Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
An uncertain association between influenza season, recent influenza vaccination campaigns, and unconfirmed repeat reactive syphilis serology assay results in Canadian blood donors Drews SJ, Bodnar M, Gill B, Carson D, Hawes G, Yi QL, Tran V, Zhou HY, Bigham M, O'Brien SF 2022 Transfusion View Researchers Benchmarking and standard setting
Newer formulations of intravenous iron: a review of their chemistry and key safety aspects – hypersensitivity, hypophosphatemia, and cardiovascular safety Blumenstein I, Shanbhag S, Langguth P, Kalra PA, Zoller H, Lim W 2021 Expert Opin Drug Saf View Researchers Basic research
A Qualitative Comparison of the Abbott SARS-CoV-2 IgG II Quant Assay against Commonly Used Canadian SARS-CoV-2 Enzyme Immunoassays in Blood Donor Retention Specimens, April 2020 to March 2021 Abe KT, Rathod B, Colwill K, Gingras A-C, Tuite A, Robbins NF, Orjuela G, Jenkins C, Conrod V, Yi Q-L, O’Brien SF, Drews SJ 2022 Microbiol Spectr View Researchers Benchmarking and standard setting
Blood is a politic of place-making: Blackness, queerness and the construction of the donor Dryden OH 2022 Harriet’s Legacies: Race, Historical Memory, and Futures in Canada View Researchers MSM research
Automated closed volume reduction process for apheresis stem cell grafts: From development to clinical implementation Howell A, Letcher B, Murphy K, Elmoazzen H, Petraszko T, Acker JP, Pineault N, Holovati JL 2022 Transfusion View Researchers New or improved product or process
A data-informed system to manage scarce blood product allocation in a randomized controlled trial of convalescent plasma Li N, Zeller MP, Shih AW, Heddle NM, St. John M, Bégin P, Callum J, Arnold DM, Akbari-Moghaddam M, Down DG, Jamula E, Devine DV, Tinmouth A 2022 Transfusion View Researchers Clinical research
Current status of rapid bacterial detection methods for platelet components: A 20-year review by the ISBT Transfusion-Transmitted Infectious Diseases Working Party Subgroup on Bacteria Schmidt M, Ramirez-Arcos S, Stiller L, McDonald C, ISBT Transfusion-Transmitted Infectious Diseases Working Party Subgroup on Bacteria 2022 Vox Sang View Researchers Benchmarking and standard setting
An official American Thoracic Society/International Society for Heart and Lung Transplantation/Society of Critical Care Medicine/Association of Organ and Procurement Organizations/United Network of Organ Sharing Statement: ethical and policy considerations in organ donation after circulatory determination of death Gries CJ, White DB, Truog RD, Dubois J, Cosio CC, Dhanani S, Chan KM, Corris P, Dark J, Fulda G, Glazier AK, Higgins R, Love R, Mason DP, Nakagawa TA, Shapiro R, Shemie S, Tracy MF, Travaline JM, Valapour M, West L, Zaas D, Halpern SD, American Thoracic Society Health Policy Committee 2013 Am J Respir Crit Care Med View Researchers Benchmarking and standard setting
Attitudes toward Reciprocity Systems for Organ Donation and Allocation for Transplantation Burkell JA, Chandler JA, Shemie SD 2013 J Health Polit Policy Law View Researchers Other
Cellular immune dysfunction in immune thrombocytopenia (ITP) McKenzie CGJ, Guo L, Freedman J, Semple JW 2013 Br J Haematol View Researchers Basic research
CXCR4 transfection of cord blood mesenchymal stromal cells with the use of cationic liposome enhances their migration toward stromal cell-derived factor-1 Marquez-Curtis LA, Gul-Uludag H, Xu P, Chen J, Janowska-Wieczorek A 2013 Cytotherapy View Researchers Basic research
Dicer cleavage by calpain determines platelet microRNA levels and function in diabetes Elgheznawy A, Shi L, Hu J, Wittig I, Laban H, Pircher J, Mann A, Provost P, Randriamboavonjy V, Fleming I 2015 Circ Res View Researchers Basic research
Further evidence that paroxysmal nocturnal haemoglobinuria is a disorder of defective cell membrane lipid rafts Ratajczak MZ, Borkowska S, Mierzejewska K, Kucia M, Mendek-Czajkowska E, Suszynska M, Sharma VA, Deptala A, Song W, Platzbecker U, Larratt L, Janowska-Wieczorek A, Maciejewski J, Ratajczak J 2015 J Cell Mol Med View Researchers Basic research
