Our Research Publications
Updated November 2023
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Title | Authors | Year | Journal | Link to Article | Intended Audience Sort descending | Purpose |
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CD8(+) T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia | Qiu J, Liu X, Li X, Zhang X, Han P, Zhou H, Shao L, Hou Y, Min Y, Kong Z, Wang Y, Wei Y, Liu X, Ni H, Peng J, Hou M | 2016 | Sci Rep | View CD8(+) T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia | Researchers | Basic research |
Coagulation factor X Arg386 specifically affects activation by the intrinsic pathway: a novel patient mutation | Vanden Hoek AL, Talbot K, Carter IS, Vickars L, Carter CJ, Jackson SC, Macgillivray RT, Pryzdial EL | 2012 | J Thromb Haemost | View Coagulation factor X Arg386 specifically affects activation by the intrinsic pathway: a novel patient mutation | Researchers | Basic research |
c-Src and Pyk2 protein tyrosine kinases play protective roles in early HIV-1 infection of CD4+ T cell lines | McCarthy SDS, Jung D, Sakac D, Branch DR | 2014 | J Acquir Immune Defic Syndr | View c-Src and Pyk2 protein tyrosine kinases play protective roles in early HIV-1 infection of CD4+ T cell lines | Researchers | Basic research |
Drugs in ITP: Mechanisms of Action | Crow AR, Lazarus AH | 2013 | Immune Thrombocytopenia (ITP) | View Drugs in ITP: Mechanisms of Action | Researchers | Other |
Enhancing blood donor skin disinfection using natural oils | Alabdullatif M, Boujezza I, Mekni M, Taha M, Kumaran D, Yi QL, Landoulsi A, Ramirez-Arcos S | 2017 | Transfusion | View Enhancing blood donor skin disinfection using natural oils | Researchers | New or improved product or process |
Exploring some intersections between pharmacokinetics, factor VIII measurement and human morphometrics - impact of recent advances in haemophilia study design on our understanding of optimal haemophilia treatment | Iorio A, Edginton AN | 2017 | Haemophilia | View Exploring some intersections between pharmacokinetics, factor VIII measurement and human morphometrics - impact of recent advances in haemophilia study design on our understanding of optimal haemophilia treatment | Researchers | Clinical research |
High-quality randomized controlled trials in pediatric critical care: a survey of barriers and facilitators | Duffett M, Choong K, Foster J, Meade M, Menon K, Parker M, Cook DJ | 2017 | Pediatr Crit Care Med | View High-quality randomized controlled trials in pediatric critical care: a survey of barriers and facilitators | Researchers | Clinical research |
Inhibition of phagocytic recognition of anti-D opsonized Rh D+ RBC by polymer-mediated immunocamouflage | Li L, Noumsi GT, Kwok YYE, Moulds JM, Scott MD | 2015 | Am J Hematol | View Inhibition of phagocytic recognition of anti-D opsonized Rh D+ RBC by polymer-mediated immunocamouflage | Researchers | Basic research |
Label-free assessment of red blood cell storage lesions by deep learning | Doan M, Sebastian JA, Pinto PN, McQuin C, Goodman A, Wolkenhauer O, Parsons MJ, Acker JP, Rees P, Hennig H, Kolios MC, Carpenter AE | 2018 | bioRxiv | View Label-free assessment of red blood cell storage lesions by deep learning | Researchers | New or improved product or process |
Mechanisms of platelet recovery in ITP associated with therapy | Pang SJY, Lazarus AH | 2010 | Ann Hematol | View Mechanisms of platelet recovery in ITP associated with therapy | Researchers | Basic research |
Nucleic acid extraction from buccal tissue for prediction of red blood cell phenotype | Berardi P, Cote J, Clarke G, Scalia V, Liwski R, Goldman M | 2017 | Transfusion | View Nucleic acid extraction from buccal tissue for prediction of red blood cell phenotype | Researchers | New or improved product or process |
Role of G protein-coupled vasoactive intestinal peptide receptors in HIV integration | Branch DR | 2011 | Future Virol | View Role of G protein-coupled vasoactive intestinal peptide receptors in HIV integration | Researchers | Basic research |
The platelet "sugar high" in diabetes | Ni H | 2012 | Blood | View The platelet "sugar high" in diabetes | Researchers | Other |
Thrombolysis by chemically modified coagulation factor Xa | Pryzdial ELG, Meixner SC, Talbot K, Eltringham-Smith LJ, Baylis JR, Lee FMH, Kastrup CJ, Sheffield WP | 2016 | J Thromb Haemost | View Thrombolysis by chemically modified coagulation factor Xa | Researchers | Basic research |
