Our Research Publications
Updated November 2023
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Title | Authors | Year | Journal Sort descending | Link to Article | Intended Audience | Purpose |
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Megakaryocyte apoptosis in immune thrombocytopenia | Vrbensky JR, Nazy I, Toltl LJ, Ross C, Ivetic N, Smith JW, Kelton JG, Arnold DM | 2018 | Platelets | View Megakaryocyte apoptosis in immune thrombocytopenia | Researchers | Basic research |
A platelet viability assay (PVA) for the diagnosis of heparin-induced thrombocytopenia | Ivetic N, Arnold D, Smith J, Huynh A, Kelton J, Nazy I | 2019 | Platelets | View A platelet viability assay (PVA) for the diagnosis of heparin-induced thrombocytopenia | Researchers | Basic research |
Microparticle and mitochondrial release during extended storage of different types of platelet concentrates | Marcoux G, Duchez A-C, Rousseau M, Levesque T, Boudreau LH, Thibault L, Boilard E | 2016 | Platelets | View Microparticle and mitochondrial release during extended storage of different types of platelet concentrates | Researchers | Basic research |
Catastrophic antiphospholipid syndrome refractory to high-dose intravenous immunoglobulin responsive to therapeutic plasma exchange | James TE, Martin LJ, Warkentin TE, Crowther MA | 2020 | Platelets | View Catastrophic antiphospholipid syndrome refractory to high-dose intravenous immunoglobulin responsive to therapeutic plasma exchange | Health care providers | Clinical research |
Spontaneous HIT syndrome post-knee replacement surgery with delayed recovery of thrombocytopenia: a case report and literature review | Poudel DR, Ghimire S, Dhital R, Forman DA, Warkentin TE | 2017 | Platelets | View Spontaneous HIT syndrome post-knee replacement surgery with delayed recovery of thrombocytopenia: a case report and literature review | Health care providers | Clinical research |
Successful treatment with oseltamivir phosphate in a patient with chronic immune thrombocytopenia positive for anti-GPIb/IX autoantibody | Shao L, Wu Y, Zhou H, Qin P, Ni H, Peng J, Hou M | 2014 | Platelets | View Successful treatment with oseltamivir phosphate in a patient with chronic immune thrombocytopenia positive for anti-GPIb/IX autoantibody | Health care providers | Clinical research |
Development of antifouling and bactericidal coatings for platelet storage bags using dopamine chemistry | Hadjesfandiari N, Weinhart M, Kizhakkedathu JN, Haag R, Brooks DE | 2018 | Adv Healthc Mater | View Development of antifouling and bactericidal coatings for platelet storage bags using dopamine chemistry | Researchers | New or improved product or process |
Dicer cleavage by calpain determines platelet microRNA levels and function in diabetes | Elgheznawy A, Shi L, Hu J, Wittig I, Laban H, Pircher J, Mann A, Provost P, Randriamboavonjy V, Fleming I | 2015 | Circ Res | View Dicer cleavage by calpain determines platelet microRNA levels and function in diabetes | Researchers | Basic research |
Targeting activated platelets and fibrinolysis: hitting two birds with one stone | Reheman A, Xu X, Reddy EC, Ni H | 2014 | Circ Res | View Targeting activated platelets and fibrinolysis: hitting two birds with one stone | Researchers | Basic research |
Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion | Carson JL, Stanworth SJ, Roubinian N, Fergusson DA, Triulzi D, Doree C, Hebert PC | 2016 | Cochrane Database Syst Rev | View Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion | Health care providers | Clinical research |
Restrictive versus liberal red blood cell transfusion strategies for people with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem cell support | Estcourt LJ, Malouf R, Trivella M, Fergusson DA, Hopewell S, Murphy MF | 2017 | Cochrane Database Syst Rev | View Restrictive versus liberal red blood cell transfusion strategies for people with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem cell support | Health care providers | Clinical research |
Different doses of prophylactic platelet transfusion for preventing bleeding in patients with haematological disorders after chemotherapy or stem cell transplantation (Protocol) | Estcourt LJ, Stanworth S, Doree C, Trivella M, Hopewell S, Murphy MF, Tinmouth A | 2014 | Cochrane Database Syst Rev | View Different doses of prophylactic platelet transfusion for preventing bleeding in patients with haematological disorders after chemotherapy or stem cell transplantation (Protocol) | Researchers | Clinical research |