Integrin PSI domain has endogenous thiol isomerase function and is a novel target for anti-platelet therapy Zhu G, Zhang Q, Reddy EC, Carrim N, Chen Y, Xu XR, Xu M, Wang Y, Hou Y, Ma L, Li Y, Rui M, Petruzziello T, Lavalle C, Stratton TW, Lei X, Reheman A, Chen P, Zhu C, Wilkins JA, Hynes RO, Freedman J, Ni H 2017 Blood View Researchers Basic research
Leaving nothing to chance: how to randomize a clinical trial Toltl LJ, Arnold DM 2012 Transfusion View Researchers Other
Membrane Type-1 Matrix Metalloproteinase Expression in Acute Myeloid Leukemia and Its Upregulation by Tumor Necrosis Factor-? Marquez-Curtis LA, Shirvaikar N, Turner AR, Mirza I, Surmawala A, Larratt LM, Janowska-Wieczorek A 2012 Cancers View Researchers Basic research
Monovalent Fc receptor blockade by an anti-Fc? receptor/albumin fusion protein ameliorates murine ITP with abrogated toxicity Yu X, Menard M, Prechl J, Bhakta V, Sheffield WP, Lazarus AH 2016 Blood View Researchers Basic research
Red blood cell antibody induced anemia causes differential degrees of tissue hypoxia in kidney and brain Mistry N, Mazer CD, Sled JG, Lazarus AH, Cahill LS, Solish M, Zhou Y-Q, Romanova N, Hare AG, Doctor A, Fisher JA, Brunt KR, Simpson JA, Hare GMT 2018 Am J Physiol Regul Integr Comp Physiol View Researchers Basic research
Strict anaerobic Staphylococcus saccharolyticus isolates recovered from contaminated platelet concentrates fail to multiply during platelet storage Ali H, Rood IG, de Korte D, Ramirez-Arcos S 2012 Transfusion View Researchers Basic research
The cellular pathophysiology of immune thrombocytopenia Semple JW 2013 ISBT Sci Ser View Researchers Basic research
Thermal reversal of polyvalent choline phosphate, a multivalent universal biomembrane adhesive Yu X, Zou Y, Horte S, Janzen J, Kizhakkedathu JN, Brooks DE 2013 Biomacromolecules View Researchers Basic research
Verotoxin A subunit protects lymphocytes and T cell lines against X4 HIV infection in vitro Shi PL, Binnington B, Sakac D, Katsman Y, Ramkumar S, Gariepy J, Kim M, Branch DR, Lingwood C 2012 Toxins (Basel) View Researchers Basic research
ResearchUnit: One in a million: Modelling rare blood flow Blake J, Clarke G 2019 Blood.ca website View Researchers Clinical research
Effect of liposome treatment on hemorheology and metabolic profile of human red blood cells during hypothermic storage Da Silveira Cavalcante L, Acker J, Holovati J 2018 Biopreserv Biobank View Researchers Basic research
Reducing red blood cell folate testing: a case study in utilisation management Ismail O, Chin-Yee I, Gob A, Bhayana V, Rutledge A 2019 BMJ Open Quality View Researchers Basic research
Pathophysiology of immune thrombocytopenia Li J, Sullivan JA, Ni H 2018 Curr Opin Hematol View Researchers Other
Concentré de recherche : Plasma : c'est dans la poche Sheffield W, Jenkins C 2018 Blood.ca website View Researchers Basic research
Concentré de recherche: Combattre l'inflammation par l'inflammation Lazarus A 2019 Blood.ca website View Researchers Clinical research
Comparative seasonalities of influenza A, B and 'common cold' coronaviruses - setting the scene for SARS-CoV-2 infections and possible unexpected host immune interactions Liu Y, Lam TTY, Lai FYL, Krajden M, Drews SJ, Hatchette TF, Fraaij PLA, van Kampen JJA, Badarch D, Nymadawa P, Tee KK, Lee HK, Koay ESC, Jennings L, Koopmans M, Tang JW 2020 J Infect View Researchers Clinical research
Direct comparison of two extended half-life PEGylated recombinant FVIII products: a randomized, crossover pharmacokinetic study in patients with severe hemophilia A Solms A, Shah A, Berntorp E, Tiede A, Iorio A, Linardi C, Ahsman M, Mancuso ME, Zhivkov T, Lissitchkov T 2020 Ann Hematol View Researchers Clinical research
A prospective observational study of the incidence, natural history, and risk factors for intravenous immunoglobulin-mediated hemolysis Pendergrast J, Armali C, Callum J, Cserti-Gazdewich C, Jiwajee A, Lieberman L, Lau W, Lin Y, Parmar N, Pavenski K, Riden LS, Shehata N, Willie-Ramharack K, Tomlinson G, Tong TN, Binnington B, Branch DR 2021 Transfusion View Researchers Clinical research
Tantalum-containing mesoporous bioactive glass powder for hemostasis Nagrath M, Gallant R, Yazdi AR, Mendonca A, Rahman S, Chiu L, Waldman SD, Ni H, Towler MR 2021 J Biomater Appl View Researchers Basic research