Serologic problems associated with administration of intravenous immune globulin (IVIg) | Branch DR | 2019 | Immunohematology | View Serologic problems associated with administration of intravenous immune globulin (IVIg) | Researchers | Clinical research |
A Retrospective Chart Review of Transfusion Practices in the Palliative Care Unit Setting | Sirianni G, Perri G, Callum J, Gardner S, Berall A, Selby D | 2018 | Am J Hosp Palliat Care | View A Retrospective Chart Review of Transfusion Practices in the Palliative Care Unit Setting | Researchers | Clinical research |
Whole blood donors with antibodies | Yan M | 2019 | Blood.ca website | View Whole blood donors with antibodies | Researchers | Basic research |
Coenzyme Q10 Upregulates Platelet cAMP/PKA Pathway and Attenuates Integrin alpha II beta 3 Signaling and Thrombus Growth | Ya F, Xu XR, Shi Y, Gallant RC, Song F, Zuo X, Zhao Y, Tian Z, Zhang C, Xu X, Ling W, Ni H, Yang Y | 2019 | Mol Nutr Food Res | View Coenzyme Q10 Upregulates Platelet cAMP/PKA Pathway and Attenuates Integrin alpha II beta 3 Signaling and Thrombus Growth | Researchers | Basic research |
Feasibility of photoacoustic imaging for the non-invasive quality management of stored blood bags | Pinto RN, Hysi E, Bagga K, Sebastian JA, Douplik A, Acker JP, Kolios MC | 2019 | Vox Sang | View Feasibility of photoacoustic imaging for the non-invasive quality management of stored blood bags | Researchers | New or improved product or process |
Proposal of a two-step process for the diagnosis of sepsis-induced disseminated intravascular coagulation | Iba T, Levy JH, Yamakawa K, Thachil J, Warkentin TE, Levi M, Scientific and Standardization Committee on DIC of the International Society on Thrombosis and Haemostasis | 2019 | J Thromb Haemost | View Proposal of a two-step process for the diagnosis of sepsis-induced disseminated intravascular coagulation | Researchers | New or improved product or process |
Targeting ABL1 or ARG Tyrosine Kinases to Restrict HIV-1 Infection in Primary CD4+ T?Cells or in Humanized NSG Mice | McCarthy SDS, Leontyev D, Nicoletti P, Binnington B, Kozlowski HN, Ostrowski M, Cochrane A, Branch DR, Wong RW | 2019 | J Acquir Immune Defic Syndr | View Targeting ABL1 or ARG Tyrosine Kinases to Restrict HIV-1 Infection in Primary CD4+ T?Cells or in Humanized NSG Mice | Researchers | Basic research |
Clinically approved IVIg delivered to the hippocampus with focused ultrasound promotes neurogenesis in a model of Alzheimer’s disease | Dubey S, Heinen S, Krantic S, McLaurin J, Branch DR, Hynynen K, Aubert I | 2020 | PLoS Pathog | View Clinically approved IVIg delivered to the hippocampus with focused ultrasound promotes neurogenesis in a model of Alzheimer’s disease | Researchers | Basic research |
Proliferative and Regenerative Effect of Acetonic Extract of Feijoa sellowiana on Stem Cells | Rasekh H, Hoseini Farahi M, Mehrabani D, Massoumi SJ, Ramzi M, Acker JP | 2020 | World J Plast Surg | View Proliferative and Regenerative Effect of Acetonic Extract of Feijoa sellowiana on Stem Cells | Researchers | Basic research |
Stepwise Reversion of Multiply Mutated Recombinant Antitrypsin Reveals a Selective Inhibitor of Coagulation Factor XIa as Active as the M358R Variant | Hamada M, Bhakta V, Andres SN, Sheffield WP | 2021 | Front Cardiovasc Med | View Stepwise Reversion of Multiply Mutated Recombinant Antitrypsin Reveals a Selective Inhibitor of Coagulation Factor XIa as Active as the M358R Variant | Researchers | Basic research |
Estimating SARS-CoV-2 Seroprevalence in Canadian Blood Donors, April 2020 to March 2021: Improving Accuracy with Multiple Assays | Tuite AR, Fisman D, Abe KT, Rathod B, Pasculescu A, Colwill K, Gingras A-C, Yi Q-L, O’Brien SF, Drews SJ, Pride DT | 2022 | Microbiol Spectr | View Estimating SARS-CoV-2 Seroprevalence in Canadian Blood Donors, April 2020 to March 2021: Improving Accuracy with Multiple Assays | Researchers | Basic research |
