Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Hypoxia and low temperature upregulate transferrin to induce hypercoagulability at high altitude Li M, Tang X, Liao Z, Shen C, Cheng R, Fang M, Wang G, Li Y, Tang S, Xie L, Zhang Z, Kamau PM, Mwangi J, Lu Q, Li Y, Wang Y, MacKeigan DT, Cerenzia EG, Ni H, Lai R 2022 Blood View Researchers Basic research
RE: A better normal in Canada will need a better detection system for emerging and re-emerging respiratory pathogens O'Brien S, Goldman M, Drews S 2022 CMAJ View Researchers Clinical research
Clinical Outcomes of Umbilical Cord Blood Transplantation Using Ex Vivo Expansion: A Systematic Review and Meta-Analysis of Controlled Studies Saiyin T, Kirkham AM, Bailey AJM, Shorr R, Pineault N, Maganti HB, Allan DS 2023 Transplant Cell Ther View Researchers Clinical research
Contamination of platelet concentrates with Staphylococcus aureus induces significant modulations in platelet functionality Yousuf B, Pasha R, Pineault N, Ramirez-Arcos S 2022 Vox Sang View Researchers Basic research
A novel VSV/HIV pseudotype approach for the study of HIV microbicides without requirement for level 3 biocontainment Harrison AL, Henry S, Mahfoud R, Manis A, Albertini A, Gaudin Y, Lingwood CA, Branch DR 2011 Future Virol View Researchers Basic research
Cell-based therapy using umbilical cord blood for novel indications in regenerative therapy and immune modulation: an updated systematic scoping review of the literature Rizk M, Aziz J, Shorr R, Allan DS 2017 Biol Blood Marrow Transplant View Researchers Clinical research
Combination of 4Ts score and PF4/H-PaGIA for diagnosis and management of heparin-induced thrombocytopenia: prospective cohort study Linkins LA, Bates SM, Lee AY, Heddle NM, Wang G, Warkentin TE 2015 Blood View Researchers Clinical research
Early gamma-irradiation and subsequent storage of red cells in SAG?M additive solution potentiate energy imbalance, microvesiculation and susceptibility to stress?induced apoptotic cell death Qadri S, Chen D, Schubert P, Devine D, Sheffield W 2017 Vox Sang View Researchers Basic research
Expression screening of bacterial libraries of recombinant alpha-1 proteinase inhibitor variants for candidates with thrombin inhibitory capacity Bhakta V, Gierczak RF, Sheffield WP 2013 J Biotechnol View Researchers Basic research
How do I interpret a confidence interval? O'Brien SF, Yi QL 2016 Transfusion View Researchers Other
Innate immunity as orchestrator of bone marrow homing for hematopoietic stem/progenitor cells Ratajczak MZ, Kim C, Ratajczak J, Janowska-Wieczorek A 2013 Complement Therapeutics View Researchers Basic research
Large scale studies assessing anti-factor VIII antibody development in previously untreated haemophilia A: what has been learned, what to believe and how to learn more Iorio A, Fischer K, Makris M 2017 Br J Haematol View Researchers Clinical research
Medium conditioned with mesenchymal stromal cell-derived osteoblasts improves the expansion and engraftment properties of cord blood progenitors Dumont N, Boyer L, Emond H, Saltik BC, Pasha R, Bazin R, Mantovani D, Roy DC, Pineault N 2014 Exp Hematol View Researchers Basic research
Peripheral blood monocyte-derived chemokine blockade prevents murine antibody-mediated transfusion-related acute lung injury (TRALI) McKenzie CG, Kim M, Singh TK, Milev Y, Freedman J, Semple JW 2014 Blood View Researchers Basic research
Rationale and Design of the Informing Fresh versus Old Red Cell Management (INFORM) Trial: An International Pragmatic Randomized Trial Eikelboom JW, Cook RJ, Barty R, Liu Y, Arnold DM, Crowther MA, Devereaux PJ, Ellis M, Figueroa P, Gallus A, Hirsh J, Kurz A, Roxby D, Sessler DI, Sharon Y, Sobieraj-Teague M, Warkentin TE, Webert KE, Heddle NM 2016 Transfus Med Rev View Researchers Clinical research
Storage of red blood cells affects membrane composition, microvesiculation, and in vitro quality Almizraq R, Tchir JD, Holovati JL, Acker JP 2013 Transfusion View Researchers Basic research
The M358R variant of α1-proteinase inhibitor inhibits coagulation factor VIIa Sheffield WP, Bhakta V 2016 Biochem Biophys Res Commun View Researchers Basic research
Therapeutic cells via functional modification: Influence of molecular properties of polymer grafts on in vivo circulation, clearance, immunogenicity and antigen protection Chapanian R, Constantinescu I, Medvedev N, Scott MD, Brooks DE 2013 Biomacromolecules View Researchers Basic research
