Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Comparative characterisation of the biofilm-production abilities of Staphylococcus epidermidis isolated from human skin and platelet concentrates Taha M, Kohnen C, Mallya S, Kou Y, Zapata A, Ramirez-Arcos S 2018 J Med Microbiol View Researchers New or improved product or process
Cytokine profiles in mouse models of experimental immune thrombocytopenia reveal a lack of inflammation and differences in response to intravenous immunoglobulin depending on the mouse strain Leontyev D, Neschadim A, Branch DR 2014 Transfusion View Researchers Basic research
Dicer1 mediated miRNA processing shapes the mRNA profile and function of murine platelets Rowley JW, Chappaz S, Corduan A, Chong MM, Campbell R, Khoury A, Manne BK, Wurtzel JG, Michael JV, Goldfinger LE, Mumaw MM, Nieman MT, Kile BT, Provost P, Weyrich AS 2016 Blood View Researchers Basic research
Effect of blood donor characteristics on transfusion outcomes: a protocol for systematic review and meta-analysis Chasse M, English S, McIntyre L, Knoll G, Shehata N, Forster A, Wilson K, van Walraven C, Tinmouth A, Fergusson D 2014 Syst Rev View Researchers Clinical research
Extracellular histones identified in crocodile blood inhibit in-vitro HIV-1 infection Kozlowski HN, Lai ET, Havugimana PC, White C, Emili A, Sakac D, Binnington B, Neschadim A, McCarthy SD, Branch DR 2016 AIDS View Researchers Basic research
Fusion of the C-terminal triskaidecapeptide of hirudin variant 3 to alpha1-proteinase inhibitor M358R increases the serpin-mediated rate of thrombin inhibition Roddick LA, Bhakta V, Sheffield W 2013 BMC Biochem View Researchers Basic research
Mesenchymal stromal cells derived from umbilical cord blood migrate in response to complement C1q Qiu Y, Marquez-Curtis LA, Janowska-Wieczorek A 2012 Cytotherapy View Researchers Basic research
Moonlighting glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is required for efficient hepatitis C virus and dengue virus infections in human Huh-7.5.1 cells Raj M, Langley M, McArthur SJ, Jean F 2017 J Gen Virol View Researchers Basic research
Optimal Attenuation of Experimental Autoimmune Encephalomyelitis by Intravenous Immunoglobulin Requires an Intact Interleukin-11 Receptor Figueiredo CA, Drohomyrecky PC, McCarthy SDS, Leontyev D, Ma X-Z, Branch DR, Dunn SE 2014 PLoS One View Researchers Basic research
Phosphatidylserine externalization and procoagulant activation of erythrocytes induced by Pseudomonas aeruginosa virulence factor pyocyanin Qadri SM, Donkor DA, Bhakta V, Eltringham-Smith LJ, Dwivedi DJ, Moore JC, Pepler L, Ivetic N, Nazi I, Fox-Robichaud AE, Liaw PC, Sheffield WP 2016 J Cell Mol Med View Researchers Basic research
Platelets and platelet alloantigens: lessons from human patients and animal models of fetal and neonatal alloimmune thrombocytopenia Vadasz B, Chen P, Yougbare I, Zdravic D, Li J, Li C, Carrim N, Ni H 2015 Genes Dis View Researchers Other
Producing megakaryocytes from a human peripheral blood source Ivetic N, Nazi I, Karim N, Clare R, Smith JW, Moore JC, Hope KJ, Kelton JG, Arnold DM 2016 Transfusion View Researchers Basic research
Red blood cell membrane grafting of multi-functional hyperbranched polyglycerols Rossi NAA, Constantinescu I, Kainthan RK, Brooks DE, Scott MD, Kizhakkedathu JN 2010 Biomaterials View Researchers Basic research
Structure-activity relationships of pyrazole derivatives as potential therapeutics for immune thrombocytopenias Purohit MK, Chakka SK, Scovell I, Neschadim A, Bello AM, Salum N, Katsman Y, Bareau MC, Branch DR, Kotra LP 2014 Bioorg Med Chem View Researchers Basic research
The clinical significance of platelet microparticle-associated microRNAs Provost P 2017 Clin Chem Lab Med View Researchers Basic research
The maternal immune response to fetal platelet GPIb? causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies Li C, Piran S, Chen P, Lang S, Zarpellon A, Jin JW, Zhu G, Reheman A, van der Wal DE, Simpson EK, Ni R, Gross PL, Ware J, Ruggeri ZM, Freedman J, Ni H 2011 J Clin Invest View Researchers Basic research
