Our Research Publications
Updated November 2023
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Title | Authors | Year | Journal Sort descending | Link to Article | Intended Audience | Purpose |
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What's in a name? Patient registration errors and their threat to transfusion safety | Ning S, Yan MTS, Downie H, Callum J | 2018 | Transfusion | View What's in a name? Patient registration errors and their threat to transfusion safety | Researchers | New or improved product or process |
IgG3 anti-Kell allotypic variation results in differential antigen binding and phagocytosis | Cen SY, Holton MB, Binnington B, Denomme GA, Howie HL, Lebedev JN, Zimring JC, Branch DR | 2020 | Transfusion | View IgG3 anti-Kell allotypic variation results in differential antigen binding and phagocytosis | Researchers | Basic research |
SARS-CoV-2 seroprevalence among blood donors after the first COVID-19 wave in Canada | Saeed S, Drews SJ, Pambrun C, Yi Q-L, Osmond L, O'Brien SF | 2021 | Transfusion | View SARS-CoV-2 seroprevalence among blood donors after the first COVID-19 wave in Canada | Researchers | Clinical research |
Climate change and parasitic risk to the blood supply | Drews SJ, Wendel S, Leiby DA, Tonnetti L, Ushiro-Lumb I, O'Brien SF, Lieshout-Krikke RW, Bloch EM, the International Society of Blood Transfusion Working Party Parasite Subgroup | 2023 | Transfusion | View Climate change and parasitic risk to the blood supply | Blood operators | Clinical research |
National Blood Foundation 2021 Research and Development summit: Discovery, innovation, and challenges in advancing blood and biotherapies | Holmberg JA, Henry SM, Burnouf T, Devine D, Marschner S, Boothby TC, Burger SR, Chou ST, Custer B, Blumberg N, Siegel DL, Spitalnik SL | 2022 | Transfusion | View National Blood Foundation 2021 Research and Development summit: Discovery, innovation, and challenges in advancing blood and biotherapies | Researchers | Benchmarking and standard setting |
Extended storage and glucose exhaustion are associated with apoptotic changes in platelets stored in additive solution | Johnson L, Schubert P, Tan S, Devine DV, Marks DC | 2015 | Transfusion | View Extended storage and glucose exhaustion are associated with apoptotic changes in platelets stored in additive solution | Researchers | Basic research |
How do I interpret a p value? | O'Brien SF, Osmond L, Yi Q-L | 2015 | Transfusion | View How do I interpret a p value? | Researchers | Other |
Impact of ethnicity on human umbilical cord blood banking: a systematic review | Akyurekli C, Chan JY, Elmoazzen H, Tay J, Allan DS | 2014 | Transfusion | View Impact of ethnicity on human umbilical cord blood banking: a systematic review | Researchers | Clinical research |
Proceedings of the Food and Drug Administration's public workshop on new red blood cell product regulatory science 2016 | Vostal JG, Buehler PW, Gelderman MP, Alayash AI, Doctor A, Zimring JC, Glynn SA, Hess JR, Klein H, Acker JP, Spinella PC, D'Alessandro A, Palsson B, Raife TJ, Busch MP, McMahon TJ, Intaglietta M, Swartz HM, Dubick MA, Cardin S, Patel RP, Natanson C, Weisel JW, Muszynski JA, Norris PJ, Ness PM | 2018 | Transfusion | View Proceedings of the Food and Drug Administration's public workshop on new red blood cell product regulatory science 2016 | Researchers | New or improved product or process |
Transfusion-related acute lung injury after transfusion of pooled immune globulin: a case report | Quest GR, Gaal H, Clarke G, Nahirniak S | 2014 | Transfusion | View Transfusion-related acute lung injury after transfusion of pooled immune globulin: a case report | Health care providers | Clinical research |
Assessing opportunities and challenges for establishing a national program to distribute cord blood for research | Isasi R, Mastronardi C, Golder M, Allan D, Walker M, Halpenny M, Yang L, Elmoazzen H, Chargé S | 2018 | Transfusion | View Assessing opportunities and challenges for establishing a national program to distribute cord blood for research | Researchers | Other |
