Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Cardiorespiratory pathogenesis of sickle cell disease in a mouse model Ren J, Ding X, Trudel M, Greer JJ, MacLean JE 2017 Sci Rep View Researchers Basic research
Corticosteroids compared with intravenous immunoglobulin for the treatment of immune thrombocytopenia in pregnancy Sun D, Shehata N, Ye XY, Gregorovich S, De France B, Arnold DM, Shah PS, Malinowski AK 2016 Blood View Researchers Clinical research
Determining the inventory impact of extended shelf life platelets with a network simulation model Blake J 2017 Transfusion View Researchers New or improved product or process
Encapsulation of factor IX-engineered mesenchymal stem cells in fibrinogen-alginate microcapsules enhances their viability and transgene secretion Sayyar B, Dodd M, Wen J, Ma S, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G 2012 J Tissue Eng View Researchers Basic research
Evidence for a novel mechanism independent of myocardial iron in beta-thalassemia cardiac pathogenesis Stoyanova E, Cloutier G, Felfly H, Lemsaddek W, Ah-Son N, Trudel M 2012 PLoS One View Researchers Basic research
Fibronectin-Alginate microcapsules improve cell viability and protein secretion of encapsulated Factor IX-engineered human mesenchymal stromal cells Sayyar B, Dodd M, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G 2014 Artif Cells Nanomed Biotechnol View Researchers Basic research
Immunocamouflage: The biophysical basis of immunoprotection by grafted methoxypoly(ethylene glycol) (mPEG) Le Y, Scott MD 2010 Acta Biomater View Researchers Basic research
Increasing efficiency in protein-protein coupling: subunit-directed acetylation and phase-directed CuAAC ("click coupling") in the formation of hemoglobin bis-tetramers Wang A, Kluger R 2014 Biochemistry View Researchers Basic research
Mitochondrial damage-associated molecular patterns in blood transfusion products Marcoux G, Boilard E 2017 ISBT Sci Ser View Researchers Basic research
Pathogenesis and Therapeutic Mechanisms in Immune Thrombocytopenia (ITP) Zufferey A, Kapur R, Semple J 2017 J Clin Med View Researchers Basic research
Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A2-IIA Duchez AC, Boudreau LH, Naika GS, Bollinger J, Belleannee C, Cloutier N, Laffont B, Mendoza-Villarroel RE, Levesque T, Rollet-Labelle E, Rousseau M, Allaeys I, Tremblay JJ, Poubelle PE, Lambeau G, Pouliot M, Provost P, Soulet D, Gelb MH, Boilard E 2015 PNAS View Researchers Basic research
Quality of red blood cells washed using an automated cell processor with and without irradiation Hansen AL, Turner TR, Yi QL, Acker JP 2014 Transfusion View Researchers New or improved product or process
Reply to: Short-Term versus Long-Term Blood Storage Heddle N 2017 N Engl J Med View Researchers Other
TAILS N-terminomics of human platelets reveals pervasive metalloproteinase-dependent proteolytic processing in storage Prudova A, Serrano K, Eckhard U, Fortelny N, Devine DV, Overall CM 2014 Blood View Researchers Basic research
The fibrinogen but not the Factor VIII content of transfused plasma determines its effectiveness at reducing bleeding in coagulopathic mice Eltringham-Smith LJ, Lei X, Reheman A, Lambourne MD, Pryzdial EL, Ni H, Sheffield WP 2014 Transfusion View Researchers Basic research
The size-dependent efficacy and biocompatibility of hyperbranched polyglycerol in peritoneal dialysis Du C, Mendelson AA, Guan Q, Chapanian R, Chafeeva I, da Roza G, Kizhakkedathu JN 2014 Biomaterials View Researchers Basic research
Using simulation to evaluate a blood supply network in the Canadian maritime provinces Blake J, Hardy M 2013 J Enterp Inf Manag View Researchers New or improved product or process
Concentré de recherche : Une façon nouvelle d'évaluer la qualité des globules rouges Acker J 2018 Blood.ca website View Researchers Clinical research
Fibronectin modulates formation of PF4/heparin complexes and is a potential factor for reducing risk of developing HIT Krauel K, Preuße P, Warkentin TE, Trabhardt C, Brandt S, Jensch I, Mandelkow M, Hammer E, Hammerschmidt S, Greinacher A 2018 Blood View Researchers Basic research
