Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Gender and BCR-ABL transcript type are correlated with molecular response to imatinib treatment in patients with chronic myeloid leukemia Lin HX, Sjaarda J, Dyck J, Stringer R, Hillis C, Harvey M, Carter R, Ainsworth P, Leber B, Pare G, Sadikovic B 2016 Eur J Haematol View Researchers Clinical research
Utilization of a surgical database to provide care and assess perioperative treatment and outcomes in patients with bleeding disorders Olasupo OO, Haddix C, Nakar C, Maahs J, Greist A, Ghafoor A, Donfield SM, Iorio A, Shapiro AD 2022 Eur J Haematol View Health care providers Benchmarking and standard setting
T cell-mediated autoimmunity in immune thrombocytopenia Vrbensky JR, Nazy I, Clare R, Larché M, Arnold DM 2022 Eur J Haematol View Researchers Clinical research
Comparison of single subject and population-based pharmacokinetics for optimizing prophylaxis with simoctocog alfa in patients with haemophilia A Astermark J, Olsson A, Chelle P, Täckström K, Walger M, Magnusson M, Iorio A 2021 Haemophilia View Researchers Clinical research
Comorbidities in persons with haemophilia aged 60 years or more compared with age-matched people from the general population Marchesini E, Oliovecchio E, Coppola A, Santagostino E, Radossi P, Castaman G, Valdre L, Santoro C, Tagliaferri A, Ettorre C, Zanon E, Barillari G, Cantori I, Caimi TM, Sottilotta G, Iorio A, Mannucci PM 2018 Haemophilia View Health care providers Clinical research
Understanding stakeholder important outcomes and perceptions of equity, acceptability and feasibility of a care model for haemophilia management in the US: a qualitative study Lane SJ, Sholapur NS, Yeung CH, Iorio A, Heddle NM, Sholzberg M, Pai M 2016 Haemophilia View Health care providers Other
A brief survey of clinicians' perceptions of parent preferences for involvement in obstetrical and perinatal management decisions in haemophilia Lucier KJ, Movilla RV, Parvizian MK, Siddiqui R, Gabriele EH, Bourque M, MacIsaac J, Moorehead PC, Chan AK, Heddle NM, Lane SJ 2018 Haemophilia View Health care providers Clinical research
Target plasma factor levels for personalized treatment in haemophilia: a Delphi consensus statement Iorio A, Iserman E, Blanchette V, Dolan G, Escuriola Ettingshausen C, Hermans C, Negrier C, Oldenburg J, Reininger A, Rodriguez-Merchan C, Spannagl M, Valentino LA, Young G, Steinitz-Trost KN, Gringeri A 2017 Haemophilia View Health care providers Clinical research
Patterns of joint damage in severe haemophilia A treated with prophylaxis Goren R, Pullenayegum E, Blanchette VS, Dover S, Carcao M, Israels SJ, Chan A, Rivard GE, Steele M, Cloutier S, Klaassen RJ, Sinha R, Price VE, Laferriere N, Paradis E, Wu JK, Feldman BM 2021 Haemophilia View Health care providers Clinical research
A systematic review of definitions and reporting of bleeding outcome measures in haemophilia Chai-Adisaksopha C, Hillis C, Thabane L, Iorio A 2015 Haemophilia View Health care providers Clinical research
First analysis of 10-year trends in national factor concentrates usage in haemophilia: data from CHARMS, the Canadian Hemophilia Assessment and Resource Management System Traore AN, Chan AKC, Webert KE, Heddle N, Ritchie B, St-Louis J, Teitel J, Lillicrap D, Iorio A, Walker I 2014 Haemophilia View Health care providers Clinical research
Sexual issues in people with haemophilia: Awareness and strategies for overcoming communication barriers Blamey G, Van Tassel B, Sagermann E, Stain AM, Waterhouse L, Iorio A 2022 Haemophilia View Researchers Ethical, legal and social implications research
What should men living with haemophilia need to know? The perspectives of Canadian men with haemophilia Arnold E, Lane S, Webert KE, Chan A, Walker I, Tufts J, Rubin S, Poon MC, Heddle NM 2014 Haemophilia View Health care providers Other
