Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Transfusion of fresher vs older red blood cells in hospitalized patients: a systematic review and meta-analysis Alexander PE, Barty R, Fei Y, Vandvik PO, Pai M, Siemieniuk RA, Heddle NM, Blumberg N, McLeod SL, Liu J, Eikelboom JW, Guyatt GH 2016 Blood View Researchers Clinical research
ResearchUnit: A different way to look at red blood cell quality Acker J 2018 Blood.ca website View Researchers Clinical research
Characterization of platelet factor 4 amino acids that bind pathogenic antibodies in heparin-induced thrombocytopenia Huynh A, Arnold DM, Kelton JG, Smith JW, Horsewood P, Clare R, Guarné A, Nazy I 2018 J Thromb Haemost View Researchers Basic research
IVIg and LPS Co-stimulation Induces IL-10 Production by Human Monocytes, Which Is Compromised by an FcgRIIA Disease-Associated Gene Variant Kozicky LK, Menzies SC, Zhao ZY, Vira T, Harnden K, Safari K, Del Bel KL, Turvey SE, Sly LM 2018 Front Immunol View Researchers Basic research
What's in a name? Patient registration errors and their threat to transfusion safety Ning S, Yan MTS, Downie H, Callum J 2018 Transfusion View Researchers New or improved product or process
Raman spectroscopy of stored red blood cell concentrate within sealed transfusion blood bags Vardaki MZ, Atkins CG, Schulze HG, Devine DV, Serrano K, Blades MW, Turner RFB 2018 Analyst View Researchers New or improved product or process
Defocused Spatially Offset Raman Spectroscopy in Media of Different Optical Properties for Biomedical Applications Using a Commercial Spatially Offset Raman Spectroscopy Device Vardaki MZ, Devine DV, Serrano K, Simantiris N, Blades MW, Piret JM, Turner RFB 2020 Appl Spectrosc View Researchers New or improved product or process
IgG3 anti-Kell allotypic variation results in differential antigen binding and phagocytosis Cen SY, Holton MB, Binnington B, Denomme GA, Howie HL, Lebedev JN, Zimring JC, Branch DR 2020 Transfusion View Researchers Basic research
Not all red cell concentrate units are equivalent: international survey of processing and in vitro quality data Shih AW, Apelseth TO, Cardigan R, Marks DC, Bégué S, Greinacher A, de Korte D, Seltsam A, Shaz BH, Wikman A, Barty RL, Heddle NM, Acker JP, The QMiP Investigators on behalf of the Biomedical Excellence for Safer Transfusion Collaborative 2019 Vox Sang View Researchers Benchmarking and standard setting
Canada's MSM Research Program - producing and mobilizing knowledge Chargé S, Haw J 2020 Transfusion Today Researchers MSM research
Emerging use of machine learning and advanced technologies to assess red cell quality Sebastian JA, Kolios MC, Acker JP 2020 Transfus Apher Sci View Researchers New or improved product or process
Objective assessment of stored blood quality by deep learning Doan M, Sebastian JA, Caicedo JC, Siegert S, Roch A, Turner TR, Mykhailova O, Pinto RN, McQuin C, Goodman A, Parsons MJ, Wolkenhauer O, Hennig H, Singh S, Wilson A, Acker JP, Rees P, Kolios MC, Carpenter AE 2020 PLoS Pathog View Researchers New or improved product or process
Research Unit: Machine learning throws away the buckets to better understand red blood cell quality Acker JP 2020 Blood.ca website View Researchers Basic research
Transfusion septic reactions involving platelet concentrates contaminated with Citrobacter koseri Ramirez-Arcos S 2020 Ann Blood View Researchers Clinical research
High sub-zero organ preservation: A paradigm of nature-inspired strategies William N, Acker JP 2021 Cryobiology View Researchers Basic research
Complete Genome Sequence of Staphylococcus aureus PS/BAC/169/17/W, Isolated from a Contaminated Platelet Concentrate in England Paredes C, Chi SI, Flint A, Weedmark K, McDonald C, Bearne J, Ramirez-Arcos S, Pagotto F, Baltrus DA 2021 Microbiol Resour Announc View Researchers Benchmarking and standard setting
Double high-dose immunoglobulin for ChAdOx1 nCov-19 vaccine-induced immune thrombotic thrombocytopenia Huang CT, Hsu SY, Wang CH, Tseng WJ, Yang CY, Ng CJ, Warkentin TE, Cheng MH 2021 Thromb Res View Researchers Clinical research
