Our Funded Research Projects

Updated April 2024

Title Principal Investigator / Supervisor Program Project Start Date Project End Date Sort ascending Total $ Awarded
A longitudinal analysis of behavioural and biological risk among men who have sex with men in metro Vancouver Principal Investigator: LACHOWSKY, Nathan

Co-Investigator(s) / Trainee: HOGG, Robert, MOORE, David, ROTH, Eric, ARMSTRONG, Heather
MSM Research Grant Program 50000.0
Examining the relationship between repeated blood donations in female donors on maternal/neonatal outcomes: a cohort study Principal Investigator: TINMOUTH, Alan

Co-Investigator(s) / Trainee: CHASSE, Michael, FERGUSSON, Dean A., GOLDMAN, Mindy R., O'BRIEN, Sheila F., SPRAGUE, Ann, van WALRAVEN, Carl, WALKER, Mark C., WILSON, Kumanan
Canadian Blood Services-CIHR Partnership Operating Grant Program 135657.0
Polymer-based manufacturing tolerogenic miRNA-based therapeutics Principal Investigator: SCOTT, Mark

Co-Investigator(s) / Trainee: HORWITZ, Marc S.
Canadian Blood Services-CIHR Partnership Operating Grant Program 491125.0
Stem Cell Transplantation Multimedia Toolkit Principal Investigator: FINGRUT, Warren

Co-Investigator(s) / Trainee: ALLAN, David, MESSNER, Hans, PETRASZKO, Tanya, ZUCCHET, Alyssa, DONNELLY, Sarah, HAMM, Taylor, THATCHER, Alicia, LADD, Aedan, CHAN, Sam, SUPPIAH, Roopa, WINQUIST, Lauren, LAU, Janny, PIETROBAN, Adam, LONDON, Sydney, COLES, Jenna
BloodTechNet Award Program 2000.0
Better blood transfusion - Phase two Principal Investigator: O'REILLY, Clare

Co-Investigator(s) / Trainee: PARKE, Graham, MORRISON, Douglas, CHIPPERFIELD, Kate, EVELEIGH, Shari, WILSON, Sophie
BloodTechNet Award Program 5250.0
Small molecule ice recrystallization inhibitors as cryo-additives for red blood cell cryopreservation Principal Investigator: BEN, Robert

Co-Investigator(s) / Trainee: POISSON, Jessica
Graduate Fellowship Program 82000.0
Impact of storage on the function of cord blood hematopoietic stem and progenitor cells Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: JAHAN, Suria
Graduate Fellowship Program 104000.0
Feasibility in Canada for a non-invasive prenatal testing using single-exon fetal RHD determination Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: CLARKE, Gwen, BHATTI, Aniqa
Blood Efficiency Accelerator Program 20000.0
Anti-GPIb mediated thrombocytopenia: implications for IVIG and other therapies Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee: XU, Miao
Graduate Fellowship Program 52000.0
Mathematical modeling - comparing HIV risk between MSM donation strategies Principal Investigator: O'BRIEN, Sheila

Co-Investigator(s) / Trainee: GRÉGOIRE, Yves, SEED, Clive, CUSTER, Brian, STEELE, Whitney, DAVISON, Katy, PILLONEL, Josiane
MSM Research Grant Program 18000.0
Role of blood component manufacturing on microvesicle-induced transfusion-related immune modulation Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: HOLOVATI, Jelena, BRANCH, Donald, ZHANG, Haibo
Intramural Research Grant Program 250660.0
Social media for knowledge translation and education 3 (SoMe-KTE3): Transfusion, thrombosis, and hemostasis Principal Investigator: SHIH, Andrew

Co-Investigator(s) / Trainee: CHAN, Teresa, DE WIT, Kristin, BHAGIRATH, Vinai, YEH, Calvin, CASTELLUCI, Lana, ELAHIE, Allahna, HEDDLE, Nancy, THOMA, Brent
BloodTechNet Award Program 30000.0
Podcast for FNAIT and ICTMG red cell specifications for hemoglobinopathies guidelines Principal Investigator: SHEHATA, Nadine

Co-Investigator(s) / Trainee:
BloodTechNet Award Program 6200.0
Monoclonal antibodies with anti-D-like activity in the amelioration of murine immune thrombocytopenia (ITP) Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: SEMPLE, John W., NI, Heyu
Intramural Research Grant Program 400000.0
Organ donation in Canada: Engaging with stakeholders and proposing solutions to current legal and ethical challenges Principal Investigator: GRUBEN, Vanessa

Co-Investigator(s) / Trainee:
James Kreppner Fellowship Program 150000.0
Understanding transcriptional and epigenetic control by Gfi1b towards the development of a therapy for sickle cell disease Principal Investigator: TRUDEL, Marie

Co-Investigator(s) / Trainee: MOROY, Tarik
Canadian Blood Services-CIHR Partnership Operating Grant Program 453132.0
Microfluidic devices to measure the deformability of stored red blood cells Principal Investigator: MA, Hongshen

