Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Microfluidic approach to genotyping human platelet antigens Lim C, Manage DP, Atrazhev A, Denomme G, Backhouse CJ, Acker JP 2012 IET Nanobiotechnol View Researchers New or improved product or process
Microfluidic analysis of red blood cell deformability as a means to assess hemin-induced oxidative stress resulting from Plasmodium falciparum intraerythrocytic parasitism Matthews K, Duffy SP, Myrand-Lapierre M-E, Ang RR, Li L, Scott MD, Ma H 2017 Integr Biol View Researchers Basic research
Microfluidic determination of lymphocyte vascular deformability: effects of intracellular complexity and early immune activation Kang N, Guo Q, Islamzada E, Ma H, Scott MD 2018 Integr Biol View Researchers Basic research
Microfluidic analysis of red blood cell deformability Guo Q, Duffy SP, Matthews K, Santoso AT, Scott MD, Ma H 2014 J Biomech View Researchers Basic research
Microfluidic deformability analysis of the red cell storage lesion Matthews K, Myrand-Lapierre M-E, Ang RR, Duffy SP, Scott MD, Ma H 2015 J Biomech View Researchers New or improved product or process
Characterizing Frailty In Myeloproliferative Neoplasms: results from the ORCHID study Chornenki NLJ, Siegal DM, Qamar K, Woolgar S, Rangarajan S, Karampatos S, Leong DP, Hillis CM 2022 Leuk Res View Researchers Clinical research
Mesenchymal stromal cells from patients with acute myeloid leukemia have altered capacity to expand differentiated hematopoietic progenitors Chandran P, Le Y, Li Y, Sabloff M, Mehic J, Rosu-Myles M, Allan DS 2015 Leuk Res View Researchers Basic research
Membrane Type-1 Matrix Metalloproteinase Expression in Acute Myeloid Leukemia and Its Upregulation by Tumor Necrosis Factor-? Marquez-Curtis LA, Shirvaikar N, Turner AR, Mirza I, Surmawala A, Larratt LM, Janowska-Wieczorek A 2012 Cancers View Researchers Basic research
Mechanism of hemoglobin-induced cellular injury in desiccated red blood cells Kanias T, Acker JP 2010 Free Radic Biol Med View Researchers Basic research
MDM2 antagonist nutlin plus proteasome inhibitor velcade combination displays a synergistic anti-myeloma activity Saha MN, Jiang H, Jayakar J, Reece D, Branch DR, Chang H 2010 Cancer Biol Ther View Researchers Basic research
Risk-assessment models for VTE and bleeding in hospitalized medical patients: an overview of systematic reviews Darzi AJ, Repp AB, Spencer FA, Morsi RZ, Charide R, Etxeandia-Ikobaltzeta I, Bauer KA, Burnett AE, Cushman M, Dentali F, Kahn SR, Rezende SM, Zakai NA, Agarwal A, Karam SG, Lotfi T, Wiercioch W, Waziry R, Iorio A, Akl EA, Schünemann HJ 2020 Blood Adv View Health care providers Clinical research
Misdiagnosis of primary immune thrombocytopenia and frequency of bleeding: lessons from the McMaster ITP Registry Arnold DM, Nazy I, Clare R, Jaffer AM, Aubie B, Li N, Kelton JG 2017 Blood Adv View Health care providers Clinical research
Stuttering priapism in a patient with sickle cell trait treated with automated red cell exchange transfusion Ebraheem MS, Verhovsek M 2021 Blood Adv View Health care providers Clinical research
Blood manufacturing methods affect red blood cell product characteristics and immunomodulatory activity of red blood cell products and charactersitics of extracellular vesicles. Almizraq RJ, Norris PJ, Inglis H, Menocha S, Wirtz MR, Juffermans N, Pandey S, Spinella PC, Acker JP, Muszynski JA 2018 Blood Adv View Researchers Basic research