Cost-effectiveness of noninvasive fetal RhD blood group genotyping in nonalloimmunized and alloimmunized pregnancies Gajic-Veljanoski O, Li C, Schaink AK, Guo J, Shehata N, Charames GS, de Vrijer B, Clarke G, Pechlivanoglou P, Okun N, Kandel R, Dooley J, Higgins C, Ng V, Sikich N 2022 Transfusion View Researchers Clinical research
The Relationship Between Anti-Spike SARS-CoV-2 Antibody Levels and Risk of Breakthrough COVID-19 Among Fully Vaccinated Adults Asamoah-Boaheng M, Goldfarb DM, Karim ME, O’Brien SF, Wall N, Drews SJ, Barakauskas V, Jassem AN, Grunau B 2022 J Infect Dis View Researchers Clinical research
Assessment of the soluble proteins HMGB1, CD40L and CD62P during various platelet preparation processes and the storage of platelet concentrates: The BEST collaborative study Cognasse F, Hamzeh Cognasse H, Eyraud MA, Prier A, Arthaud CA, Tiberghien P, Begue S, de Korte D, Gouwerok E, Greinacher A, Aurich K, Noorman F, Dumont L, Kelly K, Cloutier M, Bazin R, Cardigan R, Huish S, Smethurst P, Devine D, Schubert P, Johnson L, Marks DC, Biomedical Excellence for Safer Transfusion Collaborative 2023 Transfusion View Researchers Basic research
HIV incidence and related risks among gay, bisexual, and other men who have sex with men in Montreal, Toronto, and Vancouver: Informing blood donor selection criteria in Canada Lambert G, Cox J, Fourmigue A, Dvorakova M, Apelian H, Moodie EEM, Grace D, Skakoon-Sparling S, Moore DM, Lachowsky N, Jollimore J, Lal A, Parlette A, Hart TA 2022 Transfusion View Researchers MSM research
Multicenter evaluation of the IL-3-pSTAT5 assay to assess the potency of cryopreserved stem cells from cord blood units: The BEST Collaborative study Trépanier P, Fournier D, Simard C, Fontaine MJ, Stroncek D, Takanashi M, McKenna D, Schwartz J, Tanhehco YC, Reems J-A, Torrents S, Kogler G, Liedtke S, Giroux M, Holovati JL, Louis I, Prasath A, Pineault N, Bazin R, The Biomedical Excellence for Safer Transfusion Collaborative 2022 Transfusion View Researchers Benchmarking and standard setting
A lab-on-chip for malaria diagnosis and surveillance Taylor BJ, Howell A, Martin KA, Manage DP, Gordy W, Campbell SD, Lam S, Jin A, Polley SD, Samuel RA, Atrazhev A, Stickel AJ, Birungi J, Mbonye AK, Pilarski LM, Acker JP, Yanow SK 2014 Malar J View Researchers Basic research
Applications of Liposomes in Biopreservation Da Silveira Cavalcante L, Holovati J, Acker J 2016 Multiscale technologies for cryomedicine: implementation from nano to macroscale View Researchers Basic research
Biomonitoring of Arsenic in Urine and Saliva of Children Playing on Playgrounds Constructed from Chromated Copper Arsenate-Treated Wood Lew K, Acker JP, Gabos S, Le XC 2010 Environ Sci Technol View Researchers Other
Carbohydrate-based ice recrystallization inhibitors increase infectivity and thermostability of viral vectors Ghobadloo SM, Balcerzak AK, Gargaun A, Muharemagic D, Mironov GG, Capicciotti CJ, Briard JG, Ben RN, Berezovski MV 2014 Sci Rep View Researchers Basic research
Emerging Role for Use of Liposomes in the Biopreservation of Red Blood Cells Holovati JL, Acker JP 2011 Transfus Med Hemother View Researchers Basic research
Fibronectin: extra domain brings extra risk? Wang Y, Ni H 2015 Blood View Researchers Other
Immunocamouflage of latex surfaces by grafted methoxypoly(ethylene glycol) (mPEG): proteomic analysis of plasma protein adsorption Le Y, Li L, Wang D, Scott MD 2012 Sci China Life Sci View Researchers Basic research
Incorporation of albumin fusion proteins into fibrin clots in vitro and in vivo: comparison of different fusion motifs recognized by factor XIIIa Sheffield WP, Eltringham-Smith LJ 2011 BMC Biotechnol View Researchers Basic research
Manufacturing method affects mitochondrial DNA release and extracellular vesicle composition in stored red blood cells Bakkour S, Acker JP, Chafets DM, Inglis HC, Norris PJ, Lee TH, Busch MP 2016 Vox Sang View Researchers Basic research
