vaccine: A Systematic Review and Meta-analysis | Bailey AJM, Maganti HB, Cheng W, Shorr R, Arianne Buchan C, Allan DS | 2023 | Transplantation | View Humoral and Cellular Response of Transplant Recipients to a Third Dose of mRNA SARS-CoV-2 Vaccine: A Systematic Review and Meta-analysis | Researchers | Basic research |
A Survey of Patient Experience in CML: American and Canadian Perspectives | Hillis C, Flynn KE, Goldman EH, Moreira-Lucas TS, Visentini J, Dorman S, Ballinger R, Byrnes HF, De Palma A, Barbier V, Machado L, Atallah E | 2023 | Patient Prefer Adherence | View A Survey of Patient Experience in CML: American and Canadian Perspectives | Researchers | Clinical research |
Database-driven research and big data analytic approaches in transfusion medicine | Ning S, Li N, Barty R, Arnold D, Heddle NM | 2022 | Transfusion | View Database-driven research and big data analytic approaches in transfusion medicine | Researchers | Clinical research |
A positive blood culture is associated with a lower haemoglobin increment in hospitalized patients after red blood cell transfusion | Qadri SM, Liu Y, Barty RL, Heddle NM, Sheffield WP | 2022 | Vox Sang | View A positive blood culture is associated with a lower haemoglobin increment in hospitalized patients after red blood cell transfusion | Researchers | Clinical research |
Concentré de recherche: Évaluation de la sécurité des pompes à perfusion pour les transfusions de globules rouges | Wolfe A | 2022 | Blood.ca website | View Concentré de recherche: Évaluation de la sécurité des pompes à perfusion pour les transfusions de globules rouges | Researchers | Benchmarking and standard setting |
Activated NK cells cause placental dysfunction and miscarriages in fetal alloimmune thrombocytopenia | Yougbare I, Tai WS, Zdravic D, Oswald BE, Lang S, Zhu G, Leong-Poi H, Qu D, Yu L, Dunk C, Zhang J, Sled JG, Lye SJ, Brkic J, Peng C, Hoglund P, Croy BA, Adamson SL, Wen XY, Stewart DJ, Freedman J, Ni H | 2017 | Nat Commun | View Activated NK cells cause placental dysfunction and miscarriages in fetal alloimmune thrombocytopenia | Researchers | Basic research |
Assessing the influence of component processing and donor characteristics on quality of red cell concentrates using quality control data | Jordan A, Chen D, Yi QL, Kanias T, Gladwin MT, Acker JP | 2016 | Vox Sang | View Assessing the influence of component processing and donor characteristics on quality of red cell concentrates using quality control data | Researchers | Basic research |
CD44 antibodies and immune thrombocytopenia in the amelioration of murine inflammatory arthritis | Mott PJ, Lazarus AH | 2013 | PLoS One | View CD44 antibodies and immune thrombocytopenia in the amelioration of murine inflammatory arthritis | Researchers | Basic research |
C-reactive protein enhances murine antibody-mediated transfusion-related acute lung injury | Kapur R, Kim M, Shanmugabhavananthan S, Liu J, Li Y, Semple JW | 2015 | Blood | View C-reactive protein enhances murine antibody-mediated transfusion-related acute lung injury | Researchers | Basic research |
Development and testing of a stepwise thaw and dilute protocol for cryopreserved umbilical cord blood units | Pasha R, Elmoazzen H, Pineault N | 2017 | Transfusion | View Development and testing of a stepwise thaw and dilute protocol for cryopreserved umbilical cord blood units | Researchers | New or improved product or process |
