Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Sort descending Purpose
A Survey of Patient Experience in CML: American and Canadian Perspectives Hillis C, Flynn KE, Goldman EH, Moreira-Lucas TS, Visentini J, Dorman S, Ballinger R, Byrnes HF, De Palma A, Barbier V, Machado L, Atallah E 2023 Patient Prefer Adherence Researchers Clinical research
Database-driven research and big data analytic approaches in transfusion medicine Ning S, Li N, Barty R, Arnold D, Heddle NM 2022 Transfusion Researchers Clinical research
A positive blood culture is associated with a lower haemoglobin increment in hospitalized patients after red blood cell transfusion Qadri SM, Liu Y, Barty RL, Heddle NM, Sheffield WP 2022 Vox Sang Researchers Clinical research
Concentré de recherche: Évaluation de la sécurité des pompes à perfusion pour les transfusions de globules rouges Wolfe A 2022 Blood.ca website Researchers Benchmarking and standard setting
Activated NK cells cause placental dysfunction and miscarriages in fetal alloimmune thrombocytopenia Yougbare I, Tai WS, Zdravic D, Oswald BE, Lang S, Zhu G, Leong-Poi H, Qu D, Yu L, Dunk C, Zhang J, Sled JG, Lye SJ, Brkic J, Peng C, Hoglund P, Croy BA, Adamson SL, Wen XY, Stewart DJ, Freedman J, Ni H 2017 Nat Commun Researchers Basic research
Assessing the influence of component processing and donor characteristics on quality of red cell concentrates using quality control data Jordan A, Chen D, Yi QL, Kanias T, Gladwin MT, Acker JP 2016 Vox Sang Researchers Basic research
CD44 antibodies and immune thrombocytopenia in the amelioration of murine inflammatory arthritis Mott PJ, Lazarus AH 2013 PLoS One Researchers Basic research
C-reactive protein enhances murine antibody-mediated transfusion-related acute lung injury Kapur R, Kim M, Shanmugabhavananthan S, Liu J, Li Y, Semple JW 2015 Blood Researchers Basic research
Development and testing of a stepwise thaw and dilute protocol for cryopreserved umbilical cord blood units Pasha R, Elmoazzen H, Pineault N 2017 Transfusion Researchers New or improved product or process
Enhanced Nitrite Reductase Activity and Its Correlation with Oxygen Affinity in Hemoglobin Bis-Tetramers Wang A, Kluger R 2016 Biochemistry Researchers Basic research
Fluorous Analogue of Chloramine-T: Preparation, X-ray Structure Determination, and Use as an Oxidant for Radioiodination and s-Tetrazine Synthesis Dzandzi JPK, Beckford Vera DR, Genady AR, Albu SA, Eltringham-Smith LJ, Capretta A, Sheffield WP, Valliant JF 2015 J Org Chem Researchers Basic research
Herpesviruses enhance fibrin clot lysis Gershom ES, Vanden Hoek AL, Meixner SC, Sutherland MR, Pryzdial EL 2012 Thromb Haemost Researchers Basic research
Immunoglobulin G Fc glycans are not essential for antibody-mediated immune suppression to murine erythrocytes Marjoram D, Cruz-Leal Y, Bernardo L, Le NPL, Crispin M, Yu X, Uchikawa M, Lazarus AH 2017 Blood Researchers Basic research
In-Gel Technology for PCR Genotyping and Pathogen Detection Atrazhev A, Manage DP, Stickel AJ, Crabtree HJ, Pilarski LM, Acker JP 2010 Anal Chem Researchers New or improved product or process
Kruppel-like factor 1 (KLF1), KLF2, and Myc control a regulatory network essential for embryonic erythropoiesis Pang CJ, Lemsaddek W, Alhashem YN, Bondzi C, Redmond LC, Ah-Son N, Dumur CI, Archer KJ, Haar JL, Lloyd JA, Trudel M 2012 Mol Cell Biol Researchers Basic research
Novel evidence that pituitary gonadotropins directly stimulate human leukemic cells-studies of myeloid cell lines and primary patient AML and CML cells Abdelbaset-Ismail A, Borkowska S, Janowska-Wieczorek A, Tonn T, Rodriguez C, Moniuszko M, Bolkun L, Koloczko J, Eljaszewicz A, Ratajczak J, Ratajczak MZ, Kucia M 2015 Oncotarget Researchers Basic research
Peculiarities of studying the effects of pathogen reduction technologies on platelets Osman A, Hitzler WE, Provost P 2016 Proteomics Clin Appl Researchers Basic research
Prevention of hemolytic disease of the fetus and newborn: what have we learned from animal models? Cruz-Leal Y, Marjoram D, Lazarus AH 2017 Curr Opin Hematol Researchers Basic research
