Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Phospholipidomics reveals differences in glycerophosphoserine profiles of hypothermically stored red blood cells and microvesicles Bicalho B, Holovati JL, Acker JP 2013 Biochim Biophys Acta View Researchers Basic research
The complete N-terminal extension of heparin cofactor II is required for maximal effectiveness as a thrombin exosite 1 ligand Boyle AJ, Roddick LA, Bhakta V, Lambourne MD, Junop MS, Liaw PC, Weitz JI, Sheffield WP 2013 BMC Biochem View Researchers Basic research
Alloimmunization of patients by blood units harboring distinct DEL variants St-Louis M, Lebrun A, Goldman M, Lavoie M 2013 Immunohematology View Health care providers Clinical research
Fc-independent phagocytosis: Implications for IVIG and other therapies in immune-mediated thrombocytopenia Li J, van der Wal DE, Zhu L, Vadasz B, Simpson EK, Li C, Webster ML, Zhu G, Lang S, Chen P, Zeng Q, Ni H 2013 Cardiovasc Hematol Disord Drug Targets View Researchers Other
Identifying D-positive donors using a second automated testing platform Goldman M, Resz I, Cote J, Ochoa G, Angus N 2013 Immunohematology View Blood operators New or improved product or process
Riboflavin and ultraviolet light treatment of platelets triggers p38MAPK signaling: inhibition significantly improves in vitro platelet quality after pathogen reduction treatment Schubert P, Coupland D, Culibrk B, Goodrich RP, Devine DV 2013 Transfusion View Researchers Basic research
CD4+ T-cells are unable to express the HIV natural resistance factor globotriosylceramide Kim M, Binnington B, Sakac D, Lingwood CA, Branch DR 2013 AIDS View Researchers Basic research
Developing highly active small molecule ice recrystallization inhibitors based upon C-linked antifreeze glycoprotein analogues Trant JF, Briggs RA, Capicciotti C, Ben RN 2013 RSC Adv View Researchers Basic research
ResearchUnit: Should patients receive HLA-selected platelets? Shehata N 2013 Blood.ca website View Other Other
Utilization of frozen plasma in Ontario: a province wide audit reveals a high rate of inappropriate transfusions Tinmouth A, Thompson T, Arnold DM, Callum JL, Gagliardi K, Lauzon D, Owens W, Pinkerton P 2013 Transfusion View Health care providers Benchmarking and standard setting
Progressive development of polycystic kidney disease in the mouse model expressing Pkd1 extracellular domain Kurbegovic A, Trudel M 2013 Hum Mol Genet View Researchers Basic research
ResearchUnit: Doubling the 30-minute rule without compromising Red Blood Cells quality and safety. Ramirez-Arcos S 2013 Blood.ca website View Other Other
Thrombocytopenia in the critically ill Shehata N, Fontes ML 2013 Can J Anaesth View Researchers Other
Allowing blood donation from men who had sex with men more than 5 years ago: a model to evaluate the impact on transfusion safety in Canada Germain M, Robillard P, Delage G, Goldman M 2013 Vox Sang View Blood operators New or improved product or process
Design of long circulating nontoxic dendritic polymers for the removal of iron in vivo Imran ul-haq M, Hamilton JL, Lai BF, Shenoi RA, Horte S, Constantinescu I, Leitch HA, Kizhakkedathu JN 2013 ACS Nano View Researchers Basic research
Efficacy of HLA-matched platelet transfusions for patients with hypoproliferative thrombocytopenia: a systematic review Pavenski K, Rebulla P, Duquesnoy R, Saw CL, Slichter SJ, Tanael S, Shehata N, International Collaboration for Guideline Development Implementation and Evaluation for Transfusion Therapies (ICTMG) Collaborators 2013 Transfusion View Researchers Clinical research