Enhanced Nitrite Reductase Activity and Its Correlation with Oxygen Affinity in Hemoglobin Bis-Tetramers | Wang A, Kluger R | 2016 | Biochemistry | View Enhanced Nitrite Reductase Activity and Its Correlation with Oxygen Affinity in Hemoglobin Bis-Tetramers | Researchers | Basic research |
Fluorous Analogue of Chloramine-T: Preparation, X-ray Structure Determination, and Use as an Oxidant for Radioiodination and s-Tetrazine Synthesis | Dzandzi JPK, Beckford Vera DR, Genady AR, Albu SA, Eltringham-Smith LJ, Capretta A, Sheffield WP, Valliant JF | 2015 | J Org Chem | View Fluorous Analogue of Chloramine-T: Preparation, X-ray Structure Determination, and Use as an Oxidant for Radioiodination and s-Tetrazine Synthesis | Researchers | Basic research |
Herpesviruses enhance fibrin clot lysis | Gershom ES, Vanden Hoek AL, Meixner SC, Sutherland MR, Pryzdial EL | 2012 | Thromb Haemost | View Herpesviruses enhance fibrin clot lysis | Researchers | Basic research |
Immunoglobulin G Fc glycans are not essential for antibody-mediated immune suppression to murine erythrocytes | Marjoram D, Cruz-Leal Y, Bernardo L, Le NPL, Crispin M, Yu X, Uchikawa M, Lazarus AH | 2017 | Blood | View Immunoglobulin G Fc glycans are not essential for antibody-mediated immune suppression to murine erythrocytes | Researchers | Basic research |
In-Gel Technology for PCR Genotyping and Pathogen Detection | Atrazhev A, Manage DP, Stickel AJ, Crabtree HJ, Pilarski LM, Acker JP | 2010 | Anal Chem | View In-Gel Technology for PCR Genotyping and Pathogen Detection | Researchers | New or improved product or process |
Kruppel-like factor 1 (KLF1), KLF2, and Myc control a regulatory network essential for embryonic erythropoiesis | Pang CJ, Lemsaddek W, Alhashem YN, Bondzi C, Redmond LC, Ah-Son N, Dumur CI, Archer KJ, Haar JL, Lloyd JA, Trudel M | 2012 | Mol Cell Biol | View Kruppel-like factor 1 (KLF1), KLF2, and Myc control a regulatory network essential for embryonic erythropoiesis | Researchers | Basic research |
Novel evidence that pituitary gonadotropins directly stimulate human leukemic cells-studies of myeloid cell lines and primary patient AML and CML cells | Abdelbaset-Ismail A, Borkowska S, Janowska-Wieczorek A, Tonn T, Rodriguez C, Moniuszko M, Bolkun L, Koloczko J, Eljaszewicz A, Ratajczak J, Ratajczak MZ, Kucia M | 2015 | Oncotarget | View Novel evidence that pituitary gonadotropins directly stimulate human leukemic cells-studies of myeloid cell lines and primary patient AML and CML cells | Researchers | Basic research |
Peculiarities of studying the effects of pathogen reduction technologies on platelets | Osman A, Hitzler WE, Provost P | 2016 | Proteomics Clin Appl | View Peculiarities of studying the effects of pathogen reduction technologies on platelets | Researchers | Basic research |
Prevention of hemolytic disease of the fetus and newborn: what have we learned from animal models? | Cruz-Leal Y, Marjoram D, Lazarus AH | 2017 | Curr Opin Hematol | View Prevention of hemolytic disease of the fetus and newborn: what have we learned from animal models? | Researchers | Basic research |
Raman spectroscopy as a novel tool for monitoring biochemical changes and inter-donor variability in stored red blood cell units | Atkins CG, Buckley K, Chen D, Schulze HG, Devine DV, Blades MW, Turner RFB | 2016 | Analyst | View Raman spectroscopy as a novel tool for monitoring biochemical changes and inter-donor variability in stored red blood cell units | Researchers | New or improved product or process |
Targeting FcRs to treat antibody-dependent autoimmunity | Yu X, Lazarus AH | 2016 | Autoimmun Rev | View Targeting FcRs to treat antibody-dependent autoimmunity | Researchers | Other |
