Our Research Publications
Updated November 2023
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Title | Authors | Year | Journal | Link to Article | Intended Audience Sort descending | Purpose |
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Bioorthogonal phase-directed copper-catalyzed azide–alkyne cycloaddition (PDCuAAC) coupling of selectively cross-linked superoxide dismutase dimers produces a fully active bis-dimer | Siren EM, Singh S, Kluger R | 2015 | Org Biomol Chem | View Bioorthogonal phase-directed copper-catalyzed azide–alkyne cycloaddition (PDCuAAC) coupling of selectively cross-linked superoxide dismutase dimers produces a fully active bis-dimer | Researchers | Basic research |
Cardiorespiratory pathogenesis of sickle cell disease in a mouse model | Ren J, Ding X, Trudel M, Greer JJ, MacLean JE | 2017 | Sci Rep | View Cardiorespiratory pathogenesis of sickle cell disease in a mouse model | Researchers | Basic research |
Corticosteroids compared with intravenous immunoglobulin for the treatment of immune thrombocytopenia in pregnancy | Sun D, Shehata N, Ye XY, Gregorovich S, De France B, Arnold DM, Shah PS, Malinowski AK | 2016 | Blood | View Corticosteroids compared with intravenous immunoglobulin for the treatment of immune thrombocytopenia in pregnancy | Researchers | Clinical research |
Determining the inventory impact of extended shelf life platelets with a network simulation model | Blake J | 2017 | Transfusion | View Determining the inventory impact of extended shelf life platelets with a network simulation model | Researchers | New or improved product or process |
Encapsulation of factor IX-engineered mesenchymal stem cells in fibrinogen-alginate microcapsules enhances their viability and transgene secretion | Sayyar B, Dodd M, Wen J, Ma S, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G | 2012 | J Tissue Eng | View Encapsulation of factor IX-engineered mesenchymal stem cells in fibrinogen-alginate microcapsules enhances their viability and transgene secretion | Researchers | Basic research |
Evidence for a novel mechanism independent of myocardial iron in beta-thalassemia cardiac pathogenesis | Stoyanova E, Cloutier G, Felfly H, Lemsaddek W, Ah-Son N, Trudel M | 2012 | PLoS One | View Evidence for a novel mechanism independent of myocardial iron in beta-thalassemia cardiac pathogenesis | Researchers | Basic research |
Fibronectin-Alginate microcapsules improve cell viability and protein secretion of encapsulated Factor IX-engineered human mesenchymal stromal cells | Sayyar B, Dodd M, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G | 2014 | Artif Cells Nanomed Biotechnol | View Fibronectin-Alginate microcapsules improve cell viability and protein secretion of encapsulated Factor IX-engineered human mesenchymal stromal cells | Researchers | Basic research |
Immunocamouflage: The biophysical basis of immunoprotection by grafted methoxypoly(ethylene glycol) (mPEG) | Le Y, Scott MD | 2010 | Acta Biomater | View Immunocamouflage: The biophysical basis of immunoprotection by grafted methoxypoly(ethylene glycol) (mPEG) | Researchers | Basic research |
Increasing efficiency in protein-protein coupling: subunit-directed acetylation and phase-directed CuAAC ("click coupling") in the formation of hemoglobin bis-tetramers | Wang A, Kluger R | 2014 | Biochemistry | View Increasing efficiency in protein-protein coupling: subunit-directed acetylation and phase-directed CuAAC ("click coupling") in the formation of hemoglobin bis-tetramers | Researchers | Basic research |
Mitochondrial damage-associated molecular patterns in blood transfusion products | Marcoux G, Boilard E | 2017 | ISBT Sci Ser | View Mitochondrial damage-associated molecular patterns in blood transfusion products | Researchers | Basic research |