Concentré de recherche : Plasma : c'est dans la poche Sheffield W, Jenkins C 2018 Blood.ca website View Researchers Basic research
An enzymatic pathway in the human gut microbiome that converts A to universal O type blood Rahfeld P, Sim L, Moon H, Constantinescu I, Morgan-Lang C, Hallam SJ, Kizhakkedathu JN, Withers SG 2019 Nat Microbiol View Researchers Basic research
Is Platelet Desialylation a Novel Biomarker and Therapeutic Target in Immune Thrombocytopenia? Li J, Sullivan J, Ni H 2020 Cell Immunol View Researchers Basic research
Population pharmacokinetics of two recombinant human coagulation factor preparations in patients with hemophilia A Hua BL, Chelle P, Yeung C, Gu J, Zhao YQ, Iorio A 2019 Zhonghua Xue Ye Xue Za Zhi View Researchers Clinical research
Current and Future Perspectives for the Cryopreservation of Cord Blood Stem Cells Jahan S, Kaushal R, Pasha R, Pineault N 2021 Transfus Med Rev View Researchers New or improved product or process
Is the COVID-19 thrombotic catastrophe complement-connected? Conway EM, Pryzdial ELG 2020 J Thromb Haemost View Researchers Basic research
Platelet Factor 4 Interactions with Short Heparin Oligomers: Implications for Folding and Assembly Niu C, Yang Y, Huynh A, Nazy I, Kaltashov IA 2020 Biophys J View Researchers Basic research
SCAR: The high-prevalence antigen 013.008 in the Scianna blood group system Srivastava K, Albasri J, Alsuhaibani OM, Aljasem HA, Bueno MU, Antonacci T, Branch DR, Denomme GA, Flegel WA 2021 Transfusion View Researchers Basic research
Anti-inflammatory activity of CD44 antibodies in murine immune thrombocytopenia is mediated by Fc? receptor inhibition Norris PAA, Kaur G, Khan R, Zhu G, Ni H, Lazarus AH 2021 Blood View Researchers Basic research
An uncertain association between influenza season, recent influenza vaccination campaigns, and unconfirmed repeat reactive syphilis serology assay results in Canadian blood donors Drews SJ, Bodnar M, Gill B, Carson D, Hawes G, Yi QL, Tran V, Zhou HY, Bigham M, O'Brien SF 2022 Transfusion View Researchers Benchmarking and standard setting
Newer formulations of intravenous iron: a review of their chemistry and key safety aspects – hypersensitivity, hypophosphatemia, and cardiovascular safety Blumenstein I, Shanbhag S, Langguth P, Kalra PA, Zoller H, Lim W 2021 Expert Opin Drug Saf View Researchers Basic research
A Qualitative Comparison of the Abbott SARS-CoV-2 IgG II Quant Assay against Commonly Used Canadian SARS-CoV-2 Enzyme Immunoassays in Blood Donor Retention Specimens, April 2020 to March 2021 Abe KT, Rathod B, Colwill K, Gingras A-C, Tuite A, Robbins NF, Orjuela G, Jenkins C, Conrod V, Yi Q-L, O’Brien SF, Drews SJ 2022 Microbiol Spectr View Researchers Benchmarking and standard setting
Blood is a politic of place-making: Blackness, queerness and the construction of the donor Dryden OH 2022 Harriet’s Legacies: Race, Historical Memory, and Futures in Canada View Researchers MSM research
Automated closed volume reduction process for apheresis stem cell grafts: From development to clinical implementation Howell A, Letcher B, Murphy K, Elmoazzen H, Petraszko T, Acker JP, Pineault N, Holovati JL 2022 Transfusion View Researchers New or improved product or process
A data-informed system to manage scarce blood product allocation in a randomized controlled trial of convalescent plasma Li N, Zeller MP, Shih AW, Heddle NM, St. John M, Bégin P, Callum J, Arnold DM, Akbari-Moghaddam M, Down DG, Jamula E, Devine DV, Tinmouth A 2022 Transfusion View Researchers Clinical research
Current status of rapid bacterial detection methods for platelet components: A 20-year review by the ISBT Transfusion-Transmitted Infectious Diseases Working Party Subgroup on Bacteria Schmidt M, Ramirez-Arcos S, Stiller L, McDonald C, ISBT Transfusion-Transmitted Infectious Diseases Working Party Subgroup on Bacteria 2022 Vox Sang View Researchers Benchmarking and standard setting