Managing antithrombotic therapy in immune thrombocytopenia: development of the TH2 risk assessment score Balitsky AK, Kelton JG, Arnold DM 2018 Blood View Researchers New or improved product or process
Improving Time to Antibiotics for Pediatric Oncology Patients With Fever and Suspected Neutropenia by Applying Lean Principles Geerlinks AV, Digout C, Bernstein M, Chan A, MacPhee S, Pambrun C, Gallant G, Wyatt L, Fernandez CV, Price VE 2018 Pediatric Emergency Care View Researchers New or improved product or process
The effect of tantalum incorporation on the physical and chemical properties of ternary silicon–calcium–phosphorous mesoporous bioactive glasses Mendonca A, Rahman MS, Alhalawani A, Rodriguez O, Gallant RC, Ni H, Clarkin OM, Towler MR 2019 J Biomed Mater Res B Appl Biomater View Researchers Basic research
Trends and outcomes in multicomponent blood transfusion: an 11-year cohort study of a large multisite academic center Perelman I, Saidenberg E, Tinmouth A, Fergusson D 2019 Transfusion View Researchers Clinical research
rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and Fc?Rs Spirig R, Campbell IK, Koernig S, Chen C-G, Lewis BJB, Butcher R, Muir I, Taylor S, Chia J, Leong D, Simmonds J, Scotney P, Schmidt P, Fabri L, Hofmann A, Jordi M, Spycher MO, Cattepoel S, Brasseit J, Panousis C, Rowe T, Branch DR, Baz Morelli A, Kaesermann F, Zuercher AW 2018 J Immunol View Researchers Basic research
Acquired factor XIII deficiency: A review Yan MTS, Rydz N, Goodyear D, Sholzberg M 2018 Transfus Apher Sci View Researchers Other
Comparative pharmacokinetics of two extended half-life FVIII concentrates (Eloctate and Adynovate) in adolescents with hemophilia A: Is there a difference? Carcao MD, Chelle P, Clarke E, Kim L, Tiseo L, Morfini M, Hossain T, Rand ML, Brown C, Edginton AN, Lillicrap D, Iorio A, Blanchette VS 2019 J Thromb Haemost View Researchers Clinical research
Barriers and enablers to source plasma donation by gay, bisexual and other men who have sex with men under revised eligibility criteria: protocol for a multiple stakeholder feasibility study Vesnaver E, Goldman M, O’Brien S, MacPherson P, Butler-Foster T, Lapierre D, Otis J, Devine DV, Germain M, Rosser A, MacDonagh R, Randall T, Osbourne-Sorrell W, Clement-Thorne B, Al-Bakri TB, Rubini KA, Hill NE, Presseau J 2020 Health Res Policy Syst View Researchers MSM research
The Missing Pieces to the Cold-Stored Platelet Puzzle Zhao H, Devine DV 2022 Int J Mol Sci View Researchers Basic research
Use of CRISPR/Cas9 gene editing to improve chimeric antigen-receptor T cell therapy: A systematic review and meta-analysis of preclinical studies Maganti HB, Kirkham AM, Bailey AJM, Shorr R, Kekre N, Pineault N, Allan DS 2022 Cytotherapy View Researchers Clinical research
The international experience of bacterial screen testing of platelet components with automated microbial detection systems: An update Kamel H, Ramirez-Arcos S, McDonald C, ISBT Transfusion-Transmitted Infectious Disease Bacterial Working Party Bacterial Subgroup 2022 Vox Sang View Researchers Benchmarking and standard setting
Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis Almizraq RJ, Frias Boligan K, Lewis BJB, Cen S, Whetstone H, Spirig R, Käsermann F, Campbell IK, von Gunten S, Branch DR 2023 Pharmacology View Researchers Basic research
THP-1 cells transduced with CD16A utilize Fcγ receptor I and III in the phagocytosis of IgG-sensitized human erythrocytes and platelets Gil Gonzalez L, Fernandez-Marrero Y, Norris PAA, Tawhidi Z, Shan Y, Cruz-Leal Y, Won KD, Frias-Boligan K, Branch DR, Lazarus AH 2022 PLoS One View Researchers Basic research
ABO O blood group as a risk factor for platelet reactivity in heparin-induced thrombocytopenia Karnes JH, Rollin J, Giles JB, Martinez KL, Steiner HE, Shaffer CM, Momozawa Y, Inai C, Bombin A, Shi M, Mosley JD, Stanaway I, Selleng K, Thiele T, Mushiroda T, Pouplard C, Heddle NM, Kubo M, Phillips EJ, Warkentin TE, Gruel Y, Greinacher A, Roden DM 2022 Blood View Researchers Basic research
Small Molecule Drugs That Inhibit Phagocytosis Loriamini M, Lewis-Bakker MM, Frias Boligan K, Wang S, Holton MB, Kotra LP, Branch DR 2023 Molecules View Researchers Basic research
