Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
A flow cytometric method for platelet counting in platelet concentrates van der Meer PF, Karssing-van Leeuwen W, Kurtz J, Spengler H-P, Blair A, Devine D, Harrison P, Lambrecht B, VandenBroeke T, de Wildt J, de Korte D, on behalf of the Biomedical Excellence for Safer Transfusion C 2012 Transfusion View Researchers New or improved product or process
A trial to determine whether septic shock-reversal is quicker in pediatric patients randomized to an early goal-directed fluid-sparing strategy versus usual care (SQUEEZE): study protocol for a pilot randomized controlled trial Parker MJ, Thabane L, Fox-Robichaud A, Liaw P, Choong K 2016 Trials View Researchers Clinical research
Alpha-1 Acid Glycoprotein Reduces Hepatic Leukocyte Recruitment in Murine Models of Either Early Endotoxemia or Early Sepsis McCurdy TR, Patrick AL, Eltringham-Smith LJ, Bhakta V, Sheffield WP, Fox-Robichaud AE 2014 Microcirculation View Researchers Basic research
Antigens protected functional red blood cells by the membrane grafting of compact hyperbranched polyglycerols Chapanian R, Constantinescu I, Brooks DE, Scott MD, Kizhakkedathu J 2013 J Vis Exp View Researchers Basic research
Buffy coat (top/bottom)- and whole-blood filtration (top/top)-produced red cell concentrates differ in size of extracellular vesicles Bicalho B, Pereira AS, Acker JP 2015 Vox Sang View Researchers Basic research
Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis Murphy AJ, Bijl N, Yvan-Charvet L, Welch CB, Bhagwat N, Reheman A, Wang Y, Shaw JA, Levine RL, Ni H, Tall AR, Wang N 2013 Nat Med View Researchers Basic research
Concentré de recherche: La sécrétion de cellules immunitaires peut protéger les patients contre le syndrome respiratoire post-transfusionnel Semple J 2017 Blood.ca website View Researchers Basic research
Design, implementation, and evaluation of a knowledge translation intervention to increase organ donation after cardiocirculatory death in Canada: a study protocol Squires JE, Grimshaw JM, Taljaard M, Linklater S, Chasse M, Shemie SD, Knoll GA 2014 Implement Sci View Researchers Other
Efficiency of riboflavin and ultraviolet light treatment against high levels of biofilm?derived Staphylococcus epidermidis in buffy coat platelet concentrates Taha M, Culibrk B, Kalab M, Schubert P, Yi QL, Goodrich R, Ramirez?Arcos S 2017 Vox Sang View Researchers New or improved product or process
Evaluation of CONSORT compliance in TRANSFUSION Jaffer AM, Wang G, Barty RL, Shih AW 2015 Transfusion View Researchers Other
Hematopoietic Stem Cell Mobilization and Homing after Transplantation: The Role of MMP-2, MMP-9, and MT1-MMP Shirvaikar N, Marquez-Curtis LA, Janowska-Wieczorek A 2012 Biochem Res Int View Researchers Basic research
IgG-Mediated Immune Suppression to Erythrocytes by Polyclonal Antibodies Can Occur in the Absence of Activating or Inhibitory Fc? Receptors in a Full Mouse Model Bernardo L, Yu H, Amash A, Zimring JC, Lazarus AH 2015 J Immunol View Researchers Basic research
In silico analysis suggests repurposing of ibuprofen for prevention and treatment of EBOLA virus disease Veljkovic V, Goeijenbier M, Glisic S, Veljkovic N, Perovic VR, Sencanski M, Branch DR, Paessler S 2015 F1000Res View Researchers Basic research
Involvement of the contact phase and intrinsic pathway in herpes simplex virus-initiated plasma coagulation Gershom ES, Sutherland MR, Lollar P, Pryzdial EL 2010 J Thromb Haemost View Researchers Basic research
Maestro tissue factor reaches new hEIGHT Pryzdial ELG 2017 Blood View Researchers Basic research
Migration, proliferation and differentiation of cord blood mesenchymal stromal cells treated with histone deacetylase inhibitor valproic acid Marquez-Curtis LA, Qiu Y, Xu A, Janowska-Wieczorek A 2014 Stem Cells Int View Researchers Basic research
Platelet concentrate functionality assessed by thromboelastography or rotational thromboelastometry Arbaeen AF, Serrano K, Levin E, Devine DV 2016 Transfusion View Researchers Basic research