Platelet vesicles are potent inflammatory mediators in red blood cell products and washing reduces the inflammatory phenotype | Almizraq R, Kipkeu B, Acker JP | 2020 | Transfusion | View Platelet vesicles are potent inflammatory mediators in red blood cell products and washing reduces the inflammatory phenotype | Researchers | Basic research |
Exploring the components of bleeding outcomes in transfusion trials for patients with hematologic malignancy | Balitsky AK, Liu Y, Van der Meer PF, Heddle NM, Arnold DM | 2021 | Transfusion | View Exploring the components of bleeding outcomes in transfusion trials for patients with hematologic malignancy | Researchers | Clinical research |
A prospective multi-faceted interventional study of blood bank technologist screening of red blood cell transfusion orders: The START study | Kron AT, Collins A, Cserti-Gazdewich C, Pendergrast J, Webert K, Lieberman L, Zeller MP, Harding SR, Nahirniak S, Prokopchuk-Gauk O, Lin Y, Mendez B, Armali C, Lee C, Watson D, Arnott D, Xun F, Blain H, Panchuk H, Hughes H, Chorneyko K, Angers M, Pilutti N, Lett R, Dowsley S, Ruijs T, Cupido T, Kichinko T, Thompson T, Afshar-Ghotli Z, Callum J, University of Toronto Quality in Utilization, Education and Safety in Transfusion (QUEST) Research Program | 2021 | Transfusion | View A prospective multi-faceted interventional study of blood bank technologist screening of red blood cell transfusion orders: The START study | Health care providers | Clinical research |
From MPOX to the next epidemic: Words matter when talking about equity-deserving groups | Butler-Foster T, Khandelwal A, Montemayor C, Miller YM, Yan MTS, Holmberg JA, Ipe TS, Accooe P, Cancelas JA | 2023 | Transfusion | View From MPOX to the next epidemic: Words matter when talking about equity-deserving groups | Health care providers | Ethical, legal & social implications research |
Serologic reactivity of unidentified specificity in antenatal testing and hemolytic disease of the fetus and newborn: The BEST collaborative study | Lu W, Ziman A, Yan MTS, Waters A, Virk MS, Tran A, Tang H, Shih AW, Scally E, Raval JS, Pandey S, Pagano MB, Shan H, Moore C, Morrison D, Cormack O, Fitzgerald J, Duncan J, Corean J, Clarke G, Yazer M | 2023 | Transfusion | View Serologic reactivity of unidentified specificity in antenatal testing and hemolytic disease of the fetus and newborn: The BEST collaborative study | Health care providers | Clinical research |
Antibody specific for the glycophorin A complex mediates intravenous immune globulin-resistant anemia in a murine model | Chen X, Ghaffar H, Jen CC, Lazarus AH | 2014 | Transfusion | View Antibody specific for the glycophorin A complex mediates intravenous immune globulin-resistant anemia in a murine model | Researchers | Basic research |
Bacterial contamination in platelets: incremental improvements drive down but do not eliminate risk | Jenkins C, Ramirez-Arcos S, Goldman M, Devine DV | 2011 | Transfusion | View Bacterial contamination in platelets: incremental improvements drive down but do not eliminate risk | Blood operators | New or improved product or process |
Blood Group Antigen Matching Influence on Gestational Outcomes (AMIGO) study | Delaney M, Wikman A, van de Watering L, Schonewille H, Verdoes JP, Emery SP, Murphy MF, Staves J, Flach S, Arnold DM, Kaufman RM, Ziman A, Harm SK, Fung M, Eppes CS, Dunbar NM, Buser A, Meyer E, Savoia H, Abeysinghe P, Heddle N, Tinmouth A, Traore AN, Yazer MH, for the Best Collaborative | 2017 | Transfusion | View Blood Group Antigen Matching Influence on Gestational Outcomes (AMIGO) study | Researchers | Clinical research |
