Our Research Publications

Updated August 2025

Title Authors Year Sort ascending Journal Link to Article Intended Audience Purpose
The effect of unmeasurable endogenous plasma factor activity levels on factor VIII dosing in patients with severe hemophilia A McEneny-King A, Chelle P, Iorio A, Edginton AN 2018 Thromb Res Health care providers Clinical research
A Retrospective Chart Review of Transfusion Practices in the Palliative Care Unit Setting Sirianni G, Perri G, Callum J, Gardner S, Berall A, Selby D 2018 Am J Hosp Palliat Care Researchers Clinical research
Erythrocyte saturation with IgG is required for inducing antibody-mediated immune suppression and impacts both erythrocyte clearance and antigen-modulation mechanisms Cruz-Leal Y, Marjoram D, Lazarus AH 2018 J Immunol Researchers Basic research
ResearchUnit: Patient blood group impacts susceptibility to IVIg-associated hemolysis Branch D 2018 Blood.ca website Researchers Basic research
A Deep Learning Method to Automatically Identify Reports of Scientifically Rigorous Clinical Research from the Biomedical Literature: Comparative Analytic Study Del Fiol G MM, Iorio A, Cotoi C, Haynes RB 2018 J Med Internet Res Researchers Clinical research
Circular of information for the use of human blood components: Platelets Jenkins C 2018 Blood.ca website Health care providers Benchmarking and standard setting
Aphérèse thérapeutique Pavenski K 2018 Guide de la pratique transfusionnelle Health care providers Benchmarking and standard setting
Systematic reviews of guidelines and studies for single versus multiple unit transfusion strategies Shih AW, Liu A, Elsharawi R, Crowther MA, Cook RJ, Heddle NM 2018 Transfusion Researchers Clinical research
Plerixafor effectively mobilizes CD56bright NK cells in blood, providing an allograft predicted to protect against GVHD Wong PPC, Kariminia A, Jones D, Eaves CJ, Foley R, Ivison S, Couban S, Schultz KR 2018 Blood Health care providers Clinical research
Signalement des réactions transfusionnelles indésirables Chargé S, Young D 2018 Blood.ca website Health care providers Other
Evaluation of the functional properties of cryopreserved buffy coat-derived monocytes for monocyte monolayer assay Kipkeu BJ, Shyian ML, da Silveira Cavalcante L, Duong TT, Yeung RSM, Binnington B, Branch DR, Acker JP, Holovati JL 2018 Transfusion Researchers Basic research
Concentré de recherche: Important rôle de la GPIba, une protéine plaquettaire, dans la régulation de la production hépatique de thrombopoiétine Ni H 2018 Blood.ca website Other Other
Concentrates for Hemostatic Disorders and Hereditary Angioedema Poon MC, Goodyear MD, Rydz N, Lee A 2018 Clinical Guide to Transfusion Health care providers Other
Severe hemolytic disease of the fetus and newborn due to allo-anti-D in a patient with a partial DEL phenotype arising from the variant allele described as RHD*148+1T (RHD*01EL.31) Turley E, McGowan EC, Hyland CA, Schoeman EM, Flower RL, Skoll A, Delisle MF, Nelson T, Clarke G, Au N 2018 Transfusion Researchers Clinical research
Chloride and other electrolyte concentrations in commonly available 5% albumin products Lai AT, Zeller MP, Millen T, Kavsak P, Szczeklik W, Elahie A, Alhazzani W, D'Aragon F, Jaeschke R, Lamontagne F, Karachi T, Cook D, Meade M, Rochwerg B 2018 Crit Care Med Researchers Clinical research
IgA deficiency Goldman M 2018 Blood.ca website Health care providers Benchmarking and standard setting
The efficacy and safety of topical tranexamic acid: A systematic review and meta-analysis Montroy J, Hutton B, Moodley P, Fergusson NA, Cheng W, Tinmouth A, Lavallee LT, Fergusson DA, Breau RH 2018 Transfus Med Rev Researchers Clinical research
Psychometric properties of the Patient Reported Outcomes, Burdens and Experiences (PROBE) questionnaire Chai-Adisaksopha C, Skinner MW, Curtis R, Frick N, Nichol MB, Noone D, O'Mahony B, Page D, Stonebraker J, Thabane L, Crowther M, Iorio A 2018 BMJ Open Researchers Clinical research