Clotting factor concentrates for preventing bleeding and bleeding-related complications in previously treated individuals with haemophilia A or B | Olasupo OO, Lowe MS, Krishan A, Collins P, Iorio A, Matino D | 2021 | Cochrane Database Syst Rev | View Clotting factor concentrates for preventing bleeding and bleeding-related complications in previously treated individuals with haemophilia A or B | Health care providers | Clinical research |
Disulfide linked pyrazole derivatives inhibit phagocytosis of opsonized blood cells | Purohit MK, Scovell I, Neschadim A, Katsman Y, Branch DR, Kotra LP | 2013 | Bioorg Med Chem Lett | View Disulfide linked pyrazole derivatives inhibit phagocytosis of opsonized blood cells | Researchers | Basic research |
COVID-19: Blood centres rise to the occasion and lead seroprevalence studies | Lieshout-Krikke RW, O'Brien SF, Saeed S, Lewin A | 2020 | Transfusion Today | Health care providers | Clinical research | |
Canada's MSM Research Program - producing and mobilizing knowledge | Chargé S, Haw J | 2020 | Transfusion Today | Researchers | MSM research | |
Do we know if we deplete or treat the donor's iron? | Goldman M, Van den Burg P | 2017 | Transfusion Today | View Do we know if we deplete or treat the donor's iron? | Health care providers | Clinical research |
Red blood cell transfusion and mortality effect in aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis protocol | English SW, Chassé M, Turgeon AF, Tinmouth A, Boutin A, Pagliarello G, Fergusson D, McIntyre L | 2015 | Syst Rev | View Red blood cell transfusion and mortality effect in aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis protocol | Researchers | Clinical research |
Red blood cell transfusion in patients with traumatic brain injury: a systematic review protocol | Boutin A, Chasse M, Shemilt M, Lauzier F, Moore L, Zarychanski R, Lacroix J, Fergusson DA, Desjardins P, Turgeon AF | 2014 | Syst Rev | View Red blood cell transfusion in patients with traumatic brain injury: a systematic review protocol | Researchers | Other |
Effect of blood donor characteristics on transfusion outcomes: a protocol for systematic review and meta-analysis | Chasse M, English S, McIntyre L, Knoll G, Shehata N, Forster A, Wilson K, van Walraven C, Tinmouth A, Fergusson D | 2014 | Syst Rev | View Effect of blood donor characteristics on transfusion outcomes: a protocol for systematic review and meta-analysis | Researchers | Clinical research |
Efficacy and safety of mesenchymal stromal cells in preclinical models of acute lung injury: a systematic review protocol | Lalu MM, Moher D, Marshall J, Fergusson D, Mei SH, Macleod M, Griffin G, Turgeon AF, Rudnicki M, Fishman J, Avey MT, Skidmore B, Grimshaw JM, Stewart DJ, Singh K, McIntyre L | 2014 | Syst Rev | View Efficacy and safety of mesenchymal stromal cells in preclinical models of acute lung injury: a systematic review protocol | Researchers | Clinical research |
Efficacy and safety of regenerative cell therapy for pulmonary arterial hypertension in animal models: a preclinical systematic review protocol | Suen CM, Zhai A, Lalu MM, Welsh C, Levac BM, Fergusson D, McIntyre L, Stewart DJ | 2016 | Syst Rev | View Efficacy and safety of regenerative cell therapy for pulmonary arterial hypertension in animal models: a preclinical systematic review protocol | Researchers | Basic research |
Vitamin D and kidney transplant outcomes: a protocol for a systematic review and meta-analysis | Hesketh CC, Knoll GA, Molnar AO, Tsampalieros A, Zimmerman DL | 2014 | Syst Rev | View Vitamin D and kidney transplant outcomes: a protocol for a systematic review and meta-analysis | Researchers | Clinical research |
Does intravenous contrast-enhanced computed tomography cause acute kidney injury? Protocol of a systematic review of the evidence | Kayibanda JF, Hiremath S, Knoll GA, Fergusson D, Chow BJ, Shabana W, Akbari A | 2014 | Syst Rev | View Does intravenous contrast-enhanced computed tomography cause acute kidney injury? Protocol of a systematic review of the evidence | Researchers | Clinical research |
Does treatment order matter? Investigating the ability of bacteriophage to augment antibiotic activity against Staphylococcus aureus biofilms | Kumaran D, Taha M, Yi Q, Ramirez-Arcos S, Diallo JS, Carli A, Abdelbary H | 2018 | Front Microbiol | View Does treatment order matter? Investigating the ability of bacteriophage to augment antibiotic activity against Staphylococcus aureus biofilms | Researchers | Basic research |
