Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Fondaparinux for treatment of heparin-induced thrombocytopenia: too good to be true? Warkentin TE 2017 J Am Coll Cardiol View Health care providers Clinical research
Defocused Spatially Offset Raman Spectroscopy in Media of Different Optical Properties for Biomedical Applications Using a Commercial Spatially Offset Raman Spectroscopy Device Vardaki MZ, Devine DV, Serrano K, Simantiris N, Blades MW, Piret JM, Turner RFB 2020 Appl Spectrosc View Researchers New or improved product or process
Fully automated decomposition of raman spectra into individual Pearson's type VII distributions applied to biological and biomedical samples Schulze HG, Atkins CG, Devine DV, Blades MW, Turner RF 2015 Appl Spectrosc View Researchers Basic research
Further evidence that paroxysmal nocturnal haemoglobinuria is a disorder of defective cell membrane lipid rafts Ratajczak MZ, Borkowska S, Mierzejewska K, Kucia M, Mendek-Czajkowska E, Suszynska M, Sharma VA, Deptala A, Song W, Platzbecker U, Larratt L, Janowska-Wieczorek A, Maciejewski J, Ratajczak J 2015 J Cell Mol Med View Researchers Basic research
Phosphatidylserine externalization and procoagulant activation of erythrocytes induced by Pseudomonas aeruginosa virulence factor pyocyanin Qadri SM, Donkor DA, Bhakta V, Eltringham-Smith LJ, Dwivedi DJ, Moore JC, Pepler L, Ivetic N, Nazi I, Fox-Robichaud AE, Liaw PC, Sheffield WP 2016 J Cell Mol Med View Researchers Basic research
Fusion of the C-terminal triskaidecapeptide of hirudin variant 3 to alpha1-proteinase inhibitor M358R increases the serpin-mediated rate of thrombin inhibition Roddick LA, Bhakta V, Sheffield W 2013 BMC Biochem View Researchers Basic research
The complete N-terminal extension of heparin cofactor II is required for maximal effectiveness as a thrombin exosite 1 ligand Boyle AJ, Roddick LA, Bhakta V, Lambourne MD, Junop MS, Liaw PC, Weitz JI, Sheffield WP 2013 BMC Biochem View Researchers Basic research
Fusion to human serum albumin extends the circulatory half-life and duration of antithrombotic action of the Kunitz protease inhibitor domain of Protease Nexin 2 Sheffield WP, Eltringham-Smith LJ, Bhakta V 2018 Cell Physiol Biochem View Researchers Basic research
N-ethylmaleimide activates a Cl(-)-independent component of K(+) flux in mouse erythrocytes Shmukler BE, Hsu A, Alves J, Trudel M, Rust MB, Hubner CA, Rivera A, Alper SL 2013 Blood Cells Mol Dis View Researchers Basic research
Genome-wide association study of erythrocyte density in sickle cell disease patients Ilboudo Y, Bartolucci P, Rivera A, Sedzro JC, Beaudoin M, Trudel M, Alper SL, Brugnara C, Galacteros F, Lettre G 2017 Blood Cells Mol Dis View Researchers Basic research
Glucagon-like peptide 1 receptor activation attenuates platelet aggregation and thrombosis Cameron-Vendrig A, Reheman A, Siraj MA, Xu XR, Wang Y, Lei X, Afroze T, Shikatani E, El-Mounayri O, Noyan H, Weissleder R, Ni H, Husain M 2016 Diabetes View Researchers Basic research
Haematological problems in obstetrics Rodger M, Sheppard D, Gandara E, Tinmouth A 2015 Best Pract Res Clin Obstet Gynaecol View Health care providers Other
HbM methaemoglobinaemia as a rare case of early neonatal benign cyanosis Elboraee MS, Clarke G, Belletrutti MJ, Escoredo S 2015 BMJ Case Reports View Health care providers Clinical research
Hematopoietic Stem Cell Mobilization and Homing after Transplantation: The Role of MMP-2, MMP-9, and MT1-MMP Shirvaikar N, Marquez-Curtis LA, Janowska-Wieczorek A 2012 Biochem Res Int View Researchers Basic research
Hemoglobin Area and Time Index Above 90 g/L are Associated with Improved 6-Month Functional Outcomes in Patients with Severe Traumatic Brain Injury Griesdale DE, Sekhon MS, Menon DK, Lavinio A, Donnelly J, Robba C, Sekhon IS, Taylor A, Henderson WR, Turgeon AF, Gupta AK 2014 Neurocrit Care View Health care providers Clinical research
The potential role of a turbidimetric heart-type fatty acid-binding protein assay to aid in the interpretation of persistently elevated, non-changing, cardiac troponin I concentrations Kavsak PA, Ainsworth C, Arnold DM, Scott T, Clark L, Ivica J, Mackett K, Whitlock R, Worster A 2018 Clin Biochem View Researchers Basic research