Immunogenicity, efficacy and safety of Nuwiq® (human-cl rhFVIII) in previously untreated patients with severe haemophilia A-Interim results from the NuProtect Study Liesner RJ, Abashidze M, Aleinikova O, Altisent C, Belletrutti MJ, Borel-Derlon A, Carcao M, Chambost H, Chan AKC, Dubey L, Ducore J, Fouzia NA, Gattens M, Gruel Y, Guillet B, Kavardakova N, El Khorassani M, Klukowska A, Lambert T, Lohade S, Sigaud M, Turea V, Wu JKM, Vdovin V, Pavlova A, Jansen M, Belyanskaya L, Walter O, Knaub S, Neufeld EJ 2017 Haemophilia View Researchers Clinical research
Prophylaxis use of clotting factor replacement products in people with non-severe haemophilia: A review of the literature Iorio A, Königs C, Reding MT, Rotellini D, Skinner MW, Mancuso ME, Berntorp E 2023 Haemophilia View Health care providers Clinical research
What should men living with severe haemophilia need to know? The perspectives of Canadian haemophilia health care providers Lane S, Arnold E, Webert KE, Chan A, Walker I, Heddle NM 2013 Haemophilia View Health care providers Other
Past, present and future of haemophilia gene therapy: From vectors and transgenes to known and unknown outcomes Pierce GF, Iorio A 2018 Haemophilia View Health care providers New or improved product or process
Factor product utilization and health outcomes in patients with haemophilia A and B on extended half-life concentrates: A Canadian observational study of real-world outcomes Sun H, Yang M, Poon M-C, Lee A, Robinson KS, Sholzberg M, Wu J, Iorio A, Blanchette V, Carcao M, Klaassen RJ, Jackson S 2021 Haemophilia View Researchers Clinical research
Switching to extended half-life products in Canada - preliminary data Keepanasseril A, Stoffman J, Bouskill V, Carcao M, Iorio A, Jackson S 2017 Haemophilia View Health care providers Clinical research
Test-retest properties of the Patient Reported Outcomes, Burdens and Experiences (PROBE) questionnaire and its constituent domains Chai-Adisaksopha C, Skinner MW, Curtis R, Frick N, Nichol MB, Noone D, O'Mahony B, Page D, Stonebraker J, Thabane L, Crowther MA, Iorio A 2019 Haemophilia View Researchers Clinical research
Treatment decision-making among Canadian youth with severe haemophilia: a qualitative approach Lane SJ, Walker I, Chan AK, Heddle NM, Poon MC, Minuk L, Jardine L, Arnold E, Sholapur N, Webert KE 2015 Haemophilia View Health care providers Clinical research
Converting factor and nonfactor usage into a single metric to facilitate benchmarking the resources consumed for haemophilia care across jurisdictions and over time Stonebraker JS, O'Mahony B, Noone D, Iorio A 2021 Haemophilia View Researchers Benchmarking and standard setting
Evaluation of the sexual health in people living with hemophilia Germini F, Chai-Adisaksopha C, Pete D, Curtis R, Frick N, Nichol MB, Noone D, O'Mahony B, Page D, Stonebraker JS, Thabane L, Crowther MA, Skinner MW, Iorio A 2021 Haemophilia View Researchers Clinical research
The importance of haemophilia treatment centre administrators in patient care Almonte T, Decker K, Seroski W, Walker I, Webert K, Bos C, Strike K, Waterhouse L, Goldsmith R, Chan AK 2012 Haemophilia View Health care providers Other
Challenges and key lessons from the design and implementation of an international haemophilia registry supported by a pharmaceutical company Hay CRM, Shima M, Makris M, Jiménez-Yuste V, Oldenburg J, Fischer K, Iorio A, Skinner MW, Santagostino E, von Mackensen S, Kessler CM 2020 Haemophilia View Researchers Clinical research
Rate and appropriateness of polypharmacy in older patients with hemophilia compared with age-matched controls Mannucci PM, Nobili A, Marchesini E, Oliovecchio E, Cortesi L, Coppola A, Santagostino E, Radossi P, Castaman G, Valdrè L, Santoro C, Tagliaferri A, Ettorre C, Zanon E, Barillari G, Cantori I, Caimi TM, Sottilotta G, Peyvandi F, Iorio A 2018 Haemophilia View Health care providers Clinical research
