Our Research Publications
Updated November 2023
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Title | Authors | Year | Journal | Link to Article | Intended Audience Sort descending | Purpose |
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Healthcare provider knowledge, attitudes, beliefs, and practices surrounding the prescription of opioids for chronic non-cancer pain in North America: protocol for a mixed-method systematic review | Rash JA, Buckley N, Busse JW, Campbell TS, Corace K, Cooper L, Flusk D, Iorio A, Lavoie KL, Poulin PA, Skidmore B | 2018 | Systematic Reviews | View Healthcare provider knowledge, attitudes, beliefs, and practices surrounding the prescription of opioids for chronic non-cancer pain in North America: protocol for a mixed-method systematic review | Researchers | Clinical research |
Activated thrombin-activatable fibrinolysis inhibitor (TAFIa) attenuates fibrin-dependent plasmin generation on thrombin-activated platelets | Ni R, Neves MAD, Wu C, Cerroni SE, Flick MJ, Ni H, Weitz JI, Gross PL, Kim PY | 2020 | Thromb Haemost | View Activated thrombin-activatable fibrinolysis inhibitor (TAFIa) attenuates fibrin-dependent plasmin generation on thrombin-activated platelets | Researchers | Basic research |
Challenges and key lessons from the design and implementation of an international haemophilia registry supported by a pharmaceutical company | Hay CRM, Shima M, Makris M, Jiménez-Yuste V, Oldenburg J, Fischer K, Iorio A, Skinner MW, Santagostino E, von Mackensen S, Kessler CM | 2020 | Haemophilia | View Challenges and key lessons from the design and implementation of an international haemophilia registry supported by a pharmaceutical company | Researchers | Clinical research |
Evaluation of riboflavin and ultraviolet light treatment against Klebsiella pneumoniae in whole blood-derived platelets: A pilot study | Alabdullatif M, Osman IE, Alrasheed M, Ramirez-Arcos S, Alyousef M, Althawadi S, Alhumiadan H | 2021 | Transfusion | View Evaluation of riboflavin and ultraviolet light treatment against Klebsiella pneumoniae in whole blood-derived platelets: A pilot study | Researchers | New or improved product or process |
Inhibition of platelet phagocytosis as an in vitro predictor for therapeutic potential of RBC antibodies in murine ITP | Khan R, Menard M, Jen C-C, Chen X, Norris PAA, Lazarus AH | 2020 | Blood | View Inhibition of platelet phagocytosis as an in vitro predictor for therapeutic potential of RBC antibodies in murine ITP | Researchers | Basic research |
Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients | Isho B, Abe KT, Zuo M, Jamal AJ, Rathod B, Wang JH, Li Z, Chao G, Rojas OL, Bang YM, Pu A, Christie-Holmes N, Gervais C, Ceccarelli D, Samavarchi-Tehrani P, Guvenc F, Budylowski P, Li A, Paterson A, Yue FY, Marin LM, Caldwell L, Wrana JL, Colwill K, Sicheri F, Mubareka S, Gray-Owen SD, Drews SJ, Siqueira WL, Barrios-Rodiles M, Ostrowski M, Rini JM, Durocher Y, McGeer AJ, Gommerman JL, Gingras AC | 2020 | Sci Immunol | View Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients | Researchers | Clinical research |
A trend of dropping anti-SARS-CoV-2 plaque reduction neutralization test titers over time in Canadian convalescent plasma donors | Drews SJ, Devine DV, McManus J, Mendoza E, Manguiat K, Wood H, Girardin R, Dupuis A, McDonough K, Drebot M | 2021 | Transfusion | View A trend of dropping anti-SARS-CoV-2 plaque reduction neutralization test titers over time in Canadian convalescent plasma donors | Researchers | Basic research |