Dengue virus persists and replicates during storage of platelet and red blood cell units | Sutherland MR, Simon AY, Serrano K, Schubert P, Acker JP, Pryzdial ELG | 2016 | Transfusion | View Dengue virus persists and replicates during storage of platelet and red blood cell units | Researchers | Basic research |
Fatal false-negative transfusion infection involving a buffy coat platelet pool contaminated with biofilm-positive Staphylococcus epidermidis: a case report | Kou Y, Pagotto F, Hannach B, Ramirez-Arcos S | 2015 | Transfusion | View Fatal false-negative transfusion infection involving a buffy coat platelet pool contaminated with biofilm-positive Staphylococcus epidermidis: a case report | Health care providers | Clinical research |
Improved mouse models for the study of treatment modalities for immune-mediated platelet destruction | Katsman Y, Foo AH, Leontyev D, Branch DR | 2010 | Transfusion | View Improved mouse models for the study of treatment modalities for immune-mediated platelet destruction | Researchers | Basic research |
Safety of blood donation by individuals over age 70 and their contribution to the blood supply in five developed countries: a BEST Collaborative group study | Goldman M, Germain M, Gregoire Y, Vassallo RR, Kamel H, Bravo M, Irving DO, Di Angelantonio E, Steele WR, O'Brien SF, for the Biomedical Excellence for Safer Transfusion Collaborative (BEST) Investigators | 2019 | Transfusion | View Safety of blood donation by individuals over age 70 and their contribution to the blood supply in five developed countries: a BEST Collaborative group study | Blood operators | New or improved product or process |
Translating red cell "omics" into new perspectives in transfusion medicine: mining the gems in the data mountains | Spitalnik SL, Devine DV | 2019 | Transfusion | View Translating red cell "omics" into new perspectives in transfusion medicine: mining the gems in the data mountains | Researchers | Other |
Differential red blood cell age fractionation and Band?3 phosphorylation distinguish two different subtypes of warm autoimmune hemolytic anemia | Bloch EM, Branch HA, Sakac D, Leger RM, Branch DR | 2020 | Transfusion | View Differential red blood cell age fractionation and Band?3 phosphorylation distinguish two different subtypes of warm autoimmune hemolytic anemia | Researchers | Basic research |
2-HG inhibits necroptosis by stimulating DNMT1-dependent hypermethylation of the RIP3 promoter | Yang Z, Jiang B, Wang Y, Ni H, Zhang J, Xia J, Shi M, Hung L, Ruan J, Mak T, Li Q, Han J | 2017 | Cell Rep | View 2-HG inhibits necroptosis by stimulating DNMT1-dependent hypermethylation of the RIP3 promoter | Researchers | Basic research |
A 13-question approach to resolving serological discrepancies in the transfusion medicine laboratory | Yudin J, Heddle NM | 2014 | Lab Med | View A 13-question approach to resolving serological discrepancies in the transfusion medicine laboratory | Health care providers | Clinical research |
Cardiorespiratory pathogenesis of sickle cell disease in a mouse model | Ren J, Ding X, Trudel M, Greer JJ, MacLean JE | 2017 | Sci Rep | View Cardiorespiratory pathogenesis of sickle cell disease in a mouse model | Researchers | Basic research |
Correction of haemorrhagic shock-associated coagulopathy and impaired haemostasis by plasma, prothrombin complex concentrates or an activated protein C-targeted DNA aptamer in mice | Eltringham-Smith LJ, Meixner SC, Pryzdial ELG, Sheffield WP | 2023 | Sci Rep | View Correction of haemorrhagic shock-associated coagulopathy and impaired haemostasis by plasma, prothrombin complex concentrates or an activated protein C-targeted DNA aptamer in mice | Researchers | Basic research |
IVIG regulates the survival of human but not mouse neutrophils | Schneider C, Wicki S, Graeter S, Timcheva TM, Keller CW, Quast I, Leontyev D, Djoumerska-Alexieva IK, Kasermann F, Jakob SM, Peyta D, Branch D, Cummings J, Kaufmann T, Simon H, Von Gunten S | 2017 | Sci Rep | View IVIG regulates the survival of human but not mouse neutrophils | Researchers | Basic research |