The impact of perioperative red blood cell transfusions in patients undergoing liver resection: a systematic review | Bennett S, Baker LK, Martel G, Shorr R, Pawlik TM, Tinmouth A, McIsaac DI, Hébert PC, Karanicolas PJ, McIntyre L, Turgeon AF, Barkun J, Fergusson D | 2017 | HPB | View The impact of perioperative red blood cell transfusions in patients undergoing liver resection: a systematic review | Researchers | Clinical research |
The transcription factor Miz-1 is required for embryonic and stress-induced erythropoiesis but dispensable for adult erythropoiesis | Kosan C, Rashkovan M, Ross J, Schaffer AM, Saba I, Lemsaddek W, Trudel M, Moroy T | 2014 | Am J Blood Res | View The transcription factor Miz-1 is required for embryonic and stress-induced erythropoiesis but dispensable for adult erythropoiesis | Researchers | Basic research |
Transfusion requirements in cardiac surgery III (TRICS III): study design of a randomized controlled trial | Shehata N, Whitlock R, Fergusson DA, Thorpe KE, MacAdams C, Grocott HP, Rubens F, Fremes S, Lellouche F, Bagshaw S, Royse A, Rosseel PM, Hare G, Medicis E, Hudson C, Belley-Cote E, Bainbridge D, Kent B, Shaw A, Byrne K, Syed S, Royse CF, McGuiness S, Hall J, Mazer CD | 2018 | J Cardiothorac Vasc Anesth | View Transfusion requirements in cardiac surgery III (TRICS III): study design of a randomized controlled trial | Researchers | Clinical research |
Antimicrobial peptides: an effective approach to prevent bacterial biofilm formation in platelet concentrates | Alabdullatif M, Atreya CD, Ramirez-Arcos S | 2018 | Transfusion | View Antimicrobial peptides: an effective approach to prevent bacterial biofilm formation in platelet concentrates | Researchers | New or improved product or process |
Pathogen inactivation strategies to improve blood safety: Let's not throw pathogen-reduced platelets out with their bath water | Devine DV | 2018 | JAMA Oncol | View Pathogen inactivation strategies to improve blood safety: Let's not throw pathogen-reduced platelets out with their bath water | Researchers | New or improved product or process |
Systematic review of rituximab for autoimmune diseases: a potential alternative to intravenous immune globulin | MacIsaac J, Siddiqui R, Jamula E, Li N, Baker S, Webert KE, Evanovitch D, Heddle NM, Arnold DM | 2018 | Transfusion | View Systematic review of rituximab for autoimmune diseases: a potential alternative to intravenous immune globulin | Researchers | Clinical research |
GPIb? is required for platelet-mediated hepatic thrombopoietin generation | Xu M, Li J, Neves MAD, Zhu G, Carrim N, Yu R, Gupta S, Marshall J, Rotstein O, Peng J, Hou M, Kunishima S, Ware J, Branch DR, Lazarus A, Ruggeri ZM, Freedman J, Ni H | 2018 | Blood | View GPIb? is required for platelet-mediated hepatic thrombopoietin generation | Researchers | Basic research |
Prevalence of Babesia in Canadian blood donors: June–October 2018 | Tonnetti L, O'Brien SF, Grégoire Y, Proctor MC, Drews SJ, Delage G, Fearon MA, Brès V, Linnen JM, Stramer SL | 2019 | Transfusion | View Prevalence of Babesia in Canadian blood donors: June–October 2018 | Researchers | Clinical research |
Antiviral anticoagulation | Pryzdial ELG, Sutherland MR, Lin BH, Horwitz M | 2020 | Res Pract Thromb Haemost | View Antiviral anticoagulation | Researchers | Basic research |