Pathogenesis and Therapeutic Mechanisms in Immune Thrombocytopenia (ITP) | Zufferey A, Kapur R, Semple J | 2017 | J Clin Med | View Pathogenesis and Therapeutic Mechanisms in Immune Thrombocytopenia (ITP) | Researchers | Basic research |
Red blood cell antibody induced anemia causes differential degrees of tissue hypoxia in kidney and brain | Mistry N, Mazer CD, Sled JG, Lazarus AH, Cahill LS, Solish M, Zhou Y-Q, Romanova N, Hare AG, Doctor A, Fisher JA, Brunt KR, Simpson JA, Hare GMT | 2018 | Am J Physiol Regul Integr Comp Physiol | View Red blood cell antibody induced anemia causes differential degrees of tissue hypoxia in kidney and brain | Researchers | Basic research |
Strict anaerobic Staphylococcus saccharolyticus isolates recovered from contaminated platelet concentrates fail to multiply during platelet storage | Ali H, Rood IG, de Korte D, Ramirez-Arcos S | 2012 | Transfusion | View Strict anaerobic Staphylococcus saccharolyticus isolates recovered from contaminated platelet concentrates fail to multiply during platelet storage | Researchers | Basic research |
The cellular pathophysiology of immune thrombocytopenia | Semple JW | 2013 | ISBT Sci Ser | View The cellular pathophysiology of immune thrombocytopenia | Researchers | Basic research |
Thermal reversal of polyvalent choline phosphate, a multivalent universal biomembrane adhesive | Yu X, Zou Y, Horte S, Janzen J, Kizhakkedathu JN, Brooks DE | 2013 | Biomacromolecules | View Thermal reversal of polyvalent choline phosphate, a multivalent universal biomembrane adhesive | Researchers | Basic research |
Verotoxin A subunit protects lymphocytes and T cell lines against X4 HIV infection in vitro | Shi PL, Binnington B, Sakac D, Katsman Y, Ramkumar S, Gariepy J, Kim M, Branch DR, Lingwood C | 2012 | Toxins (Basel) | View Verotoxin A subunit protects lymphocytes and T cell lines against X4 HIV infection in vitro | Researchers | Basic research |
ResearchUnit: One in a million: Modelling rare blood flow | Blake J, Clarke G | 2019 | Blood.ca website | View ResearchUnit: One in a million: Modelling rare blood flow | Researchers | Clinical research |
Effect of liposome treatment on hemorheology and metabolic profile of human red blood cells during hypothermic storage | Da Silveira Cavalcante L, Acker J, Holovati J | 2018 | Biopreserv Biobank | View Effect of liposome treatment on hemorheology and metabolic profile of human red blood cells during hypothermic storage | Researchers | Basic research |
Reducing red blood cell folate testing: a case study in utilisation management | Ismail O, Chin-Yee I, Gob A, Bhayana V, Rutledge A | 2019 | BMJ Open Quality | View Reducing red blood cell folate testing: a case study in utilisation management | Researchers | Basic research |
Pathophysiology of immune thrombocytopenia | Li J, Sullivan JA, Ni H | 2018 | Curr Opin Hematol | View Pathophysiology of immune thrombocytopenia | Researchers | Other |
Concentré de recherche : Plasma : c'est dans la poche | Sheffield W, Jenkins C | 2018 | Blood.ca website | View Concentré de recherche : Plasma : c'est dans la poche | Researchers | Basic research |
An enzymatic pathway in the human gut microbiome that converts A to universal O type blood | Rahfeld P, Sim L, Moon H, Constantinescu I, Morgan-Lang C, Hallam SJ, Kizhakkedathu JN, Withers SG | 2019 | Nat Microbiol | View An enzymatic pathway in the human gut microbiome that converts A to universal O type blood | Researchers | Basic research |
