Our Research Publications
Updated November 2023
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Title | Authors | Year | Journal Sort ascending | Link to Article | Intended Audience | Purpose |
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Cost-effectiveness of Fibrinogen Concentrate vs Cryoprecipitate for Treating Acquired Hypofibrinogenemia in Bleeding Adult Cardiac Surgical Patients | Abrahamyan L, Tomlinson G, Callum J, Carcone S, Grewal D, Bartoszko J, Krahn M, Karkouti K | 2023 | JAMA Surg | View Cost-effectiveness of Fibrinogen Concentrate vs Cryoprecipitate for Treating Acquired Hypofibrinogenemia in Bleeding Adult Cardiac Surgical Patients | Health care providers | Clinical research |
Ketamine administration for acute painful sickle cell crisis: A randomized controlled trial | Alshahrani MS, AlSulaibikh AH, ElTahan MR, AlFaraj SZ, Asonto LP, AlMulhim AA, AlAbbad MF, Almaghraby N, AlJumaan MA, AlJunaid TO, Darweesh MN, AlHawaj FM, Mahmoud AM, Alossaimi BK, Alotaibi SK, AlMutairi TM, AlSulaiman Pharm DD, Alfaraj D, Alhawwas R, Mbuagbaw L, Lewis K, Verhovsek M, Crowther M, Guyatt G, Alhazzani W | 2021 | Acad Emerg Med | View Ketamine administration for acute painful sickle cell crisis: A randomized controlled trial | Researchers | Clinical research |
The Effect of Sex-Mismatched Red Blood Cell Transfusion on Endothelial Cell Activation in Critically Ill Patients | Alshalani A, van Manen L, Boshuizen M, van Bruggen R, Acker JP, Juffermans NP | 2021 | Transfus Med Hemotherapy | View The Effect of Sex-Mismatched Red Blood Cell Transfusion on Endothelial Cell Activation in Critically Ill Patients | Researchers | Clinical research |
In Vitro Effect of Methamphetamine on Proliferation, Differentiation and Apoptosis of Adipose Tissue Stem Cells: In vitro Effect of Methamphetamine | Anari L, Mehrabani D, Nasiri M, Zare S, Jamhiri I, Acker J | 2022 | J Pharm Sci | View In Vitro Effect of Methamphetamine on Proliferation, Differentiation and Apoptosis of Adipose Tissue Stem Cells: In vitro Effect of Methamphetamine | Researchers | Basic research |
Epidemiology of Hospitalized Patients with Babesiosis, United States, 2010-2016 | Bloch EM, Day JR, Krause PJ, Kjemtrup A, O'Brien SF, Tobian AAR, Goel R | 2022 | Emerg Infect Dis | View Epidemiology of Hospitalized Patients with Babesiosis, United States, 2010-2016 | Health care providers | Clinical research |
Newer formulations of intravenous iron: a review of their chemistry and key safety aspects – hypersensitivity, hypophosphatemia, and cardiovascular safety | Blumenstein I, Shanbhag S, Langguth P, Kalra PA, Zoller H, Lim W | 2021 | Expert Opin Drug Saf | View Newer formulations of intravenous iron: a review of their chemistry and key safety aspects – hypersensitivity, hypophosphatemia, and cardiovascular safety | Researchers | Basic research |
Discrete-Event Simulation to Model the Thrombolysis Process for Acute Ischemic Stroke Patients at Urban and Rural Hospitals | Bulmer T, Volders D, Blake J, Kamal N | 2021 | Front Neurol | View Discrete-Event Simulation to Model the Thrombolysis Process for Acute Ischemic Stroke Patients at Urban and Rural Hospitals | Researchers | New or improved product or process |
Chapter 4: Clinical transfusion procedures | Clarke G, Al-Riyami AZ, Roxby D | 2021 | Educational Modules on Clinical Use of Blood | View Chapter 4: Clinical transfusion procedures | Health care providers | Benchmarking and standard setting |
A scalable serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccination | Colwill K, Galipeau Y, Stuible M, Gervais C, Arnold C, Rathod B, Abe KT, Wang JH, Pasculescu A, Maltseva M, Rocheleau L, Pelchat M, Fazel-Zarandi M, Iskilova M, Barrios-Rodiles M, Bennett L, Yau K, Cholette F, Mesa C, Li AX, Paterson A, Hladunewich MA, Goodwin PJ, Wrana JL, Drews SJ, Mubareka S, McGeer AJ, Kim J, Langlois M-A, Gingras A-C, Durocher Y | 2022 | Clin Transl Immunol | View A scalable serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccination | Researchers | New or improved product or process |
Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score | COVIDSurg Collaborative | 2021 | Br J Surg | View Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score | Health care providers | Benchmarking and standard setting |
Using Blood Wisely One Year Later – Ontario Hospitals Stepping Up to the Challenge | Day D, Lin Y | 2021 | Ontario Regional Blood Coordinating Network September 2021 Newsletter | View Using Blood Wisely One Year Later – Ontario Hospitals Stepping Up to the Challenge | Health care providers | Benchmarking and standard setting |
User-Centered Development and Testing of the Online Patient-Reported Outcomes, Burdens, and Experiences (PROBE) Survey and the myPROBE App and Integration With the Canadian Bleeding Disorder Registry: Mixed Methods Study | Germini F, Borg Debono V, Page D, Zuk V, Kucher A, Cotoi C, Hobson N, Sevestre M, Skinner MW, Iorio A | 2022 | JMIR Hum Factors | View User-Centered Development and Testing of the Online Patient-Reported Outcomes, Burdens, and Experiences (PROBE) Survey and the myPROBE App and Integration With the Canadian Bleeding Disorder Registry: Mixed Methods Study | Researchers | Benchmarking and standard setting |
Maintaining trust in a pandemic: Blood collection agency messaging to donors and the public during the early days of COVID-19 | Haw J, Thorpe R, Holloway K | 2021 | SocArXiv | View Maintaining trust in a pandemic: Blood collection agency messaging to donors and the public during the early days of COVID-19 | Blood operators | Ethical, legal and social implications research |
Blood Collection Agency Messaging to Donors and the Public in Canada and Australia During the Early Days of COVID-19 | Haw J, Thorpe R, Holloway K | 2022 | Front Commun | View Blood Collection Agency Messaging to Donors and the Public in Canada and Australia During the Early Days of COVID-19 | Blood operators | Ethical, legal and social implications research |
Teaching bone marrow procedures at pelvic and sternal sites: a high fidelity anatomy simulation | Heather Vander M, Laureano M, Hu G, Lim W, Ross C, Wainman B, Zeller MP | 2021 | Can Med Educ J | View Teaching bone marrow procedures at pelvic and sternal sites: a high fidelity anatomy simulation | Health care providers | Benchmarking and standard setting |
The Market in Noninvasive Prenatal Tests and the Message to Consumers: Exploring Responsibility | Holloway K, Simms N, Hayeems RZ, Miller FA | 2022 | Hastings Cent Rep | View The Market in Noninvasive Prenatal Tests and the Message to Consumers: Exploring Responsibility | Regulators | Ethical, legal and social implications research |
Exploring the reasons for low pertussis vaccine effectiveness in Ontario, Canada, 2006–2008: a Canadian Immunization Research Network study | Hughes SL, Kwong JC, Schwartz KL, Chen C, Johnson C, Li Y, Marchand-Austin A, Bolotin S, Jamieson FB, Drews SJ, Russell ML, Svenson LW, Mahmud SM, Crowcroft NS | 2022 | Can J Public Health | View Exploring the reasons for low pertussis vaccine effectiveness in Ontario, Canada, 2006–2008: a Canadian Immunization Research Network study | Regulators | Clinical research |
Hepatitis B Blood Donor Screening Data: An Under-Recognized Resource for Canadian Public Health Surveillance | O’Brien SF, Reedman CN, Osiowy C, Bolotin S, Yi Q-L, Lourenço L, Lewin A, Binka M, Caffrey N, Drews SJ | 2023 | Viruses | View Hepatitis B Blood Donor Screening Data: An Under-Recognized Resource for Canadian Public Health Surveillance | Researchers | Clinical research |
Characteristics of Anti-SARS-CoV-2 Antibodies in Recovered COVID-19 Subjects | Huynh A, Arnold DM, Smith JW, Moore JC, Zhang A, Chagla Z, Harvey BJ, Stacey HD, Ang JC, Clare R, Ivetic N, Chetty VT, Bowdish DME, Miller MS, Kelton JG, Nazy I | 2021 | Viruses | View Characteristics of Anti-SARS-CoV-2 Antibodies in Recovered COVID-19 Subjects | Researchers | Clinical research |
