Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Quality of Red Blood Cells Isolated from Umbilical Cord Blood Stored at Room Temperature Zhurova M, Akabutu J, Acker J 2012 J Blood Transfus View Researchers New or improved product or process
Process improvement by eliminating mixing of whole blood units after an overnight hold prior to component production using the buffy coat method Mastronardi C, Schubert P, Levin E, Bhakta V, Yi QL, Hansen A, Stewart T, Jenkins C, Lefresne W, Sheffield W, Acker JP 2013 J Blood Transfus View Blood operators New or improved product or process
Progress in RNAi-mediated Molecular Therapy of Acute and Chronic Myeloid Leukemia Landry B, Valencia-Serna J, Gul-Uludag H, Jiang X, Janowska-Wieczorek A, Brandwein J, Uludag H 2015 Mol Ther Nucleic Acids View Researchers Other
Progressive development of polycystic kidney disease in the mouse model expressing Pkd1 extracellular domain Kurbegovic A, Trudel M 2013 Hum Mol Genet View Researchers Basic research
Quality Control of Automated Cell Counters Cembrowski GS, Clarke G 2015 Clin Lab Med View Health care providers Other
The Platelet Storage Lesion Devine DV, Serrano K 2010 Clin Lab Med View Blood operators Other
Raman spectroscopy of stored red blood cells: evaluating clinically-relevant biochemical markers in donated blood Atkins CG, Buckley K, Chen D, Schulze HG, Devine DV, Blades MW, Turner RFB 2015 Clin Biomed Spectrosc Imag IV View Researchers New or improved product or process
Synergistic effects of liposomes, trehalose, and hydroxyethyl starch for cryopreservation of human erythrocytes Stoll C, Holovati JL, Acker JP, Wolkers WF 2012 Biotechnol Prog View Researchers New or improved product or process
Rapid removal of glycerol from frozen-thawed red blood cells Lusianti RE, Benson JD, Acker JP, Higgins AZ 2013 Biotechnol Prog View Researchers New or improved product or process
Red blood cell antibody-induced anemia causes differential degrees of tissue hypoxia in kidney and brain Mistry N, Mazer CD, Sled JG, Lazarus AH, Cahill LS, Solish M, Zhou Y-Q, Romanova N, Hare AGM, Doctor A, Fisher JA, Brunt KR, Simpson JA, Hare GMT 2018 Am J Physiol Regul Integr Comp Physiol View Researchers Basic research
Red blood cell antibody induced anemia causes differential degrees of tissue hypoxia in kidney and brain Mistry N, Mazer CD, Sled JG, Lazarus AH, Cahill LS, Solish M, Zhou Y-Q, Romanova N, Hare AG, Doctor A, Fisher JA, Brunt KR, Simpson JA, Hare GMT 2018 Am J Physiol Regul Integr Comp Physiol View Researchers Basic research
Red Cell, Platelet and White Cell Antigens Webert KE, Arnold DM, Chan HWH, Smith JW, Heddle NM, Kelton JG 2013 Wintrobe's Clinical Hematology View Health care providers Other
Relaxin receptor antagonist AT-001 synergizes with docetaxel in androgen-independent prostate xenografts Neschadim A, Pritzker LB, Pritzker KP, Branch DR, Summerlee AJ, Trachtenberg J, Silvertown JD 2014 Endocr Relat Cancer View Researchers Basic research
Research with Blood Donated to Blood Banking Organizations Reis NM 2013 Health Law Review View Other Other
Rights and interests in human bodies and biological materials Toews M, Caulfield T, Nelson E, Ogbogu U, Hartell D 2015 Canadian National Transplant Research Program Fast Policy Facts: Human Bodies and Biological Materials View Other Other
Risk factors and impact of major bleeding in critically ill patients receiving heparin thromboprophylaxis Lauzier F, Arnold DM, Rabbat C, Heels-Ansdell D, Zarychanski R, Dodek P, Ashley BJ, Albert M, Khwaja K, Ostermann M, Skrobik Y, Fowler R, McIntyre L, Nates JL, Karachi T, Lopes RD, Zytaruk N, Finfer S, Crowther M, Cook D 2013 Intensive Care Med View Health care providers Clinical research
Efficacy and safety of tranexamic acid in acute traumatic brain injury: a systematic review and meta-analysis of randomized-controlled trials Lawati KA, Sharif S, Maqbali SA, Rimawi HA, Petrosoniak A, Belley-Cote EP, Sharma SV, Morgenstern J, Fernando SM, Owen JJ, Zeller M, Quinlan D, Alhazzani W, Rochwerg B 2021 Intensive Care Med Researchers Clinical research
Validation of administrative database codes for acute kidney injury in kidney transplant recipients Molnar AO, van Walraven C, McArthur E, Fergusson D, Garg AX, Knoll G 2016 Can J Kidney Health Dis View Regulators New or improved product or process
