Our Research Publications
Updated November 2023
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Title | Authors | Year | Journal Sort descending | Link to Article | Intended Audience | Purpose |
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p38 mitogen-activated protein kinase regulates mitochondrial function and microvesicle release in riboflavin- and ultraviolet light–treated apheresis platelet concentrates | Chen Z, Schubert P, Bakkour S, Culibrk B, Busch MP, Devine DV | 2017 | Transfusion | View p38 mitogen-activated protein kinase regulates mitochondrial function and microvesicle release in riboflavin- and ultraviolet light–treated apheresis platelet concentrates | Researchers | Basic research |
Splitting versus lumping: reconsidering the definition of transfusion-related acute lung injury | Webert KE | 2015 | Transfusion | View Splitting versus lumping: reconsidering the definition of transfusion-related acute lung injury | Health care providers | Clinical research |
Transfusion reactions: a comparative observational study of blood components produced before and after implementation of semiautomated production from whole blood | Semple E, Bowes-Schmidt A, Yi QL, Shimla S, Devine DV | 2012 | Transfusion | View Transfusion reactions: a comparative observational study of blood components produced before and after implementation of semiautomated production from whole blood | Blood operators | New or improved product or process |
Utility of cross-matched platelet transfusions in patients with hypoproliferative thrombocytopenia: a systematic review | Vassallo RR, Fung M, Rebulla P, Duquesnoy R, Saw CL, Slichter SJ, Tanael S, Shehata N, International Collaboration for Guideline Development Implementation Evaluation for Transfusion Therapies Collaborators | 2013 | Transfusion | View Utility of cross-matched platelet transfusions in patients with hypoproliferative thrombocytopenia: a systematic review | Researchers | Clinical research |
International validation of harmonized definitions for complications of blood donations | Land KJ, Townsend M, Goldman M, Whitaker BI, Perez GE, Wiersum-Osselton JC | 2018 | Transfusion | View International validation of harmonized definitions for complications of blood donations | Blood operators | New or improved product or process |
Variations in RBC and frozen plasma utilization rates across 62 Ontario community hospitals | Qiang JK, Thompson T, Callum J, Pinkerton P, Lin Y | 2019 | Transfusion | View Variations in RBC and frozen plasma utilization rates across 62 Ontario community hospitals | Health care providers | Clinical research |
The association between platelet transfusions and mortality in patients with critical illness | Ning S, Liu Y, Barty R, Cook R, Rochwerg B, Iorio A, Warkentin TE, Heddle NM, Arnold DM | 2019 | Transfusion | View The association between platelet transfusions and mortality in patients with critical illness | Researchers | Clinical research |
Pathogen reduction of whole blood: Supplementing fibrinogen partly corrects clot formation in a massive transfusion model | Arbaeen AF, Schubert P, Sheffield WP, Devine DV | 2021 | Transfusion | View Pathogen reduction of whole blood: Supplementing fibrinogen partly corrects clot formation in a massive transfusion model | Researchers | New or improved product or process |
Antigen copy number and antibody dose can determine the outcome of erythrocyte alloimmunization inducing either antibody-mediated immune suppression or enhancement in a murine model | Wabnitz H, Cruz-Leal Y, Lazarus AH | 2023 | Transfusion | View Antigen copy number and antibody dose can determine the outcome of erythrocyte alloimmunization inducing either antibody-mediated immune suppression or enhancement in a murine model | Researchers | Basic research |
A monoclonal antibody with anti-D–like activity in murine immune thrombocytopenia requires Fc domain function for immune thrombocytopenia ameliorative effects | Yu X, Menard M, Seabright G, Crispin M, Lazarus AH | 2015 | Transfusion | View A monoclonal antibody with anti-D–like activity in murine immune thrombocytopenia requires Fc domain function for immune thrombocytopenia ameliorative effects | Researchers | Basic research |
Hepatitis E in Canadian blood donors | Fearon MA, O'Brien SF, Delage G, Scalia V, Bernier F, Bigham M, Weger S, Prabhu S, Andonov A | 2017 | Transfusion | View Hepatitis E in Canadian blood donors | Blood operators | Clinical research |
Residual risk of bacterial contamination of platelets: six years of experience with sterility testing | Ramirez-Arcos S, DiFranco C, McIntyre T, Goldman M | 2017 | Transfusion | View Residual risk of bacterial contamination of platelets: six years of experience with sterility testing | Researchers | New or improved product or process |