Antiplatelet antibody-induced thrombocytopenia does not correlate with megakaryocyte abnormalities in murine immune thrombocytopenia Guo L, Kapur R, Aslam R, Hunt K, Hou Y, Zufferey A, Speck ER, Rondina MT, Lazarus AH, Ni H, Semple JW 2018 Scand J Immunol Researchers Basic research
How do we diagnose immune thrombocytopenia in 2018? Kelton JG VJ, Arnold DM 2018 Hematology Am Soc Hematol Educ Program Health care providers Clinical research
Past, present and future of haemophilia gene therapy: From vectors and transgenes to known and unknown outcomes Pierce GF, Iorio A 2018 Haemophilia Health care providers New or improved product or process
Concurrence of symmetrical peripheral gangrene and venous limb gangrene following polytrauma: a case report Tan JH, Mohamad Y, Tan CLH, Kassim M, Warkentin TE 2018 J Med Case Rep Health care providers Clinical research
Transfusion Safety: The Nature and Outcomes of Errors in Patient Registration Cohen R, Ning S, Yan MTS, Callum J 2018 Transfus Med Rev Health care providers Clinical research
Performing and interpreting individual pharmacokinetic profiles in patients with Hemophilia A or B: Rationale and general considerations Iorio A, Edginton AN, Blanchette V, Blatny J, Boban A, Cnossen M, Collins P, Croteau SE, Fischer K, Hart DP, Ito S, Korth-Bradley J, Lethagen S, Lillicrap D, Makris M, Mathôt R, Morfini M, Neufeld EJ, Spears J 2018 Res Pract Thromb Haem Health care providers Clinical research
Hommes gais et don de sang : Un projet à  l'étude Otis J, Caruso J 2018 Fugues Other Other
Platelet-Activating Antibodies Are Detectable at the Earliest Onset of Heparin-Induced Thrombocytopenia, With Implications for the Operating Characteristics of the Serotonin-Release Assay Warkentin TE, Arnold DM, Kelton JG, Sheppard J-AI, Smith JW, Nazy I 2018 Chest Researchers Basic research
A multicentred study to validate a consensus bleeding assessment tool developed by the biomedical excellence for safer transfusion collaborative for use in patients with haematological malignancy Dyer C, Alquist CR, Cole-Sinclair M, Curnow E, Dunbar NM, Estcourt LJ, Kaufman R, Kutner JM, McCullough J, McQuilten Z, Potiphar L, Rioux-Masse B, Slichter S, Tinmouth A, Webert K, Yokoyama AP, Stanworth SJ 2018 Vox Sang Health care providers Clinical research
Modeling the optimal ethnic composition of an adult stem cell registry Blake JT, McTaggart K, Killeen D 2018 Eur J Oper Res Blood operators New or improved product or process
Transfusion requirements in cardiac surgery III (TRICS III): study design of a randomized controlled trial Shehata N, Whitlock R, Fergusson DA, Thorpe KE, MacAdams C, Grocott HP, Rubens F, Fremes S, Lellouche F, Bagshaw S, Royse A, Rosseel PM, Hare G, Medicis E, Hudson C, Belley-Cote E, Bainbridge D, Kent B, Shaw A, Byrne K, Syed S, Royse CF, McGuiness S, Hall J, Mazer CD 2018 J Cardiothorac Vasc Anesth Researchers Clinical research
Utilization of frozen plasma, cryoprecipitate, and recombinant factor VIIa for children with hemostatic impairments: An audit of transfusion appropriateness Lieberman L, Lin Y, Cserti-Gazdewich C, Yi QL, Pendergrast J, Lau W, Callum J 2018 Pediatr Blood Cancer Health care providers Clinical research
Antimicrobial peptides: an effective approach to prevent bacterial biofilm formation in platelet concentrates Alabdullatif M, Atreya CD, Ramirez-Arcos S 2018 Transfusion Researchers New or improved product or process
La maladie hémolytique du foetus et du nouveau-né et thrombopénie immune périnatale Clarke G, Hannon J 2018 Guide de la pratique transfusionnelle Health care providers Other
ResearchUnit: How does anti-D prevent hemolytic disease of the fetus and newborn? Lessons from a mouse model Lazarus A 2018 Blood.ca website Other Other
Pharmacokinetics and the transition to extended half-life factor concentrates: communication from the SSC of the ISTH Ragni MV, Croteau SE, Morfini M, Cnossen MH, Iorio A 2018 J Thromb Haemost Health care providers Basic research
