Our Research Publications

Updated August 2025

Title Authors Year Journal Link to Article Intended Audience Purpose
Vascular endothelial dysfunction in beta-thalassemia occurs despite increased eNOS expression and preserved vascular smooth muscle cell reactivity to NO Stoyanova E, Trudel M, Felfly H, Lemsaddek W, Garcia D, Cloutier G 2012 PLoS One View Researchers Basic research
Encapsulation of factor IX-engineered mesenchymal stem cells in fibrinogen-alginate microcapsules enhances their viability and transgene secretion Sayyar B, Dodd M, Wen J, Ma S, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G 2012 J Tissue Eng View Researchers Basic research
Evidence for a novel mechanism independent of myocardial iron in beta-thalassemia cardiac pathogenesis Stoyanova E, Cloutier G, Felfly H, Lemsaddek W, Ah-Son N, Trudel M 2012 PLoS One View Researchers Basic research
Sialylation-independent mechanism involved in the amelioration of murine immune thrombocytopenia using intravenous gammaglobulin Leontyev D, Katsman Y, Ma XZ, Miescher S, Kasermann F, Branch DR 2012 Transfusion View Researchers Basic research
Towards a prophylactic treatment of HPA-related foetal and neonatal alloimmune thrombocytopenia Kjeldsen-Kragh J, Ni H, Skogen B 2012 Curr Opin Hematol View Researchers Other
Leaving nothing to chance: how to randomize a clinical trial Toltl LJ, Arnold DM 2012 Transfusion View Researchers Other
Membrane Type-1 Matrix Metalloproteinase Expression in Acute Myeloid Leukemia and Its Upregulation by Tumor Necrosis Factor-? Marquez-Curtis LA, Shirvaikar N, Turner AR, Mirza I, Surmawala A, Larratt LM, Janowska-Wieczorek A 2012 Cancers View Researchers Basic research
Strict anaerobic Staphylococcus saccharolyticus isolates recovered from contaminated platelet concentrates fail to multiply during platelet storage Ali H, Rood IG, de Korte D, Ramirez-Arcos S 2012 Transfusion View Researchers Basic research
Verotoxin A subunit protects lymphocytes and T cell lines against X4 HIV infection in vitro Shi PL, Binnington B, Sakac D, Katsman Y, Ramkumar S, Gariepy J, Kim M, Branch DR, Lingwood C 2012 Toxins (Basel) View Researchers Basic research
Rituximab maintenance for relapsed refractory thrombotic thrombocytopenic purpura Bhagirath VC, Kelton JG, Moore J, Arnold DM 2012 Transfusion View Health care providers Clinical research
Validation and implementation of a new hemoglobinometer for donor screening at Canadian Blood Services Goldman M, Uzicanin S, Yi QL, Acker JP, Ramirez-Arcos S 2012 Transfusion View Blood operators New or improved product or process
Prothrombin complex concentrates reduce blood loss in murine coagulopathy induced by warfarin, but not in that induced by dabigatran etexilate Lambourne MD, Eltringham-Smith LJ, Gataiance S, Arnold DM, Crowther MA, Sheffield WP 2012 J Thromb Haemost View Researchers Basic research
The potential utility of methoxypoly(ethylene glycol)-mediated prevention of rhesus blood group antigen RhD recognition in transfusion medicine Wang D, Toyofuku WM, Scott MD 2012 Biomaterials View Researchers Basic research
Cationic liposome-mediated CXCR4 gene delivery into hematopoietic stem/progenitor cells: implications for clinical transplantation and gene therapy Gul-Uludag H, Xu P, Marquez-Curtis LA, Xing J, Janowska-Wieczorek A, Chen J 2012 Stem Cells Dev View Researchers Basic research
Preparation of blood products for transfusion: is there a best method? Devine DV, Serrano K 2012 Biologicals View Blood operators Other
Synergistic effects of liposomes, trehalose, and hydroxyethyl starch for cryopreservation of human erythrocytes Stoll C, Holovati JL, Acker JP, Wolkers WF 2012 Biotechnol Prog View Researchers New or improved product or process
Mesenchymal stromal cells derived from umbilical cord blood migrate in response to complement C1q Qiu Y, Marquez-Curtis LA, Janowska-Wieczorek A 2012 Cytotherapy View Researchers Basic research
