Our Research Publications
Updated November 2023
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Title | Authors | Year | Journal | Link to Article | Intended Audience Sort descending | Purpose |
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Distribution, origin and contamination risk of coagulase-negative staphylococci from platelet concentrates | Rood IGH, de Korte D, RamÃrez-Arcos S, Savelkoul PHM, Pettersson A | 2011 | J Med Microbiol | View Distribution, origin and contamination risk of coagulase-negative staphylococci from platelet concentrates | Researchers | Basic research |
Effectiveness and safety of thiotepa as conditioning treatment prior to stem cell transplant in patients with central nervous system lymphoma | Kokolo MB, Fergusson D, O'Neill J, Tay J, Tinmouth AT, Stewart D, Bredeson C | 2014 | Leuk Lymphoma | View Effectiveness and safety of thiotepa as conditioning treatment prior to stem cell transplant in patients with central nervous system lymphoma | Researchers | Clinical research |
Evaluating mesenchymal stem cell therapy for sepsis with preclinical meta-analyses prior to initiating a first-in-human trial | Lalu MM, Sullivan KJ, Mei SHJ, Moher D, Straus A, Fergusson DA, Stewart DJ, Jazi M, MacLeod M, Winston B, Marshall J, Hutton B, Walley KR, McIntyre L | 2016 | eLife | View Evaluating mesenchymal stem cell therapy for sepsis with preclinical meta-analyses prior to initiating a first-in-human trial | Researchers | Clinical research |
Intravenous immunoglobulin treatment of spleen cells from patients with immune thrombocytopenia significantly increases the percentage of myeloid-derived suppressor cells | Aslam R, Burack WR, Segel GB, McVey M, Spence SA, Semple JW | 2017 | Br J Haematol | View Intravenous immunoglobulin treatment of spleen cells from patients with immune thrombocytopenia significantly increases the percentage of myeloid-derived suppressor cells | Researchers | Basic research |
Microfluidic cell-phoresis enabling high-throughput analysis of red blood cell deformability and biophysical screening of antimalarial drugs | Santoso AT, Deng X, Lee J-H, Matthews K, Duffy SP, Islamzada E, McFaul SM, Myrand-Lapierre M-E, Ma H | 2015 | Lab Chip | View Microfluidic cell-phoresis enabling high-throughput analysis of red blood cell deformability and biophysical screening of antimalarial drugs | Researchers | New or improved product or process |
Multiplexed fluidic plunger mechanism for the measurement of red blood cell deformability | Myrand-Lapierre ME, Deng X, Ang RR, Matthews K, Santoso AT, Ma H | 2015 | Lab Chip | View Multiplexed fluidic plunger mechanism for the measurement of red blood cell deformability | Researchers | New or improved product or process |
Plant-based food cyanidin-3-glucoside modulates human platelet glycoprotein vi signaling and inhibits platelet activation and thrombus formation | Yao Y, Chen Y, Adili R, McKeown T, Chen P, Zhu G, Li D, Ling W, Ni H, Yang Y | 2017 | J Nutr | View Plant-based food cyanidin-3-glucoside modulates human platelet glycoprotein vi signaling and inhibits platelet activation and thrombus formation | Researchers | Basic research |
Polymer Brushes | Hadjesfandiari N, Bajgai MP, Yu K, Brooks DE, Kizhakkedathu JN | 2013 | Encyclopedia of Polymer Science and Technology | View Polymer Brushes | Researchers | Basic research |
Proteomic analysis of red blood cells from donors exhibiting high hemolysis demonstrates a reduction in membrane?associated proteins involved in the oxidative response | Chen D, Schubert P, Devine DV | 2017 | Transfusion | View Proteomic analysis of red blood cells from donors exhibiting high hemolysis demonstrates a reduction in membrane?associated proteins involved in the oxidative response | Researchers | Basic research |
