Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Impact of osteoblast maturation on their paracrine growth enhancing activity on cord blood progenitors Alsheikh M, Abu?Khader A, Michalicka M, Pasha R, Pineault N 2017 Eur J Haematol View Researchers Basic research
How we treat paroxysmal nocturnal hemoglobinuria: A consensus statement of the Canadian PNH Network and review of the national registry Patriquin CJ, Kiss T, Caplan S, Chin-Yee I, Grewal K, Grossman J, Larratt L, Marceau D, Nevill T, Sutherland DR, Wells RA, Leber B 2019 Eur J Haematol View Researchers Clinical research
Gender and BCR-ABL transcript type are correlated with molecular response to imatinib treatment in patients with chronic myeloid leukemia Lin HX, Sjaarda J, Dyck J, Stringer R, Hillis C, Harvey M, Carter R, Ainsworth P, Leber B, Pare G, Sadikovic B 2016 Eur J Haematol View Researchers Clinical research
Switching to extended half-life products in Canada - preliminary data Keepanasseril A, Stoffman J, Bouskill V, Carcao M, Iorio A, Jackson S 2017 Haemophilia View Health care providers Clinical research
Test-retest properties of the Patient Reported Outcomes, Burdens and Experiences (PROBE) questionnaire and its constituent domains Chai-Adisaksopha C, Skinner MW, Curtis R, Frick N, Nichol MB, Noone D, O'Mahony B, Page D, Stonebraker J, Thabane L, Crowther MA, Iorio A 2019 Haemophilia View Researchers Clinical research
Treatment decision-making among Canadian youth with severe haemophilia: a qualitative approach Lane SJ, Walker I, Chan AK, Heddle NM, Poon MC, Minuk L, Jardine L, Arnold E, Sholapur N, Webert KE 2015 Haemophilia View Health care providers Clinical research
Converting factor and nonfactor usage into a single metric to facilitate benchmarking the resources consumed for haemophilia care across jurisdictions and over time Stonebraker JS, O'Mahony B, Noone D, Iorio A 2021 Haemophilia View Researchers Benchmarking and standard setting
Evaluation of the sexual health in people living with hemophilia Germini F, Chai-Adisaksopha C, Pete D, Curtis R, Frick N, Nichol MB, Noone D, O'Mahony B, Page D, Stonebraker JS, Thabane L, Crowther MA, Skinner MW, Iorio A 2021 Haemophilia View Researchers Clinical research
The importance of haemophilia treatment centre administrators in patient care Almonte T, Decker K, Seroski W, Walker I, Webert K, Bos C, Strike K, Waterhouse L, Goldsmith R, Chan AK 2012 Haemophilia View Health care providers Other
Challenges and key lessons from the design and implementation of an international haemophilia registry supported by a pharmaceutical company Hay CRM, Shima M, Makris M, Jiménez-Yuste V, Oldenburg J, Fischer K, Iorio A, Skinner MW, Santagostino E, von Mackensen S, Kessler CM 2020 Haemophilia View Researchers Clinical research
Rate and appropriateness of polypharmacy in older patients with hemophilia compared with age-matched controls Mannucci PM, Nobili A, Marchesini E, Oliovecchio E, Cortesi L, Coppola A, Santagostino E, Radossi P, Castaman G, Valdrè L, Santoro C, Tagliaferri A, Ettorre C, Zanon E, Barillari G, Cantori I, Caimi TM, Sottilotta G, Peyvandi F, Iorio A 2018 Haemophilia View Health care providers Clinical research
Exploring some intersections between pharmacokinetics, factor VIII measurement and human morphometrics - impact of recent advances in haemophilia study design on our understanding of optimal haemophilia treatment Iorio A, Edginton AN 2017 Haemophilia View Researchers Clinical research
Point of care ultrasound in haemophilia: Building a strong foundation for clinical implementation Lawson W, Uy M, Strike K, Iorio A, Stein N, Koziol L, Chan A 2017 Haemophilia View Health care providers Clinical research
