Our Funded Research Projects

Updated April 2024

Title Principal Investigator / Supervisor Program Sort ascending Project Start Date Project End Date Total $ Awarded
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: LAU, Wendy

Co-Investigator(s) / Trainee: TORDON, Bryan
Elianna Saidenberg Transfusion Medicine Traineeship Award 210000.0
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: LAU, Wendy

Co-Investigator(s) / Trainee: VANDERMEULEN, Heather
Elianna Saidenberg Transfusion Medicine Traineeship Award 210000.0
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: SHIH, Andrew

Co-Investigator(s) / Trainee: TAPLEY, Laura
Elianna Saidenberg Transfusion Medicine Traineeship Award 105000.0
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: ZELLER, Michelle

Co-Investigator(s) / Trainee: GABARIN, Nadia
Elianna Saidenberg Transfusion Medicine Traineeship Award 210000.0
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: LIN, Yulia

Co-Investigator(s) / Trainee: ARYA, Sumedha
Elianna Saidenberg Transfusion Medicine Traineeship Award 210000.0
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: LIN, Yulia

Co-Investigator(s) / Trainee: ROTIN, Lianne
Elianna Saidenberg Transfusion Medicine Traineeship Award 210000.0
Elianna Saidenberg Transfusion Medicine Trainee Principal Investigator: LIN, Yulia

Co-Investigator(s) / Trainee: RAZA, Sheharyar
Elianna Saidenberg Transfusion Medicine Traineeship Award 210000.0
Process evaluation of the Canadian Blood Services' cord blood bank: managerial and donor perspectives Principal Investigator: DEVINE, Dana

Co-Investigator(s) / Trainee: HAW, Jennie
CIHR Health System Impact Fellowship 46500.0
Options for increasing plasma supply in Canada: A health economic preference and modelling study Principal Investigator: HOLLOWAY, Kelly

Co-Investigator(s) / Trainee: KENNEDY, Kevin
CIHR Health System Impact Fellowship 108500.0
Leveraging equity-focused implementation science to evaluate and support the re-integration of men who have sex with men into the blood donation system Principal Investigator: GOLDMAN, Mindy

Co-Investigator(s) / Trainee: VESNAVER, Elisabeth
CIHR Health System Impact Fellowship 108500.0
Myocardial Ischemia and Transfusion. The MINT rollover trial Principal Investigator: HEBERT, Paul

Co-Investigator(s) / Trainee: CARSON, Jeffrey L., DEVEREAUX, Philip J., EIKELBOOM, John W., FERGUSSON, Dean A., GOODMAN, Shaun G. , MCALISTER, Finlay A. , TINMOUTH, Alan T.
Canadian Blood Services-CIHR Partnership Operating Grant Program 140210.0
Platelet microRNAs during storage under blood bank conditions Principal Investigator: PROVOST, Patrick

Co-Investigator(s) / Trainee: HITZLER, Walter
Canadian Blood Services-CIHR Partnership Operating Grant Program 349548.0
Pathogenesis and treatment of immune thrombocytopenia: Are there fundamental differences between anti-GPlba- and anti-GPllbllla-mediated thrombocytopenia? Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership Operating Grant Program 378529.0
Fetal and neonatal alloimmune thrombocytopenia: novel mechanisms and therapeutic approaches Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership Operating Grant Program 471393.0
Transfusion of red cells in hematopoietic stem cell transplantation: The TRIST Study Principal Investigator: TAY, Jason

Co-Investigator(s) / Trainee: ALLAN, David S. , COYLE, Douglas A. , FERGUSSON, Dean A. , TINMOUTH, Alan T. , WALKER, Irwin R
Canadian Blood Services-CIHR Partnership Operating Grant Program 340817.0
Mechanisms of antibody-independent transfusion-related acute lung injury (TRALI) Principal Investigator: KUEBLER, Wolfgang

