Our Research Publications

Updated August 2025

Title Authors Year Sort ascending Journal Link to Article Intended Audience Purpose
Using pharmacokinetics to individualize hemophilia therapy Iorio A 2017 Hematology Am Soc Hematol Educ Program Health care providers Clinical research
ResearchUnit: Where is the blood going? Understanding red blood cell utilization to inform policies Zeller M, Heddle N, Devine D 2017 Blood.ca website Other Other
The clinical significance of platelet microparticle-associated microRNAs Provost P 2017 Clin Chem Lab Med Researchers Basic research
Transfusion-related immunomodulation: review of the literature and implications for pediatric critical illness Muszynski JA, Spinella PC, Cholette JM, Acker JP, Hall MW, Juffermans NP, Kelly DP, Blumberg N, Nicol K, Liedel J, Doctor A, Remy KE, Tucci M, Lacroix J, Norris PJ, for the Pediatric Critical Care Blood Research Network 2017 Transfusion Health care providers Clinical research
Acute megakaryoblastic transformation from essential thrombocythemia Roshan TM, Rajput AB, Berardi P, Padmore R 2017 Hum Pathol Health care providers Clinical research
An international investigation into O red blood cell unit administration in hospitals: the GRoup O Utilization Patterns (GROUP) study Zeller MP, Barty R, Aandahl A, Apelseth TO, Callum J, Dunbar NM, Elahie A, Garritsen H, Hancock H, Kutner JM, Manukian B, Mizuta S, Okuda M, Pagano MB, Poglod R, Rushford K, Selleng K, Sorensen CH, Sprogoe U, Staves J, Weiland T, Wendel S, Wood EM, van de Watering L, van Wordragen-Vlaswinkel M, Ziman A, Jan Zwaginga J, Murphy MF, Heddle NM, Yazer MH 2017 Transfusion Health care providers Clinical research
Blood and clots quizlet 4: Antithrombotic Therapy for Atrial Fibrillation Tseng E, Shih A, de Wit K, Chan T 2017 CanadiEM website Health care providers Benchmarking and standard setting
From cytokines to pragmatic designs: changing paradigms Heddle NM 2017 Transfusion Researchers Clinical research
Problems with precaution: the transfusion medicine experience Wilson K, Atkinson KM, Fergusson DA, Brown A, Forster A, Murphy MS, Tinmouth AT, Keelan J 2017 J Risk Res Health care providers Ethical, legal and social implications research
ResearchUnit: Using immunocamouflage to increase transplantation safety Scott M 2017 Blood.ca website Other Other
The association between platelet transfusions and bleeding in critically ill patients with thrombocytopenia Arnold DM, Lauzier F, Albert M, Williamson D, Li N, Zarychanski R, Doig C, McIntyre L, Freitag A, Crowther M, Saunders L, Clarke F, Bellomo R, Qushmaq I, Lopes R, Heels-Ansdell D, Webert K, Cook D 2017 Res Pract Thromb Haemost Researchers Clinical research
Transfusion-related acute lung injury (TRALI) Petraszko T 2017 Blood.ca website Health care providers Other
ResearchUnit: Natural killers: when cells go wrong Ni H 2017 Blood.ca website Other Other
Survey for bacterial testing of platelet components in Latin America Ramirez-Arcos S, McDonald CP, Benjamin RJ, for the ISBT Working Party Transfusion Transmitted Infectious Diseases Bacterial Subgroup 2017 ISBT Sci Ser Blood operators New or improved product or process
Bacterial Contamination Ramirez-Arcos S, Goldman M 2017 Practical Transfusion Medicine, 5th Edition Health care providers Benchmarking and standard setting
Blood donor characteristics on transfusion outcomes-should obesity be assessed in future clinical trials?-reply Chasse M, Fergusson DA 2017 JAMA Intern Med Researchers Clinical research
Effect on gene expression of three allelic variants in GATA motifs of ABO, RHD, and RHCE regulatory elements Fennell K, Hoffman R, Yoshida K, Iwamoto S, Govender L, Vather K, Sookraj A, Jentsch U, Pambrun C, McAuley C, Keller M, Ochoa-Garay G 2017 Transfusion Researchers Basic research