Emicizumab state-of-the-art update Mahlangu J, Iorio A, Kenet G 2022 Haemophilia View Health care providers Clinical research
Switching from standard to extended half-life FVIII prophylaxis in haemophilia A: Comparison of factor product use, bleed rates and pharmacokinetics Nummi V, Lehtinen AE, Iorio A, Szanto T, Lassila R 2022 Haemophilia View Researchers Clinical research
Core outcome set for gene therapy in haemophilia: Results of the coreHEM multistakeholder project Iorio A, Skinner MW, Clearfield E, Messner D, Pierce GF, Witkop M, Tunis S 2018 Haemophilia View Health care providers Clinical research
Comparison of single subject and population-based pharmacokinetics for optimizing prophylaxis with simoctocog alfa in patients with haemophilia A Astermark J, Olsson A, Chelle P, Täckström K, Walger M, Magnusson M, Iorio A 2021 Haemophilia View Researchers Clinical research
Comorbidities in persons with haemophilia aged 60 years or more compared with age-matched people from the general population Marchesini E, Oliovecchio E, Coppola A, Santagostino E, Radossi P, Castaman G, Valdre L, Santoro C, Tagliaferri A, Ettorre C, Zanon E, Barillari G, Cantori I, Caimi TM, Sottilotta G, Iorio A, Mannucci PM 2018 Haemophilia View Health care providers Clinical research
A brief survey of clinicians' perceptions of parent preferences for involvement in obstetrical and perinatal management decisions in haemophilia Lucier KJ, Movilla RV, Parvizian MK, Siddiqui R, Gabriele EH, Bourque M, MacIsaac J, Moorehead PC, Chan AK, Heddle NM, Lane SJ 2018 Haemophilia View Health care providers Clinical research
Understanding stakeholder important outcomes and perceptions of equity, acceptability and feasibility of a care model for haemophilia management in the US: a qualitative study Lane SJ, Sholapur NS, Yeung CH, Iorio A, Heddle NM, Sholzberg M, Pai M 2016 Haemophilia View Health care providers Other
Target plasma factor levels for personalized treatment in haemophilia: a Delphi consensus statement Iorio A, Iserman E, Blanchette V, Dolan G, Escuriola Ettingshausen C, Hermans C, Negrier C, Oldenburg J, Reininger A, Rodriguez-Merchan C, Spannagl M, Valentino LA, Young G, Steinitz-Trost KN, Gringeri A 2017 Haemophilia View Health care providers Clinical research
A systematic review of definitions and reporting of bleeding outcome measures in haemophilia Chai-Adisaksopha C, Hillis C, Thabane L, Iorio A 2015 Haemophilia View Health care providers Clinical research
Patterns of joint damage in severe haemophilia A treated with prophylaxis Goren R, Pullenayegum E, Blanchette VS, Dover S, Carcao M, Israels SJ, Chan A, Rivard GE, Steele M, Cloutier S, Klaassen RJ, Sinha R, Price VE, Laferriere N, Paradis E, Wu JK, Feldman BM 2021 Haemophilia View Health care providers Clinical research
First analysis of 10-year trends in national factor concentrates usage in haemophilia: data from CHARMS, the Canadian Hemophilia Assessment and Resource Management System Traore AN, Chan AKC, Webert KE, Heddle N, Ritchie B, St-Louis J, Teitel J, Lillicrap D, Iorio A, Walker I 2014 Haemophilia View Health care providers Clinical research
Sexual issues in people with haemophilia: Awareness and strategies for overcoming communication barriers Blamey G, Van Tassel B, Sagermann E, Stain AM, Waterhouse L, Iorio A 2022 Haemophilia View Researchers Ethical, legal and social implications research
What should men living with haemophilia need to know? The perspectives of Canadian men with haemophilia Arnold E, Lane S, Webert KE, Chan A, Walker I, Tufts J, Rubin S, Poon MC, Heddle NM 2014 Haemophilia View Health care providers Other