N-ethylmaleimide activates a Cl(-)-independent component of K(+) flux in mouse erythrocytes Shmukler BE, Hsu A, Alves J, Trudel M, Rust MB, Hubner CA, Rivera A, Alper SL 2013 Blood Cells Mol Dis View Researchers Basic research
Posttransplant monitoring of de novo human leukocyte antigen donor-specific antibodies in kidney transplantation Wiebe C, Nickerson P 2013 Curr Opin Organ Transplant View Health care providers Clinical research
Sustained remissions of immune thrombocytopenia associated with the use of thrombopoietin receptor agonists Ghadaki B, Nazi I, Kelton JG, Arnold DM 2013 Transfusion View Health care providers Clinical research
Unraveling the IVIG mystique Branch DR 2013 Transfusion View Researchers Other
What should men living with severe haemophilia need to know? The perspectives of Canadian haemophilia health care providers Lane S, Arnold E, Webert KE, Chan A, Walker I, Heddle NM 2013 Haemophilia View Health care providers Other
An enclosed in-gel PCR amplification cassette with multi-target, multi-sample detection for platform molecular diagnostics Manage DP, Lauzon J, Atrazev A, Chavali R, Samuel RA, Chan B, Morrissey YC, Gordy W, Edwards AL, Larison K, Yanow SK, Acker JP, Zahariadis G, Pilarski LM 2013 Lab Chip View Health care providers New or improved product or process
CD44 antibodies and immune thrombocytopenia in the amelioration of murine inflammatory arthritis Mott PJ, Lazarus AH 2013 PLoS One View Researchers Basic research
Advancing risk assessment for emerging infectious diseases for blood and blood products: proceedings of a public workshop Gallagher LM, Ganz PR, Yang H, Kessler DA, O'Brien SF, Custer BS, Busch MP, Dodd RY, Stramer SL, Walderhaug MO, Forshee RA, Williams AE, Epstein JS, Anderson SA 2013 Transfusion View Blood operators Other
Blood component transfusion in critically ill patients McIntyre L, Tinmouth AT, Fergusson DA 2013 Curr Opin Crit Care View Health care providers Clinical research
E-selectin mediated adhesion and migration of endothelial colony forming cells is enhanced by SDF-1alpha/CXCR4 Sun J, Li Y, Graziani GM, Filion L, Allan DS 2013 PLoS One View Researchers Basic research
Alpha-1 Acid Glycoprotein Reduces Hepatic Leukocyte Recruitment in Murine Models of Either Early Endotoxemia or Early Sepsis McCurdy TR, Patrick AL, Eltringham-Smith LJ, Bhakta V, Sheffield WP, Fox-Robichaud AE 2014 Microcirculation View Researchers Basic research
Design, implementation, and evaluation of a knowledge translation intervention to increase organ donation after cardiocirculatory death in Canada: a study protocol Squires JE, Grimshaw JM, Taljaard M, Linklater S, Chasse M, Shemie SD, Knoll GA 2014 Implement Sci View Researchers Other
Migration, proliferation and differentiation of cord blood mesenchymal stromal cells treated with histone deacetylase inhibitor valproic acid Marquez-Curtis LA, Qiu Y, Xu A, Janowska-Wieczorek A 2014 Stem Cells Int View Researchers Basic research
ResearchUnit: Pathogen Inactivation for Safer Blood Transfusion: What are the Limitations? Schubert P 2014 Blood.ca website View Other Other
An epidemiologic cohort study reviewing the practice of blood product transfusions among a population of pediatric oncology patients Lieberman L, Liu Y, Portwine C, Barty RL, Heddle NM 2014 Transfusion View Health care providers Clinical research
Enhanced Pathogenicity of biofilm-negative Staphylococcus epidermidis isolated from platelet preparations Hodgson SD, Greco-Stewart V, Jimenez CS, Sifri CD, Brassinga AKC, Ramirez-Arcos S 2014 Transfusion View Blood operators Basic research
Stability of relevant plasma protein activities in cryosupernatant plasma units during refrigerated storage for up to 5 days postthaw Bhakta V, Jenkins C, Ramirez-Arcos S, Sheffield WP 2014 Transfusion View Blood operators New or improved product or process