Mitochondria and membrane cryoinjury in micropatterned cells: Effects of cell-cell interactions Tchir J, Acker JP 2010 Cryobiology View Researchers Basic research
Platelet immunology in China: research and clinical applications Wu G, Zhou Y, Li L, Zhong Z, Li H, Li H, Yu M, Shen W, Ni H 2017 Transfus Med Rev View Researchers Clinical research
Renin-Angiotensin System Blockade and Long-term Clinical Outcomes in Kidney Transplant Recipients: A Meta-analysis of Randomized Controlled Trials Hiremath S, Fergusson DA, Fergusson N, Bennett A, Knoll GA 2017 Am J Kidney Dis View Researchers Clinical research
Solving the dilemma of prevention of red cell alloimmunization Branch DR 2012 Immunotherapy View Researchers Other
The cell motility modulator Slit2 is a potent inhibitor of platelet function Patel S, Huang YW, Reheman A, Pluthero FG, Chaturvedi S, Mukovozov IM, Tole S, Liu GY, Li L, Durocher Y, Ni H, Kahr WH, Robinson LA 2012 Circulation View Researchers Basic research
Therapeutic Effect of IVIG on Inflammatory Arthritis in Mice Is Dependent on the Fc Portion and Independent of Sialylation or Basophils Campbell IK, Miescher S, Branch DR, Mott PJ, Lazarus AH, Han D, Maraskovsky E, Zuercher AW, Neschadim A, Leontyev D, McKenzie BS, Kasermann F 2014 J Immunol View Researchers Basic research
Vascular endothelial dysfunction in beta-thalassemia occurs despite increased eNOS expression and preserved vascular smooth muscle cell reactivity to NO Stoyanova E, Trudel M, Felfly H, Lemsaddek W, Garcia D, Cloutier G 2012 PLoS One View Researchers Basic research
Modelling the Need for New Blood Donors Following a Change in Deferral Period Blake J 2018 Industrial Engineering and Operations Management I View Researchers Clinical research
Assessing opportunities and challenges for establishing a national program to distribute cord blood for research Isasi R, Mastronardi C, Golder M, Allan D, Walker M, Halpenny M, Yang L, Elmoazzen H, Chargé S 2018 Transfusion View Researchers Other
GM-CSF and IL-4 are not involved in IVIG-mediated amelioration of ITP in mice: a role for IL-11 cannot be ruled out Lewis BJB, Leontyev D, Neschadim A, Blacquiere M, Branch DR 2018 Clin Exp Immunol View Researchers Basic research
ResearchUnit: Plasma: what's in the bag? Sheffield W, Jenkins C 2018 Blood.ca website View Researchers Basic research
Engineering the serpin alpha 1-antitrypsin: A diversity of goals and techniques Scott BM, Sheffield WP 2020 Protein Sci View Researchers Basic research
Ironing out frequent blood donation Devine DV 2019 Lancet Haematol View Researchers New or improved product or process
Platelet vesicles are potent inflammatory mediators in red blood cell products and washing reduces the inflammatory phenotype Almizraq R, Kipkeu B, Acker JP 2020 Transfusion View Researchers Basic research
An AI-Driven Predictive Modelling Framework to Analyze and Visualize Blood Product Transactional Data for Reducing Blood Products’ Discards Rad J, Cheng C, Quinn JG, Abidi S, Liwski R, Abidi SSR 2020 Artificial Intelligence in Medicine View Researchers New or improved product or process
Cryoprotectant-dependent control of intracellular ice recrystallization in hepatocytes using small molecule carbohydrate derivatives William N, Acker JP 2020 Cryobiology View Researchers Basic research
Exploring the components of bleeding outcomes in transfusion trials for patients with hematologic malignancy Balitsky AK, Liu Y, Van der Meer PF, Heddle NM, Arnold DM 2021 Transfusion View Researchers Clinical research
SARS-CoV-2 seroprevalence among blood donors after the first COVID-19 wave in Canada Saeed S, Drews SJ, Pambrun C, Yi Q-L, Osmond L, O'Brien SF 2021 Transfusion View Researchers Clinical research
Updated Understanding of Platelets in Thrombosis and Hemostasis: The Roles of Integrin PSI Domains and their Potential as Therapeutic Targets MacKeigan DT, Ni T, Shen C, Stratton TW, Ma W, Zhu G, Bhoria P, Ni H 2020 Cardiovasc Hematol Disord Drug Targets View Researchers Basic research