Risk of acute kidney injury in patients randomized to a restrictive versus liberal approach to red blood cell transfusion in cardiac surgery: a substudy protocol of the transfusion requirements in cardiac surgery III noninferiority trial Garg AX, Shehata N, McGuinness S, Whitlock R, Fergusson D, Wald R, Parikh C, Bagshaw SM, Khanykin B, Gregory A, Syed S, Hare GMT, Cuerden MS, Thorpe KE, Hall J, Verma S, Roshanov PS, Sontrop JM, Mazer CD 2018 Can J Kidney Health Dis View Researchers Clinical research
Risk of serious gastrointestinal bleeding in living kidney donors Thomas SM, Lam NN, Huang A, Nash DM, Prasad GV, Knoll GA, Koval JJ, Lentine KL, Kim SJ, Alam A, Lok CE, Treleaven DJ, Garg AX 2014 Clin Transplant View Health care providers Clinical research
Risks, benefits and the role of stakeholders in pathogen reduction technology Newbold KB, Heddle NM, Lane SJ, Arnold E, Eyles J, Webert K 2014 Health Risk Soc View Other Other
Glycoprotein V is a relevant immune target in patients with immune thrombocytopenia Vollenberg R, Jouni R, Norris PAA, Burg-Roderfeld M, Cooper N, Rummel MJ, Bein G, Marini I, Bayat B, Burack R, Lazarus AH, Bakchoul T, Sachs UJ 2019 Haematologica View Researchers Basic research
FcgammaRI and FcgammaRIII on splenic macrophages mediate phagocytosis of anti-glycoprotein IIb/IIIa autoantibody-opsonized platelets in immune thrombocytopenia Norris PAA, Segel GB, Burack WR, Sachs UJ, Lissenberg-Thunnissen SN, Vidarsson G, Bayat B, Cserti-Gazdewich CM, Callum J, Lin Y, Branch D, Kapur R, Semple JW, Lazarus AH 2021 Haematologica View Researchers Basic research
Fc?RI and FC?RIII on splenic macrophages mediate phagocytosis of anti-glycoprotein IIb/III autoantibody-opsonized platelets in immune thrombocytopenia Norris PAA, Segel GB, Burack WR, Sachs UJ, Lissenberg-Thunnissen SN, Vidarsson G, Bayat B, Cserti-Gazdewich CM, Callum J, Lin Y, Branch D, Kapur R, Semple JW, Lazarus AH 2020 Haematologica View Researchers Basic research
Human leukocyte antigen-G upregulates immunoglobulin-like transcripts and corrects dysfunction of immune cells in immune thrombocytopenia Li X, Sheng Z, Sun Y, Wang Y, Xu M, Zhang Z, Li H, Shao L, Zhang Y, Yu J, Ma C, Gao C, Hou M, Ni H, Peng J, Ma J, Feng Q 2020 Haematologica View Researchers Basic research
Severe platelet desialylation in a patient with glycoprotein Ib/IX antibody-mediated immune thrombocytopenia and fatal pulmonary hemorrhage Li J, Callum JL, Lin Y, Zhou Y, Zhu G, Ni H 2014 Haematologica View Researchers Clinical research
Targeting FcRs to treat antibody-dependent autoimmunity Yu X, Lazarus AH 2016 Autoimmun Rev View Researchers Other
Small molecule phagocytosis inhibitors for immune cytopenias Neschadim A, Kotra LP, Branch DR 2016 Autoimmun Rev View Researchers Basic research
Solving the dilemma of prevention of red cell alloimmunization Branch DR 2012 Immunotherapy View Researchers Other
Structure-activity relationships of pyrazole derivatives as potential therapeutics for immune thrombocytopenias Purohit MK, Chakka SK, Scovell I, Neschadim A, Bello AM, Salum N, Katsman Y, Bareau MC, Branch DR, Kotra LP 2014 Bioorg Med Chem View Researchers Basic research
Synthesis of peptides and glycopeptides with polyproline II helical topology as potential antifreeze molecules Corcilius L, Santhakumar G, Stone RS, Capicciotti CJ, Joseph S, Matthews JM, Ben RN, Payne RJ 2013 Bioorg Med Chem View Researchers Basic research
Subarachnoid hemorrhage admissions retrospectively identified using a prediction model English SW, McIntyre L, Fergusson D, Turgeon A, dos Santos MP, Lum C, Chassé M, Sinclair J, Forster A, van Walraven C 2016 Neurology View Health care providers Clinical research
Suicidal death of erythrocytes in cancer and its chemotherapy: A potential target in the treatment of tumor-associated anemia Lang E, Bissinger R, Qadri SM, Lang F 2017 Int J Cancer View Researchers Basic research
Synthesis and evaluation of linear CuAAC-oligomerized antifreeze neo-glycopeptides van der Wal S, Capicciotti CJ, Rontogianni S, Ben RN, Liskamp RMJ 2014 MedChemComm View Researchers Basic research