Preparing small-dose red cell concentrates (RCCs) for neonatal and pediatric transfusions: Impact of RCC volume, storage, and irradiation Olafson C, William N, Howell A, Beaudin L, Gill B, Clarke G, Stephens S, Lopes-Carvalho D, Lane D, Schubert P, McTaggart K, Acker JP 2022 Transfusion View Researchers New or improved product or process
A bioinformatics approach to identify natural autoantibodies from healthy blood donors' sera reactive with the HCV NS5A-derived peptide by immunoassay Vasiljevic N, Veljkovic N, Kosec T, Ma XZ, Glisic S, Prljic J, Vujicic AD, Markovic L, Branch DR 2011 Viral Immunol View Researchers Basic research
A study protocol for a randomised controlled trial evaluating clinical effects of platelet transfusion products: the Pathogen Reduction Evaluation and Predictive Analytical Rating Score (PREPAReS) trial Ypma PF, van der Meer PF, Heddle NM, van Hilten JA, Stijnen T, Middelburg RA, Hervig T, van der Bom JG, Brand A, Kerkhoffs JL 2016 BMJ Open View Researchers Clinical research
Antibody binding to megakaryocytes in vivo in patients with immune thrombocytopenia Arnold DM, Nazi I, Toltl LJ, Ross C, Ivetic N, Smith JW, Liu Y, Kelton JG 2015 Eur J Haematol View Researchers Clinical research
Blood donors implicated in transfusion-related acute lung injury with patient-specific HLA antibodies are more broadly sensitized to HLA antigens compared to other blood donors Saw CL, Hannach B, Petrazsko T, Nickerson P 2013 Transfusion View Researchers Clinical research
Characterization of a long-acting recombinant human serum albumin-atrial natriuretic factor (ANF) expressed in Pichia pastoris de Bold MK, Sheffield WP, Martinuk A, Bhakta V, Eltringham-Smith L, de Bold AJ 2012 Regul Pept View Researchers Basic research
Complement C1q enhances homing-related responses of hematopoietic stem/progenitor cells Jalili A, Marquez-Curtis L, Shirvaikar N, Wysoczynski M, Ratajczak M, Janowska-Wieczorek A 2010 Transfusion View Researchers Basic research
Dengue virus binding and replication by platelets Simon AY, Sutherland MR, Pryzdial ELG 2015 Blood View Researchers Basic research
Distribution, origin and contamination risk of coagulase-negative staphylococci from platelet concentrates Rood IGH, de Korte D, Ramírez-Arcos S, Savelkoul PHM, Pettersson A 2011 J Med Microbiol View Researchers Basic research
Effectiveness and safety of thiotepa as conditioning treatment prior to stem cell transplant in patients with central nervous system lymphoma Kokolo MB, Fergusson D, O'Neill J, Tay J, Tinmouth AT, Stewart D, Bredeson C 2014 Leuk Lymphoma View Researchers Clinical research
Evaluating mesenchymal stem cell therapy for sepsis with preclinical meta-analyses prior to initiating a first-in-human trial Lalu MM, Sullivan KJ, Mei SHJ, Moher D, Straus A, Fergusson DA, Stewart DJ, Jazi M, MacLeod M, Winston B, Marshall J, Hutton B, Walley KR, McIntyre L 2016 eLife View Researchers Clinical research
Intravenous immunoglobulin treatment of spleen cells from patients with immune thrombocytopenia significantly increases the percentage of myeloid-derived suppressor cells Aslam R, Burack WR, Segel GB, McVey M, Spence SA, Semple JW 2017 Br J Haematol View Researchers Basic research
Microfluidic cell-phoresis enabling high-throughput analysis of red blood cell deformability and biophysical screening of antimalarial drugs Santoso AT, Deng X, Lee J-H, Matthews K, Duffy SP, Islamzada E, McFaul SM, Myrand-Lapierre M-E, Ma H 2015 Lab Chip View Researchers New or improved product or process
Multiplexed fluidic plunger mechanism for the measurement of red blood cell deformability Myrand-Lapierre ME, Deng X, Ang RR, Matthews K, Santoso AT, Ma H 2015 Lab Chip View Researchers New or improved product or process
Plant-based food cyanidin-3-glucoside modulates human platelet glycoprotein vi signaling and inhibits platelet activation and thrombus formation Yao Y, Chen Y, Adili R, McKeown T, Chen P, Zhu G, Li D, Ling W, Ni H, Yang Y 2017 J Nutr View Researchers Basic research
Polymer Brushes Hadjesfandiari N, Bajgai MP, Yu K, Brooks DE, Kizhakkedathu JN 2013 Encyclopedia of Polymer Science and Technology View Researchers Basic research
Proteomic analysis of red blood cells from donors exhibiting high hemolysis demonstrates a reduction in membrane?associated proteins involved in the oxidative response Chen D, Schubert P, Devine DV 2017 Transfusion View Researchers Basic research