Co-Investigator(s) / Trainee: SEMPLE, John W.
Canadian Blood Services-CIHR Partnership Operating Grant Program 328712.0
Novel mechanisms of platelet aggregation: Roles of non-classical beta-3 integrin ligands and fibronectin in thrombosis and hemostasis Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership Operating Grant Program 398871.0
Transfusion-related Epstein-Barr Virus (EBV) infection among allogeneic stem cell transplant pediatric recipients: A multicenter prospective cohort study (TREASuRE Study) Principal Investigator: TROTTIER, Helen

Co-Investigator(s) / Trainee: ALFIERI, Carolina , BUTEAU, Chantal , DUVAL, Michel , LACROIX, Jacques , ROBITAILLE, Nancy , SPINELLA, Philip , TUCCI, Marisa
Canadian Blood Services-CIHR Partnership Operating Grant Program 519766.0
Short and long-term clinical effects of blood donor characteristics in transfusion recipients Principal Investigator: FERGUSSON, Dean

Co-Investigator(s) / Trainee: ACKER, Jason P., CHASSÉ, Michael, ENGLISH, Shane, FORSTER, Alan, KNOLL, Greg, McINTYRE, Lauralyn A., SHEHATA, Nadine , van WALRAVEN, Carl, WILSON, Kumanan , TINMOUTH, Alan T.
Canadian Blood Services-CIHR Partnership Operating Grant Program 103806.0
Expanding treatment options for inflammatory bowel disease: A novel mechanism of antibody-based immunotherapy Principal Investigator: SLY, Laura

Co-Investigator(s) / Trainee: HORWITZ, Marc, BRESSLER, Brian, RASSEKH, Rod, TURVEY, Stuart
Canadian Blood Services-CIHR Partnership Operating Grant Program 408540.6
Tranexamic acid versus placebo to reduce perioperative blood transfusion in patients undergoing major liver resection: a pilot randomized controlled trial Principal Investigator: KARANICOLAS, Paul

Co-Investigator(s) / Trainee: GUYATT, Gordon H. , CHAUDHURY, Prosanto K. , DIXON, Elijah , LIN, Yulia , McCLUSKEY, Stuart A. , PORTER, Geoffrey A. , TARSHIS, Jordan , WEI, Alice C.
Canadian Blood Services-CIHR Partnership Operating Grant Program 248319.0
Exploratory analyses to determine if method of donor blood processing affects outcome in transfused recipients Principal Investigator: HEDDLE, Nancy

Co-Investigator(s) / Trainee: ACKER, Jason P. , ARNOLD, Donald M. , COOK, Richard J. , EIKELBOOM, John W. , O'BRIEN, Sheila F. , WEBERT, Kathryn E.
Canadian Blood Services-CIHR Partnership Operating Grant Program 159878.0
Understanding host mechanisms responsible for immune platelet destruction and thrombocytopenia Principal Investigator: SEMPLE, John

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership Operating Grant Program 406003.0
Examining the relationship between repeated blood donations in female donors on maternal/neonatal outcomes: a cohort study Principal Investigator: TINMOUTH, Alan

Co-Investigator(s) / Trainee: CHASSE, Michael, FERGUSSON, Dean A., GOLDMAN, Mindy R., O'BRIEN, Sheila F., SPRAGUE, Ann, van WALRAVEN, Carl, WALKER, Mark C., WILSON, Kumanan
Canadian Blood Services-CIHR Partnership Operating Grant Program 135657.0
Polyhemoglobin catalase superoxide dismutase carbonic anhydrase: a novel soluble biotherapeutic with no cardiac toxicity for hemorrhagic shock and other uses Principal Investigator: CHANG, Thomas

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership Operating Grant Program 224520.0
Identification of host cellular immune mechanisms responsible for the initiation and/or modulation of Transfusion Related Acute Lung Injury (TRALI) Principal Investigator: SEMPLE, John

Co-Investigator(s) / Trainee: KUEBLER, Wolfgang M.
Canadian Blood Services-CIHR Partnership Operating Grant Program 398982.0
Characterization of the hematopoietic reconstitution enhancing activity of osteoblasts derived from human mesenchymal stromal cells Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: CAMPBELL, Pearl , GARNIER, Alain
Canadian Blood Services-CIHR Partnership Operating Grant Program 320504.0
Transfusion-Related Acute Lung Injury and delayed TRALI: a prospective study in critically ill children Principal Investigator: EMERIAUD, Guillaume