Transfusion-related lung injury in children: a case series and review of the literature | Lieberman L, Petraszko T, Yi QL, Hannach B, Skeate R | 2014 | Transfusion | View Transfusion-related lung injury in children: a case series and review of the literature | Health care providers | Clinical research |
Modeling rare blood in Canada | Blake JT, Clarke G | 2018 | Transfusion | View Modeling rare blood in Canada | Health care providers | New or improved product or process |
Isoagglutinin-reduced immunoglobulin retains efficacy in mouse models of immune thrombocytopenia and rheumatoid arthritis and is less likely to cause intravenous immunoglobulin–associated hemolysis | Cen SY, Branch DR | 2020 | Transfusion | View Isoagglutinin-reduced immunoglobulin retains efficacy in mouse models of immune thrombocytopenia and rheumatoid arthritis and is less likely to cause intravenous immunoglobulin–associated hemolysis | Researchers | Basic research |
Daudi cell stroma: An alternative to dithiothreitol to resolve daratumumab interference in pretransfusion testing | Tremblay T, Branch DR, Loubaki L | 2020 | Transfusion | View Daudi cell stroma: An alternative to dithiothreitol to resolve daratumumab interference in pretransfusion testing | Researchers | New or improved product or process |
Five novel FY null alleles associated with typing discrepancies | Vege S, Floch A, Lomas-Frances C, Clarke G, Westhoff CM | 2021 | Transfusion | View Five novel FY null alleles associated with typing discrepancies | Researchers | Benchmarking and standard setting |
Rejuvenated and safe: Freeze-dried plasma for the 21st century | Sheffield WP, V. Devine D | 2022 | Transfusion | View Rejuvenated and safe: Freeze-dried plasma for the 21st century | Health care providers | New or improved product or process |
Prevention of transfusion-transmitted syphilis by blood operators: How much is enough when transfusion-transmission has not been identified for decades? | Drews SJ | 2021 | Transfusion | View Prevention of transfusion-transmitted syphilis by blood operators: How much is enough when transfusion-transmission has not been identified for decades? | Blood operators | Benchmarking and standard setting |
Donor sex, pre-donation hemoglobin, and manufacturing affect CD71+ cells in red cell concentrates | Li W, William N, Acker JP | 2023 | Transfusion | View Donor sex, pre-donation hemoglobin, and manufacturing affect CD71+ cells in red cell concentrates | Researchers | Basic research |
How do we decide how representative our donors are for public health surveillance? | O'Brien SF, Drews SJ, Lewin A, Russell A, Davison K, Goldman M, International Society for Blood Transfusion Transfusion Transmitted Infectious Disease Working Party Surveillance Risk Assessment Policy Sub-group | 2022 | Transfusion | View How do we decide how representative our donors are for public health surveillance? | Researchers | Benchmarking and standard setting |
Cold-stored platelets are effective in an in vitro model of massive transfusion protocol assessed by rotational thromboelastometry | Zhao HQ, Serrano K, Culibrk B, Chen Z, Devine DV | 2022 | Transfusion | View Cold-stored platelets are effective in an in vitro model of massive transfusion protocol assessed by rotational thromboelastometry | Researchers | New or improved product or process |
Changes in blood center red blood cell distributions in the era of patient blood management: the trends for collection (TFC) study | Yazer MH, Jackson B, Beckman N, Chesneau S, Bowler P, Delaney M, Devine D, Field S, Germain M, Murphy MF, Sayers M, Shaz B, Shinar E, Takanashi M, Vassallo R, Wickenden C, Yahalom V, Land K, on behalf of the BEST Collaborative | 2016 | Transfusion | View Changes in blood center red blood cell distributions in the era of patient blood management: the trends for collection (TFC) study | Blood operators | New or improved product or process |
Internal medicine resident knowledge of transfusion medicine: results from the BEST-TEST international education needs assessment | Haspel RL, Lin Y, Mallick R, Tinmouth A, Cid J, Eichler H, Lozano M, van de Watering L, Fisher PB, Ali A, Parks E | 2014 | Transfusion | View Internal medicine resident knowledge of transfusion medicine: results from the BEST-TEST international education needs assessment | Health care providers | Other |
Optimal conditions for the performance of a monocyte monolayer assay | Tong TN, Burke-Murphy E, Sakac D, Pendergrast J, Cserti-Gazdewich C, Laroche V, Branch DR | 2016 | Transfusion | View Optimal conditions for the performance of a monocyte monolayer assay | Researchers | Basic research |