rIgG1 Fc hexamer inhibits antibody-mediated autoimmune disease via effects on complement and FcgammaRs Spirig R, Campbell IK, Koernig S, Chen CG, Lewis BJB, Butcher R, Muir I, Taylor S, Chia J, Leong D, Simmonds J, Scotney P, Schmidt P, Fabri L, Hofmann A, Jordi M, Spycher MO, Cattepoel S, Brasseit J, Panousis C, Rowe T, Branch DR, Baz Morelli A, Kasermann F, Zuercher AW 2018 J Immunol View Researchers Basic research
Sialylation-independent mechanism involved in the amelioration of murine immune thrombocytopenia using intravenous gammaglobulin Leontyev D, Katsman Y, Ma XZ, Miescher S, Kasermann F, Branch DR 2012 Transfusion View Researchers Basic research
Towards a prophylactic treatment of HPA-related foetal and neonatal alloimmune thrombocytopenia Kjeldsen-Kragh J, Ni H, Skogen B 2012 Curr Opin Hematol View Researchers Other
Test-retest properties of the Patient Reported Outcomes, Burdens and Experiences (PROBE) questionnaire and its constituent domains Chai-Adisaksopha C, Skinner MW, Curtis R, Frick N, Nichol MB, Noone D, O'Mahony B, Page D, Stonebraker J, Thabane L, Crowther MA, Iorio A 2019 Haemophilia View Researchers Clinical research
Cellular immune responses to platelet factor 4 and heparin complexes in patients with heparin-induced thrombocytopenia Nazy I, Clare R, Staibano P, Warkentin TE, Larché M, Moore JC, Smith JW, Whitlock RP, Kelton JG, Arnold DM 2018 J Thromb Haemost View Researchers Clinical research
Modulating Intracellular Ice Growth with Cell-Permeating Small-Molecule Ice Recrystallization Inhibitors Poisson JS, Acker JP, Briard JG, Meyer JE, Ben RN 2018 Langmuir View Researchers Basic research
The Monocyte Monolayer Assay: Past, Present and Future Tong TN, Cen S, Branch DR 2018 Transfus Med Rev View Researchers Basic research
Corrigendum to "Comparison of mammalian and bacterial expression library screening to detect recombinant alpha-1 proteinase inhibitor variants with enhanced thrombin inhibitory capacity" [J. Biotechnol. 208 (2015) 54-62] Gierczak RF, Bhakta V, Xie M, Sheffield WP 2020 J Biotechnol View Researchers Basic research
Modulating Intracellular Ice Growth with Cell-Permeating Small-Molecule Ice Recrystallization Inhibitors Poisson JS, Acker JP, Briard JG, Meyer JE, Ben RN 2019 Langmuir View Researchers Basic research
Using pharmacokinetics for tailoring prophylaxis in people with hemophilia switching between clotting factor products: A scoping review Yu JK, Iorio A, Edginton AN, Wapps co?investigators 2019 Res Pract Thromb Haemost View Researchers Clinical research
The Effect of Age and Type of Media on Growth Kinetics of Human Amniotic Fluid Stem cells Borzou B, Mehrabani D, Zare S, Zamani-Pereshkaft M, Acker JP 2020 Biopreserv Biobank View Researchers Basic research
HIT: still stringing us along Warkentin TE 2020 Blood View Researchers Clinical research
Thrombospondin-1/CD47 signaling modulates transmembrane cation conductance, survival, and deformability of human red blood cells Bissinger R, Petkova-Kirova P, Mykhailova O, Oldenborg P-A, Novikova E, Donkor DA, Dietz T, Bhuyan AAM, Sheffield WP, Grau M, Artunc F, Kaestner L, Acker JP, Qadri SM 2020 Cell Signal View Researchers Basic research
Successful prenatal therapy for anti-CD36-mediated severe FNAIT by deglycosylated antibodies in a novel murine model Xu X, Chen D, Ye X, Xia W, Xu Y, Chen Y, Shao Y, Deng J, Ding H, Liu J, Wang J, Ni H, Fu Y, Santoso S 2021 Blood View Researchers Basic research
From demand forecasting to inventory ordering decisions for red blood cells through integrating machine learning, statistical modeling, and inventory optimization Li N, Arnold DM, Down DG, Barty R, Blake J, Chiang F, Courtney T, Waito M, Trifunov R, Heddle NM 2022 Transfusion View Researchers New or improved product or process
The authors reply Iba T, Levy JH, Warkentin TE 2022 Crit Care Med View Researchers Clinical research
SARS-CoV-2 seroprevalence among Vancouver public school staff in British Columbia, Canada Goldfarb DM, Mâsse LC, Watts AW, Hutchison SM, Muttucomaroe L, Bosman ES, Barakauskas VE, Choi A, Irvine MA, Reicherz F, Coombs D, O’Reilly C, Sediqi S, Razzaghian HR, Sadarangani M, O’Brien SF, Lavoie PM 2021 medRxiv View Researchers Clinical research