Hemoglobin C in a patient with sickle cell anemia: Transfusion-acquired SC disease Estey MP, Capote KR, Barakauskas VE, Clarke G, Higgins T 2015 Clin Biochem View Health care providers Clinical research
Ironing out frequent blood donation Devine DV 2019 Lancet Haematol View Researchers New or improved product or process
Red blood cell processing methods and in-hospital mortality: a transfusion registry cohort study Heddle NM, Arnold DM, Acker JP, Liu Y, Barty RL, Eikelboom JW, Webert KE, Hsia CC, O'Brien SF, Cook RJ 2016 Lancet Haematol View Researchers Clinical research
Perioperative oral eltrombopag versus intravenous immunoglobulin in patients with immune thrombocytopenia: a non-inferiority, multicentre, randomised trial Arnold DM, Heddle NM, Cook RJ, Hsia C, Blostein M, Jamula E, Sholzberg M, Lin Y, Kassis J, Larratt L, Tinmouth A, Amini S, Schipperus M, Lim W, Vishnu P, Warner M, Carruthers J, Li N, Lane S, Kelton JG 2020 Lancet Haematol View Health care providers Clinical research
Red blood cell storage and in-hospital mortality: a secondary analysis of the INFORM randomised controlled trial Cook RJ, Heddle NM, Lee KA, Arnold DM, Crowther MA, Devereaux PJ, Ellis M, Figueroa P, Kurz A, Roxby D, Sessler DI, Sharon Y, Sobieraj-Teague M, Warkentin TE, Webert KE, Barty R, Liu Y, Eikelboom JW 2017 Lancet Haematol View Health care providers Clinical research
Effects of the COVID-19 pandemic on supply and use of blood for transfusion Stanworth SJ, New HV, Apelseth TO, Brunskill S, Cardigan R, Doree C, Germain M, Goldman M, Massey E, Prati D, Shehata N, So-Osman C, Thachil J 2020 Lancet Haematol View Health care providers Clinical research
High-dose dexamethasone compared with prednisone for previously untreated primary immune thrombocytopenia: a systematic review and meta-analysis Mithoowani S, Gregory-Miller K, Goy J, Miller MC, Wang G, Noroozi N, Kelton JG, Arnold DM 2016 Lancet Haematol View Researchers Clinical research
Rituximab plus standard of care for treatment of primary immune thrombocytopenia: a systematic review and meta-analysis Chugh S, Darvish-Kazem S, Lim W, Crowther MA, Ghanima W, Wang G, Heddle NM, Kelton JG, Arnold DM 2015 Lancet Haematol View Health care providers Clinical research
Vaccine-induced immune thrombotic thrombocytopenia Klok FA, Pai M, Huisman MV, Makris M 2022 Lancet Haematol View Researchers Clinical research
Tailored frequency-escalated primary prophylaxis for severe haemophilia A: results of the 16-year Canadian Hemophilia Prophylaxis Study longitudinal cohort Feldman BM, Rivard GE, Babyn P, Wu JKM, Steele M, Poon M-C, Card RT, Israels SJ, Laferriere N, Gill K, Chan AK, Carcao M, Klaassen RJ, Cloutier S, Price VE, Dover S, Blanchette VS 2018 Lancet Haematol View Health care providers Clinical research
What Goes Up, Must Go Down? Parker MJ 2018 Pediatr Crit Care Med View Researchers Clinical research
Neuroimaging in sepsis: panacea or Pandora's box? Parker MJ, Kissoon N 2017 Pediatr Crit Care Med View Health care providers Clinical research
High-quality randomized controlled trials in pediatric critical care: a survey of barriers and facilitators Duffett M, Choong K, Foster J, Meade M, Menon K, Parker M, Cook DJ 2017 Pediatr Crit Care Med View Researchers Clinical research
Hope for the Best, but Prepare for the Worst Blake J, Nemergut EC 2014 Anesth Analg View Researchers New or improved product or process
Red cell transfusion-associated hemolysis in cardiac surgery: an observational cohort study Karkouti K, Callum J, Acker JP, Yip P, Rao V 2017 Anesth Analg View Researchers Clinical research
How to succeed in research during medical training: a qualitative study Alak A, Jerzak KJ, Quirt JA, Lane SJ, Miller PA, Haider S, Arnold DM 2014 Clin Invest Med View Health care providers Clinical research
How we treat thrombotic thrombocytopenic purpura: Results of a Canadian TTP practice survey Patriquin CJ, Clark WF, Pavenski K, Arnold DM, Rock G, Foley SR, for the Canadian Apheresis Group 2016 J Clin Apher View Health care providers Clinical research
