Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Vaccine-induced immune thrombotic thrombocytopenia Klok FA, Pai M, Huisman MV, Makris M 2022 Lancet Haematol View Researchers Clinical research
International Forum on the Collection and Use of COVID-19 Convalescent Plasma: Responses Al-Riyami AZ, Burnouf T, Yazer M, Triulzi D, Kuma? LT, Sa?dur L, Pelit NB, Bazin R, Hindawi SI, Badawi MA, Patidar GK, Pandey HC, Chaurasia R, Fachini RM, Scuracchio P, Wendel S, Ang AL, Ong KH, Young P, Ihalainen J, Vierikko A, Qiu Y, Yang R, Xu H, Rahimi-Levene N, Shinar E, Izak M, Gonzalez CA, Ferrari DM, Cini PV, Aditya RN, Sharma RR, Sachdev S, Hans R, Lamba DS, Nissen-Meyer LSH, Devine DV, Lee CK, Leung JN-S, Hung IFN, Tiberghien P, Gallian P, Morel P, Al Maamari K, Al-Hinai Z, Vrielink H, So-Osman C, De Angelis V, Berti P, Ostuni A, Marano G, Nevessignsky MT, El Ekiaby M, Daly J, Hoad V, Kim S, van den Berg K, Vermeulen M, Glatt TN, Schäfer R, Reik R, Gammon R, Lopez M, Estcourt L, MacLennan S, Roberts D, Louw V, Dunbar N 2021 Vox Sang View Researchers Clinical research
Structurally Modified Bioactive Peptide Inhibits SARS-CoV-2 Lentiviral Particles Expression Bhullar KS, Nael MA, Elokely KM, Drews SJ, Wu J 2022 Pharmaceutics View Researchers Basic research
Venous thromboembolism in pediatric inflammatory bowel disease: an 11-year population-based nested case-control study in Canada Ding Z, Sherlock M, Chan AKC, Zachos M 2022 Blood Coagul Fibrinolysis View Researchers Clinical research
Assessing unintentional creation of bias against men who have sex with men as a function of exposure to blood donor screening questionnaire: A national randomized controlled trial Hofkirchner A, Kohut T, O'Brien SF, Fisher WA 2022 Transfusion View Researchers MSM research
A novel compensating mechanism for homozygous coagulation factor V deficiency suggested by enhanced activated partial thromboplastin time after reconstitution with normal factor V Talbot K, Song J, Hewitt J, Serrano K, Ho M, Carter CJ, MacGillivray RTA, Pryzdial ELG 2010 Br J Haematol View Researchers Basic research
CD8(+) T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia Qiu J, Liu X, Li X, Zhang X, Han P, Zhou H, Shao L, Hou Y, Min Y, Kong Z, Wang Y, Wei Y, Liu X, Ni H, Peng J, Hou M 2016 Sci Rep View Researchers Basic research
Coagulation factor X Arg386 specifically affects activation by the intrinsic pathway: a novel patient mutation Vanden Hoek AL, Talbot K, Carter IS, Vickars L, Carter CJ, Jackson SC, Macgillivray RT, Pryzdial EL 2012 J Thromb Haemost View Researchers Basic research
c-Src and Pyk2 protein tyrosine kinases play protective roles in early HIV-1 infection of CD4+ T cell lines McCarthy SDS, Jung D, Sakac D, Branch DR 2014 J Acquir Immune Defic Syndr View Researchers Basic research
Drugs in ITP: Mechanisms of Action Crow AR, Lazarus AH 2013 Immune Thrombocytopenia (ITP) View Researchers Other
Enhancing blood donor skin disinfection using natural oils Alabdullatif M, Boujezza I, Mekni M, Taha M, Kumaran D, Yi QL, Landoulsi A, Ramirez-Arcos S 2017 Transfusion View Researchers New or improved product or process
Exploring some intersections between pharmacokinetics, factor VIII measurement and human morphometrics - impact of recent advances in haemophilia study design on our understanding of optimal haemophilia treatment Iorio A, Edginton AN 2017 Haemophilia View Researchers Clinical research
Hyaluronic acid and thrombin upregulate MT1-MMP through PI3K and Rac-1 signaling and prime the homing-related responses of cord blood hematopoietic stem/progenitor cells Shirvaikar N, Marquez-Curtis LA, Ratajczak MZ, Janowska-Wieczorek A 2011 Stem Cells Dev View Researchers Basic research
Liposomes alter thermal phase behavior and composition of red blood cell membranes Stoll C, Stadnick H, Kollas O, Holovati JL, Glasmacher B, Acker JP, Wolkers WF 2011 Biochim Biophys Acta View Researchers Basic research
Microfluidic analysis of red blood cell deformability as a means to assess hemin-induced oxidative stress resulting from Plasmodium falciparum intraerythrocytic parasitism Matthews K, Duffy SP, Myrand-Lapierre M-E, Ang RR, Li L, Scott MD, Ma H 2017 Integr Biol View Researchers Basic research