Current challenges of severe acute respiratory syndrome coronavirus 2 seroprevalence studies among blood donors: A scoping review | Saeed S, Uzicanin S, Lewin A, Lieshout-Krikke R, Faddy H, Erikstrup C, Osiowy C, Seed CR, Steele WR, Davison K, Custer B, O'Brien SF, Assessment SR, Policy Sub-group of the Transfusion Transmitted Infectious Diseases Working Party of the International Society of Blood Transfusion | 2022 | Vox Sang | View Current challenges of severe acute respiratory syndrome coronavirus 2 seroprevalence studies among blood donors: A scoping review | Researchers | Basic research |
Novel Mechanisms of Thrombopoietin Generation: The Essential Role of Kupffer Cells | Karakas D, Li J, Ni H | 2021 | Blood | View Novel Mechanisms of Thrombopoietin Generation: The Essential Role of Kupffer Cells | Researchers | Basic research |
Anti-platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein | Greinacher A, Selleng K, Mayerle J, Palankar R, Wesche J, Reiche S, Aebischer A, Warkentin TE, Muenchhoff M, Hellmuth JC, Keppler OT, Duerschmied D, Lother A, Rieg S, Gawaz MP, Mueller KAL, Scheer CS, Napp M, Hahnenkamp K, Lucchese G, Vogelgesang A, Flöel A, Lovreglio P, Stufano A, Marschalek R, Thiele T | 2021 | Blood | View Anti-platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein | Researchers | Clinical research |
Risk factors for neonatal thrombosis: A retrospective study conducted in a single Canadian intensive care unit | Bhatia K, Solanki S, Paes B, Chan AKC, Bhatt MD | 2022 | Pediatr Blood Cancer | View Risk factors for neonatal thrombosis: A retrospective study conducted in a single Canadian intensive care unit | Researchers | Clinical research |
Mitapivat versus Placebo for Pyruvate Kinase Deficiency | Al-Samkari H, Galactéros F, Glenthøj A, Rothman JA, Andres O, Grace RF, Morado-Arias M, Layton DM, Onodera K, Verhovsek M, Barcellini W, Chonat S, Judge MP, Zagadailov E, Xu R, Hawkins P, Beynon V, Gheuens S, van Beers EJ | 2022 | N Engl J Med | View Mitapivat versus Placebo for Pyruvate Kinase Deficiency | Researchers | Clinical research |
Chemokines IP-10/CXCL10 and IL-8/CXCL8 are potential novel biomarkers of warm autoimmune hemolytic anemia | Branch DR, Leger RM, Sakac d, Yi Q, Duong T, Yeung RSM, Binnington B, Bloch EM | 2022 | Blood Adv | View Chemokines IP-10/CXCL10 and IL-8/CXCL8 are potential novel biomarkers of warm autoimmune hemolytic anemia | Researchers | Basic research |
Adjudicating the Diagnosis of Immune Thrombocytopenia in a Clinical Research Study | Gabe C, Mahamad S, John M, Duncan J, Kelton J, Arnold D | 2023 | TH Open | View Adjudicating the Diagnosis of Immune Thrombocytopenia in a Clinical Research Study | Researchers | Clinical research |
Hepatitis B Blood Donor Screening Data: An Under-Recognized Resource for Canadian Public Health Surveillance | O’Brien SF, Reedman CN, Osiowy C, Bolotin S, Yi Q-L, Lourenço L, Lewin A, Binka M, Caffrey N, Drews SJ | 2023 | Viruses | View Hepatitis B Blood Donor Screening Data: An Under-Recognized Resource for Canadian Public Health Surveillance | Researchers | Clinical research |
Rapid potency assessment of autologous peripheral blood stem cells by intracellular flow cytometry: the PBSC-IL-3-pSTAT5 assay | Simard C, Fournier D, Pineault N, Trépanier P | 2022 | Cytotherapy | View Rapid potency assessment of autologous peripheral blood stem cells by intracellular flow cytometry: the PBSC-IL-3-pSTAT5 assay | Researchers | New or improved product or process |
A role for red cell clearance in antibody-mediated inhibition of erythrocyte alloimmunization? | Marjoram D, Cruz-Leal Y, Bernardo L, Lazarus AH | 2017 | ISBT Sci Ser | View A role for red cell clearance in antibody-mediated inhibition of erythrocyte alloimmunization? | Researchers | Basic research |
Anti-A and anti-B: what are they and where do they come from? | Branch DR | 2015 | Transfusion | View Anti-A and anti-B: what are they and where do they come from? | Researchers | Other |
Bacteria can proliferate in thawed cryoprecipitate stored at room temperature for longer than 4 h | Ramirez-Arcos S, Jenkins C, Sheffield W | 2017 | Vox Sang | View Bacteria can proliferate in thawed cryoprecipitate stored at room temperature for longer than 4 h | Researchers | Basic research |
Chapter 33: Synthesis of N-(4-Methoxybenzyl)-2-(α-d-glucopyranosyl) acetamide | Roy R, Vidal S, Briard JG, Shiao TC, Ben RN | 2015 | Carbohydrate Chemistry: Proven Synthetic Methods, Volume 3 | View Chapter 33: Synthesis of N-(4-Methoxybenzyl)-2-(α-d-glucopyranosyl) acetamide | Researchers | Basic research |