Co-Investigator(s) / Trainee: DU PONT-THIBIDEAU, Genevieve, FONTELA, Patricia S. , GAUVIN, France, GILFOYLE, Elaine, HUTCHISON, James S., LACROIX, Jacques, MENON, Kusum, ROBITAILLE, Nancy, TINMOUTH, Alan T., TROTTIER, Helen
Canadian Blood Services-CIHR Partnership Operating Grant Program 477651.0
The use of antibody-mediated immune suppression as a model in the development of a replacement for RhD prophylaxis in haemolytic disease of the fetus and newborn Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership Operating Grant Program 620822.0
Design and implementation of circulatory oxygen therapeutics derived from human hemoglobin by improved systematic chemical coupling and cross-linking Principal Investigator: KLUGER, Ronald

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership Operating Grant Program 192039.0
Defining disease mechanisms in Immune Thrombocytopenia (ITP) and their association with clinical outcomes Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee: COOK, Richard J., NAZY, Ishac
Canadian Blood Services-CIHR Partnership Operating Grant Program 317469.0
Improving the cryostorage of blood products using novel small molecule cryoprotectants Principal Investigator: BEN, Robert

Co-Investigator(s) / Trainee: ACKER, Jason P. , ALLAN, David S.
Canadian Blood Services-CIHR Partnership Operating Grant Program 384180.0
Release, delivery and cell programming effects of platelet microparticles and microRNAs Principal Investigator: PROVOST, Patrick

Co-Investigator(s) / Trainee: BOILARD, Eric
Canadian Blood Services-CIHR Partnership Operating Grant Program 427422.0
Polymer-based manufacturing tolerogenic miRNA-based therapeutics Principal Investigator: SCOTT, Mark

Co-Investigator(s) / Trainee: HORWITZ, Marc S.
Canadian Blood Services-CIHR Partnership Operating Grant Program 491125.0
Small molecule inhibitors of phagocytosis as replacement therapy for IVIG Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: KOTRA, Lakshmi, P.
Canadian Blood Services-CIHR Partnership Operating Grant Program 230000.0
Microfluidic devices to measure the deformability of stored red blood cells Principal Investigator: MA, Hongshen

Co-Investigator(s) / Trainee: SCOTT, Mark D.
Canadian Blood Services-CIHR Partnership Operating Grant Program 398301.0
Aneurysmal SubArachnoid Hemorrhage - Red blood cell transfusion And outcome (SAHaRA): a pilot randomized controlled trial Principal Investigator: ENGLISH, Shane

Co-Investigator(s) / Trainee: McINTYRE, Lauralyn A. , ALGIRD, Almunder , BOUTIN, Amélie , CHASSE, Michael , DOWLATSHAHI, Dariush , FERGUSSON, Dean A. , GRIESDALE, Donald , KRAMER, Andreas H. , LAUZIER, François , LUM, Cheemun , MARSHALL, Shawn C. , PAGLIARELLO, Giuseppe , SINCLAIR, John , TINMOUTH, Alan T. , TURGEON, Alexis F.
Canadian Blood Services-CIHR Partnership Operating Grant Program 157172.0
Development of novel blood vessel and organ sealants for blood conservation in surgical practice Principal Investigator: BROOKS, Don

Co-Investigator(s) / Trainee: DU, Caigan , HSIANG, York N. , KIZHAKKEDATHU, Jayachandran N. , KO, Frank K.
Canadian Blood Services-CIHR Partnership Operating Grant Program 240996.0
Understanding transcriptional and epigenetic control by Gfi1b towards the development of a therapy for sickle cell disease Principal Investigator: TRUDEL, Marie

Co-Investigator(s) / Trainee: MOROY, Tarik
Canadian Blood Services-CIHR Partnership Operating Grant Program 453132.0
Transfusion requirements in cardiac surgery (TRICS II) Principal Investigator: SHEHATA, Nadine

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership New Investigator Program 300000.0
Code sepsis: defining and translating optimal resuscitation and care for children with septic shock Principal Investigator: PARKER, Melissa