Exploring some intersections between pharmacokinetics, factor VIII measurement and human morphometrics - impact of recent advances in haemophilia study design on our understanding of optimal haemophilia treatment Iorio A, Edginton AN 2017 Haemophilia View Researchers Clinical research
Point of care ultrasound in haemophilia: Building a strong foundation for clinical implementation Lawson W, Uy M, Strike K, Iorio A, Stein N, Koziol L, Chan A 2017 Haemophilia View Health care providers Clinical research
Emicizumab state-of-the-art update Mahlangu J, Iorio A, Kenet G 2022 Haemophilia View Health care providers Clinical research
Switching from standard to extended half-life FVIII prophylaxis in haemophilia A: Comparison of factor product use, bleed rates and pharmacokinetics Nummi V, Lehtinen AE, Iorio A, Szanto T, Lassila R 2022 Haemophilia View Researchers Clinical research
Core outcome set for gene therapy in haemophilia: Results of the coreHEM multistakeholder project Iorio A, Skinner MW, Clearfield E, Messner D, Pierce GF, Witkop M, Tunis S 2018 Haemophilia View Health care providers Clinical research
A case of vertical transmission of Chagas Disease contracted via blood transfusion in Canada Fearon MA, Scalia V, Huang M, Dines I, Ndao M 2013 Can J Infect Dis Med Microbiol View Health care providers Clinical research
The effect of timing of gamma-irradiation on hemolysis and potassium release in leukoreduced red cell concentrates stored in SAGM Serrano K, Chen D, Hansen AL, Levin E, Turner TR, Kurach JDR, Acker JP, Devine DV 2014 Vox Sang View Researchers New or improved product or process
Vox Sanguinis international forum on provision of granulocytes for transfusion and their clinical use: summary Morton S, Stanworth S, Lozano M, Harrison S, Hong F, Dennington P, McQuilten Z, Worel N, Compernolle V, Kutner J, Yokoyama A, Nahirniak S, Germain M, Hume H, Robitaille N, Wilson A, Tinmouth A, Massey E, Boulat C, Woimant G, Tiberghien P, Schulze T, Bux J, Pierelli L, Ballester C, Netelenbos T, West K, Conry-Cantilena C, Eder A, Haley N, Yazer M, Triulzi D 2017 Vox Sang View Blood operators Clinical research
Guidance for the procurement of COVID-19 convalescent plasma: differences between high- and low-middle-income countries Bloch EM, Goel R, Wendel S, Burnouf T, Al-Riyami AZ, Ang AL, DeAngelis V, Dumont LJ, Land K, Lee CK, Oreh A, Patidar G, Spitalnik SL, Vermeulen M, Hindawi S, Van den Berg K, Tiberghien P, Vrielink H, Young P, Devine D, So-Osman C 2020 Vox Sang View Health care providers Clinical research
TACO-BEL-3: a feasibility study and a retrospective audit of diuretics for patients receiving blood transfusion at ten hospitals Khandelwal A, Lin Y, Cserti-Gazdewich C, Al Moosawi M, Armali C, Arnold D, Callum J, Dallas KL, Lieberman L, Pavenski K, Rioux-Massé B, Shehata N, Shih AW, Pendergrast J 2020 Vox Sang View Health care providers Clinical research
The international experience of bacterial screen testing of platelet components with automated microbial detection systems: An update Kamel H, Ramirez-Arcos S, McDonald C, ISBT Transfusion-Transmitted Infectious Disease Bacterial Working Party Bacterial Subgroup 2022 Vox Sang View Researchers Benchmarking and standard setting
Bacterial contamination in platelet concentrates Pietersz RNI, Reesink HW, Panzer S, Oknaian S, Kuperman S, Gabriel C, Rapaille A, Lambermont M, Deneys V, Sondag D, Rami­rez-Arcos S, Goldman M, Delage G, Bernier F, Germain M, Vuk T, Georgsen J, Morel P, Naegelen C, Bardiaux L, Cazenave JP, Dreier J, Vollmer T, Knabbe C, Seifried E, Hourfar K, Lin CK, Spreafico M, Raffaele L, Berzuini A, Prati D, Satake M, de Korte D, van der Meer PF, Kerkhoffs JL, Blanco L, Kjeldsen-Kragh J, Svard-Nilsson AM, McDonald CP, Symonds I, Moule R, Brailsford S, Yomtovian R, Jacobs MR 2014 Vox Sang View Blood operators Benchmarking and standard setting