Red cell transfusion-associated hemolysis in cardiac surgery: an observational cohort study | Karkouti K, Callum J, Acker JP, Yip P, Rao V | 2017 | Anesth Analg | View Red cell transfusion-associated hemolysis in cardiac surgery: an observational cohort study | Researchers | Clinical research |
Reversible hemostatic properties of sulfabetaine/quaternary ammonium modified hyperbranched polyglycerol | Wen J, Weinhart M, Lai B, Kizhakkedathu J, Brooks DE | 2016 | Biomaterials | View Reversible hemostatic properties of sulfabetaine/quaternary ammonium modified hyperbranched polyglycerol | Researchers | Basic research |
The effect of timing of gamma-irradiation on hemolysis and potassium release in leukoreduced red cell concentrates stored in SAGM | Serrano K, Chen D, Hansen AL, Levin E, Turner TR, Kurach JDR, Acker JP, Devine DV | 2014 | Vox Sang | View The effect of timing of gamma-irradiation on hemolysis and potassium release in leukoreduced red cell concentrates stored in SAGM | Researchers | New or improved product or process |
Thymic retention of CD4+CD25+FoxP3+ T regulatory cells is associated with their peripheral deficiency and thrombocytopenia in a murine model of immune thrombocytopenia | Aslam R, Hu Y, Gebremeskel S, Segel GB, Speck ER, Guo L, Kim M, Ni H, Freedman J, Semple JW | 2012 | Blood | View Thymic retention of CD4+CD25+FoxP3+ T regulatory cells is associated with their peripheral deficiency and thrombocytopenia in a murine model of immune thrombocytopenia | Researchers | Basic research |
Two-stage, in silico deconvolution of the lymphocyte compartment of the peripheral whole blood transcriptome in the context of acute kidney allograft rejection | Shannon CP, Balshaw R, Ng RT, Wilson-McManus JE, Keown P, McMaster R, McManus BM, Landsberg D, Isbel NM, Knoll G, Tebbutt SJ | 2014 | PLoS One | View Two-stage, in silico deconvolution of the lymphocyte compartment of the peripheral whole blood transcriptome in the context of acute kidney allograft rejection | Researchers | Basic research |
Improving Time to Antibiotics for Pediatric Oncology Patients With Fever and Suspected Neutropenia by Applying Lean Principles | Geerlinks AV, Digout C, Bernstein M, Chan A, MacPhee S, Pambrun C, Gallant G, Wyatt L, Fernandez CV, Price VE | 2018 | Pediatric Emergency Care | View Improving Time to Antibiotics for Pediatric Oncology Patients With Fever and Suspected Neutropenia by Applying Lean Principles | Researchers | New or improved product or process |
The effect of tantalum incorporation on the physical and chemical properties of ternary silicon–calcium–phosphorous mesoporous bioactive glasses | Mendonca A, Rahman MS, Alhalawani A, Rodriguez O, Gallant RC, Ni H, Clarkin OM, Towler MR | 2019 | J Biomed Mater Res B Appl Biomater | View The effect of tantalum incorporation on the physical and chemical properties of ternary silicon–calcium–phosphorous mesoporous bioactive glasses | Researchers | Basic research |
Trends and outcomes in multicomponent blood transfusion: an 11-year cohort study of a large multisite academic center | Perelman I, Saidenberg E, Tinmouth A, Fergusson D | 2019 | Transfusion | View Trends and outcomes in multicomponent blood transfusion: an 11-year cohort study of a large multisite academic center | Researchers | Clinical research |
rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and Fc?Rs | Spirig R, Campbell IK, Koernig S, Chen C-G, Lewis BJB, Butcher R, Muir I, Taylor S, Chia J, Leong D, Simmonds J, Scotney P, Schmidt P, Fabri L, Hofmann A, Jordi M, Spycher MO, Cattepoel S, Brasseit J, Panousis C, Rowe T, Branch DR, Baz Morelli A, Kaesermann F, Zuercher AW | 2018 | J Immunol | View rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and Fc?Rs | Researchers | Basic research |