Hydroxyethyl starch supplemented with ice recrystallization inhibitors greatly improves cryopreservation of human red blood cells Poisson J, Briard J, Turner TR, Acker J, Ben R 2017 BioProcessing Journal Researchers Basic research
Implementation of pathogen inactivation technology: How to make the best decisions? Devine DV 2017 Transfusion Blood operators New or improved product or process
ResearchUnit: Improving outcomes for patients with autoimmune platelet disorders Arnold D 2017 Blood.ca website Other Clinical research
Thrombotic microangiopathies: a general approach to diagnosis and management Arnold D, Patriquin C, Nazy I 2017 CMAJ Health care providers Clinical research
Two novel ABCG2 alleles resulting in a Jr (a-) phenotype Berardi P, Cote J, Vege S, Aeschlimann J, Cserti-Gazdewich C, Westhoff CM 2017 Transfusion Researchers Basic research
Vox Sanguinis International Forum on provision of granulocytes for transfusion and their clinical use Morton S, Stanworth S, Lozano M, Harrison SJ, Hong FS, Dennington P, McQuilten Z, Worel N, Compernolle V, Kutner JM, Yokoyama APH, Nahirniak S, Germain M, Hume H, Robitaille N, Wilson A, Tinmouth A, Massey E, Boulat C, Woimant G, Tiberghien P, Schulze TJ, Bux J, Pierelli L, Ballester C, Netelenbos T, West KA, Conry?Cantilena C, Eder A, Haley NR, Yazer M, Triulzi D 2017 Vox Sang Blood operators Clinical research
The immune-stimulation capacity of liposome-treated red blood cells da Silveira Cavalcante L, Branch DR, Duong TT, Yeung RSM, Acker JP, Holovati JL 2017 J Liposome Res Researchers Basic research
The Stem Cell Club - spearheading stem cell donor recruitment at medical schools across Canada Parmar S, Rikhraj K, Hartsook S, Afford M, Longmuir C, Brar R, Ladd A, Thatcher A, Cuperfain A, Tigert A, Arora N, Suppiah R, Mcintosh S, Devito V, Leigh J, Yu J, Naidu A, Wang G, Sedra S, Hanna Y, Aziz D, Winquist L, Cheon S, Fingrut W 2017 2017 CFMS Annual Review Health care providers Other
A highly purified form of staphylococcal protein A alleviates murine immune thrombocytopenia (ITP) Kapur R, Catalina MD, Aslam R, Speck ER, Francovitch RF, Semple JW 2017 Br J Haematol Researchers Basic research
Alternative methods of blood donor skin disinfection Ramirez-Arcos S, Taha M, Kou Y, Goldman M 2017 Blood.ca website Blood operators New or improved product or process
Circular of Information for the use of human blood components: Red Blood Cells, Leukocytes Reduced (LR) Jenkins C 2017 Blood.ca website Health care providers Benchmarking and standard setting
Mitigation of the threat posed to transfusion by donors traveling to Zika-affected areas: a Canadian risk-based approach Germain M, Delage G, O'Brien SF, Grégoire Y, Fearon M, Devine D 2017 Transfusion Blood operators Clinical research
Pathogen inactivation treatment of plasma and platelet concentrates and their predicted functionality in massive transfusion protocols Arbaeen AF, Schubert P, Serrano K, Carter CJ, Culibrk B, Devine DV 2017 Transfusion Researchers Basic research
T Regulatory Cells and Dendritic Cells Protect Against Transfusion-Related Acute Lung Injury via IL-10 Kapur R, Kim M, Aslam R, McVey MJ, Tabuchi A, Luo A, Liu J, Li Y, Shanmugabhavananthan S, Speck ER 2017 Blood Researchers Basic research
Using Raman spectroscopy to assess hemoglobin oxygenation in red blood cell concentrate: an objective proxy for morphological index to gauge the quality of stored blood? Atkins CG, Schulze HG, Chen D, Devine DV, Blades MW, Turner RF 2017 Analyst Researchers New or improved product or process
Red blood cell membrane water permeability increases with length of ex vivo storage Alshalani A, Acker JP 2017 Cryobiology Researchers Basic research