Heparin-induced thrombocytopenia-associated thrombosis: from arterial to venous to venous limb gangrene Warkentin TE 2018 J Thromb Haemost Health care providers Benchmarking and standard setting
MicroRNA-218-5p Promotes Endovascular Trophoblast Differentiation and Spiral Artery Remodeling Brki J, Dunk C, O'Brien J, Fu G, Nadeem L, Wang Y-l, Rosman D, Salem M, Shynlova O, Yougbare I, Ni H, Lye SJ, Peng C 2018 Mol Ther Researchers Basic research
Rivaroxaban and dabigatran did not affect clotting profiles in plasma reconstituted with varying levels of autologous platelets to the same degree as heparin when evaluated using thromboelastography Gantioqui J, Stevic I, Atkinson H, Chan AKC 2018 Blood Coagul Fibrinolysis Researchers Basic research
Systematic reviews do not adequately report or address missing outcome data in their analyses: a methodological survey Kahale LA, Diab B, Brignardello-Petersen R, Agarwal A, Mustafa RA, Kwong J, Neumann I, Li L, Lopes LC, Briel M, Busse JW, Iorio A, Vandvik PO, Alexander PE, Guyatt G, Akl EA 2018 J Clin Epidemiol Researchers Other
Complications of a severe autoimmune hemolytic anemia crisis: transfusional iron overload and gangrenous cholecystitis Menchetti I, Lin Y, Cserti-Gazdewich C, Goldstein J, Law C, Lazarus A, Callum JL 2018 Transfusion Researchers Clinical research
Association of blood IgG with tumor necrosis factor-alpha and clinical course of chronic lymphocytic leukemia Spaner DE, Venema R, Huang J, Norris P, Lazarus A, Wang G, Shi Y 2018 EBioMedicine Health care providers Clinical research
Changes in plasma unit distributions to hospitals over a 10-year period Seheult JN, Shaz B, Bravo M, Croxon H, Devine D, Doncaster C, Field S, Flanagan P, Germain M, Gregoire Y, Kamel H, Karafin M, Kelting N, Lewis M, O'Brien C, Murphy MF, Rossmann S, Sayers M, Shinar E, Takanashi M, Titlestad K, Yazer MH 2018 Transfusion Blood operators Clinical research
Concentré de recherche: Rôle du groupe sanguin dans le déclenchement d'une hémolyse après l'administration d'immunoglobulines Branch D 2018 Blood.ca website Researchers Basic research
Pathogen inactivation strategies to improve blood safety: Let's not throw pathogen-reduced platelets out with their bath water Devine DV 2018 JAMA Oncol Researchers New or improved product or process
Circular of information for the use of human blood components: Plasma components Jenkins C 2018 Blood.ca website Health care providers Benchmarking and standard setting
Systematic review of rituximab for autoimmune diseases: a potential alternative to intravenous immune globulin MacIsaac J, Siddiqui R, Jamula E, Li N, Baker S, Webert KE, Evanovitch D, Heddle NM, Arnold DM 2018 Transfusion Researchers Clinical research
Therapeutic Apheresis Pavenski K 2018 Clinical Guide to Transfusion Health care providers Benchmarking and standard setting
Risk of acute kidney injury in patients randomized to a restrictive versus liberal approach to red blood cell transfusion in cardiac surgery: a substudy protocol of the transfusion requirements in cardiac surgery III noninferiority trial Garg AX, Shehata N, McGuinness S, Whitlock R, Fergusson D, Wald R, Parikh C, Bagshaw SM, Khanykin B, Gregory A, Syed S, Hare GMT, Cuerden MS, Thorpe KE, Hall J, Verma S, Roshanov PS, Sontrop JM, Mazer CD 2018 Can J Kidney Health Dis Researchers Clinical research
Blood bag spiking procedure Shimla S, Jenkins C, McTaggart K 2018 Blood.ca website Other Other
GPIb? is required for platelet-mediated hepatic thrombopoietin generation Xu M, Li J, Neves MAD, Zhu G, Carrim N, Yu R, Gupta S, Marshall J, Rotstein O, Peng J, Hou M, Kunishima S, Ware J, Branch DR, Lazarus A, Ruggeri ZM, Freedman J, Ni H 2018 Blood Researchers Basic research
Adverse reactions reporting Chargé S, Young D 2018 Blood.ca website Health care providers Other