T cell-mediated autoimmunity in immune thrombocytopenia | Vrbensky JR, Nazy I, Clare R, Larché M, Arnold DM | 2022 | Eur J Haematol | View T cell-mediated autoimmunity in immune thrombocytopenia | Researchers | Clinical research |
Recommended primary outcomes for clinical trials evaluating hemostatic blood products and agents in patients with bleeding: Proceedings of a National Heart Lung and Blood Institute and US Department of Defense Consensus Conference | Spinella PC, El Kassar N, Cap AP, Kindzelski AL, Almond CS, Barkun A, Gernsheimer TB, Goldstein JN, Holcomb JB, Iorio A, Jensen DM, Key NS, Levy JH, Mayer SA, Moore EE, Stanworth SJ, Lewis RJ, Steiner ME | 2021 | J Trauma Acute Care Surg | View Recommended primary outcomes for clinical trials evaluating hemostatic blood products and agents in patients with bleeding: Proceedings of a National Heart Lung and Blood Institute and US Department of Defense Consensus Conference | Researchers | Benchmarking and standard setting |
Discrete-Event Simulation to Model the Thrombolysis Process for Acute Ischemic Stroke Patients at Urban and Rural Hospitals | Bulmer T, Volders D, Blake J, Kamal N | 2021 | Front Neurol | View Discrete-Event Simulation to Model the Thrombolysis Process for Acute Ischemic Stroke Patients at Urban and Rural Hospitals | Researchers | New or improved product or process |
Impact of cardiopulmonary bypass duration on efficacy of fibrinogen replacement with cryoprecipitate compared with fibrinogen concentrate: a <em>post hoc</em> analysis of the Fibrinogen Replenishment in Surgery (FIBRES) randomised controlled trial | Bartoszko J, Martinez-Perez S, Callum J, Karkouti K, Farouh ME, Scales DC, Heddle NM, Crowther M, Rao V, Hucke H-P, Carroll J, Grewal D, Brar S, Brussières J, Grocott H, Harle C, Pavenski K, Rochon A, Saha T, Shepherd L, Syed S, Tran D, Wong D, Zeller M | 2022 | Br J Anaesth | View Impact of cardiopulmonary bypass duration on efficacy of fibrinogen replacement with cryoprecipitate compared with fibrinogen concentrate: a <em>post hoc</em> analysis of the Fibrinogen Replenishment in Surgery (FIBRES) randomised controlled trial | Researchers | Clinical research |
Evaluation of the performance of multiple immunoassay diagnostic platforms on the National Microbiology Laboratory SARS-CoV-2 National Serology Panel | Dibernardo A, Toledo NP, Robinson A, Osiowy C, Giles E, Day J, Lindsay LR, Drebot MA, Booth TF, Pidduck T, Baily A, Charlton CL, Tipples G, Kanji JN, Brochu G, Lang A, Therrien C, Bélanger-Collard M, Beaulac S-N, Gilfix BM, Boivin G, Hamelin M-È, Carbonneau J, Lévesque S, Martin P, Finzi A, Gendron-Lepage G, Goyette G, Benlarbi M, Gasser R, Fortin C, Martel-Lafferrière V, Lavoie M, Guérin R, Haraoui L-P, Renaud C, Jenkins C, O'Brien SF, Drews SJ, Conrod V, Tran V, Awrey B, Scheuermann R, DuPuis A, Payne A, Warszycki C, Girardin R, Lee W, Zahariadis G, Jiao L, Needle R, Cordenbach J, Zaharatos J, Taylor K, Teltscher M, Miller M, Elsherif M, Robertson P, Robinson JL | 2022 | J Assoc Med Microbiol Infect Dis Can | View Evaluation of the performance of multiple immunoassay diagnostic platforms on the National Microbiology Laboratory SARS-CoV-2 National Serology Panel | Researchers | Benchmarking and standard setting |
The bending rigidity of the red blood cell cytoplasmic membrane | Himbert S, D’Alessandro A, Qadri SM, Majcher MJ, Hoare T, Sheffield WP, Nagao M, Nagle JF, Rheinstädter MC | 2022 | PLoS One | View The bending rigidity of the red blood cell cytoplasmic membrane | Researchers | Basic research |