Comparison of methods for the purification of alpha-1 acid glycoprotein from human plasma | McCurdy TR, Bhakta V, Eltringham-Smith LJ, Gataiance S, Fox-Robichaud AE, Sheffield WP | 2011 | J Biomed Biotechnol | View Comparison of methods for the purification of alpha-1 acid glycoprotein from human plasma | Researchers | Basic research |
Dissociation of SERPINE1 mRNA from the translational repressor proteins Ago2 and TIA-1 upon platelet activation | Corduan A, Ple H, Laffont B, Wallon T, Plante I, Landry P, Provost P | 2015 | Thromb Haemost | View Dissociation of SERPINE1 mRNA from the translational repressor proteins Ago2 and TIA-1 upon platelet activation | Researchers | Basic research |
Effect of texture of platelet bags on bacterial and platelet adhesion | Hadjesfandiari N, Schubert P, Fallah Toosi S, Chen Z, Culibrk B, Ramirez-Arcos S, Devine DV, Brooks DE | 2016 | Transfusion | View Effect of texture of platelet bags on bacterial and platelet adhesion | Researchers | Basic research |
Fanconi anemia proteins and their interacting partners: a molecular puzzle | Kaddar T, Carreau M | 2012 | Anemia | View Fanconi anemia proteins and their interacting partners: a molecular puzzle | Researchers | Basic research |
Hyaluronic acid and thrombin upregulate MT1-MMP through PI3K and Rac-1 signaling and prime the homing-related responses of cord blood hematopoietic stem/progenitor cells | Shirvaikar N, Marquez-Curtis LA, Ratajczak MZ, Janowska-Wieczorek A | 2011 | Stem Cells Dev | View Hyaluronic acid and thrombin upregulate MT1-MMP through PI3K and Rac-1 signaling and prime the homing-related responses of cord blood hematopoietic stem/progenitor cells | Researchers | Basic research |
Liposomes alter thermal phase behavior and composition of red blood cell membranes | Stoll C, Stadnick H, Kollas O, Holovati JL, Glasmacher B, Acker JP, Wolkers WF | 2011 | Biochim Biophys Acta | View Liposomes alter thermal phase behavior and composition of red blood cell membranes | Researchers | Basic research |
Microfluidic analysis of red blood cell deformability as a means to assess hemin-induced oxidative stress resulting from Plasmodium falciparum intraerythrocytic parasitism | Matthews K, Duffy SP, Myrand-Lapierre M-E, Ang RR, Li L, Scott MD, Ma H | 2017 | Integr Biol | View Microfluidic analysis of red blood cell deformability as a means to assess hemin-induced oxidative stress resulting from Plasmodium falciparum intraerythrocytic parasitism | Researchers | Basic research |
MT1-MMP association with membrane lipid rafts facilitates G-CSF?induced hematopoietic stem/progenitor cell mobilization | Shirvaikar N, Marquez-Curtis LA, Shaw AR, Turner AR, Janowska-Wieczorek A | 2010 | Exp Hematol | View MT1-MMP association with membrane lipid rafts facilitates G-CSF?induced hematopoietic stem/progenitor cell mobilization | Researchers | Basic research |
Plant food anthocyanins inhibit platelet granule secretion in hypercholesterolaemia: Involving the signalling pathway of PI3K–Akt | Song F, Zhu Y, Shi Z, Tian J, Deng X, Ren J, Andrews MC, Ni H, Ling W, Yang Y | 2014 | Thromb Haemost | View Plant food anthocyanins inhibit platelet granule secretion in hypercholesterolaemia: Involving the signalling pathway of PI3K–Akt | Researchers | Basic research |
Proteolytic modulation of factor Xa-antithrombin complex enhances fibrinolysis in plasma | Talbot K, Meixner SC, Pryzdial EL | 2013 | Biochim Biophys Acta | View Proteolytic modulation of factor Xa-antithrombin complex enhances fibrinolysis in plasma | Researchers | Basic research |
Red blood cell transfusion and mortality effect in aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis protocol | English SW, Chassé M, Turgeon AF, Tinmouth A, Boutin A, Pagliarello G, Fergusson D, McIntyre L | 2015 | Syst Rev | View Red blood cell transfusion and mortality effect in aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis protocol | Researchers | Clinical research |
Retention of thrombin inhibitory activity by recombinant serpins expressed as integral membrane proteins tethered to the surface of mammalian cells | Gierczak RF, Sutherland JS, Bhakta V, Toltl LJ, Liaw PC, Sheffield WP | 2011 | J Thromb Haemost | View Retention of thrombin inhibitory activity by recombinant serpins expressed as integral membrane proteins tethered to the surface of mammalian cells | Researchers | Basic research |