Human Endothelial Colony-Forming Cells Protect against Acute Kidney Injury: Role of Exosomes Burger D, Viñas JL, Akbari S, Dehak H, Knoll W, Gutsol A, Carter A, Touyz RM, Allan DS, Burns KD 2015 Am J Pathol View Researchers Basic research
Hydroxyethyl starch supplemented with ice recrystallization inhibitors greatly improves cryopreservation of human red blood cells Poisson J, Briard J, Turner TR, Acker J, Ben R 2017 BioProcessing Journal View Researchers Basic research
Ice recrystallization inhibitors: from biological antifreezes to small molecules Capicciotti CJ, Doshi M, Ben RN 2013 Recent developments in the study of recrystallization View Researchers Basic research
Identification of potential protein quality markers in pathogen inactivated and gamma-irradiated red cell concentrates Chen D, Schubert P, Devine DV 2017 Proteomics Clin Appl View Researchers Basic research
Peculiarities of studying the effects of pathogen reduction technologies on platelets Osman A, Hitzler WE, Provost P 2016 Proteomics Clin Appl View Researchers Basic research
Protein translation occurs in platelet concentrates despite riboflavin/UV light pathogen inactivation treatment Schubert P, Culibrk B, Karwal S, Goodrich RP, Devine DV 2016 Proteomics Clin Appl View Researchers Basic research
Safety and efficacy of self-administered romiplostim in patients with immune thrombocytopenia: Results of an integrated database of five clinical trials Kuter DJ, Arnold DM, Rodeghiero F, Janssens A, Selleslag D, Bird R, Newland A, Mayer J, Wang K, Olie R 2020 Am J Hematol View Researchers Clinical research
Hemolysis after high-dose intravenous immunoglobulin: An under-appreciated sequelae Branch DR, Almizraq RJ, Bussel JB 2022 Am J Hematol View Researchers Basic research
The platelet serotonin-release assay Warkentin TE, Arnold DM, Nazi I, Kelton JG 2015 Am J Hematol View Health care providers Clinical research
Limitations of the particle immunofiltration assay test for diagnosis of heparin-induced thrombocytopenia Warkentin TE, Cook RJ, Greinacher A 2020 Am J Hematol View Health care providers New or improved product or process
Venous limb gangrene and pulseless electrical activity (PEA) cardiac arrest during management of deep-vein thrombosis and progressive limb ischemic necrosis following vascular surgery Avram AT, Blostein MD, Hirsch AM, Warkentin TE 2020 Am J Hematol View Health care providers Clinical research
Fostamatinib for the treatment of adult persistent and chronic immune thrombocytopenia: Results of two phase 3, randomized, placebo?controlled trials Bussel J, Arnold DM, Grossbard E, Mayer J, Treliski J, Homenda W, Hellmann A, Windyga J, Sivcheva L, Khalafallah AA, Zaja F, Cooper N, Markovtsov V, Zayed H, Duliege AM 2018 Am J Hematol View Health care providers Clinical research
Immune thrombocytopenia (ITP) World Impact Survey (I-WISh): Impact of ITP on health-related quality of life Cooper N, Kruse A, Kruse C, Watson S, Morgan M, Provan D, Ghanima W, Arnold DM, Tomiyama Y, Santoro C, Michel M, Laborde S, Lovrencic B, Hou M, Bailey T, Taylor-Stokes G, Haenig J, Bussel JB 2021 Am J Hematol View Researchers Clinical research
Acute thrombocytopenia suggesting thrombotic microangiopathy Venier LM, Patriquin CJ, Warkentin TE 2022 Am J Hematol View Health care providers Clinical research
Serotonin-release assay-positive but platelet factor 4-dependent enzyme-immunoassay negative: HIT or not HIT? Warkentin TE, Smythe MA, Ali MA, Aslam N, Sheppard JI, Smith JW, Moore JC, Arnold DM, Nazy I 2021 Am J Hematol View Researchers Clinical research
Sialidase inhibition to increase platelet counts: A new treatment option for thrombocytopenia Jansen AJG, Peng J, Zhao H-G, Hou M, Ni H 2015 Am J Hematol View Health care providers Clinical research
Understanding pulse oximetry in hematology patients: Hemoglobinopathies, racial differences, and beyond Patterson S, Sandercock N, Verhovsek M 2022 Am J Hematol View Health care providers Clinical research