Comparison of three dosing intervals for the primary vaccination of the SARS-CoV-2 mRNA Vaccine (BNT162b2) on magnitude, neutralization capacity and durability of the humoral immune response in health care workers: A prospective cohort study | Leong DP, Zhang A, Breznik JA, Clare R, Huynh A, Mushtaha M, Rangarajan S, Stacey H, Kim PY, Loeb M, Denburg JA, Mertz D, Chagla Z, Nazy I, Miller MS, Bowdish DME, Duong M | 2023 | PLoS One | View Comparison of three dosing intervals for the primary vaccination of the SARS-CoV-2 mRNA Vaccine (BNT162b2) on magnitude, neutralization capacity and durability of the humoral immune response in health care workers: A prospective cohort study | Researchers | Clinical research |
A Rapid Screening Assay Identifies Monotherapy with Interferon-ß and Combination Therapies with Nucleoside Analogs as Effective Inhibitors of Ebola Virus | McCarthy SDS, Majchrzak-Kita B, Racine T, Kozlowski HN, Baker DP, Hoenen T, Kobinger GP, Fish EN, Branch DR | 2016 | PLoS Negl Trop Dis | View A Rapid Screening Assay Identifies Monotherapy with Interferon-ß and Combination Therapies with Nucleoside Analogs as Effective Inhibitors of Ebola Virus | Researchers | Basic research |
Anthocyanin Extract from Black Rice Significantly Ameliorates Platelet Hyperactivity and Hypertriglyceridemia in Dyslipidemic Rats Induced by High Fat Diets | Yang Y, Andrews MC, Hu Y, Wang D, Qin Y, Zhu Y, Ni H, Ling W | 2011 | J Agric Food Chem | View Anthocyanin Extract from Black Rice Significantly Ameliorates Platelet Hyperactivity and Hypertriglyceridemia in Dyslipidemic Rats Induced by High Fat Diets | Researchers | Basic research |
Comparison of mammalian and bacterial expression library screening to detect recombinant alpha-1 proteinase inhibitor variants with enhanced thrombin inhibitory capacity? | Gierczak RF, Bhakta V, Xie M, Sheffield WP | 2015 | J Biotechnol | View Comparison of mammalian and bacterial expression library screening to detect recombinant alpha-1 proteinase inhibitor variants with enhanced thrombin inhibitory capacity? | Researchers | Basic research |
Deformability based sorting of red blood cells improves diagnostic sensitivity for malaria caused by Plasmodium falciparum | Guo Q, Duffy SP, Matthews K, Deng X, Santoso AT, Islamzada E, Ma H | 2016 | Lab Chip | View Deformability based sorting of red blood cells improves diagnostic sensitivity for malaria caused by Plasmodium falciparum | Researchers | New or improved product or process |
Factor XIIIa-dependent retention of red blood cells in clots is mediated by fibrin ?-chain crosslinking | Byrnes JR, Duval C, Wang Y, Hansen CE, Ahn B, Mooberry MJ, Clark MA, Johnsen JM, Lord ST, Lam W, Meijers JCM, Ni H, Ariens RAS, Wolberg AS | 2015 | Blood | View Factor XIIIa-dependent retention of red blood cells in clots is mediated by fibrin ?-chain crosslinking | Researchers | Basic research |
Human Neutrophil Peptides Mediate Endothelial-Monocyte Interaction, Foam Cell Formation, and Platelet Activation | Quinn KL, Henriques M, Tabuchi A, Han B, Yang H, Cheng W-E, Tole S, Yu H, Luo A, Charbonney E, Tullis E, Lazarus A, Robinson LA, Ni H, Peterson BR, Kuebler WM, Slutsky AS, Zhang H | 2011 | Arterioscler Thromb Vasc Biol | View Human Neutrophil Peptides Mediate Endothelial-Monocyte Interaction, Foam Cell Formation, and Platelet Activation | Researchers | Basic research |
Intracellular ice formation in confluent monolayers of human dental stem cells and membrane damage | Zhurova M, Woods EJ, Acker JP | 2010 | Cryobiology | View Intracellular ice formation in confluent monolayers of human dental stem cells and membrane damage | Researchers | Basic research |
