Our Research Publications

Updated August 2025

Title Authors Year Journal Link to Article Intended Audience Purpose
Platelet-Activating Antibodies Are Detectable at the Earliest Onset of Heparin-Induced Thrombocytopenia, With Implications for the Operating Characteristics of the Serotonin-Release Assay Warkentin TE, Arnold DM, Kelton JG, Sheppard J-AI, Smith JW, Nazy I 2018 Chest View Researchers Basic research
Chloride and other electrolyte concentrations in commonly available 5% albumin products Lai AT, Zeller MP, Millen T, Kavsak P, Szczeklik W, Elahie A, Alhazzani W, D'Aragon F, Jaeschke R, Lamontagne F, Karachi T, Cook D, Meade M, Rochwerg B 2018 Crit Care Med View Researchers Clinical research
Modeling the optimal ethnic composition of an adult stem cell registry Blake JT, McTaggart K, Killeen D 2018 Eur J Oper Res View Blood operators New or improved product or process
Transfusion requirements in cardiac surgery III (TRICS III): study design of a randomized controlled trial Shehata N, Whitlock R, Fergusson DA, Thorpe KE, MacAdams C, Grocott HP, Rubens F, Fremes S, Lellouche F, Bagshaw S, Royse A, Rosseel PM, Hare G, Medicis E, Hudson C, Belley-Cote E, Bainbridge D, Kent B, Shaw A, Byrne K, Syed S, Royse CF, McGuiness S, Hall J, Mazer CD 2018 J Cardiothorac Vasc Anesth View Researchers Clinical research
Utilization of frozen plasma, cryoprecipitate, and recombinant factor VIIa for children with hemostatic impairments: An audit of transfusion appropriateness Lieberman L, Lin Y, Cserti-Gazdewich C, Yi QL, Pendergrast J, Lau W, Callum J 2018 Pediatr Blood Cancer View Health care providers Clinical research
Antimicrobial peptides: an effective approach to prevent bacterial biofilm formation in platelet concentrates Alabdullatif M, Atreya CD, Ramirez-Arcos S 2018 Transfusion View Researchers New or improved product or process
La maladie hémolytique du foetus et du nouveau-né et thrombopénie immune périnatale Clarke G, Hannon J 2018 Guide de la pratique transfusionnelle View Health care providers Other
ResearchUnit: How does anti-D prevent hemolytic disease of the fetus and newborn? Lessons from a mouse model Lazarus A 2018 Blood.ca website View Other Other
Pharmacokinetics and the transition to extended half-life factor concentrates: communication from the SSC of the ISTH Ragni MV, Croteau SE, Morfini M, Cnossen MH, Iorio A 2018 J Thromb Haemost View Health care providers Basic research
Heparin-induced thrombocytopenia-associated thrombosis: from arterial to venous to venous limb gangrene Warkentin TE 2018 J Thromb Haemost View Health care providers Benchmarking and standard setting
MicroRNA-218-5p Promotes Endovascular Trophoblast Differentiation and Spiral Artery Remodeling Brki J, Dunk C, O'Brien J, Fu G, Nadeem L, Wang Y-l, Rosman D, Salem M, Shynlova O, Yougbare I, Ni H, Lye SJ, Peng C 2018 Mol Ther View Researchers Basic research
Rivaroxaban and dabigatran did not affect clotting profiles in plasma reconstituted with varying levels of autologous platelets to the same degree as heparin when evaluated using thromboelastography Gantioqui J, Stevic I, Atkinson H, Chan AKC 2018 Blood Coagul Fibrinolysis View Researchers Basic research
Systematic reviews do not adequately report or address missing outcome data in their analyses: a methodological survey Kahale LA, Diab B, Brignardello-Petersen R, Agarwal A, Mustafa RA, Kwong J, Neumann I, Li L, Lopes LC, Briel M, Busse JW, Iorio A, Vandvik PO, Alexander PE, Guyatt G, Akl EA 2018 J Clin Epidemiol View Researchers Other
Complications of a severe autoimmune hemolytic anemia crisis: transfusional iron overload and gangrenous cholecystitis Menchetti I, Lin Y, Cserti-Gazdewich C, Goldstein J, Law C, Lazarus A, Callum JL 2018 Transfusion View Researchers Clinical research
Association of blood IgG with tumor necrosis factor-alpha and clinical course of chronic lymphocytic leukemia Spaner DE, Venema R, Huang J, Norris P, Lazarus A, Wang G, Shi Y 2018 EBioMedicine View Health care providers Clinical research