Immunogenicity, efficacy and safety of Nuwiq® (human-cl rhFVIII) in previously untreated patients with severe haemophilia A-Interim results from the NuProtect Study Liesner RJ, Abashidze M, Aleinikova O, Altisent C, Belletrutti MJ, Borel-Derlon A, Carcao M, Chambost H, Chan AKC, Dubey L, Ducore J, Fouzia NA, Gattens M, Gruel Y, Guillet B, Kavardakova N, El Khorassani M, Klukowska A, Lambert T, Lohade S, Sigaud M, Turea V, Wu JKM, Vdovin V, Pavlova A, Jansen M, Belyanskaya L, Walter O, Knaub S, Neufeld EJ 2017 Haemophilia View Researchers Clinical research
Prophylaxis use of clotting factor replacement products in people with non-severe haemophilia: A review of the literature Iorio A, Königs C, Reding MT, Rotellini D, Skinner MW, Mancuso ME, Berntorp E 2023 Haemophilia View Health care providers Clinical research
What should men living with severe haemophilia need to know? The perspectives of Canadian haemophilia health care providers Lane S, Arnold E, Webert KE, Chan A, Walker I, Heddle NM 2013 Haemophilia View Health care providers Other
Past, present and future of haemophilia gene therapy: From vectors and transgenes to known and unknown outcomes Pierce GF, Iorio A 2018 Haemophilia View Health care providers New or improved product or process
Factor product utilization and health outcomes in patients with haemophilia A and B on extended half-life concentrates: A Canadian observational study of real-world outcomes Sun H, Yang M, Poon M-C, Lee A, Robinson KS, Sholzberg M, Wu J, Iorio A, Blanchette V, Carcao M, Klaassen RJ, Jackson S 2021 Haemophilia View Researchers Clinical research
A case of vertical transmission of Chagas Disease contracted via blood transfusion in Canada Fearon MA, Scalia V, Huang M, Dines I, Ndao M 2013 Can J Infect Dis Med Microbiol View Health care providers Clinical research
Buffy coat (top/bottom)- and whole-blood filtration (top/top)-produced red cell concentrates differ in size of extracellular vesicles Bicalho B, Pereira AS, Acker JP 2015 Vox Sang View Researchers Basic research
Efficiency of riboflavin and ultraviolet light treatment against high levels of biofilm?derived Staphylococcus epidermidis in buffy coat platelet concentrates Taha M, Culibrk B, Kalab M, Schubert P, Yi QL, Goodrich R, Ramirez?Arcos S 2017 Vox Sang View Researchers New or improved product or process
Registration errors among patients receiving blood transfusions: a national analysis from 2008 to 2017 Vijenthira S, Armali C, Downie H, Wilson A, Paton K, Berry B, Wu HX, Robitaille A, Cserti-Gazdewich C, Callum J 2021 Vox Sang View Health care providers Clinical research
PEGylation prevents bacteria-induced platelet activation and biofilm formation in platelet concentrates Greco CA, Maurer-Spurej E, Scott MD, Kalab M, Nakane N, Rami­rez-Arcos SM 2011 Vox Sang View Researchers Basic research
Biofilm-associated accumulation-associated protein (Aap): A contributing factor to the predominant growth of Staphylococcus epidermidis in platelet concentrates Alabdullatif M, Ramirez-Arcos S 2019 Vox Sang View Researchers New or improved product or process
A cross-sectional study of haemolytic disease of the newborn in Uganda Dhabangi A, Nankunda J, Okaba V, Nakubulwa S, Hume HA, Dzik WH, Heddle NM 2022 Vox Sang View Health care providers Clinical research