Lessons Learned from the COVID-19 Pandemic and How Blood Operators Can Prepare for the Next Pandemic | Drews SJ, O’Brien SF | 2022 | Viruses | View Lessons Learned from the COVID-19 Pandemic and How Blood Operators Can Prepare for the Next Pandemic | Blood operators | New or improved product or process |
SARS-CoV-2 Seroprevalence among Canadian Blood Donors: The Advance of Omicron | O’Brien SF, Caffrey N, Yi Q-L, Pambrun C, Drews SJ | 2022 | Viruses | View SARS-CoV-2 Seroprevalence among Canadian Blood Donors: The Advance of Omicron | Researchers | Clinical research |
Antibody epitopes in vaccine-induced immune thrombotic thrombocytopaenia | Huynh A, Kelton JG, Arnold DM, Daka M, Nazy I | 2021 | Nature | View Antibody epitopes in vaccine-induced immune thrombotic thrombocytopaenia | Researchers | Clinical research |
Examining prescribing practices with respect to oral iron supplementation for post-partum anemia: a retrospective review | Iancu AM, Buckstein J, Melamed N, Lin Y | 2021 | J Matern Fetal Neonatal Med | View Examining prescribing practices with respect to oral iron supplementation for post-partum anemia: a retrospective review | Health care providers | Clinical research |
Plateletworks® as a Point-of-Care Test for ASA Non-Sensitivity | Khan H, Jain S, Gallant RC, Syed MH, Zamzam A, Al-Omran M, Rand ML, Ni H, Abdin R, Qadura M | 2021 | J Pers Med | View Plateletworks® as a Point-of-Care Test for ASA Non-Sensitivity | Researchers | New or improved product or process |
Improving Medical Education in Hematology and Transfusion Medicine in Canada: Standards and Limitations | Laureano M, Mithoowani S, Tseng E, Zeller M | 2021 | Adv Med Educ Pract | View Improving Medical Education in Hematology and Transfusion Medicine in Canada: Standards and Limitations | Health care providers | Benchmarking and standard setting |
Persistently elevated complement alternative pathway biomarkers in COVID-19 correlate with hypoxemia and predict in-hospital mortality | Leatherdale A, Stukas S, Lei V, West HE, Campbell CJ, Hoiland RL, Cooper J, Wellington CL, Sekhon MS, Pryzdial ELG, Conway EM | 2022 | Med Microbiol Immunol | View Persistently elevated complement alternative pathway biomarkers in COVID-19 correlate with hypoxemia and predict in-hospital mortality | Health care providers | Clinical research |
Response to ‘Adverse cardiac outcomes in patients with chronic myeloid leukaemia treated with tyrosine kinase inhibitors’ | Leong D, Hillis C, Aghel N, Pond G, Seow H | 2021 | Heart | View Response to ‘Adverse cardiac outcomes in patients with chronic myeloid leukaemia treated with tyrosine kinase inhibitors’ | Researchers | Clinical research |
Small Molecule Drugs That Inhibit Phagocytosis | Loriamini M, Lewis-Bakker MM, Frias Boligan K, Wang S, Holton MB, Kotra LP, Branch DR | 2023 | Molecules | View Small Molecule Drugs That Inhibit Phagocytosis | Researchers | Basic research |
Soy Isoflavones Inhibit Both GPIb-IX Signaling and ?IIb?3 Outside-In Signaling via 14-3-3? in Platelet | Liu M, Wang G, Xu R, Shen C, Ni H, Lai R | 2021 | Molecules | View Soy Isoflavones Inhibit Both GPIb-IX Signaling and ?IIb?3 Outside-In Signaling via 14-3-3? in Platelet | Researchers | Basic research |
Major clinical trial finds convalescent plasma does not help patients with COVID-19 | Modi D | 2021 | Ontario Regional Blood Coordinating Network December 2021 Newsletter | View Major clinical trial finds convalescent plasma does not help patients with COVID-19 | Health care providers | Clinical research |
The estimated risk of SARS-CoV- 2 infection via cornea transplant in Canada | O’Brien SF, Lewin A, Yi Q-L, Dowling G, Fissette E, Drews SJ | 2021 | Cell Tissue Bank | View The estimated risk of SARS-CoV- 2 infection via cornea transplant in Canada | Health care providers | Clinical research |
Viper venoms drive the macrophages and hepatocytes to sequester and clear platelets: novel mechanism and therapeutic strategy for venom-induced thrombocytopenia | Shen C, Liu M, Mackeigan DT, Chen ZY, Chen P, Karakas D, Li J, Norris PAA, Li J, Deng Y, Long C, Lai R, Ni H | 2021 | Arch Toxicol | View Viper venoms drive the macrophages and hepatocytes to sequester and clear platelets: novel mechanism and therapeutic strategy for venom-induced thrombocytopenia | Researchers | Basic research |