A multicentred study to validate a consensus bleeding assessment tool developed by the biomedical excellence for safer transfusion collaborative for use in patients with haematological malignancy Dyer C, Alquist CR, Cole-Sinclair M, Curnow E, Dunbar NM, Estcourt LJ, Kaufman R, Kutner JM, McCullough J, McQuilten Z, Potiphar L, Rioux-Masse B, Slichter S, Tinmouth A, Webert K, Yokoyama AP, Stanworth SJ 2018 Vox Sang View Health care providers Clinical research
Concentré de recherche: Rôle du groupe sanguin dans le déclenchement d'une hémolyse après l'administration d'immunoglobulines Branch D 2018 Blood.ca website View Researchers Basic research
Pathogen inactivation strategies to improve blood safety: Let's not throw pathogen-reduced platelets out with their bath water Devine DV 2018 JAMA Oncol View Researchers New or improved product or process
Circular of information for the use of human blood components: Plasma components Jenkins C 2018 Blood.ca website View Health care providers Benchmarking and standard setting
Systematic review of rituximab for autoimmune diseases: a potential alternative to intravenous immune globulin MacIsaac J, Siddiqui R, Jamula E, Li N, Baker S, Webert KE, Evanovitch D, Heddle NM, Arnold DM 2018 Transfusion View Researchers Clinical research
Therapeutic Apheresis Pavenski K 2018 Clinical Guide to Transfusion View Health care providers Benchmarking and standard setting
Risk of acute kidney injury in patients randomized to a restrictive versus liberal approach to red blood cell transfusion in cardiac surgery: a substudy protocol of the transfusion requirements in cardiac surgery III noninferiority trial Garg AX, Shehata N, McGuinness S, Whitlock R, Fergusson D, Wald R, Parikh C, Bagshaw SM, Khanykin B, Gregory A, Syed S, Hare GMT, Cuerden MS, Thorpe KE, Hall J, Verma S, Roshanov PS, Sontrop JM, Mazer CD 2018 Can J Kidney Health Dis View Researchers Clinical research
Blood bag spiking procedure Shimla S, Jenkins C, McTaggart K 2018 Blood.ca website View Other Other
GPIb? is required for platelet-mediated hepatic thrombopoietin generation Xu M, Li J, Neves MAD, Zhu G, Carrim N, Yu R, Gupta S, Marshall J, Rotstein O, Peng J, Hou M, Kunishima S, Ware J, Branch DR, Lazarus A, Ruggeri ZM, Freedman J, Ni H 2018 Blood View Researchers Basic research
Adverse reactions reporting Chargé S, Young D 2018 Blood.ca website View Health care providers Other
Initial flow cytometric evaluation of the Clearllab lymphoid screen Hedley BD, Cheng G, Luider J, Kern W, Lozanski G, Chin-Yee I, Lowes LE, Keeney M, Careaga D, Magari R, Tejidor L 2018 Cytometry B Clin Cytom View Researchers Basic research
Maternal HPA-1a antibody level and its role in predicting the severity of Fetal/Neonatal Alloimmune Thrombocytopenia: a systematic review Kjaer M, Bertrand G, Bakchoul T, Massey E, Baker JM, Lieberman L, Tanael S, Greinacher A, Murphy MF, Arnold DM, Baidya S, Bussel J, Hume H, Kaplan C, Oepkes D, Ryan G, Savoia H, Shehata N, Kjeldsen-Kragh J, International Collaboration for Transfusion Medicine Guidelines 2018 Vox Sang View Researchers Clinical research
Clinical Outcomes and Red Blood Cell Storage Ning S, Heddle NM 2018 Hematologic Challenges in the Critically Ill View Other Other
Les concentrés de facteurs de coagulation Poon MC, Goodyear MD, Rydz N, Lee A 2018 Guide de la pratique transfusionnelle View Health care providers Other
Hemostatic efficacy of pathogen-inactivated versus untreated platelets: a randomized controlled trial van der Meer PF, Ypma PF, van Geloven N, van Hilten JA, van Wordragen-Vlaswinkel RJ, Eissen O, Zwaginga JJ, Trus M, Beckers EAM, te Boekhorst P, Tinmouth A, Lin Y, Hsia C, Lee D, Norris PJ, Goodrich RP, Brand A, Hervig T, Heddle NM, van der Bom JG, Kerkhoffs J-LH 2018 Blood View Researchers Clinical research
Changes in plasma unit distributions to hospitals over a 10-year period Seheult JN, Shaz B, Bravo M, Croxon H, Devine D, Doncaster C, Field S, Flanagan P, Germain M, Gregoire Y, Kamel H, Karafin M, Kelting N, Lewis M, O'Brien C, Murphy MF, Rossmann S, Sayers M, Shinar E, Takanashi M, Titlestad K, Yazer MH 2018 Transfusion View Blood operators Clinical research