Acquired factor XIII deficiency: A review | Yan MTS, Rydz N, Goodyear D, Sholzberg M | 2018 | Transfus Apher Sci | View Acquired factor XIII deficiency: A review | Researchers | Other |
Comparative pharmacokinetics of two extended half-life FVIII concentrates (Eloctate and Adynovate) in adolescents with hemophilia A: Is there a difference? | Carcao MD, Chelle P, Clarke E, Kim L, Tiseo L, Morfini M, Hossain T, Rand ML, Brown C, Edginton AN, Lillicrap D, Iorio A, Blanchette VS | 2019 | J Thromb Haemost | View Comparative pharmacokinetics of two extended half-life FVIII concentrates (Eloctate and Adynovate) in adolescents with hemophilia A: Is there a difference? | Researchers | Clinical research |
Barriers and enablers to source plasma donation by gay, bisexual and other men who have sex with men under revised eligibility criteria: protocol for a multiple stakeholder feasibility study | Vesnaver E, Goldman M, O’Brien S, MacPherson P, Butler-Foster T, Lapierre D, Otis J, Devine DV, Germain M, Rosser A, MacDonagh R, Randall T, Osbourne-Sorrell W, Clement-Thorne B, Al-Bakri TB, Rubini KA, Hill NE, Presseau J | 2020 | Health Res Policy Syst | View Barriers and enablers to source plasma donation by gay, bisexual and other men who have sex with men under revised eligibility criteria: protocol for a multiple stakeholder feasibility study | Researchers | MSM research |
The Missing Pieces to the Cold-Stored Platelet Puzzle | Zhao H, Devine DV | 2022 | Int J Mol Sci | View The Missing Pieces to the Cold-Stored Platelet Puzzle | Researchers | Basic research |
Use of CRISPR/Cas9 gene editing to improve chimeric antigen-receptor T cell therapy: A systematic review and meta-analysis of preclinical studies | Maganti HB, Kirkham AM, Bailey AJM, Shorr R, Kekre N, Pineault N, Allan DS | 2022 | Cytotherapy | View Use of CRISPR/Cas9 gene editing to improve chimeric antigen-receptor T cell therapy: A systematic review and meta-analysis of preclinical studies | Researchers | Clinical research |
The international experience of bacterial screen testing of platelet components with automated microbial detection systems: An update | Kamel H, Ramirez-Arcos S, McDonald C, ISBT Transfusion-Transmitted Infectious Disease Bacterial Working Party Bacterial Subgroup | 2022 | Vox Sang | View The international experience of bacterial screen testing of platelet components with automated microbial detection systems: An update | Researchers | Benchmarking and standard setting |
Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis | Almizraq RJ, Frias Boligan K, Lewis BJB, Cen S, Whetstone H, Spirig R, Käsermann F, Campbell IK, von Gunten S, Branch DR | 2023 | Pharmacology | View Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis | Researchers | Basic research |
THP-1 cells transduced with CD16A utilize Fcγ receptor I and III in the phagocytosis of IgG-sensitized human erythrocytes and platelets | Gil Gonzalez L, Fernandez-Marrero Y, Norris PAA, Tawhidi Z, Shan Y, Cruz-Leal Y, Won KD, Frias-Boligan K, Branch DR, Lazarus AH | 2022 | PLoS One | View THP-1 cells transduced with CD16A utilize Fcγ receptor I and III in the phagocytosis of IgG-sensitized human erythrocytes and platelets | Researchers | Basic research |
ABO O blood group as a risk factor for platelet reactivity in heparin-induced thrombocytopenia | Karnes JH, Rollin J, Giles JB, Martinez KL, Steiner HE, Shaffer CM, Momozawa Y, Inai C, Bombin A, Shi M, Mosley JD, Stanaway I, Selleng K, Thiele T, Mushiroda T, Pouplard C, Heddle NM, Kubo M, Phillips EJ, Warkentin TE, Gruel Y, Greinacher A, Roden DM | 2022 | Blood | View ABO O blood group as a risk factor for platelet reactivity in heparin-induced thrombocytopenia | Researchers | Basic research |