Establishment of the first International Repository for Transfusion-Relevant Bacteria Reference Strains: ISBT Working Party Transfusion-Transmitted Infectious Diseases (WP-TTID), Subgroup on Bacteria Stormer M, Arroyo A, Brachert J, Carrero H, Devine D, Epstein JS, Gabriel C, Gelber C, Goodrich R, Hanschmann KM, Heath DG, Jacobs MR, Keil S, de Korte D, Lambrecht B, Lee CK, Marcelis J, Marschner S, McDonald C, McGuane S, McKee M, Muller TH, Muthivhi T, Pettersson A, Radziwon P, Ramirez-Arcos S, Reesink HW, Rojo J, Rood I, Schmidt M, Schneider CK, Seifried E, Sicker U, Wendel S, Wood EM, Yomtovian RA, Montag T 2012 Vox Sang View Blood operators Benchmarking and standard setting
Vox Sanguinis International Forum on donor notification and counselling strategies for markers of transfusion?transmissible infections: Summary Sharma R, Lozano M, Fearon M, Bigham M, Djoudi R, Gallian P, Woimant G, Lee C, Leung J, Tsoi W 2017 Vox Sang View Blood operators New or improved product or process
Vox Sanguinis International Forum on Donor Incentives: Summary Zeller MP, Ellingham D, Devine D, Lozano M, Lewis P, Zhiburt E, van der Linde L, Goldman M, Nakamura A, Inoue S, Takikawa M, Nakajima K, Turek P, Rehacek V, Sakashita AM, Kutner JM, Karim FA, Hindawi S, Jayasekara SBA, Merz EM, Gross S, Woimant G, Djoudi R, Byabazaire KD, Irving DO, Abdrakhmanova S, Khalykova A, Yilmaz S, Oruc NE, Huaynalaya IP, Ramirez LAS, Chuhriiev A 2020 Vox Sang View Blood operators Benchmarking and standard setting
Quality control of apheresis platelets: a multicentre study to evaluate factors that can influence pH measurement Germain M, Grégoire Y, Vassallo RR, Acker JP, Cardigan R, de Korte D, Irving DO, Bégué S, on behalf of the BEST Collaborative 2017 Vox Sang View Researchers New or improved product or process
HIV residual risk in Canada under a three-month deferral for men who have sex with men O'Brien SF, Gregoire Y, Pillonel J, Steele WR, Custer B, Davison KL, Germain M, Lewin A, Seed CR 2020 Vox Sang View Researchers Other
White paper on pandemic preparedness in the blood supply Strengers P, O'Brien SF, Politis C, Mayr W, Seifried E, Spencer BR 2023 Vox Sang View Blood operators Benchmarking and standard setting
Risk-based decision making in transfusion medicine Leach Bennett J, Devine DV 2018 Vox Sang View Researchers New or improved product or process
Human T-cell lymphotropic virus: A simulation model to estimate residual risk with universal leucoreduction and testing strategies in Canada O'Brien SF, Yi Q-L, Goldman M, Grégoire Y, Delage G 2018 Vox Sang View Researchers New or improved product or process
Whole blood donor return rates after deferral for tattooing or body piercing—Survey across blood donation services: The BEST collaborative study Quee F, O'Brien SF, Prinsze F, Steele WR, Grégoire Y, Cutajar A, Wendel S, Compernolle V, Goldman M, van den Hurk K, Biomedical Excellence for Safer Transfusion Collaborative 2022 Vox Sang View Blood operators Benchmarking and standard setting
Lipoprotein enrichment in orange insoluble particulate matter reproducibly appearing in cryoprecipitate Sheffield WP, Bhakta V, Trigatti B, Jenkins C 2011 Vox Sang View Blood operators Basic research
The effect of processing method on the in vitro characteristics of red blood cell products Hansen AL, Kurach JDR, Turner TR, Jenkins C, Busch MP, Norris PJ, Dugger J, Tomasulo PA, Devine DV, Acker JP 2015 Vox Sang View Researchers Basic research
Vox Sanguinis International Forum on platelet cryopreservation Cohn CS, Dumont LJ, Lozano M, Marks DC, Johnson L, Ismay S, Bondar N, T'Sas F, Yokoyama APH, Kutner JM, Acker JP, Bohonek M, Sailliol A, Martinaud C, Poglod R, Antoniewicz-Papis J, Lachert E, Pun PBL, Lu J, Cid J, Guijarro F, Puig L, Gerber B, Alberio L, Schanz U, Buser A, Noorman F, Zoodsma M, van der Meer PF, de Korte D, Wagner S, O'Neill M 2017 Vox Sang View Blood operators New or improved product or process