The association of ABO blood group with indices of disease severity and multiorgan dysfunction in COVID-19 Hoiland RL, Fergusson NA, Mitra AR, Griesdale DEG, Devine DV, Stukas S, Cooper J, Thiara S, Foster D, Chen LYC, Lee AYY, Conway EM, Wellington CL, Sekhon MS 2020 Blood Adv View Health care providers Clinical research
Chemokines IP-10/CXCL10 and IL-8/CXCL8 are potential novel biomarkers of warm autoimmune hemolytic anemia Branch DR, Leger RM, Sakac d, Yi Q, Duong T, Yeung RSM, Binnington B, Bloch EM 2022 Blood Adv View Researchers Basic research
Systematic review and meta-analysis of outcomes in patients with suspected pulmonary embolism Patel P, Patel P, Bhatt M, Braun C, Begum H, Nieuwlaat R, Khatib R, Martins CC, Zhang Y, Etxeandia-Ikobaltzeta I, Varghese J, Alturkmani H, Bahaj W, Baig M, Kehar R, Mustafa A, Ponnapureddy R, Sethi A, Thomas M, Wooldridge D, Lim W, Bates SM, Lang E, Le Gal G, Haramati LB, Kline J, Righini M, Wiercioch W, Schünemann H, Mustafa RA 2021 Blood Adv View Researchers Clinical research
The clinical and laboratory diagnosis of vaccine-induced immune thrombotic thrombocytopenia Bissola AL, Daka M, Arnold DM, Smith JW, Moore JC, Clare R, Ivetic N, Kelton JG, Nazy I 2022 Blood Adv View Researchers Clinical research
Platelet autoantibodies in the bone marrow of patients with immune thrombocytopenia Shrestha S, Nazy I, Smith JW, Kelton JG, Arnold DM 2020 Blood Adv View Health care providers Clinical research
American Society of Hematology 2019 guidelines for sickle cell disease: cardiopulmonary and kidney disease Liem RI, Lanzkron S, T DC, DeCastro L, Desai AA, Ataga KI, Cohen RT, Haynes J, Osunkwo I, Lebensburger JD, Lash JP, Wun T, Verhovsek M, Ontala E, Blaylark R, Alahdab F, Katabi A, Mustafa RA 2019 Blood Adv View Health care providers Benchmarking and standard setting
American Society of Hematology 2018 guidelines for management of venous thromboembolism: heparin-induced thrombocytopenia. Cuker A AG, Chong BH, Cines DB, Greinacher A, Gruel Y, Linkins LA, Rodner SB, Selleng S, Warkentin TE, Wex A, Mustafa RA, Morgan RL, Santesso N 2018 Blood Adv View Health care providers Benchmarking and standard setting
Management of heparin-induced thrombocytopenia: systematic reviews and meta-analyses Morgan RL, Ashoorion V, Cuker A, Begum H, Ross S, Martinez N, Chong BH, Linkins LA, Warkentin TE, Wiercioch W, Nieuwlaat R, Schünemann H, Santesso N 2020 Blood Adv View Researchers Clinical research
A systematic review of the association between anti-?-2 glycoprotein I antibodies and APS manifestations Jiang D, Lim W, Crowther M, Garcia D 2021 Blood Adv View Researchers Clinical research
Genome-wide association study of platelet factor 4/heparin antibodies in heparin-induced thrombocytopenia Giles JB, Steiner HE, Rollin J, Shaffer CM, Momozawa Y, Mushiroda T, Inai C, Selleng K, Thiele T, Pouplard C, Heddle NM, Kubo M, Miller EC, Martinez KL, Phillips EJ, Warkentin TE, Gruel Y, Greinacher A, Roden DM, Karnes JH 2022 Blood Adv View Researchers Basic research
American Society of Hematology 2021 guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19 Cuker A, Tseng EK, Nieuwlaat R, Angchaisuksiri P, Blair C, Dane K, Davila J, DeSancho MT, Diuguid D, Griffin DO, Kahn SR, Klok FA, Lee AI, Neumann I, Pai A, Pai M, Righini M, Sanfilippo KM, Siegal D, Skara M, Touri K, E AA, Bou Akl I, Boulos M, Brignardello-Petersen R, Charide R, Chan M, Dearness K, Darzi AJ, Kolb P, Colunga-Lozano LE, Mansour R, Morgano GP, Morsi RZ, Noori A, Piggott T, Qiu Y, Roldan Y, Schünemann F, Stevens A, Solo K, Ventresca M, Wiercioch W, Mustafa RA, Schünemann HJ 2021 Blood Adv View Health care providers Benchmarking and standard setting