MT1-MMP association with membrane lipid rafts facilitates G-CSF?induced hematopoietic stem/progenitor cell mobilization Shirvaikar N, Marquez-Curtis LA, Shaw AR, Turner AR, Janowska-Wieczorek A 2010 Exp Hematol View Researchers Basic research
Plant food anthocyanins inhibit platelet granule secretion in hypercholesterolaemia: Involving the signalling pathway of PI3K–Akt Song F, Zhu Y, Shi Z, Tian J, Deng X, Ren J, Andrews MC, Ni H, Ling W, Yang Y 2014 Thromb Haemost View Researchers Basic research
Proteolytic modulation of factor Xa-antithrombin complex enhances fibrinolysis in plasma Talbot K, Meixner SC, Pryzdial EL 2013 Biochim Biophys Acta View Researchers Basic research
Red blood cell transfusion and mortality effect in aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis protocol English SW, Chassé M, Turgeon AF, Tinmouth A, Boutin A, Pagliarello G, Fergusson D, McIntyre L 2015 Syst Rev View Researchers Clinical research
Retention of thrombin inhibitory activity by recombinant serpins expressed as integral membrane proteins tethered to the surface of mammalian cells Gierczak RF, Sutherland JS, Bhakta V, Toltl LJ, Liaw PC, Sheffield WP 2011 J Thromb Haemost View Researchers Basic research
The platelet "sugar high" in diabetes Ni H 2012 Blood View Researchers Other
Thrombolysis by chemically modified coagulation factor Xa Pryzdial ELG, Meixner SC, Talbot K, Eltringham-Smith LJ, Baylis JR, Lee FMH, Kastrup CJ, Sheffield WP 2016 J Thromb Haemost View Researchers Basic research
Serologic problems associated with administration of intravenous immune globulin (IVIg) Branch DR 2019 Immunohematology View Researchers Clinical research
A Retrospective Chart Review of Transfusion Practices in the Palliative Care Unit Setting Sirianni G, Perri G, Callum J, Gardner S, Berall A, Selby D 2018 Am J Hosp Palliat Care View Researchers Clinical research
Whole blood donors with antibodies Yan M 2019 Blood.ca website View Researchers Basic research
Coenzyme Q10 Upregulates Platelet cAMP/PKA Pathway and Attenuates Integrin alpha II beta 3 Signaling and Thrombus Growth Ya F, Xu XR, Shi Y, Gallant RC, Song F, Zuo X, Zhao Y, Tian Z, Zhang C, Xu X, Ling W, Ni H, Yang Y 2019 Mol Nutr Food Res View Researchers Basic research
Feasibility of photoacoustic imaging for the non-invasive quality management of stored blood bags Pinto RN, Hysi E, Bagga K, Sebastian JA, Douplik A, Acker JP, Kolios MC 2019 Vox Sang View Researchers New or improved product or process
Proposal of a two-step process for the diagnosis of sepsis-induced disseminated intravascular coagulation Iba T, Levy JH, Yamakawa K, Thachil J, Warkentin TE, Levi M, Scientific and Standardization Committee on DIC of the International Society on Thrombosis and Haemostasis 2019 J Thromb Haemost View Researchers New or improved product or process
Targeting ABL1 or ARG Tyrosine Kinases to Restrict HIV-1 Infection in Primary CD4+ T?Cells or in Humanized NSG Mice McCarthy SDS, Leontyev D, Nicoletti P, Binnington B, Kozlowski HN, Ostrowski M, Cochrane A, Branch DR, Wong RW 2019 J Acquir Immune Defic Syndr View Researchers Basic research
Clinically approved IVIg delivered to the hippocampus with focused ultrasound promotes neurogenesis in a model of Alzheimer’s disease Dubey S, Heinen S, Krantic S, McLaurin J, Branch DR, Hynynen K, Aubert I 2020 PLoS Pathog View Researchers Basic research
Proliferative and Regenerative Effect of Acetonic Extract of Feijoa sellowiana on Stem Cells Rasekh H, Hoseini Farahi M, Mehrabani D, Massoumi SJ, Ramzi M, Acker JP 2020 World J Plast Surg View Researchers Basic research
Stepwise Reversion of Multiply Mutated Recombinant Antitrypsin Reveals a Selective Inhibitor of Coagulation Factor XIa as Active as the M358R Variant Hamada M, Bhakta V, Andres SN, Sheffield WP 2021 Front Cardiovasc Med View Researchers Basic research
Estimating SARS-CoV-2 Seroprevalence in Canadian Blood Donors, April 2020 to March 2021: Improving Accuracy with Multiple Assays Tuite AR, Fisman D, Abe KT, Rathod B, Pasculescu A, Colwill K, Gingras A-C, Yi Q-L, O’Brien SF, Drews SJ, Pride DT 2022 Microbiol Spectr View Researchers Basic research