Is Platelet Desialylation a Novel Biomarker and Therapeutic Target in Immune Thrombocytopenia? | Li J, Sullivan J, Ni H | 2020 | Cell Immunol | View Is Platelet Desialylation a Novel Biomarker and Therapeutic Target in Immune Thrombocytopenia? | Researchers | Basic research |
Population pharmacokinetics of two recombinant human coagulation factor preparations in patients with hemophilia A | Hua BL, Chelle P, Yeung C, Gu J, Zhao YQ, Iorio A | 2019 | Zhonghua Xue Ye Xue Za Zhi | View Population pharmacokinetics of two recombinant human coagulation factor preparations in patients with hemophilia A | Researchers | Clinical research |
Current and Future Perspectives for the Cryopreservation of Cord Blood Stem Cells | Jahan S, Kaushal R, Pasha R, Pineault N | 2021 | Transfus Med Rev | View Current and Future Perspectives for the Cryopreservation of Cord Blood Stem Cells | Researchers | New or improved product or process |
Is the COVID-19 thrombotic catastrophe complement-connected? | Conway EM, Pryzdial ELG | 2020 | J Thromb Haemost | View Is the COVID-19 thrombotic catastrophe complement-connected? | Researchers | Basic research |
Platelet Factor 4 Interactions with Short Heparin Oligomers: Implications for Folding and Assembly | Niu C, Yang Y, Huynh A, Nazy I, Kaltashov IA | 2020 | Biophys J | View Platelet Factor 4 Interactions with Short Heparin Oligomers: Implications for Folding and Assembly | Researchers | Basic research |
SCAR: The high-prevalence antigen 013.008 in the Scianna blood group system | Srivastava K, Albasri J, Alsuhaibani OM, Aljasem HA, Bueno MU, Antonacci T, Branch DR, Denomme GA, Flegel WA | 2021 | Transfusion | View SCAR: The high-prevalence antigen 013.008 in the Scianna blood group system | Researchers | Basic research |
Anti-inflammatory activity of CD44 antibodies in murine immune thrombocytopenia is mediated by Fc? receptor inhibition | Norris PAA, Kaur G, Khan R, Zhu G, Ni H, Lazarus AH | 2021 | Blood | View Anti-inflammatory activity of CD44 antibodies in murine immune thrombocytopenia is mediated by Fc? receptor inhibition | Researchers | Basic research |
An uncertain association between influenza season, recent influenza vaccination campaigns, and unconfirmed repeat reactive syphilis serology assay results in Canadian blood donors | Drews SJ, Bodnar M, Gill B, Carson D, Hawes G, Yi QL, Tran V, Zhou HY, Bigham M, O'Brien SF | 2022 | Transfusion | View An uncertain association between influenza season, recent influenza vaccination campaigns, and unconfirmed repeat reactive syphilis serology assay results in Canadian blood donors | Researchers | Benchmarking and standard setting |
Newer formulations of intravenous iron: a review of their chemistry and key safety aspects – hypersensitivity, hypophosphatemia, and cardiovascular safety | Blumenstein I, Shanbhag S, Langguth P, Kalra PA, Zoller H, Lim W | 2021 | Expert Opin Drug Saf | View Newer formulations of intravenous iron: a review of their chemistry and key safety aspects – hypersensitivity, hypophosphatemia, and cardiovascular safety | Researchers | Basic research |
A Qualitative Comparison of the Abbott SARS-CoV-2 IgG II Quant Assay against Commonly Used Canadian SARS-CoV-2 Enzyme Immunoassays in Blood Donor Retention Specimens, April 2020 to March 2021 | Abe KT, Rathod B, Colwill K, Gingras A-C, Tuite A, Robbins NF, Orjuela G, Jenkins C, Conrod V, Yi Q-L, O’Brien SF, Drews SJ | 2022 | Microbiol Spectr | View A Qualitative Comparison of the Abbott SARS-CoV-2 IgG II Quant Assay against Commonly Used Canadian SARS-CoV-2 Enzyme Immunoassays in Blood Donor Retention Specimens, April 2020 to March 2021 | Researchers | Benchmarking and standard setting |