Microfluidic analysis of red blood cell deformability | Guo Q, Duffy SP, Matthews K, Santoso AT, Scott MD, Ma H | 2014 | J Biomech | View Microfluidic analysis of red blood cell deformability | Researchers | Basic research |
Mouse Models of Autoimmune Diseases: Immune Thrombocytopenia | Neschadim A, Branch DR | 2015 | Current Pharmaceutical Design | View Mouse Models of Autoimmune Diseases: Immune Thrombocytopenia | Researchers | Basic research |
Osmotic tolerance limits of red blood cells from umbilical cord blood | Zhurova M, Lusianti RE, Higgins AZ, Acker JP | 2014 | Cryobiology | View Osmotic tolerance limits of red blood cells from umbilical cord blood | Researchers | Basic research |
Platelets, immune-mediated thrombocytopenias, and fetal hemorrhage | Xu XR, Gallant RC, Ni H | 2016 | Thromb Res | View Platelets, immune-mediated thrombocytopenias, and fetal hemorrhage | Researchers | Basic research |
Protein translation occurs in platelet concentrates despite riboflavin/UV light pathogen inactivation treatment | Schubert P, Culibrk B, Karwal S, Goodrich RP, Devine DV | 2016 | Proteomics Clin Appl | View Protein translation occurs in platelet concentrates despite riboflavin/UV light pathogen inactivation treatment | Researchers | Basic research |
The effect of processing method on the in vitro characteristics of red blood cell products | Hansen AL, Kurach JDR, Turner TR, Jenkins C, Busch MP, Norris PJ, Dugger J, Tomasulo PA, Devine DV, Acker JP | 2015 | Vox Sang | View The effect of processing method on the in vitro characteristics of red blood cell products | Researchers | Basic research |
The perioperative anticoagulant use for surgery evaluation (PAUSE) study for patients on a direct oral anticoagulant who need an elective surgery or procedure: design and rationale | Douketis JD, Spyropoulos AC, Anderson JM, Arnold DM, Bates SM, Blostein M, Carrier M, Caprini JA, Clark NP, Coppens M, Dentali F, Duncan J, Gross PL, Kassis J, Kowalski S, Lee AY, Le Gal G, Le Templier G, Li N, MacKay E, Shah V, Shivakumar S, Solymoss S, Spencer FA, Syed S, Tafur AJ, Vanassche T, Thiele T, Wu C, Yeo E, Schulman S | 2017 | Thromb Haemost | View The perioperative anticoagulant use for surgery evaluation (PAUSE) study for patients on a direct oral anticoagulant who need an elective surgery or procedure: design and rationale | Researchers | Clinical research |
Immunotherapy: the good, the bad, the ugly, and the really ugly | Branch DR | 2019 | Transfusion | View Immunotherapy: the good, the bad, the ugly, and the really ugly | Researchers | Clinical research |
An international external quality assessment for laboratory diagnosis of heparin-induced thrombocytopenia | Eekels JJM, Althaus K, Bakchoul T, Kroll H, Kiefel V, Nazy I, Lee LS, Sachs U, Warkentin TE, Greinacher A | 2019 | J Thromb Haemost | View An international external quality assessment for laboratory diagnosis of heparin-induced thrombocytopenia | Researchers | New or improved product or process |
Devices to Reduce the Volume of Blood Taken for Laboratory Testing in ICU Patients: A Systematic Review | Siegal DM, Manning N, Jackson Chornenki NL, Hillis CM, Heddle NM | 2018 | J Intensive Care Med | View Devices to Reduce the Volume of Blood Taken for Laboratory Testing in ICU Patients: A Systematic Review | Researchers | New or improved product or process |
Coenzyme Q10 attenuates platelet integrin alpha II beta 3 signaling and platelet hyper-reactivity in ApoE-deficient mice | Ya F, Xu XR, Tian Z, Gallant RC, Song F, Shi Y, Wu Y, Wan J, Zhao Y, Adili R, Ling W, Ni H, Yang Y | 2020 | Food Funct | View Coenzyme Q10 attenuates platelet integrin alpha II beta 3 signaling and platelet hyper-reactivity in ApoE-deficient mice | Researchers | Basic research |