2-HG inhibits necroptosis by stimulating DNMT1-dependent hypermethylation of the RIP3 promoter | Yang Z, Jiang B, Wang Y, Ni H, Zhang J, Xia J, Shi M, Hung L, Ruan J, Mak T, Li Q, Han J | 2017 | Cell Rep | View 2-HG inhibits necroptosis by stimulating DNMT1-dependent hypermethylation of the RIP3 promoter | Researchers | Basic research |
A 13-question approach to resolving serological discrepancies in the transfusion medicine laboratory | Yudin J, Heddle NM | 2014 | Lab Med | View A 13-question approach to resolving serological discrepancies in the transfusion medicine laboratory | Health care providers | Clinical research |
QSAR accelerated discovery of potent ice recrystallization inhibitors | Briard JG, Fernandez M, De Luna P, Woo TK, Ben RN | 2016 | Sci Rep | View QSAR accelerated discovery of potent ice recrystallization inhibitors | Researchers | Basic research |
Co-administration of FVIII with IVIG reduces immune response to FVIII in hemophilia A mice | Afraz S, Stevic I, Matino D, Wen J, Atkinson H, Chan AKC, Hortelano G | 2022 | Sci Rep | View Co-administration of FVIII with IVIG reduces immune response to FVIII in hemophilia A mice | Researchers | Clinical research |
Deformability based cell sorting using microfluidic ratchets enabling phenotypic separation of leukocytes directly from whole blood | Guo Q, Duffy SP, Matthews K, Islamzada E, Ma H | 2017 | Sci Rep | View Deformability based cell sorting using microfluidic ratchets enabling phenotypic separation of leukocytes directly from whole blood | Researchers | New or improved product or process |
Small Molecule Ice Recrystallization Inhibitors Enable Freezing of Human Red Blood Cells with Reduced Glycerol Concentrations | Capicciotti CJ, Kurach JDR, Turner TR, Mancini RS, Acker JP, Ben RN | 2015 | Sci Rep | View Small Molecule Ice Recrystallization Inhibitors Enable Freezing of Human Red Blood Cells with Reduced Glycerol Concentrations | Researchers | New or improved product or process |
Small molecule ice recrystallization inhibitors mitigate red blood cell lysis during freezing, transient warming and thawing | Briard JG, Poisson JS, Turner TR, Capicciotti CJ, Acker JP, Ben RN | 2016 | Sci Rep | View Small molecule ice recrystallization inhibitors mitigate red blood cell lysis during freezing, transient warming and thawing | Researchers | New or improved product or process |
CD8(+) T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia | Qiu J, Liu X, Li X, Zhang X, Han P, Zhou H, Shao L, Hou Y, Min Y, Kong Z, Wang Y, Wei Y, Liu X, Ni H, Peng J, Hou M | 2016 | Sci Rep | View CD8(+) T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia | Researchers | Basic research |
Identification of an alpha-1 antitrypsin variant with enhanced specificity for factor XIa by phage display, bacterial expression, and combinatorial mutagenesis | Bhakta V, Hamada M, Nouanesengsy A, Lapierre J, Perruzza DL, Sheffield WP | 2021 | Sci Rep | View Identification of an alpha-1 antitrypsin variant with enhanced specificity for factor XIa by phage display, bacterial expression, and combinatorial mutagenesis | Researchers | Basic research |
In vitro assessment and phase I randomized clinical trial of anfibatide a snake venom derived anti-thrombotic agent targeting human platelet GPIb? | Li BX, Dai X, Xu XR, Adili R, Neves MAD, Lei X, Shen C, Zhu G, Wang Y, Zhou H, Hou Y, Ni T, Pasman Y, Yang Z, Qian F, Zhao Y, Gao Y, Liu J, Teng M, Marshall AH, Cerenzia EG, Li ML, Ni H | 2021 | Sci Rep | View In vitro assessment and phase I randomized clinical trial of anfibatide a snake venom derived anti-thrombotic agent targeting human platelet GPIb? | Researchers | Clinical research |
Revealing the diversity of extracellular vesicles using high-dimensional flow cytometry analyses | Marcoux G, Duchez A-C, Cloutier N, Provost P, Nigrovic PA, Boilard E | 2016 | Sci Rep | View Revealing the diversity of extracellular vesicles using high-dimensional flow cytometry analyses | Researchers | Basic research |
Prothrombin, alone or in complex concentrates or plasma, reduces bleeding in a mouse model of blood exchange-induced coagulopathy | Eltringham-Smith LJ, Yu R, Qadri SM, Wang Y, Bhakta V, Pryzdial EL, Crosby JR, Ni H, Sheffield WP | 2019 | Sci Rep | View Prothrombin, alone or in complex concentrates or plasma, reduces bleeding in a mouse model of blood exchange-induced coagulopathy | Researchers | Basic research |
A biochemical network can control formation of a synthetic material by sensing numerous specific stimuli | Hun Yeon J, Chan KYT, Wong T-C, Chan K, Sutherland MR, Ismagilov RF, Pryzdial ELG, Kastrup CJ | 2015 | Sci Rep | View A biochemical network can control formation of a synthetic material by sensing numerous specific stimuli | Researchers | Basic research |