Blood is a politic of place-making: Blackness, queerness and the construction of the donor | Dryden OH | 2022 | Harriet’s Legacies: Race, Historical Memory, and Futures in Canada | View Blood is a politic of place-making: Blackness, queerness and the construction of the donor | Researchers | MSM research |
Automated closed volume reduction process for apheresis stem cell grafts: From development to clinical implementation | Howell A, Letcher B, Murphy K, Elmoazzen H, Petraszko T, Acker JP, Pineault N, Holovati JL | 2022 | Transfusion | View Automated closed volume reduction process for apheresis stem cell grafts: From development to clinical implementation | Researchers | New or improved product or process |
A data-informed system to manage scarce blood product allocation in a randomized controlled trial of convalescent plasma | Li N, Zeller MP, Shih AW, Heddle NM, St. John M, Bégin P, Callum J, Arnold DM, Akbari-Moghaddam M, Down DG, Jamula E, Devine DV, Tinmouth A | 2022 | Transfusion | View A data-informed system to manage scarce blood product allocation in a randomized controlled trial of convalescent plasma | Researchers | Clinical research |
Current status of rapid bacterial detection methods for platelet components: A 20-year review by the ISBT Transfusion-Transmitted Infectious Diseases Working Party Subgroup on Bacteria | Schmidt M, Ramirez-Arcos S, Stiller L, McDonald C, ISBT Transfusion-Transmitted Infectious Diseases Working Party Subgroup on Bacteria | 2022 | Vox Sang | View Current status of rapid bacterial detection methods for platelet components: A 20-year review by the ISBT Transfusion-Transmitted Infectious Diseases Working Party Subgroup on Bacteria | Researchers | Benchmarking and standard setting |
An official American Thoracic Society/International Society for Heart and Lung Transplantation/Society of Critical Care Medicine/Association of Organ and Procurement Organizations/United Network of Organ Sharing Statement: ethical and policy considerations in organ donation after circulatory determination of death | Gries CJ, White DB, Truog RD, Dubois J, Cosio CC, Dhanani S, Chan KM, Corris P, Dark J, Fulda G, Glazier AK, Higgins R, Love R, Mason DP, Nakagawa TA, Shapiro R, Shemie S, Tracy MF, Travaline JM, Valapour M, West L, Zaas D, Halpern SD, American Thoracic Society Health Policy Committee | 2013 | Am J Respir Crit Care Med | View An official American Thoracic Society/International Society for Heart and Lung Transplantation/Society of Critical Care Medicine/Association of Organ and Procurement Organizations/United Network of Organ Sharing Statement: ethical and policy considerations in organ donation after circulatory determination of death | Researchers | Benchmarking and standard setting |
Attitudes toward Reciprocity Systems for Organ Donation and Allocation for Transplantation | Burkell JA, Chandler JA, Shemie SD | 2013 | J Health Polit Policy Law | View Attitudes toward Reciprocity Systems for Organ Donation and Allocation for Transplantation | Researchers | Other |
Cellular immune dysfunction in immune thrombocytopenia (ITP) | McKenzie CGJ, Guo L, Freedman J, Semple JW | 2013 | Br J Haematol | View Cellular immune dysfunction in immune thrombocytopenia (ITP) | Researchers | Basic research |
CXCR4 transfection of cord blood mesenchymal stromal cells with the use of cationic liposome enhances their migration toward stromal cell-derived factor-1 | Marquez-Curtis LA, Gul-Uludag H, Xu P, Chen J, Janowska-Wieczorek A | 2013 | Cytotherapy | View CXCR4 transfection of cord blood mesenchymal stromal cells with the use of cationic liposome enhances their migration toward stromal cell-derived factor-1 | Researchers | Basic research |