Autologous stem cell transplantation for stiff person syndrome: two cases from the Ottawa blood and marrow transplant program Sanders S, Bredeson C, Pringle CE, Martin L, Allan D, Bence-Bruckler I, Hamelin L, Hopkins HS, Sabloff M, Sheppard D, Tay J, Huebsch L, Atkins HL 2014 JAMA Neurol View Health care providers Clinical research
Levofloxacin for BK virus prophylaxis following kidney transplantation: a randomized clinical trial Knoll GA, Humar A, Fergusson D, Johnston O, House AA, Kim SJ, Ramsay T, Chasse M, Pang X, Zaltzman J, Cockfield S, Cantarovich M, Karpinski M, Lebel L, Gill JS 2014 JAMA View Health care providers Clinical research
Osmotic parameters of red blood cells from umbilical cord blood Zhurova M, McGann LE, Acker JP 2014 Cryobiology View Researchers Basic research
Physician registration for deceased organ donation Li AH, Dixon S, Prakash V, Kim SJ, Knoll GA, Lam NN, Garg AX 2014 JAMA View Health care providers Other
A fresh look at measuring quality in blood components Devine DV, Chen D 2014 ISBT Sci Ser View Blood operators Other
Alpha-1 proteinase inhibitor M358R reduces thrombin generation when displayed on the surface of cells expressing tissue factor Gierczak RF, Pepler L, Bhagirath V, Liaw PC, Sheffield WP 2014 Thromb Res View Researchers Basic research
Designing ice recrystallization inhibitors: from antifreeze (glyco)proteins to small molecules Balcerzak AK, Capicciotti CJ, Briard JG, Ben RN 2014 RSC Adv View Researchers Basic research
Iron deficiency in Canadian blood donors Goldman M, Uzicanin S, Scalia V, O'Brien SF 2014 Transfusion View Health care providers Clinical research
Regulatory decisions pertaining to aprotinin may be putting patients at risk Hebert PC, Fergusson DA, Hutton B, Mazer CD, Fremes S, Blajchman M, MacAdams C, Wells G, Robblee J, Bussieres J, Teoh K 2014 CMAJ View Regulators Other
ResearchUnit: Plasma Fibronectin: Keeping the Delicate Balance between Bleeding and Clotting Ni H 2014 Blood.ca website View Other Other
Acute hemolysis after intravenous immunoglobulin amid host factors of ABO-mismatched bone marrow transplantation, inflammation, and activated mononuclear phagocytes Michelis FV, Branch DR, Scovell I, Bloch E, Pendergrast J, Lipton JH, Cserti-Gazdewich CM 2014 Transfusion View Health care providers Clinical research
CD44 antibody-mediated amelioration of murine immune thrombocytopenia (ITP): mouse background determines the effect of FcgammaRIIb genetic disruption Crow AR, Amash A, Lazarus AH 2014 Transfusion View Researchers Basic research
Enhancement of biological reactions on cell surfaces via macromolecular crowding Chapanian R, Kwan DH, Constantinescu I, Shaikh FA, Rossi NA, Withers SG, Kizhakkedathu JN 2014 Nat Commun View Researchers Basic research
Novel treatments for immune thrombocytopenia Shih A, Nazi I, Kelton JG, Arnold DM 2014 Presse Med View Health care providers Clinical research
Prevention of Thrombogenesis from Whole Human Blood on Plastic Polymer by Ultrathin Monoethylene Glycol Silane Adlayer Fedorov K, Blaszykowski C, Sheikh S, Reheman A, Romaschin A, Ni H, Thompson M 2014 Langmuir View Researchers Basic research
A 13-question approach to resolving serological discrepancies in the transfusion medicine laboratory Yudin J, Heddle NM 2014 Lab Med View Health care providers Clinical research
Changing trends in blood transfusion: an analysis of 244,013 hospitalizations Shehata N, Forster A, Lawrence N, Rothwell DM, Fergusson D, Tinmouth A, Wilson K 2014 Transfusion View Health care providers Clinical research