Selection and characterization of a DNA aptamer inhibiting coagulation factor XIa | Donkor DA, Bhakta V, Eltringham-Smith LJ, Stafford AR, Weitz JI, Sheffield WP | 2017 | Sci Rep | View Selection and characterization of a DNA aptamer inhibiting coagulation factor XIa | Researchers | Basic research |
QSAR accelerated discovery of potent ice recrystallization inhibitors | Briard JG, Fernandez M, De Luna P, Woo TK, Ben RN | 2016 | Sci Rep | View QSAR accelerated discovery of potent ice recrystallization inhibitors | Researchers | Basic research |
Co-administration of FVIII with IVIG reduces immune response to FVIII in hemophilia A mice | Afraz S, Stevic I, Matino D, Wen J, Atkinson H, Chan AKC, Hortelano G | 2022 | Sci Rep | View Co-administration of FVIII with IVIG reduces immune response to FVIII in hemophilia A mice | Researchers | Clinical research |
Deformability based cell sorting using microfluidic ratchets enabling phenotypic separation of leukocytes directly from whole blood | Guo Q, Duffy SP, Matthews K, Islamzada E, Ma H | 2017 | Sci Rep | View Deformability based cell sorting using microfluidic ratchets enabling phenotypic separation of leukocytes directly from whole blood | Researchers | New or improved product or process |
Small Molecule Ice Recrystallization Inhibitors Enable Freezing of Human Red Blood Cells with Reduced Glycerol Concentrations | Capicciotti CJ, Kurach JDR, Turner TR, Mancini RS, Acker JP, Ben RN | 2015 | Sci Rep | View Small Molecule Ice Recrystallization Inhibitors Enable Freezing of Human Red Blood Cells with Reduced Glycerol Concentrations | Researchers | New or improved product or process |
Small molecule ice recrystallization inhibitors mitigate red blood cell lysis during freezing, transient warming and thawing | Briard JG, Poisson JS, Turner TR, Capicciotti CJ, Acker JP, Ben RN | 2016 | Sci Rep | View Small molecule ice recrystallization inhibitors mitigate red blood cell lysis during freezing, transient warming and thawing | Researchers | New or improved product or process |
CD8(+) T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia | Qiu J, Liu X, Li X, Zhang X, Han P, Zhou H, Shao L, Hou Y, Min Y, Kong Z, Wang Y, Wei Y, Liu X, Ni H, Peng J, Hou M | 2016 | Sci Rep | View CD8(+) T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia | Researchers | Basic research |
In vitro assessment and phase I randomized clinical trial of anfibatide a snake venom derived anti-thrombotic agent targeting human platelet GPIb? | Li BX, Dai X, Xu XR, Adili R, Neves MAD, Lei X, Shen C, Zhu G, Wang Y, Zhou H, Hou Y, Ni T, Pasman Y, Yang Z, Qian F, Zhao Y, Gao Y, Liu J, Teng M, Marshall AH, Cerenzia EG, Li ML, Ni H | 2021 | Sci Rep | View In vitro assessment and phase I randomized clinical trial of anfibatide a snake venom derived anti-thrombotic agent targeting human platelet GPIb? | Researchers | Clinical research |
Identification of an alpha-1 antitrypsin variant with enhanced specificity for factor XIa by phage display, bacterial expression, and combinatorial mutagenesis | Bhakta V, Hamada M, Nouanesengsy A, Lapierre J, Perruzza DL, Sheffield WP | 2021 | Sci Rep | View Identification of an alpha-1 antitrypsin variant with enhanced specificity for factor XIa by phage display, bacterial expression, and combinatorial mutagenesis | Researchers | Basic research |
A biochemical network can control formation of a synthetic material by sensing numerous specific stimuli | Hun Yeon J, Chan KYT, Wong T-C, Chan K, Sutherland MR, Ismagilov RF, Pryzdial ELG, Kastrup CJ | 2015 | Sci Rep | View A biochemical network can control formation of a synthetic material by sensing numerous specific stimuli | Researchers | Basic research |
Revealing the diversity of extracellular vesicles using high-dimensional flow cytometry analyses | Marcoux G, Duchez A-C, Cloutier N, Provost P, Nigrovic PA, Boilard E | 2016 | Sci Rep | View Revealing the diversity of extracellular vesicles using high-dimensional flow cytometry analyses | Researchers | Basic research |