Inductively-Coupled Plasma Mass Spectrometry-Novel Insights From an Old Technology Into Stressed Red Blood Cell Physiology | Stephenson D, Nemkov T, Qadri SM, Sheffield WP, D'Alessandro A | 2022 | Front Physiol | View Inductively-Coupled Plasma Mass Spectrometry-Novel Insights From an Old Technology Into Stressed Red Blood Cell Physiology | Researchers | Basic research |
The impact of biological age of red blood cell on in vitro endothelial activation markers | Alshalani A, Beuger BM, Tuip-de Boer AM, van Bruggen R, Acker JP, Juffermans NP | 2023 | Front Physiol | View The impact of biological age of red blood cell on in vitro endothelial activation markers | Researchers | Basic research |
Evaluating the Tactical Combat Casualty Care principles in civilian and military settings: systematic review, knowledge gap analysis and recommendations for future research | Strauss R, Menchetti I, Perrier L, Blondal E, Peng H, Sullivan-Kwantes W, Tien H, Nathens A, Beckett A, Callum J, da Luz LT | 2021 | Trauma Surg Acute Care Open | View Evaluating the Tactical Combat Casualty Care principles in civilian and military settings: systematic review, knowledge gap analysis and recommendations for future research | Health care providers | Clinical research |
Massive Hemorrhage Protocol: Quality Metrics Portal Pilot | Thompson T, Callum J | 2022 | Ontario Regional Blood Coordinating Network February 2022 Newsletter | View Massive Hemorrhage Protocol: Quality Metrics Portal Pilot | Health care providers | Clinical research |
Utilization of the Abbott SARS-CoV-2 IgG II Quant Assay To Identify High-Titer Anti-SARS-CoV-2 Neutralizing Plasma against Wild-Type and Variant SARS-CoV-2 Viruses | Lin Y-CJ, Evans DH, Robbins NF, Orjuela G, Hu Q, Samson R, Abe KT, Rathod B, Colwill K, Gingras A-C, Tuite A, Yi Q-L, O’Brien SF, Drews SJ | 2022 | Microbiol Spectr | View Utilization of the Abbott SARS-CoV-2 IgG II Quant Assay To Identify High-Titer Anti-SARS-CoV-2 Neutralizing Plasma against Wild-Type and Variant SARS-CoV-2 Viruses | Health care providers | Benchmarking and standard setting |
Correlation of SARS-CoV-2 Viral Neutralizing Antibody Titers with Anti-Spike Antibodies and ACE-2 Inhibition among Vaccinated Individuals | Grunau B, Prusinkiewicz M, Asamoah-Boaheng M, Golding L, Lavoie PM, Petric M, Levett PN, Haig S, Barakauskas V, Karim ME, Jassem AN, Drews SJ, Sediqi S, Goldfarb DM | 2022 | Microbiol Spectr | View Correlation of SARS-CoV-2 Viral Neutralizing Antibody Titers with Anti-Spike Antibodies and ACE-2 Inhibition among Vaccinated Individuals | Researchers | Clinical research |
Estimating SARS-CoV-2 Seroprevalence in Canadian Blood Donors, April 2020 to March 2021: Improving Accuracy with Multiple Assays | Tuite AR, Fisman D, Abe KT, Rathod B, Pasculescu A, Colwill K, Gingras A-C, Yi Q-L, O’Brien SF, Drews SJ, Pride DT | 2022 | Microbiol Spectr | View Estimating SARS-CoV-2 Seroprevalence in Canadian Blood Donors, April 2020 to March 2021: Improving Accuracy with Multiple Assays | Researchers | Basic research |
Changing Patterns of SARS-CoV-2 Seroprevalence among Canadian Blood Donors during the Vaccine Era | Reedman CN, Drews SJ, Yi Q-L, Pambrun C, O’Brien SF | 2022 | Microbiol Spectr | View Changing Patterns of SARS-CoV-2 Seroprevalence among Canadian Blood Donors during the Vaccine Era | Researchers | Clinical research |
SARS-CoV-2 Virus-Like Particle Neutralizing Capacity in Blood Donors Depends on Serological Profile and Donor-Declared SARS-CoV-2 Vaccination History | Drews SJ, Hu Q, Samson R, Abe KT, Rathod B, Colwill K, Gingras A-C, Yi Q-L, O’Brien SF, Mostafa HH | 2022 | Microbiol Spectr | View SARS-CoV-2 Virus-Like Particle Neutralizing Capacity in Blood Donors Depends on Serological Profile and Donor-Declared SARS-CoV-2 Vaccination History | Researchers | Clinical research |