Accelerated apoptotic death and in vivo turnover of erythrocytes in mice lacking functional mitogen- and stress-activated kinase MSK1/2 | Lang E, Bissinger R, Fajol A, Salker MS, Singh Y, Zelenak C, Ghashghaeinia M, Gu S, Jilani K, Lupescu A, Reyskens KM, Ackermann TF, Foller M, Schleicher E, Sheffield WP, Arthur JS, Lang F, Qadri SM | 2015 | Sci Rep | View Accelerated apoptotic death and in vivo turnover of erythrocytes in mice lacking functional mitogen- and stress-activated kinase MSK1/2 | Researchers | Basic research |
Carbohydrate-based ice recrystallization inhibitors increase infectivity and thermostability of viral vectors | Ghobadloo SM, Balcerzak AK, Gargaun A, Muharemagic D, Mironov GG, Capicciotti CJ, Briard JG, Ben RN, Berezovski MV | 2014 | Sci Rep | View Carbohydrate-based ice recrystallization inhibitors increase infectivity and thermostability of viral vectors | Researchers | Basic research |
Cardiorespiratory pathogenesis of sickle cell disease in a mouse model | Ren J, Ding X, Trudel M, Greer JJ, MacLean JE | 2017 | Sci Rep | View Cardiorespiratory pathogenesis of sickle cell disease in a mouse model | Researchers | Basic research |
Correction of haemorrhagic shock-associated coagulopathy and impaired haemostasis by plasma, prothrombin complex concentrates or an activated protein C-targeted DNA aptamer in mice | Eltringham-Smith LJ, Meixner SC, Pryzdial ELG, Sheffield WP | 2023 | Sci Rep | View Correction of haemorrhagic shock-associated coagulopathy and impaired haemostasis by plasma, prothrombin complex concentrates or an activated protein C-targeted DNA aptamer in mice | Researchers | Basic research |
IVIG regulates the survival of human but not mouse neutrophils | Schneider C, Wicki S, Graeter S, Timcheva TM, Keller CW, Quast I, Leontyev D, Djoumerska-Alexieva IK, Kasermann F, Jakob SM, Peyta D, Branch D, Cummings J, Kaufmann T, Simon H, Von Gunten S | 2017 | Sci Rep | View IVIG regulates the survival of human but not mouse neutrophils | Researchers | Basic research |
Selection and characterization of a DNA aptamer inhibiting coagulation factor XIa | Donkor DA, Bhakta V, Eltringham-Smith LJ, Stafford AR, Weitz JI, Sheffield WP | 2017 | Sci Rep | View Selection and characterization of a DNA aptamer inhibiting coagulation factor XIa | Researchers | Basic research |
A bioinformatics approach to identify natural autoantibodies from healthy blood donors' sera reactive with the HCV NS5A-derived peptide by immunoassay | Vasiljevic N, Veljkovic N, Kosec T, Ma XZ, Glisic S, Prljic J, Vujicic AD, Markovic L, Branch DR | 2011 | Viral Immunol | View A bioinformatics approach to identify natural autoantibodies from healthy blood donors' sera reactive with the HCV NS5A-derived peptide by immunoassay | Researchers | Basic research |
Gender and BCR-ABL transcript type are correlated with molecular response to imatinib treatment in patients with chronic myeloid leukemia | Lin HX, Sjaarda J, Dyck J, Stringer R, Hillis C, Harvey M, Carter R, Ainsworth P, Leber B, Pare G, Sadikovic B | 2016 | Eur J Haematol | View Gender and BCR-ABL transcript type are correlated with molecular response to imatinib treatment in patients with chronic myeloid leukemia | Researchers | Clinical research |
Utilization of a surgical database to provide care and assess perioperative treatment and outcomes in patients with bleeding disorders | Olasupo OO, Haddix C, Nakar C, Maahs J, Greist A, Ghafoor A, Donfield SM, Iorio A, Shapiro AD | 2022 | Eur J Haematol | View Utilization of a surgical database to provide care and assess perioperative treatment and outcomes in patients with bleeding disorders | Health care providers | Benchmarking and standard setting |
T cell-mediated autoimmunity in immune thrombocytopenia | Vrbensky JR, Nazy I, Clare R, Larché M, Arnold DM | 2022 | Eur J Haematol | View T cell-mediated autoimmunity in immune thrombocytopenia | Researchers | Clinical research |
Antibody binding to megakaryocytes in vivo in patients with immune thrombocytopenia | Arnold DM, Nazi I, Toltl LJ, Ross C, Ivetic N, Smith JW, Liu Y, Kelton JG | 2015 | Eur J Haematol | View Antibody binding to megakaryocytes in vivo in patients with immune thrombocytopenia | Researchers | Clinical research |
A blinded study of bone marrow examinations in patients with primary immune thrombocytopenia | Mahabir VK, Ross C, Popovic S, Sur ML, Bourgeois J, Lim W, George JN, Wang G, Cook RJ, Toltl LJ, Nazi I, Kelton JG, Arnold DM | 2013 | Eur J Haematol | View A blinded study of bone marrow examinations in patients with primary immune thrombocytopenia | Health care providers | Clinical research |