Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Proteomic analysis of red blood cells from donors exhibiting high hemolysis demonstrates a reduction in membrane?associated proteins involved in the oxidative response Chen D, Schubert P, Devine DV 2017 Transfusion View Researchers Basic research
Red cell transfusion-associated hemolysis in cardiac surgery: an observational cohort study Karkouti K, Callum J, Acker JP, Yip P, Rao V 2017 Anesth Analg View Researchers Clinical research
Reversible hemostatic properties of sulfabetaine/quaternary ammonium modified hyperbranched polyglycerol Wen J, Weinhart M, Lai B, Kizhakkedathu J, Brooks DE 2016 Biomaterials View Researchers Basic research
The effect of timing of gamma-irradiation on hemolysis and potassium release in leukoreduced red cell concentrates stored in SAGM Serrano K, Chen D, Hansen AL, Levin E, Turner TR, Kurach JDR, Acker JP, Devine DV 2014 Vox Sang View Researchers New or improved product or process
Thymic retention of CD4+CD25+FoxP3+ T regulatory cells is associated with their peripheral deficiency and thrombocytopenia in a murine model of immune thrombocytopenia Aslam R, Hu Y, Gebremeskel S, Segel GB, Speck ER, Guo L, Kim M, Ni H, Freedman J, Semple JW 2012 Blood View Researchers Basic research
Two-stage, in silico deconvolution of the lymphocyte compartment of the peripheral whole blood transcriptome in the context of acute kidney allograft rejection Shannon CP, Balshaw R, Ng RT, Wilson-McManus JE, Keown P, McMaster R, McManus BM, Landsberg D, Isbel NM, Knoll G, Tebbutt SJ 2014 PLoS One View Researchers Basic research
Improving Time to Antibiotics for Pediatric Oncology Patients With Fever and Suspected Neutropenia by Applying Lean Principles Geerlinks AV, Digout C, Bernstein M, Chan A, MacPhee S, Pambrun C, Gallant G, Wyatt L, Fernandez CV, Price VE 2018 Pediatric Emergency Care View Researchers New or improved product or process
The effect of tantalum incorporation on the physical and chemical properties of ternary silicon–calcium–phosphorous mesoporous bioactive glasses Mendonca A, Rahman MS, Alhalawani A, Rodriguez O, Gallant RC, Ni H, Clarkin OM, Towler MR 2019 J Biomed Mater Res B Appl Biomater View Researchers Basic research
Trends and outcomes in multicomponent blood transfusion: an 11-year cohort study of a large multisite academic center Perelman I, Saidenberg E, Tinmouth A, Fergusson D 2019 Transfusion View Researchers Clinical research
rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and Fc?Rs Spirig R, Campbell IK, Koernig S, Chen C-G, Lewis BJB, Butcher R, Muir I, Taylor S, Chia J, Leong D, Simmonds J, Scotney P, Schmidt P, Fabri L, Hofmann A, Jordi M, Spycher MO, Cattepoel S, Brasseit J, Panousis C, Rowe T, Branch DR, Baz Morelli A, Kaesermann F, Zuercher AW 2018 J Immunol View Researchers Basic research
Acquired factor XIII deficiency: A review Yan MTS, Rydz N, Goodyear D, Sholzberg M 2018 Transfus Apher Sci View Researchers Other
Comparative pharmacokinetics of two extended half-life FVIII concentrates (Eloctate and Adynovate) in adolescents with hemophilia A: Is there a difference? Carcao MD, Chelle P, Clarke E, Kim L, Tiseo L, Morfini M, Hossain T, Rand ML, Brown C, Edginton AN, Lillicrap D, Iorio A, Blanchette VS 2019 J Thromb Haemost View Researchers Clinical research
Barriers and enablers to source plasma donation by gay, bisexual and other men who have sex with men under revised eligibility criteria: protocol for a multiple stakeholder feasibility study Vesnaver E, Goldman M, O’Brien S, MacPherson P, Butler-Foster T, Lapierre D, Otis J, Devine DV, Germain M, Rosser A, MacDonagh R, Randall T, Osbourne-Sorrell W, Clement-Thorne B, Al-Bakri TB, Rubini KA, Hill NE, Presseau J 2020 Health Res Policy Syst View Researchers MSM research
The Missing Pieces to the Cold-Stored Platelet Puzzle Zhao H, Devine DV 2022 Int J Mol Sci View Researchers Basic research
Use of CRISPR/Cas9 gene editing to improve chimeric antigen-receptor T cell therapy: A systematic review and meta-analysis of preclinical studies Maganti HB, Kirkham AM, Bailey AJM, Shorr R, Kekre N, Pineault N, Allan DS 2022 Cytotherapy View Researchers Clinical research