A Qualitative Comparison of the Abbott SARS-CoV-2 IgG II Quant Assay against Commonly Used Canadian SARS-CoV-2 Enzyme Immunoassays in Blood Donor Retention Specimens, April 2020 to March 2021 | Abe KT, Rathod B, Colwill K, Gingras A-C, Tuite A, Robbins NF, Orjuela G, Jenkins C, Conrod V, Yi Q-L, O’Brien SF, Drews SJ | 2022 | Microbiol Spectr | View A Qualitative Comparison of the Abbott SARS-CoV-2 IgG II Quant Assay against Commonly Used Canadian SARS-CoV-2 Enzyme Immunoassays in Blood Donor Retention Specimens, April 2020 to March 2021 | Researchers | Benchmarking and standard setting |
Comparative 6-Month Wild-Type and Delta-Variant Antibody Levels and Surrogate Neutralization for Adults Vaccinated with BNT162b2 versus mRNA-1273 | Grunau B, Golding L, Prusinkiewicz MA, Asamoah-Boaheng M, Armour R, Marquez AC, Jassem AN, Barakauskas V, O’Brien SF, Drews SJ, Haig S, Lavoie PM, Goldfarb DM | 2022 | Microbiol Spectr | View Comparative 6-Month Wild-Type and Delta-Variant Antibody Levels and Surrogate Neutralization for Adults Vaccinated with BNT162b2 versus mRNA-1273 | Researchers | Clinical research |
Cross-Canada Variability in Blood Donor SARS-CoV-2 Seroprevalence by Social Determinants of Health | O’Brien SF, Caffrey N, Yi Q-L, Bolotin S, Janjua NZ, Binka M, Thanh CQ, Stein DR, Lang A, Colquhoun A, Pambrun C, Reedman CN, Drews SJ | 2023 | Microbiol Spectr | View Cross-Canada Variability in Blood Donor SARS-CoV-2 Seroprevalence by Social Determinants of Health | Researchers | Clinical research |
Psychometric Evaluation of ITP Life Quality Index (ILQI) in a Global Survey of Patients with Immune Thrombocytopenia | Viana R, D'Alessio D, Grant L, Cooper N, Arnold D, Morgan M, Provan D, Cuker A, Hill QA, Tomiyama Y, Ghanima W | 2021 | Adv Ther | View Psychometric Evaluation of ITP Life Quality Index (ILQI) in a Global Survey of Patients with Immune Thrombocytopenia | Researchers | Clinical research |
Differential Leukocyte MicroRNA Responses Following Pan T Cell, Allorecognition and Allosecretome-Based Therapeutic Activation | Yang X, Toyofuku WM, Scott MD | 2021 | Arch Immunol Ther Exp | View Differential Leukocyte MicroRNA Responses Following Pan T Cell, Allorecognition and Allosecretome-Based Therapeutic Activation | Researchers | Basic research |
Complete Genome Sequence of Staphylococcus aureus PS/BAC/169/17/W, Isolated from a Contaminated Platelet Concentrate in England | Paredes C, Chi SI, Flint A, Weedmark K, McDonald C, Bearne J, Ramirez-Arcos S, Pagotto F, Baltrus DA | 2021 | Microbiol Resour Announc | View Complete Genome Sequence of Staphylococcus aureus PS/BAC/169/17/W, Isolated from a Contaminated Platelet Concentrate in England | Researchers | Benchmarking and standard setting |
Genome Sequence of Staphylococcus aureus Strain CBS2016-05, Isolated from Contaminated Platelet Concentrates in Canada | Yousuf B, Flint A, Weedmark K, Pagotto F, Ramirez-Arcos S, Hotopp JCD | 2021 | Microbiol Resour Announc | View Genome Sequence of Staphylococcus aureus Strain CBS2016-05, Isolated from Contaminated Platelet Concentrates in Canada | Researchers | Benchmarking and standard setting |
Complete Genome Sequence of Staphylococcus aureus CI/BAC/25/13/W, Isolated from Contaminated Platelet Concentrates in England | Paredes C, Chi SI, Flint A, Weedmark K, McDonald C, Bearne J, Ramirez-Arcos S, Pagotto F | 2021 | Microbiol Resour Announc | View Complete Genome Sequence of Staphylococcus aureus CI/BAC/25/13/W, Isolated from Contaminated Platelet Concentrates in England | Researchers | Benchmarking and standard setting |
Genome Sequence of Staphylococcus aureus Strain PS/BAC/317/16/W, Isolated from Contaminated Platelet Concentrates in England | Yousuf B, Flint A, Weedmark K, McDonald C, Bearne J, Pagotto F, Ramirez-Arcos S, Hotopp JCD | 2021 | Microbiol Resour Announc | View Genome Sequence of Staphylococcus aureus Strain PS/BAC/317/16/W, Isolated from Contaminated Platelet Concentrates in England | Researchers | Benchmarking and standard setting |