In silico analysis suggests interaction between Ebola virus and the extracellular matrix | Veljkovic V, Glisic S, Muller CP, Scotch M, Branch DR, Perovic VR, Sencanski M, Veljkovic N, Colombatti A | 2015 | Front Microbiol | View In silico analysis suggests interaction between Ebola virus and the extracellular matrix | Researchers | Basic research |
Drugs in ITP: Mechanisms of Action | Crow AR, Lazarus AH | 2013 | Immune Thrombocytopenia (ITP) | View Drugs in ITP: Mechanisms of Action | Researchers | Other |
Eadie-Hofstee analysis of red blood cell deformability | Stadnick H, Onell R, Acker JP, Holovati JL | 2011 | Clin Hemorheol Microcirc | View Eadie-Hofstee analysis of red blood cell deformability | Researchers | Basic research |
Ebola virus VP35 blocks stress granule assembly | Le Sage V, Cinti A, McCarthy S, Amorim R, Rao S, Daino GL, Tramontano E, Branch DR, Mouland AJ | 2017 | Virology | View Ebola virus VP35 blocks stress granule assembly | Researchers | Basic research |
The immune-stimulation capacity of liposome-treated red blood cells | da Silveira Cavalcante L, Branch DR, Duong TT, Yeung RSM, Acker JP, Holovati JL | 2017 | J Liposome Res | View The immune-stimulation capacity of liposome-treated red blood cells | Researchers | Basic research |
Effect of liposome-treated red blood cells in an anemic rat model | da Silveira Cavalcante L, Feng Q, Chin-Yee I, Acker JP, Holovati JL | 2016 | J Liposome Res | View Effect of liposome-treated red blood cells in an anemic rat model | Researchers | Basic research |
Effect of sirolimus on malignancy and survival after kidney transplantation: systematic review and meta-analysis of individual patient data | Knoll GA, Kokolo MB, Mallick R, Beck A, Buenaventura CD, Ducharme R, Barsoum R, Bernasconi C, Blydt-Hansen TD, Ekberg H, Felipe CR, Firth J, Gallon L, Gelens M, Glotz D, Gossmann J, Guba M, Morsy AA, Salgo R, Scheuermann EH, Tedesco-Silva H, Vitko S, Watson C, Fergusson DA | 2014 | BMJ | View Effect of sirolimus on malignancy and survival after kidney transplantation: systematic review and meta-analysis of individual patient data | Health care providers | Clinical research |
Antibody and cellular therapies for treatment of covid-19: a living systematic review and network meta-analysis | Siemieniuk RA, Bartoszko JJ, Díaz Martinez JP, Kum E, Qasim A, Zeraatkar D, Izcovich A, Mangala S, Ge L, Han MA, Agoritsas T, Arnold D, Ávila C, Chu DK, Couban R, Cusano E, Darzi AJ, Devji T, Foroutan F, Ghadimi M, Khamis A, Lamontagne F, Loeb M, Miroshnychenko A, Motaghi S, Murthy S, Mustafa RA, Rada G, Rochwerg B, Switzer C, Vandvik PO, Vernooij RW, Wang Y, Yao L, Guyatt GH, Brignardello-Petersen R | 2021 | BMJ | View Antibody and cellular therapies for treatment of covid-19: a living systematic review and network meta-analysis | Researchers | Clinical research |
Generic immunosuppression in solid organ transplantation: systematic review and meta-analysis | Molnar AO, Fergusson D, Tsampalieros AK, Bennett A, Fergusson N, Ramsay T, Knoll GA | 2015 | BMJ | View Generic immunosuppression in solid organ transplantation: systematic review and meta-analysis | Health care providers | Clinical research |
Eltrombopag after allogeneic haematopoietic cell transplantation in a case of poor graft function and systematic review of the literature | Dyba J, Tinmouth A, Bredeson C, Matthews J, Allan DS | 2016 | Transfus Med | View Eltrombopag after allogeneic haematopoietic cell transplantation in a case of poor graft function and systematic review of the literature | Researchers | Clinical research |
Encapsulation of factor IX-engineered mesenchymal stem cells in fibrinogen-alginate microcapsules enhances their viability and transgene secretion | Sayyar B, Dodd M, Wen J, Ma S, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G | 2012 | J Tissue Eng | View Encapsulation of factor IX-engineered mesenchymal stem cells in fibrinogen-alginate microcapsules enhances their viability and transgene secretion | Researchers | Basic research |
Endothelial-Specific Deletion of Autophagy Related 7 (ATG7) Attenuates Arterial Thrombosis in Mice | Yau JW, Singh KK, Hou Y, Lei X, Ramadan A, Quan A, Teoh H, Kuebler WM, Al-Omran M, Yanagawa B, Ni H, Verma S | 2017 | J Thorac Cardiovasc Surg | View Endothelial-Specific Deletion of Autophagy Related 7 (ATG7) Attenuates Arterial Thrombosis in Mice | Researchers | Basic research |