The importance of haemophilia treatment centre administrators in patient care Almonte T, Decker K, Seroski W, Walker I, Webert K, Bos C, Strike K, Waterhouse L, Goldsmith R, Chan AK 2012 Haemophilia View Health care providers Other
Evaluating the role of IL-11, a novel cytokine in the IL-6 family, in a mouse model of spinal cord injury Cho N, Nguyen DH, Satkunendrarajah K, Branch DR, Fehlings MG 2012 J Neuroinflammation View Researchers Basic research
Tissue factor and glycoprotein C on herpes simplex virus type 1 are protease-activated receptor 2 cofactors that enhance infection Sutherland MR, Ruf W, Pryzdial EL 2012 Blood View Researchers Basic research
Red Blood Cell Storage Lesions and Related Transfusion Issues: A Canadian Blood Services Research and Development Symposium Pavenski K, Saidenberg E, Lavoie M, Tokessy M, Branch DR 2012 Transfus Med Rev View Health care providers Other
Acquired hemophilia A Webert KE 2012 Semin Thromb Hemost View Health care providers Other
Influence of architecture of high molecular weight linear and branched polyglycerols on their biocompatibility and biodistribution Imran ul-haq M, Lai BF, Chapanian R, Kizhakkedathu JN 2012 Biomaterials View Researchers Basic research
Preserving and using germplasm and dissociated embryonic cells for conserving Caribbean and Pacific coral Hagedorn M, Carter V, Martorana K, Paresa MK, Acker J, Baums IB, Borneman E, Brittsan M, Byers M, Henley M, Laterveer M, Leong JA, McCarthy M, Meyers S, Nelson BD, Petersen D, Tiersch T, Uribe RC, Woods E, Wildt D 2012 PLoS One View Researchers Basic research
Transfusion reactions: a comparative observational study of blood components produced before and after implementation of semiautomated production from whole blood Semple E, Bowes-Schmidt A, Yi QL, Shimla S, Devine DV 2012 Transfusion View Blood operators New or improved product or process
The repertoire and features of human platelet microRNAs Ple H, Landry P, Benham A, Coarfa C, Gunaratne PH, Provost P 2012 PLoS One View Researchers Basic research
Decreased indoleamine 2,3-dioxygenase expression in dendritic cells and role of indoleamine 2,3-dioxygenase-expressing dendritic cells in immune thrombocytopenia Xu SQ, Wang CY, Zhu XJ, Dong XY, Shi Y, Peng J, Qin P, Sun JZ, Guo C, Ni H, Hou M 2012 Ann Hematol View Researchers Basic research
Thrombin generates previously unidentified C5 products that support the terminal complement activation pathway Krisinger MJ, Goebeler V, Lu Z, Meixner SC, Myles T, Pryzdial EL, Conway EM 2012 Blood View Researchers Basic research
Reduction of thrombus size in murine models of thrombosis following administration of recombinant alpha1-proteinase inhibitor mutant proteins Sheffield WP, Eltringham-Smith LJ, Bhakta V, Gataiance S 2012 Thromb Haemost View Researchers Basic research
SHP-1 protein tyrosine phosphatase associates with the adaptor protein CrkL Evren S, Ma XZ, Sakac D, Branch DR 2012 Exp Hematol View Researchers Basic research
Toward a prophylaxis against fetal and neonatal alloimmune thrombocytopenia: induction of antibody-mediated immune suppression and prevention of severe clinical complications in a murine model Tiller H, Killie MK, Chen P, Eksteen M, Husebekk A, Skogen B, Kjeldsen-Kragh J, Ni H 2012 Transfusion View Researchers Basic research
The platelet "sugar high" in diabetes Ni H 2012 Blood View Researchers Other
An analysis of the bias in red blood cell hemolysis measurement using several analytical approaches Acker JP, Croteau IM, Yi QL 2012 Clin Chim Acta View Researchers New or improved product or process
Expert approaches to common bleeding and thrombotic problems-part I Hayward CP, Webert KE 2012 Semin Thromb Hemost View Health care providers Other
Influence of polymer architecture on antigens camouflage, CD47 protection and complement mediated lysis of surface grafted red blood cells Chapanian R, Constantinescu I, Rossi NA, Medvedev N, Brooks DE, Scott MD, Kizhakkedathu JN 2012 Biomaterials View Researchers Basic research