The international experience of bacterial screen testing of platelet components with automated microbial detection systems: An update Kamel H, Ramirez-Arcos S, McDonald C, ISBT Transfusion-Transmitted Infectious Disease Bacterial Working Party Bacterial Subgroup 2022 Vox Sang View Researchers Benchmarking and standard setting
Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis Almizraq RJ, Frias Boligan K, Lewis BJB, Cen S, Whetstone H, Spirig R, Käsermann F, Campbell IK, von Gunten S, Branch DR 2023 Pharmacology View Researchers Basic research
Assessment of the soluble proteins HMGB1, CD40L and CD62P during various platelet preparation processes and the storage of platelet concentrates: The BEST collaborative study Cognasse F, Hamzeh Cognasse H, Eyraud MA, Prier A, Arthaud CA, Tiberghien P, Begue S, de Korte D, Gouwerok E, Greinacher A, Aurich K, Noorman F, Dumont L, Kelly K, Cloutier M, Bazin R, Cardigan R, Huish S, Smethurst P, Devine D, Schubert P, Johnson L, Marks DC, Biomedical Excellence for Safer Transfusion Collaborative 2023 Transfusion View Researchers Basic research
HIV incidence and related risks among gay, bisexual, and other men who have sex with men in Montreal, Toronto, and Vancouver: Informing blood donor selection criteria in Canada Lambert G, Cox J, Fourmigue A, Dvorakova M, Apelian H, Moodie EEM, Grace D, Skakoon-Sparling S, Moore DM, Lachowsky N, Jollimore J, Lal A, Parlette A, Hart TA 2022 Transfusion View Researchers MSM research
Multicenter evaluation of the IL-3-pSTAT5 assay to assess the potency of cryopreserved stem cells from cord blood units: The BEST Collaborative study Trépanier P, Fournier D, Simard C, Fontaine MJ, Stroncek D, Takanashi M, McKenna D, Schwartz J, Tanhehco YC, Reems J-A, Torrents S, Kogler G, Liedtke S, Giroux M, Holovati JL, Louis I, Prasath A, Pineault N, Bazin R, The Biomedical Excellence for Safer Transfusion Collaborative 2022 Transfusion View Researchers Benchmarking and standard setting
A lab-on-chip for malaria diagnosis and surveillance Taylor BJ, Howell A, Martin KA, Manage DP, Gordy W, Campbell SD, Lam S, Jin A, Polley SD, Samuel RA, Atrazhev A, Stickel AJ, Birungi J, Mbonye AK, Pilarski LM, Acker JP, Yanow SK 2014 Malar J View Researchers Basic research
Applications of Liposomes in Biopreservation Da Silveira Cavalcante L, Holovati J, Acker J 2016 Multiscale technologies for cryomedicine: implementation from nano to macroscale View Researchers Basic research
Biomonitoring of Arsenic in Urine and Saliva of Children Playing on Playgrounds Constructed from Chromated Copper Arsenate-Treated Wood Lew K, Acker JP, Gabos S, Le XC 2010 Environ Sci Technol View Researchers Other
Carbohydrate-based ice recrystallization inhibitors increase infectivity and thermostability of viral vectors Ghobadloo SM, Balcerzak AK, Gargaun A, Muharemagic D, Mironov GG, Capicciotti CJ, Briard JG, Ben RN, Berezovski MV 2014 Sci Rep View Researchers Basic research
Emerging Role for Use of Liposomes in the Biopreservation of Red Blood Cells Holovati JL, Acker JP 2011 Transfus Med Hemother View Researchers Basic research
Fibronectin: extra domain brings extra risk? Wang Y, Ni H 2015 Blood View Researchers Other
Immunocamouflage of latex surfaces by grafted methoxypoly(ethylene glycol) (mPEG): proteomic analysis of plasma protein adsorption Le Y, Li L, Wang D, Scott MD 2012 Sci China Life Sci View Researchers Basic research
Incorporation of albumin fusion proteins into fibrin clots in vitro and in vivo: comparison of different fusion motifs recognized by factor XIIIa Sheffield WP, Eltringham-Smith LJ 2011 BMC Biotechnol View Researchers Basic research
Manufacturing method affects mitochondrial DNA release and extracellular vesicle composition in stored red blood cells Bakkour S, Acker JP, Chafets DM, Inglis HC, Norris PJ, Lee TH, Busch MP 2016 Vox Sang View Researchers Basic research
Mitochondria and membrane cryoinjury in micropatterned cells: Effects of cell-cell interactions Tchir J, Acker JP 2010 Cryobiology View Researchers Basic research
Platelet immunology in China: research and clinical applications Wu G, Zhou Y, Li L, Zhong Z, Li H, Li H, Yu M, Shen W, Ni H 2017 Transfus Med Rev View Researchers Clinical research