Small Molecule Drugs That Inhibit Phagocytosis | Loriamini M, Lewis-Bakker MM, Frias Boligan K, Wang S, Holton MB, Kotra LP, Branch DR | 2023 | Molecules | View Small Molecule Drugs That Inhibit Phagocytosis | Researchers | Basic research |
Multicenter evaluation of the IL-3-pSTAT5 assay to assess the potency of cryopreserved stem cells from cord blood units: The BEST Collaborative study | Trépanier P, Fournier D, Simard C, Fontaine MJ, Stroncek D, Takanashi M, McKenna D, Schwartz J, Tanhehco YC, Reems J-A, Torrents S, Kogler G, Liedtke S, Giroux M, Holovati JL, Louis I, Prasath A, Pineault N, Bazin R, The Biomedical Excellence for Safer Transfusion Collaborative | 2022 | Transfusion | View Multicenter evaluation of the IL-3-pSTAT5 assay to assess the potency of cryopreserved stem cells from cord blood units: The BEST Collaborative study | Researchers | Benchmarking and standard setting |
A lab-on-chip for malaria diagnosis and surveillance | Taylor BJ, Howell A, Martin KA, Manage DP, Gordy W, Campbell SD, Lam S, Jin A, Polley SD, Samuel RA, Atrazhev A, Stickel AJ, Birungi J, Mbonye AK, Pilarski LM, Acker JP, Yanow SK | 2014 | Malar J | View A lab-on-chip for malaria diagnosis and surveillance | Researchers | Basic research |
Applications of Liposomes in Biopreservation | Da Silveira Cavalcante L, Holovati J, Acker J | 2016 | Multiscale technologies for cryomedicine: implementation from nano to macroscale | View Applications of Liposomes in Biopreservation | Researchers | Basic research |
Biomonitoring of Arsenic in Urine and Saliva of Children Playing on Playgrounds Constructed from Chromated Copper Arsenate-Treated Wood | Lew K, Acker JP, Gabos S, Le XC | 2010 | Environ Sci Technol | View Biomonitoring of Arsenic in Urine and Saliva of Children Playing on Playgrounds Constructed from Chromated Copper Arsenate-Treated Wood | Researchers | Other |
Carbohydrate-based ice recrystallization inhibitors increase infectivity and thermostability of viral vectors | Ghobadloo SM, Balcerzak AK, Gargaun A, Muharemagic D, Mironov GG, Capicciotti CJ, Briard JG, Ben RN, Berezovski MV | 2014 | Sci Rep | View Carbohydrate-based ice recrystallization inhibitors increase infectivity and thermostability of viral vectors | Researchers | Basic research |
Emerging Role for Use of Liposomes in the Biopreservation of Red Blood Cells | Holovati JL, Acker JP | 2011 | Transfus Med Hemother | View Emerging Role for Use of Liposomes in the Biopreservation of Red Blood Cells | Researchers | Basic research |
Fibronectin: extra domain brings extra risk? | Wang Y, Ni H | 2015 | Blood | View Fibronectin: extra domain brings extra risk? | Researchers | Other |
Immunocamouflage of latex surfaces by grafted methoxypoly(ethylene glycol) (mPEG): proteomic analysis of plasma protein adsorption | Le Y, Li L, Wang D, Scott MD | 2012 | Sci China Life Sci | View Immunocamouflage of latex surfaces by grafted methoxypoly(ethylene glycol) (mPEG): proteomic analysis of plasma protein adsorption | Researchers | Basic research |
Incorporation of albumin fusion proteins into fibrin clots in vitro and in vivo: comparison of different fusion motifs recognized by factor XIIIa | Sheffield WP, Eltringham-Smith LJ | 2011 | BMC Biotechnol | View Incorporation of albumin fusion proteins into fibrin clots in vitro and in vivo: comparison of different fusion motifs recognized by factor XIIIa | Researchers | Basic research |
Manufacturing method affects mitochondrial DNA release and extracellular vesicle composition in stored red blood cells | Bakkour S, Acker JP, Chafets DM, Inglis HC, Norris PJ, Lee TH, Busch MP | 2016 | Vox Sang | View Manufacturing method affects mitochondrial DNA release and extracellular vesicle composition in stored red blood cells | Researchers | Basic research |