A user guide to the American Society of Hematology clinical practice guidelines Izcovich A, Cuker A, Kunkle R, Neumann I, Panepinto J, Pai M, Seftel M, Cheung MC, Lottenberg R, Byrne M, Plovnick R, Terrell D, Holter-Chakrabarty JL, Djulbegovic B, Hicks LK, Wiercioch W, Nieuwlaat R, Schünemann HJ 2020 Blood Adv View Health care providers Benchmarking and standard setting
Mature murine megakaryocytes present antigen-MHC class I molecules to T cells and transfer them to platelets Zufferey A, Speck ER, Machlus KR, Aslam R, Guo L, McVey MJ, Kim M, Kapur R, Boilard E, Italiano JE, Jr., Semple JW 2017 Blood Adv View Researchers Basic research
Characteristics of VITT antibodies in patients vaccinated with Ad26.COV2.S Huynh A, Arnold DM, Michael JV, Clare R, Smith JW, Daka M, Ianosi-Irimie M, McKenzie SE, Kelton JG, Nazy I 2023 Blood Adv View Researchers Clinical research
Donor-recipient sex is associated with transfusion-related outcomes in critically ill patients Alshalani A, Uhel F, Cremer OL, Schultz MJ, de Vooght KMK, van Bruggen R, Acker JP, Juffermans NP, on behalf of the MARS Consortium 2022 Blood Adv View Researchers Clinical research
Donor-recipient sex is associated with transfusion-related outcomes in critically ill patients Alshalani A, Uhel F, Cremer OL, Schultz MJ, de Vooght KMK, van Bruggen R, Acker JP, Juffermans NP 2022 Blood Adv View Researchers Clinical research
SARS-CoV-2 spike-dependent platelet activation in COVID-19 vaccine-induced thrombocytopenia Appelbaum J, Arnold DM, Kelton JG, Gernsheimer T, Jevtic SD, Ivetic N, Smith JW, Nazy I 2022 Blood Adv View Researchers Basic research
Fetal/neonatal alloimmune thrombocytopenia: a systematic review of impact of HLA-DRB3*01:01 on fetal/neonatal outcome Kjeldsen-Kragh J, Fergusson DA, Kjaer M, Lieberman L, Greinacher A, Murphy MF, Bussel J, Bakchoul T, Corke S, Bertrand G, Oepkes D, Baker JM, Hume H, Massey E, Kaplan C, Arnold DM, Baidya S, Ryan G, Savoia HF, Landry D, Shehata N 2020 Blood Adv View Health care providers Clinical research
Cost-effectiveness of eltrombopag vs intravenous immunoglobulin for the perioperative management of immune thrombocytopenia Kaur MN, Arnold DM, Heddle NM, Cook RJ, Hsia C, Blostein M, Jamula E, Sholzberg M, Lin Y, Kassis J, Larratt L, Tinmouth A, Carruthers J, Li N, Liu Y, Xie F 2022 Blood Adv View Health care providers Clinical research
N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice Chen J, Reheman A, Gushiken FC, Nolasco L, Fu X, Moake JL, Ni H, Lopez JA 2011 J Clin Invest View Researchers Basic research
Maternal anti-platelet beta-3 integrins impair angiogenesis and cause intracranial hemorrhage Yougbaré I, Lang S, Yang H, Chen P, Zhao X, Tai W-S, Zdravic D, Vadasz B, Li C, Piran S, Marshall A, Zhu G, Tiller H, Killie MK, Boyd S, Leong-Poi H, Wen X-Y, Skogen B, Adamson SL, Freedman J, Ni H 2015 J Clin Invest View Researchers Basic research
The maternal immune response to fetal platelet GPIb? causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies Li C, Piran S, Chen P, Lang S, Zarpellon A, Jin JW, Zhu G, Reheman A, van der Wal DE, Simpson EK, Ni R, Gross PL, Ware J, Ruggeri ZM, Freedman J, Ni H 2011 J Clin Invest View Researchers Basic research
Plasma fibronectin supports hemostasis and regulates thrombosis Wang Y, Reheman A, Spring CM, Kalantari J, Marshall AH, Wolberg AS, Gross PL, Weitz JI, Rand ML, Mosher DF, Freedman J, Ni H 2014 J Clin Invest View Researchers Basic research
Management of immune-mediated thrombocytopenia Arnold DM, Nazi I, Smith JW, Warkentin TE 2016 Rossi's Principles of Transfusion Medicine View Health care providers Clinical research