Engineering biomaterials surfaces to modulate the host response | Yu K, Mei Y, Hadjesfandiari N, Kizhakkedathu JN | 2014 | Colloids Surf B Biointerfaces | View Engineering biomaterials surfaces to modulate the host response | Researchers | Basic research |
Enhanced Cell Surface Polymer Grafting in Concentrated and Nonreactive Aqueous Polymer Solutions | Rossi NAA, Constantinescu I, Brooks DE, Scott MD, Kizhakkedathu JN | 2010 | J Am Chem Soc | View Enhanced Cell Surface Polymer Grafting in Concentrated and Nonreactive Aqueous Polymer Solutions | Researchers | Basic research |
Toward Efficient Enzymes for the Generation of Universal Blood through Structure-Guided Directed Evolution | Kwan DH, Constantinescu I, Chapanian R, Higgins MA, Kotzler MP, Samain E, Boraston AB, Kizhakkedathu JN, Withers SG | 2015 | J Am Chem Soc | View Toward Efficient Enzymes for the Generation of Universal Blood through Structure-Guided Directed Evolution | Researchers | New or improved product or process |
Increasing efficiency in protein-protein coupling: subunit-directed acetylation and phase-directed CuAAC ("click coupling") in the formation of hemoglobin bis-tetramers | Wang A, Kluger R | 2014 | Biochemistry | View Increasing efficiency in protein-protein coupling: subunit-directed acetylation and phase-directed CuAAC ("click coupling") in the formation of hemoglobin bis-tetramers | Researchers | Basic research |
Enhanced Nitrite Reductase Activity and Its Correlation with Oxygen Affinity in Hemoglobin Bis-Tetramers | Wang A, Kluger R | 2016 | Biochemistry | View Enhanced Nitrite Reductase Activity and Its Correlation with Oxygen Affinity in Hemoglobin Bis-Tetramers | Researchers | Basic research |
Self-Assembly of a Functional Triple Protein: Hemoglobin-Avidin-Hemoglobin via Biotin–Avidin Interactions | Singh S, Kluger R | 2016 | Biochemistry | View Self-Assembly of a Functional Triple Protein: Hemoglobin-Avidin-Hemoglobin via Biotin–Avidin Interactions | Researchers | Basic research |
Enhancing the Migration Ability of Mesenchymal Stromal Cells by Targeting the SDF-1/CXCR4 Axis | Marquez-Curtis LA, Janowska-Wieczorek A | 2013 | BioMed Res Int | View Enhancing the Migration Ability of Mesenchymal Stromal Cells by Targeting the SDF-1/CXCR4 Axis | Researchers | Basic research |
Epigenetic regulation of endothelial-cell-mediated vascular repair | Fraineau S, Palii CG, Allan DS, Brand M | 2015 | FEBS J | View Epigenetic regulation of endothelial-cell-mediated vascular repair | Researchers | Other |
Impact of technical and assay variation on reporting of hemolysis in stored red blood cell products | Almizraq RJ, Yi QL, Acker JP | 2017 | Clinica Chimica Acta | View Impact of technical and assay variation on reporting of hemolysis in stored red blood cell products | Blood operators | New or improved product or process |
Erroneous HbA1c results in a patient with elevated HbC and HbF | Adekanmbi J, Higgins T, Rodriguez-Capote K, Thomas D, Winterstein J, Dixon T, Gifford JL, Krause R, Venner AA, Clarke G, Estey MP | 2016 | Clinica Chimica Acta | View Erroneous HbA1c results in a patient with elevated HbC and HbF | Health care providers | Clinical research |
The recipe for TACO: A narrative review on the pathophysiology and potential mitigation strategies of transfusion-associated circulatory overload | Bulle EB, Klanderman RB, Pendergrast J, Cserti-Gazdewich C, Callum J, Vlaar APJ | 2022 | Blood Rev | View The recipe for TACO: A narrative review on the pathophysiology and potential mitigation strategies of transfusion-associated circulatory overload | Health care providers | Clinical research |
Eryptosis in health and disease: A paradigm shift towards understanding the (patho)physiological implications of programmed cell death of erythrocytes | Qadri SM, Bissinger R, Solh Z, Oldenborg PA | 2017 | Blood Rev | View Eryptosis in health and disease: A paradigm shift towards understanding the (patho)physiological implications of programmed cell death of erythrocytes | Researchers | Basic research |
Evaluating Health Care Policy Decisions: Canadian Blood Services in Atlantic Canada | Blake JT, Rogerson M, Harris D | 2013 | Operations Research and Health Care Policy | View Evaluating Health Care Policy Decisions: Canadian Blood Services in Atlantic Canada | Other | New or improved product or process |