Raman spectroscopy as a novel tool for monitoring biochemical changes and inter-donor variability in stored red blood cell units Atkins CG, Buckley K, Chen D, Schulze HG, Devine DV, Blades MW, Turner RFB 2016 Analyst Researchers New or improved product or process
Targeting FcRs to treat antibody-dependent autoimmunity Yu X, Lazarus AH 2016 Autoimmun Rev Researchers Other
The impact of perioperative red blood cell transfusions in patients undergoing liver resection: a systematic review Bennett S, Baker LK, Martel G, Shorr R, Pawlik TM, Tinmouth A, McIsaac DI, Hébert PC, Karanicolas PJ, McIntyre L, Turgeon AF, Barkun J, Fergusson D 2017 HPB Researchers Clinical research
The transcription factor Miz-1 is required for embryonic and stress-induced erythropoiesis but dispensable for adult erythropoiesis Kosan C, Rashkovan M, Ross J, Schaffer AM, Saba I, Lemsaddek W, Trudel M, Moroy T 2014 Am J Blood Res Researchers Basic research
Transfusion requirements in cardiac surgery III (TRICS III): study design of a randomized controlled trial Shehata N, Whitlock R, Fergusson DA, Thorpe KE, MacAdams C, Grocott HP, Rubens F, Fremes S, Lellouche F, Bagshaw S, Royse A, Rosseel PM, Hare G, Medicis E, Hudson C, Belley-Cote E, Bainbridge D, Kent B, Shaw A, Byrne K, Syed S, Royse CF, McGuiness S, Hall J, Mazer CD 2018 J Cardiothorac Vasc Anesth Researchers Clinical research
Antimicrobial peptides: an effective approach to prevent bacterial biofilm formation in platelet concentrates Alabdullatif M, Atreya CD, Ramirez-Arcos S 2018 Transfusion Researchers New or improved product or process
Biological mechanisms implicated in adverse outcomes of sex mismatched transfusions Alshalani A, Li W, Juffermans NP, Seghatchian J, Acker JP 2019 Transfus Apher Sci Researchers Basic research
Improved in vitro quality of stored red blood cells upon oxygen reduction prior to riboflavin/UV light treatment of whole blood Schubert P, Culibrk B, Chen D, Serrano K, Levin E, Chen Z, Zoescher P, Goodrich RP, Yoshida T, Devine DV 2019 Transfusion Researchers New or improved product or process
Pertussis vaccine effectiveness in a frequency matched population-based case-control Canadian Immunization Research Network study in Ontario, Canada 2009–2015 Crowcroft NS, Schwartz KL, Chen C, Johnson C, Li Y, Marchand-Austin A, Bolotin S, Jamieson FB, Drews SJ, Russell ML, Svenson LW, Simmonds K, Mahmud SM, Kwong JC 2019 Vaccine Researchers Clinical research
ABO blood group and COVID-19: a review on behalf of the ISBT COVID-19 working group Goel R, Bloch EM, Pirenne F, Al-Riyami AZ, Crowe E, Dau L, Land K, Townsend M, Jecko T, Rahimi-Levene N, Patidar G, Josephson CD, Arora S, Vermeulen M, Vrielink H, Montemayor C, Oreh A, Hindawi S, van den Berg K, Serrano K, So – Osman C, Wood E, Devine DV, Spitalnik SL, the ISBT COVID-19 Working Group 2021 Vox Sang Researchers Clinical research
COVID-19 Case-Age Distribution: Correction for Differential Testing by Age Fisman D, Greer A, Hillmer M, O'Brien S, Drews SJ, Tuite A 2020 medRxiv Researchers Clinical research
DNA Mediated Blood Coagulation: Extracellular DNA Accelerates Fibrinogen Polymerization By Thrombin Independent of Contact Pathway Vappala S, Straus S, Pryzdial EL, Conway E, Kizhakkedathu J 2021 Blood Researchers Basic research
Reconstituted cryopreserved platelets synthesize proteins during short-term storage and packaging a defined subset into microvesicles Schubert P, Johnson L, Culibrk B, Chen Z, Tan S, Marks DC, Devine DV 2021 Transfusion Researchers New or improved product or process
Dimethyl sulfoxide-free cryopreservation solutions for hematopoietic stem cell grafts Kaushal R, Jahan S, McGregor C, Pineault N 2022 Cytotherapy Researchers New or improved product or process
A Higher Antibody Response Is Generated With a 6- to 7-Week (vs Standard) Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Dosing Interval Grunau B, Asamoah-Boaheng M, Lavoie PM, Karim ME, Kirkham TL, Demers PA, Barakauskas V, Marquez AC, Jassem AN, O'Brien SF, Drews SJ, Haig S, Cheskes S, Goldfarb DM 2021 Clin Infect Dis Researchers Clinical research