Co-Investigator(s) / Trainee: SCOTT, Mark D.
Canadian Blood Services-CIHR Partnership Operating Grant Program 398301.0
Mechanisms of antibody-independent transfusion-related acute lung injury (TRALI) Principal Investigator: KUEBLER, Wolfgang

Co-Investigator(s) / Trainee: SEMPLE, John W.
Canadian Blood Services-CIHR Partnership Operating Grant Program 328712.0
Improving pathogen inactivation: the dengue virus-induced platelet proteome Principal Investigator: PRYZDIAL, Ed

Co-Investigator(s) / Trainee: TEGEGN, Tseday Zewdu
Graduate Fellowship Program 104000.0
DNA aptamers for detection of red blood cells destined for rapid post-transfusion clearance Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: DONKOR, David
Postdoctoral Fellowship Program 150000.0
Aneurysmal SubArachnoid Hemorrhage - Red blood cell transfusion And outcome (SAHaRA): a pilot randomized controlled trial Principal Investigator: ENGLISH, Shane

Co-Investigator(s) / Trainee: McINTYRE, Lauralyn A. , ALGIRD, Almunder , BOUTIN, Amélie , CHASSE, Michael , DOWLATSHAHI, Dariush , FERGUSSON, Dean A. , GRIESDALE, Donald , KRAMER, Andreas H. , LAUZIER, François , LUM, Cheemun , MARSHALL, Shawn C. , PAGLIARELLO, Giuseppe , SINCLAIR, John , TINMOUTH, Alan T. , TURGEON, Alexis F.
Canadian Blood Services-CIHR Partnership Operating Grant Program 157172.0
Defining disease mechanisms in Immune Thrombocytopenia (ITP) and their association with clinical outcomes Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee: COOK, Richard J., NAZY, Ishac
Canadian Blood Services-CIHR Partnership Operating Grant Program 317469.0
Identification of host cellular immune mechanisms responsible for the initiation and/or modulation of Transfusion Related Acute Lung Injury (TRALI) Principal Investigator: SEMPLE, John

Co-Investigator(s) / Trainee: KUEBLER, Wolfgang M.
Canadian Blood Services-CIHR Partnership Operating Grant Program 398982.0
Myocardial Ischemia and Transfusion. The MINT rollover trial Principal Investigator: HEBERT, Paul

Co-Investigator(s) / Trainee: CARSON, Jeffrey L., DEVEREAUX, Philip J., EIKELBOOM, John W., FERGUSSON, Dean A., GOODMAN, Shaun G. , MCALISTER, Finlay A. , TINMOUTH, Alan T.
Canadian Blood Services-CIHR Partnership Operating Grant Program 140210.0
Developing a Canadian policy on the responsible use of umbilical cord blood for proven indications in regenerative therapy Principal Investigator: ALLAN, David

Co-Investigator(s) / Trainee: HUTTON, Brian, CAULFIELD, Timothy
Kenneth J. Fyke Award Program 100000.0
PID (Primary Immune Deficiency) Toolkit App Principal Investigator: DARNEL, Susanna

Co-Investigator(s) / Trainee: LI, Cecilia, BEAUCHAMP, Aimee, MORRISON, Doug, DALLAS, Karen, MICHAAN, Jack, TAVASZI, Alina, DENESIN, Pam, FUNG, Rene, British Columbia Primary Immune Deficiency (PID) Group Members
BloodTechNet Award Program 25000.0
An innovative digital strategy for dissemination of Choosing Wisely Canada guidelines in transfusion medicine Principal Investigator: CAMPBELL, Clinton

Co-Investigator(s) / Trainee: LABRECQUE, Suzanne, LABELLE, Peter, AL-JEDANI, Hanadi, SADEK, Irene, KAHWASH, Eiad
BloodTechNet Award Program 25000.0
Polyhemoglobin catalase superoxide dismutase carbonic anhydrase: a novel soluble biotherapeutic with no cardiac toxicity for hemorrhagic shock and other uses Principal Investigator: CHANG, Thomas

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership Operating Grant Program 224520.0
Studying and alleviating the effects of platelet microparticles induced by pathogen reduction of platelet concentrates Principal Investigator: PROVOST, Patrick

Co-Investigator(s) / Trainee: LAUGIER, Jonathan
Graduate Fellowship Program 52000.0
Release, delivery and cell programming effects of platelet microparticles and microRNAs Principal Investigator: PROVOST, Patrick

Co-Investigator(s) / Trainee: BOILARD, Eric
Canadian Blood Services-CIHR Partnership Operating Grant Program 427422.0
Characterization of the hematopoietic reconstitution enhancing activity of osteoblasts derived from human mesenchymal stromal cells Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: CAMPBELL, Pearl , GARNIER, Alain
Canadian Blood Services-CIHR Partnership Operating Grant Program 320504.0
The Canadian National Transplant Research Program: increasing donating and improving transplantation outcomes Principal Investigator: WEST, Lori