The impact of increasing the upper age limit of donation on the eligible blood donor population in Canada Fan W, Yi QL, Xi G, Goldman M, Germain M, O'Brien SF 2012 Transfus Med View Blood operators New or improved product or process
Relative efficacy of steroid therapy in immune thrombocytopenia mediated by anti-platelet GPIIbIIIa versus GPIb? antibodies Zeng Q, Zhu L, Tao L, Bao J, Yang M, Simpson EK, Li C, van der Wal DE, Chen P, Spring CM, Wang M, Zhang L, Ruan C, Hou M, Xia R, Ni H 2012 Am J Hematol View Researchers Clinical research
The expanding family of bone marrow homing factors for hematopoietic stem cells: stromal derived factor 1 is not the only player in the game Ratajczak MZ, Kim C, Janowska-Wieczorek A, Ratajczak J 2012 ScientificWorldJournal View Researchers Basic research
The role of complement in the trafficking of hematopoietic stem/progenitor cells Janowska-Wieczorek A, Marquez-Curtis LA, Shirvaikar N, Ratajczak MZ 2012 Transfusion View Researchers Basic research
A prospective study measuring the development of antibodies against platelet factor 4-heparin in healthy males after exposure to heparins Kelton JG, Warkentin TE, Moore JC, Arnold DM, Nazi I, Arepally GM, Roach JM, Fier I 2012 J Thromb Haemost View Health care providers Clinical research
Changes in coagulation factor activity and content of di(2-ethylhexyl)phthalate in frozen plasma units during refrigerated storage for up to five days after thawing Sheffield WP, Bhakta V, Mastronardi C, Ramirez-Arcos S, Howe D, Jenkins C 2012 Transfusion View Health care providers New or improved product or process
Impact of Pandemic Influenza A (H1N1) on Laboratory Services Patel SN, Gubbay JB, Bastien N, Booth T, Charest H, Chernesky M, Couillard M, Drews S, Garceau R, Gubbay J, Guercio S, Fearon M, Fonseca K, Hatchette T, Horsman G, Larke B, Li Y, Majury A, Ouellette O, Petric M, Ratnam S, Sevenhuysen C, Van Caeseele P 2012 National Collaborating Centre for Infectious Diseases: Evidence Reviews on Pandemic H1N1 View Health care providers Other
Selective testing for Trypanosoma cruzi: the first year after implementation at Canadian Blood Services O'Brien SF, Scalia V, Goldman M, Fan W, Yi QL, Dines IR, Huang M, Ndao M, Fearon MA 2012 Transfusion View Blood operators New or improved product or process
Low-intensity pulsed ultrasound-mediated stimulation of hematopoietic stem/progenitor cell viability, proliferation and differentiation in vitro Xu P, Gul-Uludag H, Ang WT, Yang X, Huang M, Marquez-Curtis L, McGann L, Janowska-Wieczorek A, Xing J, Swanson E, Chen J 2012 Biotechnol Lett View Researchers Basic research
Platelet antibodies and fetal growth: maternal antibodies against fetal platelet antigen 1a are strongly associated with reduced birthweight in boys Tiller H, Killie MK, Husebekk A, Skogen B, Ni H, Kjeldsen-Kragh J, Olan P 2012 Acta Obstet Gyn Scan View Health care providers Clinical research
Riboflavin and ultraviolet light treatment potentiates vasodilator-stimulated phosphoprotein Ser-239 phosphorylation in platelet concentrates during storage Schubert P, Culibrk B, Coupland D, Scammell K, Gyongyossy-Issa M, Devine DV 2012 Transfusion View Researchers Basic research
Serratia marcescens strains implicated in adverse transfusion reactions form biofilms in platelet concentrates and demonstrate reduced detection by automated culture Greco-Stewart VS, Brown EE, Parr C, Kalab M, Jacobs MR, Yomtovian RA, Ramirez-Arcos SM 2012 Vox Sang View Blood operators Basic research
Donor motivation in Xi'an, China: comparison with Canadian donors O'Brien SF, Shao ZJ, Osmond L, Yi QL, Li CY, An QX 2012 Vox Sang View Blood operators Other
Herpesviruses enhance fibrin clot lysis Gershom ES, Vanden Hoek AL, Meixner SC, Sutherland MR, Pryzdial EL 2012 Thromb Haemost View Researchers Basic research
Kruppel-like factor 1 (KLF1), KLF2, and Myc control a regulatory network essential for embryonic erythropoiesis Pang CJ, Lemsaddek W, Alhashem YN, Bondzi C, Redmond LC, Ah-Son N, Dumur CI, Archer KJ, Haar JL, Lloyd JA, Trudel M 2012 Mol Cell Biol View Researchers Basic research