Plasma and cryoprecipitate for transfusion Stanworth SJ, Tinmouth AT 2016 Rossi's Principles of Transfusion Medicine View Researchers Basic research
Bacterial contamination of blood components Bloch EM, Benjamin RJ, Ramirez-Arcos S 2022 Rossi's Principles of Transfusion Medicine View Health care providers Benchmarking and standard setting
Management of immune‐mediated thrombocytopenia Gabe C, Arnold D, Smith J, T W 2022 Rossi's Principles of Transfusion Medicine View Health care providers Benchmarking and standard setting
Low-intensity pulsed ultrasound-mediated stimulation of hematopoietic stem/progenitor cell viability, proliferation and differentiation in vitro Xu P, Gul-Uludag H, Ang WT, Yang X, Huang M, Marquez-Curtis L, McGann L, Janowska-Wieczorek A, Xing J, Swanson E, Chen J 2012 Biotechnol Lett View Researchers Basic research
A multisite study of pertussis vaccine effectiveness by time since last vaccine dose from three Canadian provinces: A Canadian Immunization Research Network study Savage RD, Bell CA, Righolt CH, Wilkinson K, Schwartz KL, Chen C, Bolotin S, Deeks SL, Drews SJ, Jamieson FB, Johnson C, Kwong JC, Mahmud SM, Russell ML, Simmonds KA, Svenson LW, Crowcroft NS 2021 Vaccine View Researchers Clinical research
Low pertussis toxin antibody levels in two regional cohorts of Canadian pregnant women Bigham M, Konrad S, Van Buynder P, Van Buynder J, Isaac-Renton J, ElSherif M, Halperin SA 2014 Vaccine View Health care providers Clinical research
Vaccine-induced immune thrombotic thrombocytopenia after COVID-19 vaccination: Description of a series of 39 cases in Brazil Mouta Nunes de Oliveira P, Mendes-de-Almeida DP, Bertollo Gomes Porto V, Crespo Cordeiro C, Vitiello Teixeira G, Saraiva Pedro R, Roberto Gomes Takey P, Kegele Lignani L, Reis Xavier J, Cardoso Doria da Gama V, Amorim Filho L, Emoingt Furtado B, Santa Maria A, Dahrug Barros T, Neves Waite Freitas L, Dos Santos Pereira T, Lima Abreu D, Bernardes Ramos M, Gabe C, Arnold D, William Smith J, Nazy I, Lourdes de Sousa Maia M 2022 Vaccine View Health care providers Clinical research
Pertussis vaccine effectiveness in a frequency matched population-based case-control Canadian Immunization Research Network study in Ontario, Canada 2009–2015 Crowcroft NS, Schwartz KL, Chen C, Johnson C, Li Y, Marchand-Austin A, Bolotin S, Jamieson FB, Drews SJ, Russell ML, Svenson LW, Simmonds K, Mahmud SM, Kwong JC 2019 Vaccine View Researchers Clinical research
Acellular pertussis vaccine effectiveness and waning immunity in Alberta, Canada: 2010–2015, a Canadian Immunization Research Network (CIRN) study Bell CA, Russell ML, Drews SJ, Simmonds KA, Svenson LW, Schwartz KL, Kwong JC, Mahmud SM, Crowcroft NS 2019 Vaccine View Health care providers Clinical research
Low levels of interleukin-10 in patients with transfusion-related acute lung injury Kapur R, Kim M, Rebetz J, Rondina MT, Porcelijn L, Semple JW 2017 Ann Transl Med View Researchers Clinical research
Long-term graft function following autologous hematopoietic cell transplantation and the impact of preemptive plerixafor in predicted poor mobilizers Visram A, Bredeson C, Allan D, Sabloff M, Huebsch L, Tay J, Kekre N, McDiarmid S, Mallick R, Tinmouth A, Martin L, Hamelin L, Maze D 2018 Blood Cancer J View Health care providers Clinical research
Liposomes composed of unsaturated lipids for membrane modification of human erythrocytes Stoll C, Holovati JL, Acker JP, Wolkers WF 2011 Mol Membr Biol View Researchers Basic research