Fc?RI and FC?RIII on splenic macrophages mediate phagocytosis of anti-glycoprotein IIb/III autoantibody-opsonized platelets in immune thrombocytopenia | Norris PAA, Segel GB, Burack WR, Sachs UJ, Lissenberg-Thunnissen SN, Vidarsson G, Bayat B, Cserti-Gazdewich CM, Callum J, Lin Y, Branch D, Kapur R, Semple JW, Lazarus AH | 2020 | Haematologica | View Fc?RI and FC?RIII on splenic macrophages mediate phagocytosis of anti-glycoprotein IIb/III autoantibody-opsonized platelets in immune thrombocytopenia | Researchers | Basic research |
Proceedings of the Food and Drug Administration public workshop on pathogen reduction technologies for blood safety 2018 | Atreya C, Glynn S, Busch M, Kleinman S, Snyder E, Rutter S, AuBuchon J, Flegel W, Reeve D, Devine D, Cohn C, Custer B, Goodrich R, Benjamin RJ, Razatos A, Cancelas J, Wagner S, Maclean M, Gelderman M, Cap A, Ness P | 2019 | Transfusion | View Proceedings of the Food and Drug Administration public workshop on pathogen reduction technologies for blood safety 2018 | Researchers | New or improved product or process |
Assessment of extracellular vesicles using IFC for application in transfusion medicine | Mykhailova O, Seghatchian J, Acker JP | 2020 | Transfus Apher Sci | View Assessment of extracellular vesicles using IFC for application in transfusion medicine | Researchers | Basic research |
Clinical use of Convalescent Plasma in the COVID-19 pandemic: a transfusion-focussed gap analysis with recommendations for future research priorities | Al-Riyami AZ, Schäfer R, van den Berg K, Bloch EM, Estcourt LJ, Goel R, Hindawi S, Josephson CD, Land K, McQuilten ZK, Spitalnik SL, Wood EM, Devine DV, So-Osman C | 2020 | Vox Sang | View Clinical use of Convalescent Plasma in the COVID-19 pandemic: a transfusion-focussed gap analysis with recommendations for future research priorities | Researchers | Clinical research |
Effect of cryopreservation on a rare McLeod donor red blood cell concentrate | Turner TR, Clarke G, Denomme GA, Skeate R, Acker JP | 2021 | Immunohematology | View Effect of cryopreservation on a rare McLeod donor red blood cell concentrate | Researchers | Basic research |
A multisite study of pertussis vaccine effectiveness by time since last vaccine dose from three Canadian provinces: A Canadian Immunization Research Network study | Savage RD, Bell CA, Righolt CH, Wilkinson K, Schwartz KL, Chen C, Bolotin S, Deeks SL, Drews SJ, Jamieson FB, Johnson C, Kwong JC, Mahmud SM, Russell ML, Simmonds KA, Svenson LW, Crowcroft NS | 2021 | Vaccine | View A multisite study of pertussis vaccine effectiveness by time since last vaccine dose from three Canadian provinces: A Canadian Immunization Research Network study | Researchers | Clinical research |
GPIb? is the driving force of hepatic thrombopoietin generation | Karakas D, Xu M, Ni H | 2021 | Res Pract Thromb Haem | View GPIb? is the driving force of hepatic thrombopoietin generation | Researchers | Basic research |
Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia | Greinacher A, Selleng K, Palankar R, Wesche J, Handtke S, Wolff M, Aurich K, Lalk M, Methling K, Völker U, Hentschker C, Michalik S, Steil L, Reder A, Schönborn L, Beer M, Franzke K, Büttner A, Fehse B, Stavrou EX, Rangaswamy C, Mailer RK, Englert H, Frye M, Thiele T, Kochanek S, Krutzke L, Siegerist F, Endlich N, Warkentin TE, Renné T | 2021 | Blood | View Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia | Researchers | Basic research |