Dicer cleavage by calpain determines platelet microRNA levels and function in diabetes | Elgheznawy A, Shi L, Hu J, Wittig I, Laban H, Pircher J, Mann A, Provost P, Randriamboavonjy V, Fleming I | 2015 | Circ Res | View Dicer cleavage by calpain determines platelet microRNA levels and function in diabetes | Researchers | Basic research |
Further evidence that paroxysmal nocturnal haemoglobinuria is a disorder of defective cell membrane lipid rafts | Ratajczak MZ, Borkowska S, Mierzejewska K, Kucia M, Mendek-Czajkowska E, Suszynska M, Sharma VA, Deptala A, Song W, Platzbecker U, Larratt L, Janowska-Wieczorek A, Maciejewski J, Ratajczak J | 2015 | J Cell Mol Med | View Further evidence that paroxysmal nocturnal haemoglobinuria is a disorder of defective cell membrane lipid rafts | Researchers | Basic research |
Integrin PSI domain has endogenous thiol isomerase function and is a novel target for anti-platelet therapy | Zhu G, Zhang Q, Reddy EC, Carrim N, Chen Y, Xu XR, Xu M, Wang Y, Hou Y, Ma L, Li Y, Rui M, Petruzziello T, Lavalle C, Stratton TW, Lei X, Reheman A, Chen P, Zhu C, Wilkins JA, Hynes RO, Freedman J, Ni H | 2017 | Blood | View Integrin PSI domain has endogenous thiol isomerase function and is a novel target for anti-platelet therapy | Researchers | Basic research |
Leaving nothing to chance: how to randomize a clinical trial | Toltl LJ, Arnold DM | 2012 | Transfusion | View Leaving nothing to chance: how to randomize a clinical trial | Researchers | Other |
Membrane Type-1 Matrix Metalloproteinase Expression in Acute Myeloid Leukemia and Its Upregulation by Tumor Necrosis Factor-? | Marquez-Curtis LA, Shirvaikar N, Turner AR, Mirza I, Surmawala A, Larratt LM, Janowska-Wieczorek A | 2012 | Cancers | View Membrane Type-1 Matrix Metalloproteinase Expression in Acute Myeloid Leukemia and Its Upregulation by Tumor Necrosis Factor-? | Researchers | Basic research |
Monovalent Fc receptor blockade by an anti-Fc? receptor/albumin fusion protein ameliorates murine ITP with abrogated toxicity | Yu X, Menard M, Prechl J, Bhakta V, Sheffield WP, Lazarus AH | 2016 | Blood | View Monovalent Fc receptor blockade by an anti-Fc? receptor/albumin fusion protein ameliorates murine ITP with abrogated toxicity | Researchers | Basic research |
Polymer-mediated immunocamouflage of red blood cells: effects of polymer size on antigenic and immunogenic recognition of allogeneic donor blood cells | Wang D, Kyluik DL, Murad KL, Toyofuku WM, Scott MD | 2011 | Sci China Life Sci | View Polymer-mediated immunocamouflage of red blood cells: effects of polymer size on antigenic and immunogenic recognition of allogeneic donor blood cells | Researchers | Basic research |
Prothrombin complex concentrates reduce blood loss in murine coagulopathy induced by warfarin, but not in that induced by dabigatran etexilate | Lambourne MD, Eltringham-Smith LJ, Gataiance S, Arnold DM, Crowther MA, Sheffield WP | 2012 | J Thromb Haemost | View Prothrombin complex concentrates reduce blood loss in murine coagulopathy induced by warfarin, but not in that induced by dabigatran etexilate | Researchers | Basic research |
Reduced deformability of parasitized red blood cells as a biomarker for anti-malarial drug efficacy | Deng X, Duffy SP, Myrand-Lapierre M-E, Matthews K, Santoso AT, Du Y-L, Ryan KS, Ma H | 2015 | Malar J | View Reduced deformability of parasitized red blood cells as a biomarker for anti-malarial drug efficacy | Researchers | New or improved product or process |
RhoA/ROCK signaling contributes to sex differences in the activation of human platelets | Schubert P, Coupland D, Nombalais M, Walsh G, Devine DV | 2016 | Thromb Res | View RhoA/ROCK signaling contributes to sex differences in the activation of human platelets | Researchers | Basic research |