Renin-Angiotensin System Blockade and Long-term Clinical Outcomes in Kidney Transplant Recipients: A Meta-analysis of Randomized Controlled Trials Hiremath S, Fergusson DA, Fergusson N, Bennett A, Knoll GA 2017 Am J Kidney Dis View Researchers Clinical research
Solving the dilemma of prevention of red cell alloimmunization Branch DR 2012 Immunotherapy View Researchers Other
The Fanconi anemia pathway has a dual function in Dickkopf-1 transcriptional repression Huard CC, Tremblay CS, Magron A, Levesque G, Carreau M 2014 PNAS View Researchers Basic research
The role of inflammation in intravenous immune globulin-mediated hemolysis Pendergrast J, Willie-Ramharack K, Sampson L, Laroche V, Branch DR 2015 Transfusion View Researchers Clinical research
Transfusion of fresher vs older red blood cells in hospitalized patients: a systematic review and meta-analysis Alexander PE, Barty R, Fei Y, Vandvik PO, Pai M, Siemieniuk RA, Heddle NM, Blumberg N, McLeod SL, Liu J, Eikelboom JW, Guyatt GH 2016 Blood View Researchers Clinical research
ResearchUnit: A different way to look at red blood cell quality Acker J 2018 Blood.ca website View Researchers Clinical research
Characterization of platelet factor 4 amino acids that bind pathogenic antibodies in heparin-induced thrombocytopenia Huynh A, Arnold DM, Kelton JG, Smith JW, Horsewood P, Clare R, Guarné A, Nazy I 2018 J Thromb Haemost View Researchers Basic research
IVIg and LPS Co-stimulation Induces IL-10 Production by Human Monocytes, Which Is Compromised by an FcgRIIA Disease-Associated Gene Variant Kozicky LK, Menzies SC, Zhao ZY, Vira T, Harnden K, Safari K, Del Bel KL, Turvey SE, Sly LM 2018 Front Immunol View Researchers Basic research
What's in a name? Patient registration errors and their threat to transfusion safety Ning S, Yan MTS, Downie H, Callum J 2018 Transfusion View Researchers New or improved product or process
Raman spectroscopy of stored red blood cell concentrate within sealed transfusion blood bags Vardaki MZ, Atkins CG, Schulze HG, Devine DV, Serrano K, Blades MW, Turner RFB 2018 Analyst View Researchers New or improved product or process
Defocused Spatially Offset Raman Spectroscopy in Media of Different Optical Properties for Biomedical Applications Using a Commercial Spatially Offset Raman Spectroscopy Device Vardaki MZ, Devine DV, Serrano K, Simantiris N, Blades MW, Piret JM, Turner RFB 2020 Appl Spectrosc View Researchers New or improved product or process
IgG3 anti-Kell allotypic variation results in differential antigen binding and phagocytosis Cen SY, Holton MB, Binnington B, Denomme GA, Howie HL, Lebedev JN, Zimring JC, Branch DR 2020 Transfusion View Researchers Basic research
Not all red cell concentrate units are equivalent: international survey of processing and in vitro quality data Shih AW, Apelseth TO, Cardigan R, Marks DC, Bégué S, Greinacher A, de Korte D, Seltsam A, Shaz BH, Wikman A, Barty RL, Heddle NM, Acker JP, The QMiP Investigators on behalf of the Biomedical Excellence for Safer Transfusion Collaborative 2019 Vox Sang View Researchers Benchmarking and standard setting
Canada's MSM Research Program - producing and mobilizing knowledge Chargé S, Haw J 2020 Transfusion Today Researchers MSM research
Emerging use of machine learning and advanced technologies to assess red cell quality Sebastian JA, Kolios MC, Acker JP 2020 Transfus Apher Sci View Researchers New or improved product or process
Objective assessment of stored blood quality by deep learning Doan M, Sebastian JA, Caicedo JC, Siegert S, Roch A, Turner TR, Mykhailova O, Pinto RN, McQuin C, Goodman A, Parsons MJ, Wolkenhauer O, Hennig H, Singh S, Wilson A, Acker JP, Rees P, Kolios MC, Carpenter AE 2020 PLoS Pathog View Researchers New or improved product or process
Research Unit: Machine learning throws away the buckets to better understand red blood cell quality Acker JP 2020 Blood.ca website View Researchers Basic research
Transfusion septic reactions involving platelet concentrates contaminated with Citrobacter koseri Ramirez-Arcos S 2020 Ann Blood View Researchers Clinical research
High sub-zero organ preservation: A paradigm of nature-inspired strategies William N, Acker JP 2021 Cryobiology View Researchers Basic research