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership New Investigator Program 300000.0
Pediatric Transfusion Camp Principal Investigator: LIEBERMAN, Lani

Co-Investigator(s) / Trainee: LIN, Yulia, CALLUM, Jeannie, WALSH, Catherine, CHARGÉ, Sophie, WILLIAMS, Suzanne, FARONI, David, MEMA, Briseida, LACROIX, Jacque, LAU, Wendy, ROBITAILLE, Nancy, FINAN, Emer, HUME, Heather, HASPEL, Richard, ATKINSON, Adelle, SCOLNIK, Dennis
BloodTechNet Award Program 10500.0
Podcast for FNAIT and ICTMG red cell specifications for hemoglobinopathies guidelines Principal Investigator: SHEHATA, Nadine

Co-Investigator(s) / Trainee:
BloodTechNet Award Program 6200.0
Transfusion CONsent by a Standardized Evidence-based Novel Tool (Transfusion- CONSENT): Creating and validating novel tools to assess competence in obtaining transfusion consent Principal Investigator: LAUREANO, Marissa

Co-Investigator(s) / Trainee: KHANDELWAL, Aditi, HASPEL, Richard, FUNG, Mark, LANE, Shannon, ZELLER, Michelle
BloodTechNet Award Program 8524.0
PID (Primary Immune Deficiency) Toolkit App Principal Investigator: DARNEL, Susanna

Co-Investigator(s) / Trainee: LI, Cecilia, BEAUCHAMP, Aimee, MORRISON, Doug, DALLAS, Karen, MICHAAN, Jack, TAVASZI, Alina, DENESIN, Pam, FUNG, Rene, British Columbia Primary Immune Deficiency (PID) Group Members
BloodTechNet Award Program 25000.0
An interactive virtual tour of blood product manufacturing at Canadian Blood Services Principal Investigator: BODNAR, Melanie

Co-Investigator(s) / Trainee: CHARGÉ, Sophie, YAN, Mathew, ABE, Tricia, TORDON, Bryan, CLARKE, Gwen
BloodTechNet Award Program 20000.0
An innovative digital strategy for dissemination of Choosing Wisely Canada guidelines in transfusion medicine Principal Investigator: CAMPBELL, Clinton

Co-Investigator(s) / Trainee: LABRECQUE, Suzanne, LABELLE, Peter, AL-JEDANI, Hanadi, SADEK, Irene, KAHWASH, Eiad
BloodTechNet Award Program 25000.0
Addressing racial disparity in blood, stem cell, and organ and tissue donor pools Principal Investigator: FINGRUT, Warren

Co-Investigator(s) / Trainee: OKONOFUA, Sylvia, YAN, Matthew, KHANDELWAL, Aditi, PENDERGRAST, Jacob, LEEIES, Murdoch, TINGA, Biba, HAW, Jennie, JAGELAVICIUTE, Gabriela, ROSENFELD, Aaron, KHANOLKAR, Rutvij, SEGALL, Romy, BELLINI, Jonathan, MORAKINYO, Tobi, AGYEPONG, Revée
BloodTechNet Award Program 34150.0
Stem Cell Transplantation Multimedia Toolkit Principal Investigator: FINGRUT, Warren

Co-Investigator(s) / Trainee: ALLAN, David, MESSNER, Hans, PETRASZKO, Tanya, ZUCCHET, Alyssa, DONNELLY, Sarah, HAMM, Taylor, THATCHER, Alicia, LADD, Aedan, CHAN, Sam, SUPPIAH, Roopa, WINQUIST, Lauren, LAU, Janny, PIETROBAN, Adam, LONDON, Sydney, COLES, Jenna
BloodTechNet Award Program 2000.0
Developing educational tools and resources to improve living donor care Principal Investigator: SANDAL, Shaifali

Co-Investigator(s) / Trainee: NUGUS, Peter, FORTIN, Marie-Chantal, LOBAN, Katya, BUGEJA, Ann, MAINRA, Rahul, DIPCHAND, Christine, BADENOCH, Heather
BloodTechNet Award Program 50000.0