Group O RBCs: where is universal donor blood being used Barty RL, Pai M, Liu Y, Arnold DM, Cook RJ, Zeller MP, Heddle NM 2017 Vox Sang View Health care providers Clinical research
Not all red cell concentrate units are equivalent: international survey of processing and in vitro quality data Shih AW, Apelseth TO, Cardigan R, Marks DC, Bégué S, Greinacher A, de Korte D, Seltsam A, Shaz BH, Wikman A, Barty RL, Heddle NM, Acker JP, The QMiP Investigators on behalf of the Biomedical Excellence for Safer Transfusion Collaborative 2019 Vox Sang View Researchers Benchmarking and standard setting
An international comparison of anti-SARS-COV-2 assays used for seroprevalence surveys from blood component providers Lewin A, Drews SJ, Lieshout-Krikke R, Erikstrup C, Saeed S, Fady H, Uzicanin S, Custer B, O’Brien SF, the Surveillance Risk Assessment Policy tVS-gotI, Transfusion Transmitted Infectious Diseases Working Party 2021 Vox Sang View Blood operators Benchmarking and standard setting
HIV residual risk in Canada for apheresis source plasma donation without deferral for men who have sex with men Aubé E, Lewin A, O'Brien SF, Grégoire Y, Pillonel J, Steele WR, Custer B, Davison KL, Germain M, Seed CR, Camirand Lemyre F, the Surveillance RA, Policy Subgroup of the ISBT Transfusion Transmitted Infectious Diseases Working Party 2022 Vox Sang View Blood operators MSM research
Alternatives in blood operations when choosing non-DEHP bags van der Meer PF, Devine DV, on behalf of the BEST Collaborative 2017 Vox Sang View Blood operators New or improved product or process
Manufacturing method affects mitochondrial DNA release and extracellular vesicle composition in stored red blood cells Bakkour S, Acker JP, Chafets DM, Inglis HC, Norris PJ, Lee TH, Busch MP 2016 Vox Sang View Researchers Basic research
Changing the deferral for men who have sex with men - an improved model to estimate HIV residual risk Davison KL, Gregoire Y, Germain M, Custer B, O'Brien SF, Steele WR, Pillonel J, Seed CR 2019 Vox Sang View Blood operators New or improved product or process
Impacts of COVID-19 and elective surgery cancellations on platelet supply and utilization in the Canadian Province of British Columbia Shopsowitz KE, Lim C, Shih AW, Fishbane N, Berry BR, Bigham M, Petraszko T, Trudeau J, Wyatt M, Yan MTS, Morrison D 2022 Vox Sang View Blood operators Benchmarking and standard setting
An investigation of red blood cell concentrate quality during storage in paediatric-sized polyvinylchloride bags plasticized with alternatives to di-2-ethylhexyl phthalate (DEHP) Serrano K, Levin E, Chen D, Hansen A, Turner TR, Kurach J, Reidel A, Boecker WF, Acker JP, Devine DV 2015 Vox Sang View Researchers Basic research
Prothrombin complex concentrate for emergent reversal of warfarin: an international survey of hospital protocols Gorlin J, Kinney S, Fung M, Tinmouth A 2017 Vox Sang View Health care providers Clinical research
Survey of blood centre readiness regarding removal of DEHP from blood bag sets: The BEST Collaborative Study Razatos A, Acker JP, de Korte D, Bégué S, Noorman F, Doyle B, Zia M, Min K, The Biomedical Excellence for Safer Transfusion Collaborative 2022 Vox Sang View Researchers New or improved product or process
International Forum on the Management of Major Haemorrhage: Responses Green L, Stanworth S, McQuilten Z, Lin V, Tucker H, Jackson B, Badawi M, Hindawi S, Chaurasia R, Patidar G, Pandey HC, Fasola F, Miyata S, Matsumoto M, Matsushita T, Rahimi-Levene N, Peer V, Pavenski K, Callum J, Thompson T, Murphy M, Staves J, Maegele M, Abeyakoon C, Rushford K, Wood E, Nuñez MA, Mellado S, Saa E, Triyono T, Pratomo B, Apelseth TO, Dunbar N 2022 Vox Sang View Health care providers Benchmarking and standard setting