Prothrombin, alone or in complex concentrates or plasma, reduces bleeding in a mouse model of blood exchange-induced coagulopathy | Eltringham-Smith LJ, Yu R, Qadri SM, Wang Y, Bhakta V, Pryzdial EL, Crosby JR, Ni H, Sheffield WP | 2019 | Sci Rep | View Prothrombin, alone or in complex concentrates or plasma, reduces bleeding in a mouse model of blood exchange-induced coagulopathy | Researchers | Basic research |
Accelerated apoptotic death and in vivo turnover of erythrocytes in mice lacking functional mitogen- and stress-activated kinase MSK1/2 | Lang E, Bissinger R, Fajol A, Salker MS, Singh Y, Zelenak C, Ghashghaeinia M, Gu S, Jilani K, Lupescu A, Reyskens KM, Ackermann TF, Foller M, Schleicher E, Sheffield WP, Arthur JS, Lang F, Qadri SM | 2015 | Sci Rep | View Accelerated apoptotic death and in vivo turnover of erythrocytes in mice lacking functional mitogen- and stress-activated kinase MSK1/2 | Researchers | Basic research |
Carbohydrate-based ice recrystallization inhibitors increase infectivity and thermostability of viral vectors | Ghobadloo SM, Balcerzak AK, Gargaun A, Muharemagic D, Mironov GG, Capicciotti CJ, Briard JG, Ben RN, Berezovski MV | 2014 | Sci Rep | View Carbohydrate-based ice recrystallization inhibitors increase infectivity and thermostability of viral vectors | Researchers | Basic research |
A bioinformatics approach to identify natural autoantibodies from healthy blood donors' sera reactive with the HCV NS5A-derived peptide by immunoassay | Vasiljevic N, Veljkovic N, Kosec T, Ma XZ, Glisic S, Prljic J, Vujicic AD, Markovic L, Branch DR | 2011 | Viral Immunol | View A bioinformatics approach to identify natural autoantibodies from healthy blood donors' sera reactive with the HCV NS5A-derived peptide by immunoassay | Researchers | Basic research |
Bacterial neuraminidase-mediated erythrocyte desialylation provokes cell surface aminophospholipid exposure | Qadri SM, Donkor DA, Nazy I, Branch DR, Sheffield WP | 2018 | Eur J Haematol | View Bacterial neuraminidase-mediated erythrocyte desialylation provokes cell surface aminophospholipid exposure | Researchers | Basic research |
Impact of osteoblast maturation on their paracrine growth enhancing activity on cord blood progenitors | Alsheikh M, Abu?Khader A, Michalicka M, Pasha R, Pineault N | 2017 | Eur J Haematol | View Impact of osteoblast maturation on their paracrine growth enhancing activity on cord blood progenitors | Researchers | Basic research |
How we treat paroxysmal nocturnal hemoglobinuria: A consensus statement of the Canadian PNH Network and review of the national registry | Patriquin CJ, Kiss T, Caplan S, Chin-Yee I, Grewal K, Grossman J, Larratt L, Marceau D, Nevill T, Sutherland DR, Wells RA, Leber B | 2019 | Eur J Haematol | View How we treat paroxysmal nocturnal hemoglobinuria: A consensus statement of the Canadian PNH Network and review of the national registry | Researchers | Clinical research |
Gender and BCR-ABL transcript type are correlated with molecular response to imatinib treatment in patients with chronic myeloid leukemia | Lin HX, Sjaarda J, Dyck J, Stringer R, Hillis C, Harvey M, Carter R, Ainsworth P, Leber B, Pare G, Sadikovic B | 2016 | Eur J Haematol | View Gender and BCR-ABL transcript type are correlated with molecular response to imatinib treatment in patients with chronic myeloid leukemia | Researchers | Clinical research |
Utilization of a surgical database to provide care and assess perioperative treatment and outcomes in patients with bleeding disorders | Olasupo OO, Haddix C, Nakar C, Maahs J, Greist A, Ghafoor A, Donfield SM, Iorio A, Shapiro AD | 2022 | Eur J Haematol | View Utilization of a surgical database to provide care and assess perioperative treatment and outcomes in patients with bleeding disorders | Health care providers | Benchmarking and standard setting |