FcgammaRI and FcgammaRIII on splenic macrophages mediate phagocytosis of anti-glycoprotein IIb/IIIa autoantibody-opsonized platelets in immune thrombocytopenia | Norris PAA, Segel GB, Burack WR, Sachs UJ, Lissenberg-Thunnissen SN, Vidarsson G, Bayat B, Cserti-Gazdewich CM, Callum J, Lin Y, Branch D, Kapur R, Semple JW, Lazarus AH | 2021 | Haematologica | View FcgammaRI and FcgammaRIII on splenic macrophages mediate phagocytosis of anti-glycoprotein IIb/IIIa autoantibody-opsonized platelets in immune thrombocytopenia | Researchers | Basic research |
Pragmatic, double-blind, randomised trial evaluating the impact of red blood cell donor sex on recipient mortality in an academic hospital population: the innovative Trial Assessing Donor Sex (iTADS) protocol | Fergusson DA, Chassé M, Tinmouth A, Acker JP, English S, Forster AJ, Hawken S, Shehata N, Thavorn K, Wilson K, Tuttle A, Perelman I, Cober N, Maddison H, Tokessy M | 2021 | BMJ Open | View Pragmatic, double-blind, randomised trial evaluating the impact of red blood cell donor sex on recipient mortality in an academic hospital population: the innovative Trial Assessing Donor Sex (iTADS) protocol | Researchers | Clinical research |
A simple protein-based surrogate neutralization assay for SARS-CoV-2 | Abe KT, Li Z, Samson R, Samavarchi-Tehrani P, Valcourt EJ, Wood H, Budylowski P, Dupuis Ii AP, Girardin RC, Rathod B, Wang J, Barrios-Rodiles M, Colwill K, McGeer A, Mubareka S, Gommerman JL, Durocher Y, Ostrowski M, McDonough KA, Drebot MA, Drews SJ, Rini JM, Gingras AC | 2020 | JCI Insight | View A simple protein-based surrogate neutralization assay for SARS-CoV-2 | Researchers | New or improved product or process |
DNA Mediated Blood Coagulation: Extracellular DNA Accelerates Fibrinogen Polymerization By Thrombin Independent of Contact Pathway | Vappala S, Straus S, Pryzdial EL, Conway E, Kizhakkedathu J | 2021 | Blood | View DNA Mediated Blood Coagulation: Extracellular DNA Accelerates Fibrinogen Polymerization By Thrombin Independent of Contact Pathway | Researchers | Basic research |
Reconstituted cryopreserved platelets synthesize proteins during short-term storage and packaging a defined subset into microvesicles | Schubert P, Johnson L, Culibrk B, Chen Z, Tan S, Marks DC, Devine DV | 2021 | Transfusion | View Reconstituted cryopreserved platelets synthesize proteins during short-term storage and packaging a defined subset into microvesicles | Researchers | New or improved product or process |
Dimethyl sulfoxide-free cryopreservation solutions for hematopoietic stem cell grafts | Kaushal R, Jahan S, McGregor C, Pineault N | 2022 | Cytotherapy | View Dimethyl sulfoxide-free cryopreservation solutions for hematopoietic stem cell grafts | Researchers | New or improved product or process |
A Higher Antibody Response Is Generated With a 6- to 7-Week (vs Standard) Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Dosing Interval | Grunau B, Asamoah-Boaheng M, Lavoie PM, Karim ME, Kirkham TL, Demers PA, Barakauskas V, Marquez AC, Jassem AN, O'Brien SF, Drews SJ, Haig S, Cheskes S, Goldfarb DM | 2021 | Clin Infect Dis | View A Higher Antibody Response Is Generated With a 6- to 7-Week (vs Standard) Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Dosing Interval | Researchers | Clinical research |
Co-administration of FVIII with IVIG reduces immune response to FVIII in hemophilia A mice | Afraz S, Stevic I, Matino D, Wen J, Atkinson H, Chan AKC, Hortelano G | 2022 | Sci Rep | View Co-administration of FVIII with IVIG reduces immune response to FVIII in hemophilia A mice | Researchers | Clinical research |