Genome Sequence of Staphylococcus aureus Strain PS/BAC/317/16/W, Isolated from Contaminated Platelet Concentrates in England Yousuf B, Flint A, Weedmark K, McDonald C, Bearne J, Pagotto F, Ramirez-Arcos S, Hotopp JCD 2021 Microbiol Resour Announc View Researchers Benchmarking and standard setting
Frequency of positive anti-PF4/polyanion antibody tests after COVID-19 vaccination with ChAdOx1 nCoV-19 and BNT162b2 Thiele T, Ulm L, Holtfreter S, Schönborn L, Kuhn SO, Scheer C, Warkentin TE, Bröker BM, Becker K, Aurich K, Selleng K, Hübner N-O, Greinacher A 2021 Blood View Researchers Clinical research
Heparin induced thrombocytopenia in relation to SARS-CoV-2 infection and ABO blood group Ray JG, Warkentin TE, Park AL 2021 Thromb Res View Researchers Clinical research
Staphylococcus epidermidis undergoes global changes in gene expression during biofilm maturation in platelet concentrates Loza-Correa M, Yousuf B, Ramirez-Arcos S 2021 Transfusion View Researchers Basic research
Current and Future Perspectives for the Cryopreservation of Cord Blood Stem Cells Jahan S, Kaushal R, Pasha R, Pineault N 2021 Transfus Med Rev View Researchers New or improved product or process
Reply to: Concerns about estimating relative risk of death associated with convalescent plasma for COVID-19 Bégin P, Callum J, Cook R, Jamula E, Liu Y, Finzi A, Arnold DM 2022 Nat Med View Researchers Clinical research
The impact of biological age of red blood cell on in vitro endothelial activation markers Alshalani A, Beuger BM, Tuip-de Boer AM, van Bruggen R, Acker JP, Juffermans NP 2023 Front Physiol View Researchers Basic research
Removing the men who have sex with men blood donation deferral: Informing risk models using Canadian public health surveillance data Caffrey N, Goldman M, Lewin A, Grégoire Y, Yi QL, O’Brien SF 2022 Transfus Clin Biol View Researchers MSM research
SARS-CoV-2 seroprevalence among Vancouver public school staff in British Columbia, Canada: a cross-sectional study Goldfarb DM, Mâsse LC, Watts AW, Hutchison SM, Muttucomaroe L, Bosman ES, Barakauskas VE, Choi A, Dhillon N, Irvine MA, Reicherz F, O’Reilly C, Sediqi S, Xu RY, Razzaghian HR, Sadarangani M, Coombs D, O’Brien SF, Lavoie PM 2022 BMJ Open View Researchers Clinical research
Doxorubicin-Induced Platelet Activation and Clearance Relieved by Salvianolic Acid Compound: Novel Mechanism and Potential Therapy for Chemotherapy-Associated Thrombosis and Thrombocytopenia Ma W, Rousseau Z, Slavkovic S, Shen C, Yousef GM, Ni H 2022 Pharmaceuticals View Researchers Basic research
Allogeneic platelet transfusions prevent murine T-cell–mediated immune thrombocytopenia Guo L, Yang L, Speck ER, Aslam R, Kim M, McKenzie CGJ, Lazarus AH, Ni H, Hou M, Freedman J, Semple JW 2014 Blood View Researchers Basic research
Antibody-mediated immune suppression is improved when blends of anti-RBC monoclonal antibodies are used in mice Bernardo L, Amash A, Marjoram D, Lazarus AH 2016 Blood View Researchers Basic research
Blood groups and susceptibility to virus infection: new developments Branch DR 2010 Curr Opin Hematol View Researchers Basic research
Concentré de recherche: Amélioration des résultats pour les patients présentant des troubles auto-immuns de la fonction plaquettaire Arnold D 2017 Blood.ca website View Researchers Basic research
Dengue virus replication by platelets Pryzdial ELG, Sutherland MR, Simon AY 2017 ISBT Sci Ser View Researchers Basic research
DJ-1/PARK7 Impairs Bacterial Clearance in Sepsis Amatullah H, Shan Y, Beauchamp BL, Gali PL, Gupta S, Maron-Gutierrez T, Speck ER, Fox-Robichaud AE, Tsang JLY, Mei SHJ, Mak TW, Rocco PRM, Semple JW, Zhang H, Hu P, Marshall JC, Stewart DJ, Harper M-E, Liaw PC, Liles WC, dos Santos CC, Canadian Critical Care Translational Biology Group (CCCTBG) 2017 Am J Respir Crit Care Med View Researchers Basic research
Effects of pathogen reduction systems on platelet microRNAs, mRNAs, activation, and function Osman A, Hitzler WE, Meyer CU, Landry P, Corduan A, Laffont B, Boilard E, Hellstern P, Vamvakas EC, Provost P 2015 Platelets View Researchers Basic research
FcgRIIa proteolysis as a diagnostic biomarker for heparin-induced thrombocytopenia Nazi I, Arnold DM, Smith JW, Horsewood P, Moore JC, Warkentin TE, Crowther MA, Kelton JG 2013 J Thromb Haemost View Researchers Basic research