A scalable serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccination Colwill K, Galipeau Y, Stuible M, Gervais C, Arnold C, Rathod B, Abe KT, Wang JH, Pasculescu A, Maltseva M, Rocheleau L, Pelchat M, Fazel-Zarandi M, Iskilova M, Barrios-Rodiles M, Bennett L, Yau K, Cholette F, Mesa C, Li AX, Paterson A, Hladunewich MA, Goodwin PJ, Wrana JL, Drews SJ, Mubareka S, McGeer AJ, Kim J, Langlois M-A, Gingras A-C, Durocher Y 2022 Clin Transl Immunol View Researchers New or improved product or process
SARS-CoV-2 spike-dependent platelet activation in COVID-19 vaccine-induced thrombocytopenia Appelbaum J, Arnold DM, Kelton JG, Gernsheimer T, Jevtic SD, Ivetic N, Smith JW, Nazy I 2022 Blood Adv View Researchers Basic research
A Higher Antibody Response Is Generated With a 6- to 7-Week (vs Standard) Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Dosing Interval Grunau B, Asamoah-Boaheng M, Lavoie PM, Karim ME, Kirkham TL, Demers PA, Barakauskas V, Marquez AC, Jassem AN, O’Brien SF, Drews SJ, Haig S, Cheskes S, Goldfarb DM 2021 Clin Infect Dis View Researchers Clinical research
The evaluation of constant coronary artery flow versus constant coronary perfusion pressure during normothermic ex situ heart perfusion Qi X, Hatami S, Bozso S, Buchko M, Forgie KA, Olafson C, Khan M, Himmat S, Wang X, Nobes DS, Acker JP, Nagendran J, Freed DH 2022 J Heart Lung Transplant View Researchers Basic research
Activated platelets can deliver mRNA regulatory Ago2-microRNA complexes to endothelial cells via microparticles Laffont B, Corduan A, Plé H, Duchez AC, Cloutier N, Boilard E, Provost P 2013 Blood View Researchers Basic research
Assessing the Rationale and Effectiveness of Frozen Plasma Transfusions: An Evidence-based Review Tinmouth A 2016 Hematol Oncol Clin North Am View Researchers Clinical research
CD44 Antibody Inhibition of Macrophage Phagocytosis Targets Fc? Receptor– and Complement Receptor 3–Dependent Mechanisms Amash A, Wang L, Wang Y, Bhakta V, Fairn GD, Hou M, Peng J, Sheffield WP, Lazarus AH 2016 J Immunol View Researchers Basic research
Crosstalk between Platelets and the Immune System: Old Systems with New Discoveries Li C, Li J, Li Y, Lang S, Yougbare I, Zhu G, Chen P, Ni H 2012 Adv Hematol View Researchers Basic research
Development of a high-yield expression and purification system for platelet factor 4 Huynh A, Arnold DM, Moore JC, Smith JW, Kelton JG, Nazy I 2017 Platelets View Researchers Basic research
Heterogeneity in Studies of Mesenchymal Stromal Cells to Treat or Prevent Graft-versus-Host Disease: A Scoping Review of the Evidence Rizk M, Monaghan M, Shorr R, Kekre N, Bredeson CN, Allan DS 2016 Biol Blood Marrow Transplant View Researchers Basic research
Inhibition of allogeneic cytotoxic T cell (CD8+) proliferation via polymer-induced Treg (CD4+) cells Kang N, Toyofuku WM, Yang X, Scott MD 2017 Acta Biomat View Researchers Basic research
Mechanism of hemoglobin-induced cellular injury in desiccated red blood cells Kanias T, Acker JP 2010 Free Radic Biol Med View Researchers Basic research
Modulation of microRNA Activity by Semi-microRNAs Plante I, Ple H, Landry P, Gunaratne PH, Provost P 2012 Front Genet View Researchers Basic research
Novel insight into stem cell mobilization-Plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization due to activation of complement cascade/membrane attack complex Ratajczak MZ, Lee H, Wysoczynski M, Wan W, Marlicz W, Laughlin MJ, Kucia M, Janowska-Wieczorek A, Ratajczak J 2010 Leukemia View Researchers Basic research
PEGylation prevents bacteria-induced platelet activation and biofilm formation in platelet concentrates Greco CA, Maurer-Spurej E, Scott MD, Kalab M, Nakane N, Rami­rez-Arcos SM 2011 Vox Sang View Researchers Basic research
Platelet transfusion reactions do not occur more often in recipients transfused with apheresis versus buffy coat platelet concentrates Cserti-Gazdewich C, Escorcia A, Pendergrast J, Lieberman L, Skeate R, Lin Y, Callum J 2016 Transfusion View Researchers Clinical research