Residual risk of bacterial contamination of platelets: six years of experience with sterility testing Ramirez-Arcos S, DiFranco C, McIntyre T, Goldman M 2017 Transfusion Researchers New or improved product or process
Selection and characterization of a DNA aptamer inhibiting coagulation factor XIa Donkor DA, Bhakta V, Eltringham-Smith LJ, Stafford AR, Weitz JI, Sheffield WP 2017 Sci Rep Researchers Basic research
Virus-Platelet Associations Pryzdial ELG, Lin BH, Sutherland MR 2017 Platelets in Thrombotic and Non-Thrombotic Disorders: Pathophysiology, Pharmacology and Therapeutics: an Update Researchers Basic research
Development of standard definitions for surveillance of complications related to blood donation Goldman M, Land K, Robillard P, Wiersum-Osselton J 2016 Vox Sang Blood operators Benchmarking and standard setting
How do I interpret a confidence interval? O'Brien SF, Yi QL 2016 Transfusion Researchers Other
Rationale and Design of the Informing Fresh versus Old Red Cell Management (INFORM) Trial: An International Pragmatic Randomized Trial Eikelboom JW, Cook RJ, Barty R, Liu Y, Arnold DM, Crowther MA, Devereaux PJ, Ellis M, Figueroa P, Gallus A, Hirsh J, Kurz A, Roxby D, Sessler DI, Sharon Y, Sobieraj-Teague M, Warkentin TE, Webert KE, Heddle NM 2016 Transfus Med Rev Researchers Clinical research
ResearchUnit: Data mining 2: digging for deeper understanding of donors and transfusion outcome Fergusson DA, Acker J 2016 Blood.ca website Other Other
The M358R variant of α1-proteinase inhibitor inhibits coagulation factor VIIa Sheffield WP, Bhakta V 2016 Biochem Biophys Res Commun Researchers Basic research
QSAR accelerated discovery of potent ice recrystallization inhibitors Briard JG, Fernandez M, De Luna P, Woo TK, Ben RN 2016 Sci Rep Researchers Basic research
A study protocol for a randomised controlled trial evaluating clinical effects of platelet transfusion products: the Pathogen Reduction Evaluation and Predictive Analytical Rating Score (PREPAReS) trial Ypma PF, van der Meer PF, Heddle NM, van Hilten JA, Stijnen T, Middelburg RA, Hervig T, van der Bom JG, Brand A, Kerkhoffs JL 2016 BMJ Open Researchers Clinical research
Evaluating mesenchymal stem cell therapy for sepsis with preclinical meta-analyses prior to initiating a first-in-human trial Lalu MM, Sullivan KJ, Mei SHJ, Moher D, Straus A, Fergusson DA, Stewart DJ, Jazi M, MacLeod M, Winston B, Marshall J, Hutton B, Walley KR, McIntyre L 2016 eLife Researchers Clinical research
Reversible hemostatic properties of sulfabetaine/quaternary ammonium modified hyperbranched polyglycerol Wen J, Weinhart M, Lai B, Kizhakkedathu J, Brooks DE 2016 Biomaterials Researchers Basic research
Transfusion reactions: prevention, diagnosis, and treatment Delaney M, Wendel S, Bercovitz RS, Cid J, Cohn C, Dunbar NM, Apelseth TO, Popovsky M, Stanworth SJ, Tinmouth A, Van De Watering L, Waters JH, Yazer M, Ziman A 2016 Lancet Health care providers Clinical research
Acetylsalicyclic acid for the prevention and treatment of thromboembolic diseases Webert K, Kelton J 2016 Aspirin and related drugs Health care providers Clinical research
Applications of Liposomes in Biopreservation Da Silveira Cavalcante L, Holovati J, Acker J 2016 Multiscale technologies for cryomedicine: implementation from nano to macroscale Researchers Basic research
Manufacturing method affects mitochondrial DNA release and extracellular vesicle composition in stored red blood cells Bakkour S, Acker JP, Chafets DM, Inglis HC, Norris PJ, Lee TH, Busch MP 2016 Vox Sang Researchers Basic research
Transfusion of fresher vs older red blood cells in hospitalized patients: a systematic review and meta-analysis Alexander PE, Barty R, Fei Y, Vandvik PO, Pai M, Siemieniuk RA, Heddle NM, Blumberg N, McLeod SL, Liu J, Eikelboom JW, Guyatt GH 2016 Blood Researchers Clinical research