Mitochondria and membrane cryoinjury in micropatterned cells: Effects of cell-cell interactions | Tchir J, Acker JP | 2010 | Cryobiology | View Mitochondria and membrane cryoinjury in micropatterned cells: Effects of cell-cell interactions | Researchers | Basic research |
Platelet immunology in China: research and clinical applications | Wu G, Zhou Y, Li L, Zhong Z, Li H, Li H, Yu M, Shen W, Ni H | 2017 | Transfus Med Rev | View Platelet immunology in China: research and clinical applications | Researchers | Clinical research |
Renin-Angiotensin System Blockade and Long-term Clinical Outcomes in Kidney Transplant Recipients: A Meta-analysis of Randomized Controlled Trials | Hiremath S, Fergusson DA, Fergusson N, Bennett A, Knoll GA | 2017 | Am J Kidney Dis | View Renin-Angiotensin System Blockade and Long-term Clinical Outcomes in Kidney Transplant Recipients: A Meta-analysis of Randomized Controlled Trials | Researchers | Clinical research |
Solving the dilemma of prevention of red cell alloimmunization | Branch DR | 2012 | Immunotherapy | View Solving the dilemma of prevention of red cell alloimmunization | Researchers | Other |
The Fanconi anemia pathway has a dual function in Dickkopf-1 transcriptional repression | Huard CC, Tremblay CS, Magron A, Levesque G, Carreau M | 2014 | PNAS | View The Fanconi anemia pathway has a dual function in Dickkopf-1 transcriptional repression | Researchers | Basic research |
The role of inflammation in intravenous immune globulin-mediated hemolysis | Pendergrast J, Willie-Ramharack K, Sampson L, Laroche V, Branch DR | 2015 | Transfusion | View The role of inflammation in intravenous immune globulin-mediated hemolysis | Researchers | Clinical research |
Transfusion of fresher vs older red blood cells in hospitalized patients: a systematic review and meta-analysis | Alexander PE, Barty R, Fei Y, Vandvik PO, Pai M, Siemieniuk RA, Heddle NM, Blumberg N, McLeod SL, Liu J, Eikelboom JW, Guyatt GH | 2016 | Blood | View Transfusion of fresher vs older red blood cells in hospitalized patients: a systematic review and meta-analysis | Researchers | Clinical research |
ResearchUnit: A different way to look at red blood cell quality | Acker J | 2018 | Blood.ca website | View ResearchUnit: A different way to look at red blood cell quality | Researchers | Clinical research |
Characterization of platelet factor 4 amino acids that bind pathogenic antibodies in heparin-induced thrombocytopenia | Huynh A, Arnold DM, Kelton JG, Smith JW, Horsewood P, Clare R, Guarné A, Nazy I | 2018 | J Thromb Haemost | View Characterization of platelet factor 4 amino acids that bind pathogenic antibodies in heparin-induced thrombocytopenia | Researchers | Basic research |
IVIg and LPS Co-stimulation Induces IL-10 Production by Human Monocytes, Which Is Compromised by an FcgRIIA Disease-Associated Gene Variant | Kozicky LK, Menzies SC, Zhao ZY, Vira T, Harnden K, Safari K, Del Bel KL, Turvey SE, Sly LM | 2018 | Front Immunol | View IVIg and LPS Co-stimulation Induces IL-10 Production by Human Monocytes, Which Is Compromised by an FcgRIIA Disease-Associated Gene Variant | Researchers | Basic research |
What's in a name? Patient registration errors and their threat to transfusion safety | Ning S, Yan MTS, Downie H, Callum J | 2018 | Transfusion | View What's in a name? Patient registration errors and their threat to transfusion safety | Researchers | New or improved product or process |
Raman spectroscopy of stored red blood cell concentrate within sealed transfusion blood bags | Vardaki MZ, Atkins CG, Schulze HG, Devine DV, Serrano K, Blades MW, Turner RFB | 2018 | Analyst | View Raman spectroscopy of stored red blood cell concentrate within sealed transfusion blood bags | Researchers | New or improved product or process |