Aspirin nonsensitivity in patients with vascular disease: Assessment by light transmission aggregometry (aspirin nonsensitivity in vascular patients) Khan H, Zamzam A, Gallant RC, Syed MH, Rand ML, Ni H, Forbes TL, Al-Omran M, Qadura M 2021 Res Pract Thromb Haemost View Researchers Clinical research
Vaccine-induced immune thrombotic thrombocytopenia presenting with normal platelet count Page D, Zhu N, Sawler D, Sun HW, Turley E, Pai M, Wu C 2021 Res Pract Thromb Haemost View Researchers Clinical research
External qualification of the Web-Accessible Population Pharmacokinetic Service-Hemophilia (WAPPS-Hemo) models for octocog alfa using real patient data Chelle P, Hajducek D, Mahdi M, Young S, Iorio A, Silvertown J, Edginton A 2021 Res Pract Thromb Haemost View Researchers New or improved product or process
Systematic review of fondaparinux for heparin-induced thrombocytopenia: When there are no randomized controlled trials Linkins L, Hu G, Warkentin TE 2018 Res Pract Thromb Haemost View Researchers Clinical research
The impact of extended half-life factor concentrates on patient reported health outcome measures in persons with hemophilia A and hemophilia B Sun HL, Yang M, Poon MC, Lee A, Robinson KS, Sholzberg M, Wu J, Iorio A, Blanchette V, Carcao M, Klaassen RJ, Jackson S 2021 Res Pract Thromb Haemost View Researchers Clinical research
High-dose IVIG plus cangrelor platelet "anesthesia" during urgent heparin-CPB in a patient with recent SRA-negative HIT-thrombosis with persisting platelet-activating antibodies Koster A, Nazy I, Birschmann IE, Smith JW, Sheppard JI, Warkentin TE 2020 Res Pract Thromb Haemost View Health care providers Clinical research
Antiviral anticoagulation Pryzdial ELG, Sutherland MR, Lin BH, Horwitz M 2020 Res Pract Thromb Haemost View Researchers Basic research
Prevalence of selected bleeding and thrombotic events in persons with hemophilia versus the general population: A scoping review Shapiro AD, Hardesty BM, Peyvandi F, Iorio A 2023 Res Pract Thromb Haemost View Researchers Clinical research
Using pharmacokinetics for tailoring prophylaxis in people with hemophilia switching between clotting factor products: A scoping review Yu JK, Iorio A, Edginton AN, Wapps co?investigators 2019 Res Pract Thromb Haemost View Researchers Clinical research
Prehospital fresh frozen plasma: Universal life saver or treatment in search of a target population? Makris M, Iorio A 2018 Res Pract Thromb Haemost View Health care providers Clinical research
Magnetic resonance imaging in boys with severe hemophilia A: Serial and end-of-study findings from the Canadian Hemophilia Primary Prophylaxis Study Stimec J, Dover S, Pullenayegum E, Blanchette VS, Doria AS, Feldman BM, Carcao M, Rivard GE, Israels SJ, Chan AK, Steele M, Cloutier S, Klaassen RJ, Price VE, Sinha R, Laferriere N, Paradis E, Wu JKM, Babyn P 2021 Res Pract Thromb Haemost View Researchers Clinical research
Proceedings of the immune thrombocytopenia summit: new concepts in mechanisms, diagnosis, and management Mahamad S, Modi D, Al-Samkari H, Cuker A, Despotovic JM, Italiano JE, Lambert MP, Lee EJ, Rondina MT, Sholzberg M, Kruse C, Larché M, Nazy I, Miller MS, Arnold DM 2023 Res Pract Thromb Haemost View Health care providers Clinical research
The association between platelet transfusions and bleeding in critically ill patients with thrombocytopenia Arnold DM, Lauzier F, Albert M, Williamson D, Li N, Zarychanski R, Doig C, McIntyre L, Freitag A, Crowther M, Saunders L, Clarke F, Bellomo R, Qushmaq I, Lopes R, Heels-Ansdell D, Webert K, Cook D 2017 Res Pract Thromb Haemost View Researchers Clinical research
Focusing in on use of pharmacokinetic profiles in routine hemophilia care Croteau SE, Callaghan MU, Davis J, Dunn AL, Guerrera M, Khan O, Neufeld EJ, Raffini LJ, Recht M, Wang M, Iorio A 2018 Res Pract Thromb Haemost View Health care providers Clinical research
The Effect of Age and Type of Media on Growth Kinetics of Human Amniotic Fluid Stem cells Borzou B, Mehrabani D, Zare S, Zamani-Pereshkaft M, Acker JP 2020 Biopreserv Biobank View Researchers Basic research
The effect of liposome treatment on the quality of hypothermically stored red blood cells Stadnick H, Stoll C, Wolkers WF, Acker JP, Holovati JL 2011 Biopreserv Biobank View Researchers New or improved product or process