Co-administration of FVIII with IVIG reduces immune response to FVIII in hemophilia A mice Afraz S, Stevic I, Matino D, Wen J, Atkinson H, Chan AKC, Hortelano G 2022 Sci Rep Researchers Clinical research
Thymic stromal lymphopoietin induces platelet mitophagy and promotes thrombosis in Kawasaki disease Fu L, MacKeigan DT, Gong Q, Che D, Xu Y, Pi L, Sun C, Yu H, Chen K, Zhou H, Jiang Z, Wang Z, Zhang L, Cerenzia EG, Ni H, Gu X 2023 Brit J Haem Researchers Clinical research
Blood donor eligibility criteria for medical conditions: A BEST collaborative study Jacquot C, Tiberghien P, van den Hurk K, Ziman A, Shaz B, Apelseth TO, Goldman M, The Biomedical Excellence for Safer Transfusion Collaborative 2022 Vox Sang Researchers Benchmarking and standard setting
SARS-CoV-2 Seroprevalence among Canadian Blood Donors: The Advance of Omicron O’Brien SF, Caffrey N, Yi Q-L, Pambrun C, Drews SJ 2022 Viruses Researchers Clinical research
Prevalence of selected bleeding and thrombotic events in persons with hemophilia versus the general population: A scoping review Shapiro AD, Hardesty BM, Peyvandi F, Iorio A 2023 Res Pract Thromb Haemost Researchers Clinical research
Animal model of fetal and neonatal immune thrombocytopenia: role of neonatal Fc receptor in the pathogenesis and therapy Chen P, Li C, Lang S, Zhu G, Reheman A, Spring CM, Freedman J, Ni H 2010 Blood Researchers Basic research
Comparison of detection methods for cell surface globotriaosylceramide Kim M, Binnington B, Sakac D, Fernandes KR, Shi SP, Lingwood CA, Branch DR 2011 J Immunol Methods Researchers Basic research
Defining Significant Events for Neonatal and Pediatric Transport: Results of a Combined Delphi and Consensus Meeting Process Gunz A, McNally J, Whyte H, O'Hearn K, Foster J, Parker M, Dhanani S 2016 J Pediatr Intensive Care Researchers Clinical research
Differential Expression Analysis by RNA-Seq Reveals Perturbations in the Platelet mRNA Transcriptome Triggered by Pathogen Reduction Systems Osman A, Hitzler WE, Ameur A, Provost P 2015 PLoS One Researchers Basic research
Effect of platelet additive solution on bacterial dynamics and their influence on platelet quality in stored platelet concentrates Greco CA, Zhang JG, Kalab M, Yi Q-L, Ramirez-Arcos SM, Gyongyossy-Issa MIC 2010 Transfusion Researchers Basic research
E-selectin mediated adhesion and migration of endothelial colony forming cells is enhanced by SDF-1alpha/CXCR4 Sun J, Li Y, Graziani GM, Filion L, Allan DS 2013 PLoS One Researchers Basic research
Extracellular vesicles in transfusion-related immunomodulation and the role of blood component manufacturing Almizraq RJ, Seghatchian J, Acker JP 2016 Transfusion and Apheresis Science Researchers Basic research
Human bone marrow mesenchymal stromal cell-derived osteoblasts promote the expansion of hematopoietic progenitors through Beta-catenin and Notch signaling pathways Michalicka M, Boisjoli G, Jahan S, Hovey O, Doxtator E, Abu-Khader A, Pasha R, Pineault N 2017 Stem Cells Dev Researchers Basic research
Mice with deleted multimerin 1 and ?-synuclein genes have impaired platelet adhesion and impaired thrombus formation that is corrected by multimerin 1 Reheman A, Tasneem S, Ni H, Hayward CPM 2010 Thromb Res Researchers Basic research
Mouse background and IVIG dosage are critical in establishing the role of inhibitory Fcgamma receptor for the amelioration of experimental ITP Leontyev D, Katsman Y, Branch DR 2012 Blood Researchers Basic research
Physical characterization of hematopoietic stem cells using multidirectional label-free light scatterings Shahin H, Gupta M, Janowska-Wieczorek A, Rozmus W, Tsui YY 2016 Optics Express Researchers Basic research
Red blood cell replacement, or nanobiotherapeutics with enhanced red blood cell functions? Chang TMS 2015 Artif Cells Nanomed Biotechnol Researchers Basic research