Thrombin a-chain: activation remnant or allosteric effector? Carter IS, Vanden Hoek AL, Pryzdial EL, Macgillivray RT 2010 Thrombosis View Researchers Basic research
Virtual screen for repurposing approved and experimental drugs for candidate inhibitors of EBOLA virus infection Veljkovic V, Loiseau PM, Figadere B, Glisic S, Veljkovic N, Perovic VR, Cavanaugh DP, Branch DR 2015 F1000Res View Researchers Basic research
Concentré de recherche : Un sur un million : un modèle pour gérer les réserves de sang rare Blake J, Clarke G 2019 Blood.ca website View Researchers Clinical research
Cardiac stress biomarkers after red blood cell transfusion in patients at risk for transfusion-associated circulatory overload: a prospective observational study Callum JL, Cohen R, Cressman AM, Strauss R, Armali C, Lin Y, Pendergrast J, Lieberman L, Scales DC, Skeate R, Ross H, Cserti-Gazdewich C 2018 Transfusion View Researchers Clinical research
Electronic patient identification for sample labeling reduces wrong blood in tube errors Kaufman RM, Dinh A, Cohn CS, Fung MK, Gorlin J, Melanson S, Murphy MF, Ziman A, Elahie AL, Chasse D, Degree L, Dunbar NM, Dzik WH, Flanagan P, Gabert K, Ipe TS, Jackson B, Lane D, Raspollini E, Ray C, Sharon Y, Ellis M, Selleng K, Staves J, Yu P, Zeller M, Yazer M, BEST Collaborative 2018 Transfusion View Researchers Clinical research
Trends in IVIG use at a tertiary care Canadian center and impact of provincial use mitigation strategies: 10-year retrospective study with interrupted time series analysis Murphy MSQ, Tinmouth A, Goldman M, Chasse M, Colas JA, Saidenberg E, Shehata N, Fergusson D, Forster AJ, Wilson K 2019 Transfusion View Researchers Clinical research
Syndrome respiratoire aigu post-transfusionnel (TRALI) Petraszko T 2019 Blood.ca website View Researchers Clinical research
Glycoprotein V is a relevant immune target in patients with immune thrombocytopenia Vollenberg R, Jouni R, Norris PAA, Burg-Roderfeld M, Cooper N, Rummel MJ, Bein G, Marini I, Bayat B, Burack R, Lazarus AH, Bakchoul T, Sachs UJ 2019 Haematologica View Researchers Basic research
ResearchUnit: Fighting inflammation with inflammation Lazarus A 2019 Blood.ca website View Researchers Clinical research
Treating murine inflammatory diseases with an anti-erythrocyte antibody Crow AR, Kapur R, Koernig S, Campbell IK, Jen C-C, Mott PJ, Marjoram D, Khan R, Kim M, Brasseit J, Cruz-Leal Y, Amash A, Kahlon S, Yougbare I, Ni H, Zuercher AW, Käsermann F, Semple JW, Lazarus AH 2019 Sci Transl Med View Researchers Basic research
A comparative study of platelet factor 4-enhanced platelet activation assays for the diagnosis of heparin-induced thrombocytopenia Rubino JG, Arnold DM, Warkentin TE, Smith JW, Kelton JG, Nazy I 2021 J Thromb Haemost View Researchers Basic research
Half a Century of Wilson & Jungner: Reflections on the Governance of Population Screening Sturdy S, Miller F, Hogarth S, Armstrong N, Chakraborty P, Cressman C, Dobrow M, Flitcroft K, Grossman D, Harris R, Hoebee B, Holloway K, Kinsinger L, Krag M, Löblová O, Löwy I, Mackie A, Marshall J, O'Hallahan J, Rabeneck L, Raffle A, Reid L, Shortland G, Steele R, Tarini B, Taylor-Phillips S, Towler B, van der Veen N, Zappa M 2020 Wellcome Open Res View Researchers Other
Public Goods, or Goods for the Public? The Commercialization of Academic Health Research Holloway K, Herder M 2020 Health Matters: Evidence, Critical Social Science, and Health Care in Canada View Researchers Ethical, legal and social implications research
Targeted recruitment of optimal donors for unrelated hematopoietic cell transplantation: The Stem Cell Club process Fingrut W, Messner HA, Allan D 2020 Hematol Oncol Stem Cell Ther View Researchers New or improved product or process
Differential Leukocyte MicroRNA Responses Following Pan T Cell, Allorecognition and Allosecretome-Based Therapeutic Activation Yang X, Toyofuku WM, Scott MD 2021 Arch Immunol Ther Exp View Researchers Basic research
Soy Isoflavones Inhibit Both GPIb-IX Signaling and ?IIb?3 Outside-In Signaling via 14-3-3? in Platelet Liu M, Wang G, Xu R, Shen C, Ni H, Lai R 2021 Molecules View Researchers Basic research