Thymic stromal lymphopoietin induces platelet mitophagy and promotes thrombosis in Kawasaki disease | Fu L, MacKeigan DT, Gong Q, Che D, Xu Y, Pi L, Sun C, Yu H, Chen K, Zhou H, Jiang Z, Wang Z, Zhang L, Cerenzia EG, Ni H, Gu X | 2023 | Brit J Haem | View Thymic stromal lymphopoietin induces platelet mitophagy and promotes thrombosis in Kawasaki disease | Researchers | Clinical research |
Blood donor eligibility criteria for medical conditions: A BEST collaborative study | Jacquot C, Tiberghien P, van den Hurk K, Ziman A, Shaz B, Apelseth TO, Goldman M, The Biomedical Excellence for Safer Transfusion Collaborative | 2022 | Vox Sang | View Blood donor eligibility criteria for medical conditions: A BEST collaborative study | Researchers | Benchmarking and standard setting |
SARS-CoV-2 Seroprevalence among Canadian Blood Donors: The Advance of Omicron | O’Brien SF, Caffrey N, Yi Q-L, Pambrun C, Drews SJ | 2022 | Viruses | View SARS-CoV-2 Seroprevalence among Canadian Blood Donors: The Advance of Omicron | Researchers | Clinical research |
Prevalence of selected bleeding and thrombotic events in persons with hemophilia versus the general population: A scoping review | Shapiro AD, Hardesty BM, Peyvandi F, Iorio A | 2023 | Res Pract Thromb Haemost | View Prevalence of selected bleeding and thrombotic events in persons with hemophilia versus the general population: A scoping review | Researchers | Clinical research |
Animal model of fetal and neonatal immune thrombocytopenia: role of neonatal Fc receptor in the pathogenesis and therapy | Chen P, Li C, Lang S, Zhu G, Reheman A, Spring CM, Freedman J, Ni H | 2010 | Blood | View Animal model of fetal and neonatal immune thrombocytopenia: role of neonatal Fc receptor in the pathogenesis and therapy | Researchers | Basic research |
Comparison of detection methods for cell surface globotriaosylceramide | Kim M, Binnington B, Sakac D, Fernandes KR, Shi SP, Lingwood CA, Branch DR | 2011 | J Immunol Methods | View Comparison of detection methods for cell surface globotriaosylceramide | Researchers | Basic research |
Defining Significant Events for Neonatal and Pediatric Transport: Results of a Combined Delphi and Consensus Meeting Process | Gunz A, McNally J, Whyte H, O'Hearn K, Foster J, Parker M, Dhanani S | 2016 | J Pediatr Intensive Care | View Defining Significant Events for Neonatal and Pediatric Transport: Results of a Combined Delphi and Consensus Meeting Process | Researchers | Clinical research |
Differential Expression Analysis by RNA-Seq Reveals Perturbations in the Platelet mRNA Transcriptome Triggered by Pathogen Reduction Systems | Osman A, Hitzler WE, Ameur A, Provost P | 2015 | PLoS One | View Differential Expression Analysis by RNA-Seq Reveals Perturbations in the Platelet mRNA Transcriptome Triggered by Pathogen Reduction Systems | Researchers | Basic research |
Effect of platelet additive solution on bacterial dynamics and their influence on platelet quality in stored platelet concentrates | Greco CA, Zhang JG, Kalab M, Yi Q-L, Ramirez-Arcos SM, Gyongyossy-Issa MIC | 2010 | Transfusion | View Effect of platelet additive solution on bacterial dynamics and their influence on platelet quality in stored platelet concentrates | Researchers | Basic research |
E-selectin mediated adhesion and migration of endothelial colony forming cells is enhanced by SDF-1alpha/CXCR4 | Sun J, Li Y, Graziani GM, Filion L, Allan DS | 2013 | PLoS One | View E-selectin mediated adhesion and migration of endothelial colony forming cells is enhanced by SDF-1alpha/CXCR4 | Researchers | Basic research |