An official American Thoracic Society/International Society for Heart and Lung Transplantation/Society of Critical Care Medicine/Association of Organ and Procurement Organizations/United Network of Organ Sharing Statement: ethical and policy considerations in organ donation after circulatory determination of death Gries CJ, White DB, Truog RD, Dubois J, Cosio CC, Dhanani S, Chan KM, Corris P, Dark J, Fulda G, Glazier AK, Higgins R, Love R, Mason DP, Nakagawa TA, Shapiro R, Shemie S, Tracy MF, Travaline JM, Valapour M, West L, Zaas D, Halpern SD, American Thoracic Society Health Policy Committee 2013 Am J Respir Crit Care Med View Researchers Benchmarking and standard setting
Attitudes toward Reciprocity Systems for Organ Donation and Allocation for Transplantation Burkell JA, Chandler JA, Shemie SD 2013 J Health Polit Policy Law View Researchers Other
Cellular immune dysfunction in immune thrombocytopenia (ITP) McKenzie CGJ, Guo L, Freedman J, Semple JW 2013 Br J Haematol View Researchers Basic research
CXCR4 transfection of cord blood mesenchymal stromal cells with the use of cationic liposome enhances their migration toward stromal cell-derived factor-1 Marquez-Curtis LA, Gul-Uludag H, Xu P, Chen J, Janowska-Wieczorek A 2013 Cytotherapy View Researchers Basic research
Dicer cleavage by calpain determines platelet microRNA levels and function in diabetes Elgheznawy A, Shi L, Hu J, Wittig I, Laban H, Pircher J, Mann A, Provost P, Randriamboavonjy V, Fleming I 2015 Circ Res View Researchers Basic research
Further evidence that paroxysmal nocturnal haemoglobinuria is a disorder of defective cell membrane lipid rafts Ratajczak MZ, Borkowska S, Mierzejewska K, Kucia M, Mendek-Czajkowska E, Suszynska M, Sharma VA, Deptala A, Song W, Platzbecker U, Larratt L, Janowska-Wieczorek A, Maciejewski J, Ratajczak J 2015 J Cell Mol Med View Researchers Basic research
Integrin PSI domain has endogenous thiol isomerase function and is a novel target for anti-platelet therapy Zhu G, Zhang Q, Reddy EC, Carrim N, Chen Y, Xu XR, Xu M, Wang Y, Hou Y, Ma L, Li Y, Rui M, Petruzziello T, Lavalle C, Stratton TW, Lei X, Reheman A, Chen P, Zhu C, Wilkins JA, Hynes RO, Freedman J, Ni H 2017 Blood View Researchers Basic research
Leaving nothing to chance: how to randomize a clinical trial Toltl LJ, Arnold DM 2012 Transfusion View Researchers Other
Membrane Type-1 Matrix Metalloproteinase Expression in Acute Myeloid Leukemia and Its Upregulation by Tumor Necrosis Factor-? Marquez-Curtis LA, Shirvaikar N, Turner AR, Mirza I, Surmawala A, Larratt LM, Janowska-Wieczorek A 2012 Cancers View Researchers Basic research
Monovalent Fc receptor blockade by an anti-Fc? receptor/albumin fusion protein ameliorates murine ITP with abrogated toxicity Yu X, Menard M, Prechl J, Bhakta V, Sheffield WP, Lazarus AH 2016 Blood View Researchers Basic research
Red blood cell antibody induced anemia causes differential degrees of tissue hypoxia in kidney and brain Mistry N, Mazer CD, Sled JG, Lazarus AH, Cahill LS, Solish M, Zhou Y-Q, Romanova N, Hare AG, Doctor A, Fisher JA, Brunt KR, Simpson JA, Hare GMT 2018 Am J Physiol Regul Integr Comp Physiol View Researchers Basic research
Strict anaerobic Staphylococcus saccharolyticus isolates recovered from contaminated platelet concentrates fail to multiply during platelet storage Ali H, Rood IG, de Korte D, Ramirez-Arcos S 2012 Transfusion View Researchers Basic research
The cellular pathophysiology of immune thrombocytopenia Semple JW 2013 ISBT Sci Ser View Researchers Basic research
Thermal reversal of polyvalent choline phosphate, a multivalent universal biomembrane adhesive Yu X, Zou Y, Horte S, Janzen J, Kizhakkedathu JN, Brooks DE 2013 Biomacromolecules View Researchers Basic research
Verotoxin A subunit protects lymphocytes and T cell lines against X4 HIV infection in vitro Shi PL, Binnington B, Sakac D, Katsman Y, Ramkumar S, Gariepy J, Kim M, Branch DR, Lingwood C 2012 Toxins (Basel) View Researchers Basic research