Co-Investigator(s) / Trainee:
Transplantation Research Program 250000.0
Understanding the factors that influence bacterial proliferation and biofilm formation in platelet concentrates Principal Investigator: RAMIREZ-ARCOS, Sandra

Co-Investigator(s) / Trainee: LOZA CORREA, Maria
Postdoctoral Fellowship Program 151800.0
Transfusion options in coagulopathy: Efficacy in controlling bleeding Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: QADRI, Syed
Postdoctoral Fellowship Program 151800.0
Data sharing with CBMTG registry Principal Investigator: ALLAN, David

Co-Investigator(s) / Trainee: PAULSON, Kristjan
Small Project Funding Program 15000.0
Elucidation of the mechanism of IVIG-associated hemolysis Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: PENDERGRAST, Jacob , CSERTI-GAZDEWICH, Christine , SHEHATA, Nadine , PAVENSKI, Katerina , LAU, Wendy , CALLUM, Jeannie , LIN, Yulia , LIEBERMAN, Lani , HANNACH, Barbara
Intramural Research Grant Program 393712.0
Pathogenesis and treatment of immune thrombocytopenia: Are there fundamental differences between anti-GPlba- and anti-GPllbllla-mediated thrombocytopenia? Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership Operating Grant Program 378529.0
Design and implementation of circulatory oxygen therapeutics derived from human hemoglobin by improved systematic chemical coupling and cross-linking Principal Investigator: KLUGER, Ronald

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership Operating Grant Program 192039.0
Neonatal outcomes after transfusion of ABO non-identical blood (Neo-ABO) Principal Investigator: SOLH, Ziad

Co-Investigator(s) / Trainee: HEDDLE, Nancy, COOK, Richard J., FUSCH, Christoph
Small Project Funding Program 14988.7
Pre-transfusion furosemide for TACO Principal Investigator: SKEATE, Robert

Co-Investigator(s) / Trainee: CALLUM, Jeannie
Small Project Funding Program 15000.0
ROTEM-guided transfusion protocols - impact on the manufacturer Principal Investigator: TRUDEAU, Jacqueline

Co-Investigator(s) / Trainee: PETRASZKO, Tanya, LI, Cecilia
Small Project Funding Program 15000.0
University of Ottawa Centre for Transfusion Research Principal Investigator: TINMOUTH, Alan

Co-Investigator(s) / Trainee:
Program Support Award for Canadian Transfusion Medicine and Science Research Program 799887.8
The Centre for Blood Research Principal Investigator: CONWAY, Ed

Co-Investigator(s) / Trainee:
Program Support Award for Canadian Transfusion Medicine and Science Research Program 776229.0
McMaster Transfusion Research Program Principal Investigator: HEDDLE, Nancy

Co-Investigator(s) / Trainee:
Program Support Award for Canadian Transfusion Medicine and Science Research Program 833333.0
Prospective observational study of organ deceased donor management in 3 ICUs - a pilot study (the DONATE pilot study) Principal Investigator: MEADE, Maureen

Co-Investigator(s) / Trainee: D'ARAGON, Frederick, RIBIC, Christine, SHARPE, Michael, BALL, Ian, WILLIAMSON, David, DHANANI, Sonny, HANNA, Steven
Kenneth J. Fyke Award Program 89555.1
Exploratory analyses to determine if method of donor blood processing affects outcome in transfused recipients Principal Investigator: HEDDLE, Nancy

Co-Investigator(s) / Trainee: ACKER, Jason P. , ARNOLD, Donald M. , COOK, Richard J. , EIKELBOOM, John W. , O'BRIEN, Sheila F. , WEBERT, Kathryn E.
Canadian Blood Services-CIHR Partnership Operating Grant Program 159878.0
Use of red blood cell antigen genotyping to assess RhD diversity in sickle cell disease patients Principal Investigator: SHIH, Andrew

Co-Investigator(s) / Trainee: BERARDI, Philip, CLARKE, Gwen, HANNON, Judith, HEDDLE, Nancy, VERHOVSEK, Madeleine
Small Project Funding Program 15000.0
Transfusion-related Epstein-Barr Virus (EBV) infection among allogeneic stem cell transplant pediatric recipients: A multicenter prospective cohort study (TREASuRE Study) Principal Investigator: TROTTIER, Helen

Co-Investigator(s) / Trainee: ALFIERI, Carolina , BUTEAU, Chantal , DUVAL, Michel , LACROIX, Jacques , ROBITAILLE, Nancy , SPINELLA, Philip , TUCCI, Marisa
Canadian Blood Services-CIHR Partnership Operating Grant Program 519766.0
The Stem Cell Club: educating medical and nursing students to develop professional skills Principal Investigator: FINGRUT, Warren

Co-Investigator(s) / Trainee:
BloodTechNet Award Program 24458.0
MRI guided focused ultrasound facilitated IVIg immunotherapy as a therapeutic approach for Alzheimer's disease Principal Investigator: AUBERT, Isabelle

Co-Investigator(s) / Trainee: DUBEY, Sonam
Graduate Fellowship Program 100000.0