Degradation of red blood cell deformability during cold storage in blood bags Islamzada E, Matthews K, Lamoureux ES, Duffy SP, Scott MD, Ma H 2021 eJHaem View Researchers Basic research
Cultured CD71+ erythroid cells modulate the host immune response Alshalani A, Beuger BM, van Bruggen R, Acker JP, Juffermans NP 2023 Transfus Med View Researchers Basic research
Behaviour based screening questions and potential donation loss using the “for the assessment of individualised risk” screening criteria: A Canadian perspective Caffrey N, Goldman M, Lewin A, Osmond L, O'Brien SF 2022 Transfus Med View Researchers MSM research
Antibody-Mediated Immune Suppression of Erythrocyte Alloimmunization Can Occur Independently from Red Cell Clearance or Epitope Masking in a Murine Model Yu H, Stowell SR, Bernardo L, Hendrickson JE, Zimring JC, Amash A, Uchikawa M, Lazarus AH 2014 J Immunol View Researchers Basic research
Bacterial neuraminidase-mediated erythrocyte desialylation provokes cell surface aminophospholipid exposure Qadri SM, Donkor DA, Nazy I, Branch DR, Sheffield WP 2018 Eur J Haematol View Researchers Basic research
Characterization of the growth modulatory activities of osteoblast conditioned media on cord blood progenitor cells Abu-Khader A, Pasha R, Ward GCD, Boisjoli G, Pineault N 2016 Cytotechnology View Researchers Basic research
Concentré de recherche: Cellules tueuses naturelles : quand les cellule perdent le nord! Ni H 2017 Blood.ca website View Researchers Basic research
Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia Li J, van der Wal DE, Zhu G, Xu M, Yougbare I, Ma L, Vadasz B, Carrim N, Grozovsky R, Ruan M, Zhu L, Zeng Q, Tao L, Zhai Z-m, Peng J, Hou M, Leytin V, Freedman J, Hoffmeister KM, Ni H 2015 Nat Commun View Researchers Basic research
Efficacy and safety of mesenchymal stromal cells in preclinical models of acute lung injury: a systematic review protocol Lalu MM, Moher D, Marshall J, Fergusson D, Mei SH, Macleod M, Griffin G, Turgeon AF, Rudnicki M, Fishman J, Avey MT, Skidmore B, Grimshaw JM, Stewart DJ, Singh K, McIntyre L 2014 Syst Rev View Researchers Clinical research
Evaluating the role of IL-11, a novel cytokine in the IL-6 family, in a mouse model of spinal cord injury Cho N, Nguyen DH, Satkunendrarajah K, Branch DR, Fehlings MG 2012 J Neuroinflammation View Researchers Basic research
Fc-independent immune thrombocytopenia via mechanomolecular signaling in platelets Quach ME, Dragovich MA, Chen W, Syed AK, Cao W, Liang X, Deng W, De Meyer SF, Zhu G, Peng J, Ni H, Bennett CM, Hou M, Ware J, Deckmyn H, Zhang XF, Li R 2018 Blood View Researchers Basic research
Improved resolution in extracellular vesicle populations using 405 instead of 488 nm side scatter McVey MJ, Spring CM, Kuebler WM 2018 J Extracell Vesicles View Researchers Basic research
Introduction to the Special Issue: Teaching Healthcare Operations Research, Part 1 Blake J 2016 INFORMS Transactions on Education View Researchers Other
Microparticle and mitochondrial release during extended storage of different types of platelet concentrates Marcoux G, Duchez A-C, Rousseau M, Levesque T, Boudreau LH, Thibault L, Boilard E 2016 Platelets View Researchers Basic research
Nanoformulated water-soluble paclitaxel to enhance drug efficacy and reduce hemolysis side effect Gu W, Chen J, Patra P, Yang X, Gu Q, Wei L, Acker J, Kong B 2017 J Biomater Appl View Researchers Basic research
p38 mitogen-activated protein kinase regulates mitochondrial function and microvesicle release in riboflavin- and ultraviolet light–treated apheresis platelet concentrates Chen Z, Schubert P, Bakkour S, Culibrk B, Busch MP, Devine DV 2017 Transfusion View Researchers Basic research
Plasma fibronectin supports hemostasis and regulates thrombosis Wang Y, Reheman A, Spring CM, Kalantari J, Marshall AH, Wolberg AS, Gross PL, Weitz JI, Rand ML, Mosher DF, Freedman J, Ni H 2014 J Clin Invest View Researchers Basic research
Positioning new treatments in the management of immune thrombocytopenia Arnold DM 2013 Pediatr Blood Cancer View Researchers Clinical research