Current challenges of severe acute respiratory syndrome coronavirus 2 seroprevalence studies among blood donors: A scoping review Saeed S, Uzicanin S, Lewin A, Lieshout-Krikke R, Faddy H, Erikstrup C, Osiowy C, Seed CR, Steele WR, Davison K, Custer B, O'Brien SF, Assessment SR, Policy Sub-group of the Transfusion Transmitted Infectious Diseases Working Party of the International Society of Blood Transfusion 2022 Vox Sang View Researchers Basic research
Novel Mechanisms of Thrombopoietin Generation: The Essential Role of Kupffer Cells Karakas D, Li J, Ni H 2021 Blood View Researchers Basic research
Anti-platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein Greinacher A, Selleng K, Mayerle J, Palankar R, Wesche J, Reiche S, Aebischer A, Warkentin TE, Muenchhoff M, Hellmuth JC, Keppler OT, Duerschmied D, Lother A, Rieg S, Gawaz MP, Mueller KAL, Scheer CS, Napp M, Hahnenkamp K, Lucchese G, Vogelgesang A, Flöel A, Lovreglio P, Stufano A, Marschalek R, Thiele T 2021 Blood View Researchers Clinical research
Risk factors for neonatal thrombosis: A retrospective study conducted in a single Canadian intensive care unit Bhatia K, Solanki S, Paes B, Chan AKC, Bhatt MD 2022 Pediatr Blood Cancer View Researchers Clinical research
Mitapivat versus Placebo for Pyruvate Kinase Deficiency Al-Samkari H, Galactéros F, Glenthøj A, Rothman JA, Andres O, Grace RF, Morado-Arias M, Layton DM, Onodera K, Verhovsek M, Barcellini W, Chonat S, Judge MP, Zagadailov E, Xu R, Hawkins P, Beynon V, Gheuens S, van Beers EJ 2022 N Engl J Med View Researchers Clinical research
Chemokines IP-10/CXCL10 and IL-8/CXCL8 are potential novel biomarkers of warm autoimmune hemolytic anemia Branch DR, Leger RM, Sakac d, Yi Q, Duong T, Yeung RSM, Binnington B, Bloch EM 2022 Blood Adv View Researchers Basic research
Adjudicating the Diagnosis of Immune Thrombocytopenia in a Clinical Research Study Gabe C, Mahamad S, John M, Duncan J, Kelton J, Arnold D 2023 TH Open View Researchers Clinical research
Hepatitis B Blood Donor Screening Data: An Under-Recognized Resource for Canadian Public Health Surveillance O’Brien SF, Reedman CN, Osiowy C, Bolotin S, Yi Q-L, Lourenço L, Lewin A, Binka M, Caffrey N, Drews SJ 2023 Viruses View Researchers Clinical research
Rapid potency assessment of autologous peripheral blood stem cells by intracellular flow cytometry: the PBSC-IL-3-pSTAT5 assay Simard C, Fournier D, Pineault N, Trépanier P 2022 Cytotherapy View Researchers New or improved product or process
A role for red cell clearance in antibody-mediated inhibition of erythrocyte alloimmunization? Marjoram D, Cruz-Leal Y, Bernardo L, Lazarus AH 2017 ISBT Sci Ser View Researchers Basic research
Anti-A and anti-B: what are they and where do they come from? Branch DR 2015 Transfusion View Researchers Other
Bacteria can proliferate in thawed cryoprecipitate stored at room temperature for longer than 4 h Ramirez-Arcos S, Jenkins C, Sheffield W 2017 Vox Sang View Researchers Basic research
Chapter 33: Synthesis of N-(4-Methoxybenzyl)-2-(α-d-glucopyranosyl) acetamide Roy R, Vidal S, Briard JG, Shiao TC, Ben RN 2015 Carbohydrate Chemistry: Proven Synthetic Methods, Volume 3 View Researchers Basic research
Comparison of methods for the purification of alpha-1 acid glycoprotein from human plasma McCurdy TR, Bhakta V, Eltringham-Smith LJ, Gataiance S, Fox-Robichaud AE, Sheffield WP 2011 J Biomed Biotechnol View Researchers Basic research
Dissociation of SERPINE1 mRNA from the translational repressor proteins Ago2 and TIA-1 upon platelet activation Corduan A, Ple H, Laffont B, Wallon T, Plante I, Landry P, Provost P 2015 Thromb Haemost View Researchers Basic research
Effect of texture of platelet bags on bacterial and platelet adhesion Hadjesfandiari N, Schubert P, Fallah Toosi S, Chen Z, Culibrk B, Ramirez-Arcos S, Devine DV, Brooks DE 2016 Transfusion View Researchers Basic research
Fanconi anemia proteins and their interacting partners: a molecular puzzle Kaddar T, Carreau M 2012 Anemia View Researchers Basic research