rIgG1 Fc hexamer inhibits antibody-mediated autoimmune disease via effects on complement and FcgammaRs Spirig R, Campbell IK, Koernig S, Chen CG, Lewis BJB, Butcher R, Muir I, Taylor S, Chia J, Leong D, Simmonds J, Scotney P, Schmidt P, Fabri L, Hofmann A, Jordi M, Spycher MO, Cattepoel S, Brasseit J, Panousis C, Rowe T, Branch DR, Baz Morelli A, Kasermann F, Zuercher AW 2018 J Immunol View Researchers Basic research
Unrelated donor choices for allogeneic hematopoietic cell transplantation in Canada: an evaluation of factors influencing donor selection Greco-Stewart V, Kiernan J, Killeen D, Haun S, Mercer D, Young K, Liwski RS, Allan DS 2018 Transfusion View Health care providers Clinical research
Immune Globulin Products Harding R, Lazarus A 2018 Clinical Guide to Transfusion View Health care providers Other
Improving quality of care for patients with iron deficiency anemia presenting to the emergency department Khadadah F, Callum J, Shelton D, Lin Y 2018 Transfusion View Health care providers Clinical research
Cellular immune responses to platelet factor 4 and heparin complexes in patients with heparin-induced thrombocytopenia Nazy I, Clare R, Staibano P, Warkentin TE, Larché M, Moore JC, Smith JW, Whitlock RP, Kelton JG, Arnold DM 2018 J Thromb Haemost View Researchers Clinical research
Modulating Intracellular Ice Growth with Cell-Permeating Small-Molecule Ice Recrystallization Inhibitors Poisson JS, Acker JP, Briard JG, Meyer JE, Ben RN 2018 Langmuir View Researchers Basic research
Routine screening method for microparticles in platelet transfusions Millar D, Murphy L, Labrie A, Maurer-Spurej E 2018 J Vis Exp View Health care providers New or improved product or process
The Monocyte Monolayer Assay: Past, Present and Future Tong TN, Cen S, Branch DR 2018 Transfus Med Rev View Researchers Basic research
Managing antithrombotic therapy in immune thrombocytopenia: development of the TH2 risk assessment score Balitsky AK, Kelton JG, Arnold DM 2018 Blood View Researchers New or improved product or process
Focusing in on use of pharmacokinetic profiles in routine hemophilia care Croteau SE, Callaghan MU, Davis J, Dunn AL, Guerrera M, Khan O, Neufeld EJ, Raffini LJ, Recht M, Wang M, Iorio A 2018 Res Pract Thromb Haemost View Health care providers Clinical research
Core outcome set for gene therapy in haemophilia: Results of the coreHEM multistakeholder project Iorio A, Skinner MW, Clearfield E, Messner D, Pierce GF, Witkop M, Tunis S 2018 Haemophilia View Health care providers Clinical research
The first case of severe acute hemolytic transfusion reaction caused by anti-Sc2 Lemay A-S, Tong TN, Branch DR, Huang M, Sumner C, Oldfield L, Hawes J, Cserti-Gazdewich CM, Lau W 2018 Transfusion View Researchers Clinical research
Low-molecular-weight heparin venous thromboprophylaxis in critically ill patients with renal dysfunction: A subgroup analysis of the PROTECT trial Pai M, Adhikari NKJ, Ostermann M, Heels-Ansdell D, Douketis JD, Skrobik Y, Qushmaq I, Meade M, Guyatt G, Geerts W, Walsh MW, Crowther MA, Friedrich JO, Burry L, Bellomo R, Brandao da Silva N, Costa Filho R, Cox MJ, Alves Silva S, Cook DJ, on behalf of the PROTECT Investigators 2018 PLoS One View Researchers Clinical research
Ultraviolet-based pathogen inactivation systems: untangling the molecular targets activated in platelets Schubert P, Johnson L, Marks DC, Devine DV 2018 Front Med View Researchers Basic research
Intravenous immune globulin to prevent heparin-induced thrombocytopenia Warkentin TE, Climans TH, Morin P-A 2018 N Engl J Med View Health care providers Other
Does my complex patient have DIC? Shih A 2018 CanadiEM website View Health care providers Other
Targeting transfusion-related acute lung injury: the journey from basic science to novel therapies Semple JW, McVey MJ, Kim M, Rebetz J, Kuebler WM, Kapur R 2018 Crit Care Med View Researchers Basic research
Hemolytic Disease of the Fetus and Newborn and Perinatal Immune Thrombocytopenia Clarke G, Hannon J 2018 Clinical Guide to Transfusion View Health care providers Other
Concentré de recherche: Comment l'anti-D est-il capable d'empêcher la maladie hémolytique du foetus et du nouveau-né? Réponses à  l'aide d'un modèle murin Lazarus A 2018 Blood.ca website View Other Other