The Virulence of S. marcescens Strains Isolated From Contaminated Blood Products Is Divergent in the C. elegans Infection Model | Diamandas A, Razon MR, Ramirez-Arcos S, Brassinga AKC | 2021 | Front Genet | View The Virulence of S. marcescens Strains Isolated From Contaminated Blood Products Is Divergent in the C. elegans Infection Model | Researchers | Basic research |
von Willebrand factor propeptide variants lead to impaired storage and ER retention in patient-derived endothelial colony-forming cells | Bowman M, Casey L, Selvam SN, Lima PDA, Rawley O, Hinds M, Tuttle A, Grabell J, Iorio A, Walker I, Lillicrap D, James P | 2022 | J Thromb Haemost | View von Willebrand factor propeptide variants lead to impaired storage and ER retention in patient-derived endothelial colony-forming cells | Researchers | Basic research |
Prevalence and significance of large granular lymphocytes in patients with immune thrombocytopenia | Gabe C, Liu Y, Duncan J, St John M, Lucier KJ, Kimmel D, Kelton JG, Arnold DM | 2023 | Platelets | View Prevalence and significance of large granular lymphocytes in patients with immune thrombocytopenia | Researchers | Clinical research |
ABO blood groups influence macrophage-mediated phagocytosis of Plasmodium falciparum-infected erythrocytes | Wolofsky KT, Ayi K, Branch DR, Hult AK, Olsson ML, Liles WC, Cserti-Gazdewich CM, Kain KC | 2012 | PLoS Pathog | View ABO blood groups influence macrophage-mediated phagocytosis of Plasmodium falciparum-infected erythrocytes | Researchers | Basic research |
Alteration of blood clotting and lung damage by protamine are avoided using the heparin and polyphosphate inhibitor UHRA | Kalathottukaren MT, Abraham L, Kapopara PR, Lai BFL, Shenoi RA, Rosell FI, Conway EM, Pryzdial ELG, Morrissey JH, Haynes CA, Kizhakkedathu JN | 2016 | Blood | View Alteration of blood clotting and lung damage by protamine are avoided using the heparin and polyphosphate inhibitor UHRA | Researchers | Basic research |
Can natural antibodies to VIP or VIP-like HIV-1 glycoprotein facilitate prevention and supportive treatment of breast cancer? | Veljkovic M, Branch DR, Dopsaj V, Veljkovic V, Veljkovic N, Glisic S, Colombatti A | 2011 | Med Hypotheses | View Can natural antibodies to VIP or VIP-like HIV-1 glycoprotein facilitate prevention and supportive treatment of breast cancer? | Researchers | Basic research |
Concentré de recherche: Mais où va le sang? Analysons la consommation des concentrés de globules rouges pour l'établissement des politiques | Zeller M, Heddle N, Devine D | 2017 | Blood.ca website | View Concentré de recherche: Mais où va le sang? Analysons la consommation des concentrés de globules rouges pour l'établissement des politiques | Researchers | Basic research |
Detection of bacterial adherence and biofilm formation on medical surfaces | Loza-Correa M, Ramirez-Arcos S | 2016 | Biofilms and implantable medical devices: infection and control | View Detection of bacterial adherence and biofilm formation on medical surfaces | Researchers | New or improved product or process |
Elevation of C-reactive protein levels in patients with transfusion-related acute lung injury | Kapur R, Kim M, Rondina MT, Porcelijn L, Semple JW | 2016 | Oncotarget | View Elevation of C-reactive protein levels in patients with transfusion-related acute lung injury | Researchers | Basic research |
Fetal and neonatal alloimmune thrombocytopenia: Novel mechanisms of miscarriage learned from placental pathology in animal models | Yougbare I, Zdravic D, Ni H | 2018 | J Pediatr Pediatr Med | View Fetal and neonatal alloimmune thrombocytopenia: Novel mechanisms of miscarriage learned from placental pathology in animal models | Researchers | Basic research |